ZA200807397B - Nanoparticulate carvedilol formulations - Google Patents

Nanoparticulate carvedilol formulations

Info

Publication number
ZA200807397B
ZA200807397B ZA200807397A ZA200807397A ZA200807397B ZA 200807397 B ZA200807397 B ZA 200807397B ZA 200807397 A ZA200807397 A ZA 200807397A ZA 200807397 A ZA200807397 A ZA 200807397A ZA 200807397 B ZA200807397 B ZA 200807397B
Authority
ZA
South Africa
Prior art keywords
nanoparticulate carvedilol
carvedilol formulations
formulations
nanoparticulate
carvedilol
Prior art date
Application number
ZA200807397A
Other languages
English (en)
Inventor
Liversidge Gary
Jenkins Scott
Original Assignee
Elan Pharma Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharma Int Ltd filed Critical Elan Pharma Int Ltd
Publication of ZA200807397B publication Critical patent/ZA200807397B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200807397A 2006-02-28 2008-08-27 Nanoparticulate carvedilol formulations ZA200807397B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/363,266 US8367112B2 (en) 2006-02-28 2006-02-28 Nanoparticulate carverdilol formulations

Publications (1)

Publication Number Publication Date
ZA200807397B true ZA200807397B (en) 2009-06-24

Family

ID=38444300

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200807397A ZA200807397B (en) 2006-02-28 2008-08-27 Nanoparticulate carvedilol formulations

Country Status (12)

Country Link
US (1) US8367112B2 (xx)
EP (1) EP1996161A2 (xx)
JP (1) JP2009528349A (xx)
KR (1) KR20080105114A (xx)
CN (1) CN101426477A (xx)
AU (1) AU2007221471A1 (xx)
BR (1) BRPI0708343A2 (xx)
CA (1) CA2643492A1 (xx)
IL (1) IL193692A0 (xx)
MX (1) MX2008011069A (xx)
WO (1) WO2007100466A2 (xx)
ZA (1) ZA200807397B (xx)

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HUE032426T2 (en) 2009-05-27 2017-09-28 Alkermes Pharma Ireland Ltd Inhibition of flake aggregation in nanoparticulate meloxicam formulations
US10267796B2 (en) * 2010-10-25 2019-04-23 The Procter & Gamble Company Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis
CN109106725A (zh) 2011-02-11 2019-01-01 Zs制药公司 用于治疗高钾血症的微孔性的硅酸锆
US9819635B2 (en) 2012-01-30 2017-11-14 International Business Machines Corporation System and method for message status determination
US9943637B2 (en) 2012-06-11 2018-04-17 ZS Pharma, Inc. Microporous zirconium silicate and its method of production
US9707255B2 (en) 2012-07-11 2017-07-18 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia in hypercalcemic patients and improved calcium-containing compositions for the treatment of hyperkalemia
US10695365B2 (en) 2012-10-22 2020-06-30 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia
WO2014066407A1 (en) 2012-10-22 2014-05-01 ZS Pharma, Inc. Microporous zirconium silicate for treating hyperkalemia
WO2014137797A2 (en) * 2013-03-04 2014-09-12 Transtech Pharma, Llc Stable glucokinase activator compositions
US9592253B1 (en) 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
JP2019521979A (ja) * 2016-06-13 2019-08-08 アセンディア ファーマシューティカルズ,エルエルシー カルベジロール分散系の非経口徐放送達
US11311529B2 (en) 2018-11-08 2022-04-26 Varsona Therapeutics, Inc. Topical formulations of 5-α-reductase inhibitors and uses thereof
US10772869B1 (en) 2019-07-24 2020-09-15 ECI Pharmaceuticals, LLC Pharmaceutical compositions including carvedilol and methods of using the same
US11311556B2 (en) * 2020-05-13 2022-04-26 Varsona Therapeutics, Inc. Topical dutasteride emulsions for treating endocrine therapy-induced alopecia
KR102525298B1 (ko) 2020-12-30 2023-04-25 단국대학교 천안캠퍼스 산학협력단 경구 생체이용률이 증가된 주석산을 포함하는 카베디롤 함유 고체분산체 및 이의 제조방법
KR102492147B1 (ko) 2020-12-30 2023-01-26 단국대학교 천안캠퍼스 산학협력단 자가나노유화 약물전달 시스템을 이용한 카베디롤 함유 경구용 고형제제 조성물 및 이의 제조방법
US20220168272A1 (en) * 2021-02-22 2022-06-02 Gholamhossein Yousefi Preparation of soluble form of carvedilol
CN117510510B (zh) * 2024-01-08 2024-03-19 中北大学 一种不易结块沙状乌洛托品的制备方法

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Also Published As

Publication number Publication date
JP2009528349A (ja) 2009-08-06
IL193692A0 (en) 2009-08-03
KR20080105114A (ko) 2008-12-03
US20070202180A1 (en) 2007-08-30
US8367112B2 (en) 2013-02-05
EP1996161A2 (en) 2008-12-03
WO2007100466A3 (en) 2007-11-29
CA2643492A1 (en) 2007-09-07
MX2008011069A (es) 2008-11-14
AU2007221471A1 (en) 2007-09-07
WO2007100466A2 (en) 2007-09-07
BRPI0708343A2 (pt) 2011-05-24
CN101426477A (zh) 2009-05-06

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