ZA200805198B - Pro-apoptotic bacteria and compositions for delivery and expression of antigens - Google Patents

Pro-apoptotic bacteria and compositions for delivery and expression of antigens

Info

Publication number
ZA200805198B
ZA200805198B ZA200805198A ZA200805198A ZA200805198B ZA 200805198 B ZA200805198 B ZA 200805198B ZA 200805198 A ZA200805198 A ZA 200805198A ZA 200805198 A ZA200805198 A ZA 200805198A ZA 200805198 B ZA200805198 B ZA 200805198B
Authority
ZA
South Africa
Prior art keywords
antigens
pro
expression
delivery
compositions
Prior art date
Application number
ZA200805198A
Other languages
English (en)
Inventor
Douglas S Kernodle
Original Assignee
Univ Vanderbilt
Us Gov As Represented By Dept
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt, Us Gov As Represented By Dept filed Critical Univ Vanderbilt
Publication of ZA200805198B publication Critical patent/ZA200805198B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200805198A 2005-11-15 2006-11-15 Pro-apoptotic bacteria and compositions for delivery and expression of antigens ZA200805198B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73752505P 2005-11-15 2005-11-15

Publications (1)

Publication Number Publication Date
ZA200805198B true ZA200805198B (en) 2010-01-27

Family

ID=38049292

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200805198A ZA200805198B (en) 2005-11-15 2006-11-15 Pro-apoptotic bacteria and compositions for delivery and expression of antigens

Country Status (6)

Country Link
US (1) US20090325298A1 (fr)
EP (1) EP1957652A4 (fr)
CN (1) CN101548015A (fr)
BR (1) BRPI0618672A2 (fr)
WO (1) WO2007059256A2 (fr)
ZA (1) ZA200805198B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012501189A (ja) * 2008-08-29 2012-01-19 バンダービルト ユニバーシティ 癌、結核、および線維化肺疾患の治療のためのマイコバクテリアの免疫原性を高める方法および組成物
US9248169B2 (en) * 2009-06-23 2016-02-02 Texas Tech University System Schistosomiasis vaccine compositions and methods of use
US9663758B2 (en) 2013-03-12 2017-05-30 Wisconsin Alumni Research Foundation Global gene regulators (GGR) as vaccine candidates against paratuberculosis
CN103497927B (zh) * 2013-10-21 2016-02-10 深圳大学 表达分泌金葡菌肠毒素蛋白的重组bcg活菌菌株、活菌疫苗及其构建方法和应用
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN116875520A (zh) * 2023-07-12 2023-10-13 吉林农业大学 表达核糖体失活蛋白的乳酸菌及其在抗轮状病毒中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999010493A1 (fr) * 1997-08-27 1999-03-04 The Government Of The United States Of America, Represented By The Secretary, Department Of Healtha Nd Human Services ADNc VARIANTS NEGATIFS DOMINANT ET ATTENUE DE Stat6: stat6b ET stat6c
AU7125400A (en) * 1999-09-10 2001-04-10 Trustees Of The University Of Pennsylvania, The Dominant negative neuropilin-1
US7399750B2 (en) * 2000-09-11 2008-07-15 The Regents Of The University Of California Methods for cardiac gene transfer
EP1361794B1 (fr) * 2001-02-07 2012-01-25 Vanderbilt University Vaccin bacterien pro-apoptotique augmentant la reponse immunitaire cellulaire

Also Published As

Publication number Publication date
BRPI0618672A2 (pt) 2011-09-06
WO2007059256A2 (fr) 2007-05-24
CN101548015A (zh) 2009-09-30
EP1957652A4 (fr) 2010-03-31
WO2007059256A3 (fr) 2009-05-22
US20090325298A1 (en) 2009-12-31
EP1957652A2 (fr) 2008-08-20

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