ZA200801928B - Injectable composite material suitable for use as a bone sustitute - Google Patents
Injectable composite material suitable for use as a bone sustituteInfo
- Publication number
- ZA200801928B ZA200801928B ZA200801928A ZA200801928A ZA200801928B ZA 200801928 B ZA200801928 B ZA 200801928B ZA 200801928 A ZA200801928 A ZA 200801928A ZA 200801928 A ZA200801928 A ZA 200801928A ZA 200801928 B ZA200801928 B ZA 200801928B
- Authority
- ZA
- South Africa
- Prior art keywords
- composite material
- material suitable
- bone
- sustitute
- injectable composite
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4601—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Prostheses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000549A ITTO20050549A1 (it) | 2005-08-03 | 2005-08-03 | Materiale composito iniettabile atto ad essere utilizzato come sostituto osseo |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200801928B true ZA200801928B (en) | 2009-07-29 |
Family
ID=37667630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200801928A ZA200801928B (en) | 2005-08-03 | 2006-08-01 | Injectable composite material suitable for use as a bone sustitute |
Country Status (22)
Country | Link |
---|---|
US (2) | US20080220086A1 (xx) |
EP (1) | EP1924302B1 (xx) |
JP (1) | JP5180075B2 (xx) |
KR (1) | KR101276632B1 (xx) |
CN (1) | CN101257937B (xx) |
AT (1) | ATE465762T1 (xx) |
AU (1) | AU2006274594B2 (xx) |
BR (1) | BRPI0615994A2 (xx) |
CA (1) | CA2617721A1 (xx) |
DE (1) | DE602006014004D1 (xx) |
DK (1) | DK1924302T3 (xx) |
ES (1) | ES2345399T3 (xx) |
IT (1) | ITTO20050549A1 (xx) |
NZ (1) | NZ566086A (xx) |
PL (1) | PL1924302T3 (xx) |
PT (1) | PT1924302E (xx) |
RU (1) | RU2407552C2 (xx) |
SI (1) | SI1924302T1 (xx) |
SM (1) | SMP200800013B (xx) |
UA (1) | UA92027C2 (xx) |
WO (1) | WO2007015208A2 (xx) |
ZA (1) | ZA200801928B (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
US20070098799A1 (en) * | 2005-10-28 | 2007-05-03 | Zimmer, Inc. | Mineralized Hydrogels and Methods of Making and Using Hydrogels |
CA2632120C (en) | 2005-12-07 | 2014-07-08 | Zimmer, Inc. | Methods of bonding or modifying hydrogels using irradiation |
US8110242B2 (en) | 2006-03-24 | 2012-02-07 | Zimmer, Inc. | Methods of preparing hydrogel coatings |
US7731988B2 (en) | 2007-08-03 | 2010-06-08 | Zimmer, Inc. | Multi-polymer hydrogels |
US8062739B2 (en) | 2007-08-31 | 2011-11-22 | Zimmer, Inc. | Hydrogels with gradient |
US7947784B2 (en) | 2007-11-16 | 2011-05-24 | Zimmer, Inc. | Reactive compounding of hydrogels |
US8034362B2 (en) | 2008-01-04 | 2011-10-11 | Zimmer, Inc. | Chemical composition of hydrogels for use as articulating surfaces |
US20100226956A1 (en) | 2009-03-06 | 2010-09-09 | Per Kjellin | Production of moldable bone substitute |
JP6952348B2 (ja) | 2015-07-24 | 2021-10-20 | トリンプ アイピー ピーティーワイ リミテッド | 殺菌性ポリマー及びポリマーと細胞との複合体ならびにそれらの合成 |
JP2020067494A (ja) * | 2018-10-22 | 2020-04-30 | ウェトラブ株式会社 | 脳神経外科手術用頭部モデル |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3635316B2 (ja) * | 1996-11-25 | 2005-04-06 | 株式会社アドバンス | 球状セラミックス多孔体の製造方法 |
US6949251B2 (en) | 2001-03-02 | 2005-09-27 | Stryker Corporation | Porous β-tricalcium phosphate granules for regeneration of bone tissue |
US20050049715A1 (en) * | 2001-10-21 | 2005-03-03 | Atsuo Ito | Porous article of sintered calclium phosphate, process for producing the same and artificial bone and histomorphological scaffold using the same |
PL1675608T3 (pl) * | 2003-09-12 | 2007-11-30 | Wyeth Corp | Stałe fosforanowo wapniowe pałeczki do wstrzyknięć dla dostarczania białek osteogennych |
-
2005
- 2005-08-03 IT IT000549A patent/ITTO20050549A1/it unknown
-
2006
- 2006-08-01 WO PCT/IB2006/052623 patent/WO2007015208A2/en active Application Filing
- 2006-08-01 PL PL06780262T patent/PL1924302T3/pl unknown
- 2006-08-01 ZA ZA200801928A patent/ZA200801928B/xx unknown
- 2006-08-01 KR KR1020087005280A patent/KR101276632B1/ko active IP Right Grant
- 2006-08-01 AU AU2006274594A patent/AU2006274594B2/en not_active Ceased
- 2006-08-01 RU RU2008108014/15A patent/RU2407552C2/ru not_active IP Right Cessation
- 2006-08-01 AT AT06780262T patent/ATE465762T1/de active
- 2006-08-01 DE DE602006014004T patent/DE602006014004D1/de active Active
- 2006-08-01 NZ NZ566086A patent/NZ566086A/en not_active IP Right Cessation
- 2006-08-01 UA UAA200802792A patent/UA92027C2/ru unknown
- 2006-08-01 PT PT06780262T patent/PT1924302E/pt unknown
- 2006-08-01 SM SM200800013T patent/SMP200800013B/it unknown
- 2006-08-01 BR BRPI0615994-0A patent/BRPI0615994A2/pt not_active Application Discontinuation
- 2006-08-01 CA CA002617721A patent/CA2617721A1/en not_active Abandoned
- 2006-08-01 US US11/997,211 patent/US20080220086A1/en not_active Abandoned
- 2006-08-01 EP EP06780262A patent/EP1924302B1/en active Active
- 2006-08-01 CN CN2006800286341A patent/CN101257937B/zh not_active Expired - Fee Related
- 2006-08-01 JP JP2008524655A patent/JP5180075B2/ja not_active Expired - Fee Related
- 2006-08-01 SI SI200630731T patent/SI1924302T1/sl unknown
- 2006-08-01 ES ES06780262T patent/ES2345399T3/es active Active
- 2006-08-01 DK DK06780262.9T patent/DK1924302T3/da active
-
2010
- 2010-12-28 US US12/979,818 patent/US8231909B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2006274594B2 (en) | 2011-12-22 |
EP1924302A2 (en) | 2008-05-28 |
UA92027C2 (ru) | 2010-09-27 |
JP5180075B2 (ja) | 2013-04-10 |
KR101276632B1 (ko) | 2013-06-18 |
ES2345399T3 (es) | 2010-09-22 |
RU2008108014A (ru) | 2009-09-10 |
ATE465762T1 (de) | 2010-05-15 |
BRPI0615994A2 (pt) | 2011-05-31 |
DK1924302T3 (da) | 2010-07-26 |
WO2007015208A3 (en) | 2007-05-31 |
CA2617721A1 (en) | 2007-02-08 |
ITTO20050549A1 (it) | 2007-02-04 |
AU2006274594A1 (en) | 2007-02-08 |
CN101257937A (zh) | 2008-09-03 |
EP1924302B1 (en) | 2010-04-28 |
SMAP200800013A (it) | 2008-02-27 |
SMP200800013B (it) | 2008-02-27 |
PL1924302T3 (pl) | 2010-10-29 |
KR20080041678A (ko) | 2008-05-13 |
US20110091554A1 (en) | 2011-04-21 |
RU2407552C2 (ru) | 2010-12-27 |
NZ566086A (en) | 2011-03-31 |
US20080220086A1 (en) | 2008-09-11 |
JP2009502405A (ja) | 2009-01-29 |
CN101257937B (zh) | 2013-03-20 |
DE602006014004D1 (de) | 2010-06-10 |
US8231909B2 (en) | 2012-07-31 |
PT1924302E (pt) | 2010-07-27 |
WO2007015208A2 (en) | 2007-02-08 |
SI1924302T1 (sl) | 2010-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200801928B (en) | Injectable composite material suitable for use as a bone sustitute | |
IL200392A (en) | Methods for preparing bone cement preparations containing phosphorus calcium for injection, bone cement preparations prepared using them, kits for their preparation and uses | |
PH12015501193A1 (en) | Boronate ester compounds and pharmaceutical compositions thereof | |
IL195341A0 (en) | Methods and materials for making simvastatin and related compounds | |
NZ612394A (en) | Tnf-α binding proteins | |
BR112012018620A2 (pt) | organismo microbiano de ocorrência não-natural, método para produzir (2-hidroxi-3-metil-4-oxobutoxi) fosfonato, método para produção de p-toluato, método para produzir tereftalato | |
TW200631917A (en) | Synthetic aggregates comprising sewage sludge and other waste materials and methods for producing such aggregates | |
CR20110606A (es) | Uso de un anticuerpo anti-tau ps422 para el tratamiento de enfermedades cerebrales | |
WO2012071141A3 (en) | Efficient virtual application update | |
GB2497475A (en) | Kits, components and methods for tissue reconstruction | |
MX2011008936A (es) | Anticuerpos que contienen peptidos terapeuticos mimeticos de tpo/epo. | |
WO2011038459A8 (en) | Remediation composition comprising alum sludge | |
GB2491323A (en) | Polymers of 8,9-Dihydrobenzo(DEF)Carbazole and their use as organic semiconductors | |
MX2009008471A (es) | Proceso para tratar sustancias contaminadas con metales pesados. | |
EA200800570A1 (ru) | Фосфонированные рифамицины и их применение для профилактики и лечения костных и суставных инфекций | |
DK2021043T3 (da) | Injicerbart fyldstof til knoglehulrum | |
GB0809592D0 (en) | Biomaterials | |
UA104875C2 (uk) | Препарат на основі синтетичних міметиків та спосіб одержання синтетичних міметиків (варіанти) | |
GEP20146180B (en) | Intermediate vapor collection within encapsulated control infrastructures | |
EA201300381A1 (ru) | Ориентированный коллаген/апатитовый материал и способ производства ориентированного коллаген/апатитового материала | |
AR078667A1 (es) | Moduladores de activador del factor de crecimiento de hepatocitos (hgfa) | |
AU2010251385A8 (en) | Novel solid materials of {[2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid} and methods for obtaining them | |
WO2011036326A3 (es) | Nuevos polímeros proteicos recombinantes y método de bioactivación de superficies con dichos polímeros | |
UA99579C2 (ru) | АНТИТЕЛО, КОТОРОЕ СВЯЗЫВАЕТСЯ С Tau, ФОСФОРИЛИРОВАННЫМ ПО СЕРИНУ 422 (pS422), ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ ТАУПАТИИ | |
WO2012044139A3 (ko) | 크립토탄신온의 신규 용도 |