ZA200907643B - Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof - Google Patents

Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Info

Publication number
ZA200907643B
ZA200907643B ZA2009/07643A ZA200907643A ZA200907643B ZA 200907643 B ZA200907643 B ZA 200907643B ZA 2009/07643 A ZA2009/07643 A ZA 2009/07643A ZA 200907643 A ZA200907643 A ZA 200907643A ZA 200907643 B ZA200907643 B ZA 200907643B
Authority
ZA
South Africa
Prior art keywords
methylpyrrolidine
preparing
processes
tartrate salts
tartrate
Prior art date
Application number
ZA2009/07643A
Other languages
English (en)
Inventor
Michael Christie
Joseph James Petraitis
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of ZA200907643B publication Critical patent/ZA200907643B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA2009/07643A 2007-05-03 2009-10-30 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof ZA200907643B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03
PCT/US2008/005702 WO2008137087A1 (en) 2007-05-03 2008-05-02 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Publications (1)

Publication Number Publication Date
ZA200907643B true ZA200907643B (en) 2014-03-26

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2009/07643A ZA200907643B (en) 2007-05-03 2009-10-30 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Country Status (14)

Country Link
EP (1) EP2152669A1 (cg-RX-API-DMAC7.html)
JP (1) JP5698887B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100017565A (cg-RX-API-DMAC7.html)
CN (1) CN101679237A (cg-RX-API-DMAC7.html)
AU (1) AU2008248168B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0810330A2 (cg-RX-API-DMAC7.html)
CA (1) CA2686033A1 (cg-RX-API-DMAC7.html)
EA (1) EA019031B1 (cg-RX-API-DMAC7.html)
IL (1) IL201627A (cg-RX-API-DMAC7.html)
MX (1) MX2009011787A (cg-RX-API-DMAC7.html)
NZ (1) NZ580948A (cg-RX-API-DMAC7.html)
UA (1) UA99913C2 (cg-RX-API-DMAC7.html)
WO (1) WO2008137087A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200907643B (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008013838A2 (en) 2006-07-25 2008-01-31 Cephalon, Inc. Pyridizinone derivatives
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
MX2010008384A (es) * 2008-01-30 2010-11-30 Cephalon Inc Derivados de piridazina substituida, con actividad antagonista de h3 de histamina.
JP6849594B2 (ja) * 2014-12-23 2021-03-24 セファロン、インク. 縮合二環式2,4−ジアミノピリミジン誘導体を調整する方法
CN112638869B (zh) * 2018-09-07 2025-04-25 赛诺菲 6-(2,4-二氯苯基)-5-[4-[(3s)-1-(3-氟丙基)吡咯烷-3-基]氧基苯基]-8,9-二氢-7h-苯并[7]轮烯-2-甲酸甲酯的盐及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (de) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen Herstellung von hydrierten nitrilkautschuken
DE3433392A1 (de) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer
FR2714849B1 (fr) 1994-01-13 1996-04-05 Inst Francais Du Petrole Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique.
DE4403479A1 (de) 1994-02-04 1995-08-10 Basf Ag Verfahren zur Herstellung von Hydroxylammoniumsalzen
WO2004024707A2 (en) * 2002-09-16 2004-03-25 Abbott Laboratories Process for preparing amine type substituted benzofurans
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
EP1739104B1 (en) 2004-03-08 2014-07-09 Japan Science and Technology Agency Polymer-supported metal cluster compositions
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
CA2566526C (en) 2004-06-02 2012-10-23 F. Hoffmann-La Roche Ag Naphthaline derivatives useful as histamine-3-receptor ligands
WO2006059778A1 (ja) 2004-12-01 2006-06-08 Banyu Pharmaceutical Co., Ltd. 置換ピリドン誘導体
ATE496892T1 (de) 2004-12-17 2011-02-15 Janssen Pharmaceutica Nv Tetrahydroisochinolinverbindungen zur behandlung von zns-erkrankungen
MX2007008843A (es) 2005-01-21 2007-08-22 Schering Corp Derivados de imidazol y bencimidazol utiles como antagonistas de histamina h3.
JP2008534542A (ja) 2005-03-31 2008-08-28 ユセベ ファルマ ソシエテ アノニム オキサゾール部分又はチアゾール部分を含む化合物、それらの製造方法及びそれらの使用
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
CA2627234A1 (en) 2005-10-27 2007-05-03 Ucb Pharma, S.A. Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
DK1988777T3 (da) 2006-02-09 2012-01-16 Athersys Inc Pyrazoler til behandling af fedme og andre cns-lidelser
WO2007099423A1 (en) 2006-03-02 2007-09-07 Pfizer Products Inc. 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists
EP2007749A2 (en) 2006-03-13 2008-12-31 Pfizer Products Inc. Tetralines antagonists of the h-3 receptor
EP2035372A1 (en) 2006-06-29 2009-03-18 Arena Pharmaceuticals, Inc. Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto
WO2008013838A2 (en) 2006-07-25 2008-01-31 Cephalon, Inc. Pyridizinone derivatives

Also Published As

Publication number Publication date
CN101679237A (zh) 2010-03-24
UA99913C2 (ru) 2012-10-25
AU2008248168A1 (en) 2008-11-13
IL201627A0 (en) 2010-05-31
CA2686033A1 (en) 2008-11-13
WO2008137087A1 (en) 2008-11-13
JP5698887B2 (ja) 2015-04-08
EP2152669A1 (en) 2010-02-17
KR20100017565A (ko) 2010-02-16
AU2008248168B2 (en) 2013-03-21
IL201627A (en) 2014-06-30
BRPI0810330A2 (pt) 2014-10-14
NZ580948A (en) 2011-04-29
JP2010526142A (ja) 2010-07-29
EA200971019A1 (ru) 2010-04-30
EA019031B1 (ru) 2013-12-30
MX2009011787A (es) 2009-11-13

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