ZA200906433B - Recombinant expression vectors elements (reves) for enchancing expression of recombinant proteins in host cells - Google Patents
Recombinant expression vectors elements (reves) for enchancing expression of recombinant proteins in host cellsInfo
- Publication number
- ZA200906433B ZA200906433B ZA2009/06433A ZA200906433A ZA200906433B ZA 200906433 B ZA200906433 B ZA 200906433B ZA 2009/06433 A ZA2009/06433 A ZA 2009/06433A ZA 200906433 A ZA200906433 A ZA 200906433A ZA 200906433 B ZA200906433 B ZA 200906433B
- Authority
- ZA
- South Africa
- Prior art keywords
- recombinant
- expression
- reves
- enchancing
- host cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92114107P | 2007-03-30 | 2007-03-30 | |
PCT/US2008/004063 WO2008121324A2 (en) | 2007-03-30 | 2008-03-28 | Recombinant expression vector elements (reves) for enhancing expression of recombinant proteins in host cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200906433B true ZA200906433B (en) | 2014-03-26 |
Family
ID=39795081
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA2009/06433A ZA200906433B (en) | 2007-03-30 | 2009-09-15 | Recombinant expression vectors elements (reves) for enchancing expression of recombinant proteins in host cells |
Country Status (16)
Country | Link |
---|---|
US (2) | US7935808B2 (en) |
EP (1) | EP2142560A4 (en) |
JP (2) | JP5432117B2 (en) |
KR (2) | KR20100014724A (en) |
CN (1) | CN101652379B (en) |
AU (1) | AU2008233196B2 (en) |
BR (1) | BRPI0809361A2 (en) |
CA (1) | CA2681581A1 (en) |
IL (1) | IL201231A0 (en) |
MX (1) | MX2009010492A (en) |
NZ (1) | NZ580378A (en) |
RU (1) | RU2518340C2 (en) |
SG (1) | SG182953A1 (en) |
TW (1) | TW200907059A (en) |
WO (1) | WO2008121324A2 (en) |
ZA (1) | ZA200906433B (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100014724A (en) * | 2007-03-30 | 2010-02-10 | 아보트 러보러터리즈 | Recombinant expression vector elements(reves) for enhancing expression of recombinant proteins in host cells |
JP5808249B2 (en) * | 2008-10-20 | 2015-11-10 | アッヴィ・インコーポレイテッド | Antibody isolation and purification using protein A affinity chromatography |
ES2440321T3 (en) | 2009-02-27 | 2014-01-28 | Novartis Ag | Methods to select eukaryotic cells that express a heterologous protein |
JP2013502217A (en) * | 2009-08-17 | 2013-01-24 | ノックス テクノロジーズ インコーポレイテッド | Cloning and expression of arNOX protein 9-transmembrane superfamily (TM9SF), method and use |
AU2010313395A1 (en) | 2009-10-30 | 2012-05-10 | Abbvie Inc. | sORF constructs and multiple gene expression |
SG10201601882PA (en) | 2011-12-22 | 2016-04-28 | Hoffmann La Roche | Expression Vector Organization, Novel Production Cell Generation Methods And Their Use For The Recombinant Production Of Polypeptides |
EP3354660A1 (en) * | 2011-12-22 | 2018-08-01 | F. Hoffmann-La Roche AG | Expression vector element combinations, novel production cell generation methods and their use for the recombinant production of polypeptides |
WO2013175491A2 (en) * | 2012-03-30 | 2013-11-28 | Biogenomics Limited | Stable expression system for eukaryotic cells |
KR102073748B1 (en) | 2013-01-31 | 2020-02-05 | 한미약품 주식회사 | Recombinant yeast transformant and process for preparing immunoglobulin Fc fragment employing the same |
WO2015017823A1 (en) * | 2013-08-02 | 2015-02-05 | The Uab Research Foundation | Tetravalent pneumococcal serogroup 6z |
RU2546249C2 (en) | 2013-08-07 | 2015-04-10 | Силезиа Груп Пте. Лтд. | Composition for amplification of transgene expression in eucariotic cells, and method for increasing generation of target protein coded with transgene |
JP6526025B2 (en) | 2013-10-16 | 2019-06-05 | オンコバイオロジクス,インコーポレイティド | Buffer solution formulation for enhancing antibody stability |
WO2016118707A1 (en) | 2015-01-21 | 2016-07-28 | Oncobiologics, Inc. | Modulation of charge variants in a monoclonal antibody composition |
WO2016151599A1 (en) | 2015-03-25 | 2016-09-29 | Biogenomics Limited | A bigenic mammalian expression vector |
AU2017213775A1 (en) | 2016-02-03 | 2018-08-16 | Outlook Therapeutics, Inc. | Buffer formulations for enhanced antibody stability |
WO2019055471A1 (en) * | 2017-09-18 | 2019-03-21 | Amyris, Inc. | Methods for producing full-length antibodies |
WO2020006486A1 (en) * | 2018-06-29 | 2020-01-02 | Krystal Biotech, Inc. | Compositions and methods for antibody delivery |
PT115073A (en) | 2018-10-09 | 2020-05-29 | Inst De Biologia Molecular E Celular Ibmc | NUCLEIC ACID TO ACTIVATE PROTEIN EXPRESSION AND PRODUCTION |
CN110592090A (en) * | 2019-10-30 | 2019-12-20 | 福建师范大学 | SSA4 gene promoter and pichia pastoris expression vector for driving exogenous gene transcription by using same |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2052027T5 (en) | 1988-11-11 | 2005-04-16 | Medical Research Council | IMMUNOGLOBULINE VARIABLE DOMAIN SEQUENCE CLONING. |
US6596514B2 (en) | 1996-01-11 | 2003-07-22 | Immunex Corporation | Expression augmenting sequence elements (EASE) for eukaryotic expression systems |
DE69730592T2 (en) | 1996-01-11 | 2005-09-29 | Immunex Corp., Thousand Oaks | EXPRESSION-GROWING SEQUENCE ELEMENTS FOR EUKARYONTIC EXPRESSION SYSTEMS |
US6197591B1 (en) * | 1998-09-14 | 2001-03-06 | Pfizer Inc. | Streptomyces avermitilis regulatory genes for increased avermectin production |
SG141239A1 (en) | 2001-01-26 | 2008-04-28 | Selexis Sa | Matrix attachment regions and methods for use thereof |
ATE496134T1 (en) * | 2002-03-29 | 2011-02-15 | Xoma Technology Ltd | MULTIGENE VECTORS AND METHODS FOR INCREASED EXPRESSION OF RECOMBINANT POLYPEPTIDES |
US7326567B2 (en) * | 2003-11-12 | 2008-02-05 | Schering Corporation | Plasmid system for multigene expression |
SG2014010029A (en) | 2005-08-19 | 2014-08-28 | Abbott Lab | Dual variable domain immunoglobin and uses thereof |
SI3339445T1 (en) * | 2006-09-08 | 2020-12-31 | Abbvie Bahamas Ltd. | Interleukin -13 binding proteins |
KR20100014724A (en) * | 2007-03-30 | 2010-02-10 | 아보트 러보러터리즈 | Recombinant expression vector elements(reves) for enhancing expression of recombinant proteins in host cells |
-
2008
- 2008-03-28 KR KR1020097020529A patent/KR20100014724A/en not_active Application Discontinuation
- 2008-03-28 JP JP2010501006A patent/JP5432117B2/en not_active Expired - Fee Related
- 2008-03-28 KR KR1020137015533A patent/KR20140001229A/en not_active Application Discontinuation
- 2008-03-28 TW TW097111615A patent/TW200907059A/en unknown
- 2008-03-28 BR BRPI0809361-0A patent/BRPI0809361A2/en not_active IP Right Cessation
- 2008-03-28 EP EP08727191A patent/EP2142560A4/en not_active Withdrawn
- 2008-03-28 MX MX2009010492A patent/MX2009010492A/en active IP Right Grant
- 2008-03-28 CA CA002681581A patent/CA2681581A1/en not_active Abandoned
- 2008-03-28 US US12/079,748 patent/US7935808B2/en active Active
- 2008-03-28 NZ NZ580378A patent/NZ580378A/en not_active IP Right Cessation
- 2008-03-28 AU AU2008233196A patent/AU2008233196B2/en not_active Ceased
- 2008-03-28 CN CN200880011023.5A patent/CN101652379B/en not_active Expired - Fee Related
- 2008-03-28 WO PCT/US2008/004063 patent/WO2008121324A2/en active Application Filing
- 2008-03-28 RU RU2009140146/10A patent/RU2518340C2/en not_active IP Right Cessation
- 2008-03-28 SG SG2012046504A patent/SG182953A1/en unknown
-
2009
- 2009-09-15 ZA ZA2009/06433A patent/ZA200906433B/en unknown
- 2009-09-29 IL IL201231A patent/IL201231A0/en unknown
-
2011
- 2011-04-29 US US13/098,337 patent/US8410259B2/en active Active
-
2013
- 2013-08-22 JP JP2013171957A patent/JP2014012014A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20080241883A1 (en) | 2008-10-02 |
AU2008233196B2 (en) | 2011-10-13 |
EP2142560A2 (en) | 2010-01-13 |
AU2008233196A1 (en) | 2008-10-09 |
CN101652379B (en) | 2014-05-14 |
US8410259B2 (en) | 2013-04-02 |
CN101652379A (en) | 2010-02-17 |
RU2009140146A (en) | 2011-05-10 |
US7935808B2 (en) | 2011-05-03 |
WO2008121324A2 (en) | 2008-10-09 |
KR20100014724A (en) | 2010-02-10 |
IL201231A0 (en) | 2010-05-31 |
JP2014012014A (en) | 2014-01-23 |
EP2142560A4 (en) | 2010-12-01 |
JP2010523082A (en) | 2010-07-15 |
RU2518340C2 (en) | 2014-06-10 |
US20110201053A1 (en) | 2011-08-18 |
SG182953A1 (en) | 2012-08-30 |
JP5432117B2 (en) | 2014-03-05 |
NZ580378A (en) | 2012-11-30 |
WO2008121324A3 (en) | 2008-12-11 |
MX2009010492A (en) | 2009-10-19 |
BRPI0809361A2 (en) | 2014-09-02 |
KR20140001229A (en) | 2014-01-06 |
CA2681581A1 (en) | 2008-10-09 |
TW200907059A (en) | 2009-02-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200906433B (en) | Recombinant expression vectors elements (reves) for enchancing expression of recombinant proteins in host cells | |
HK1250518A1 (en) | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof | |
AU2016202426A1 (en) | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof | |
ZA201204383B (en) | Expression of hexose kinase in recombinant host cells | |
ZA201001933B (en) | Cell-permeabilising peptides and polypeptides for microbial cells | |
IL202213A0 (en) | Recombinant protein production in avian ebxr cells | |
EP2315833B8 (en) | Vectors for delivery of light-sensitive proteins and methods of use | |
HRP20190025T1 (en) | Recombinant bacterial host cell for protein expression | |
EP2406038A4 (en) | Abrasive articles including fused zirconia alumina grain having an improved shape | |
EP2593469A4 (en) | Modified polypeptides and proteins and uses thereof | |
EP2242840A4 (en) | Recombinant virus production using mammalian cells in suspension | |
EP2376647A4 (en) | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system | |
EP2242505A4 (en) | Glycoconjugation of polypeptides using oligosaccharyltransferases | |
EP2246064A4 (en) | Recombinant ganoderma lucidium immunomodulatory protein (rlz-8) and uses thereof | |
DK2089524T3 (en) | DNase expression in recombinant host cells | |
BR112014031039A2 (en) | recombinant DNA elements for the expression of recombinant proteins in a host cell. | |
EP2935581A4 (en) | Expression vectors for recombinant protein production in mammalian cells | |
EP2504357A4 (en) | Recombinant filaggrin polypeptides for cell importation | |
EP2245160A4 (en) | Cell surface display of proteins | |
EP2598636A4 (en) | Vectors and methods for recombinant protein expression | |
PL2443232T3 (en) | System for the heterologous expression of a viral protein in a ciliate host cell | |
EP2274418A4 (en) | Human host cell for producing recombinant proteins with high quality and quantity | |
GB0725201D0 (en) | Peptide fusion proteins | |
HK1154046A1 (en) | Methods and compositions for production of recombinant protein in hbx- expressing mammalian cells hbx | |
EP2382317A4 (en) | Tor-interacting proteins (tips) and genes therefor |