ZA200707520B - Thiazolidnones for use as inhibitors of Polo-like kinase (Plk) - Google Patents
Thiazolidnones for use as inhibitors of Polo-like kinase (Plk)Info
- Publication number
- ZA200707520B ZA200707520B ZA200707520A ZA200707520A ZA200707520B ZA 200707520 B ZA200707520 B ZA 200707520B ZA 200707520 A ZA200707520 A ZA 200707520A ZA 200707520 A ZA200707520 A ZA 200707520A ZA 200707520 B ZA200707520 B ZA 200707520B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiazolidnones
- plk
- polo
- kinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- AIDS & HIV (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005005395A DE102005005395A1 (de) | 2005-02-03 | 2005-02-03 | Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200707520B true ZA200707520B (en) | 2008-11-26 |
Family
ID=36709709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200707520A ZA200707520B (en) | 2005-02-03 | 2007-08-31 | Thiazolidnones for use as inhibitors of Polo-like kinase (Plk) |
Country Status (18)
Country | Link |
---|---|
US (1) | US7511059B2 (es) |
EP (1) | EP1844027A1 (es) |
JP (1) | JP2008529985A (es) |
CN (1) | CN101155791A (es) |
AR (1) | AR052370A1 (es) |
AU (1) | AU2006210153A1 (es) |
BR (1) | BRPI0606140A2 (es) |
CA (1) | CA2596967A1 (es) |
DE (1) | DE102005005395A1 (es) |
DO (1) | DOP2006000024A (es) |
GT (1) | GT200600039A (es) |
MX (1) | MX2007009387A (es) |
PA (1) | PA8661701A1 (es) |
PE (1) | PE20061085A1 (es) |
TW (1) | TW200639155A (es) |
UY (1) | UY29358A1 (es) |
WO (1) | WO2006082107A1 (es) |
ZA (1) | ZA200707520B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0309758A (pt) * | 2002-05-03 | 2005-02-15 | Schering Ag | Tiazolidinonas e seu uso como inibidortes de cinase semelhante a polo |
US7553639B2 (en) * | 2006-01-31 | 2009-06-30 | Elan Pharma International Limited | Alpha-synuclein kinase |
US20110207796A1 (en) * | 2008-02-13 | 2011-08-25 | Elan Pharma International Limited | Alpha-synuclein kinase |
BRPI0919906A2 (pt) * | 2008-10-29 | 2016-02-16 | Fujifilm Corp | corante, elemento de conversão fotoelétrico e célula fotoeletroquímica cada uma compreendendo o corante e o processo para produzir corante. |
ES2465971T3 (es) | 2009-04-06 | 2014-06-09 | University Health Network | Inhibidores de quinasa y método para tratar cáncer con los mismos |
TWI516262B (zh) | 2010-04-06 | 2016-01-11 | 健康網路大學 | 激酶抑制劑及以其治療癌症的方法 |
ES2706066T3 (es) * | 2010-07-02 | 2019-03-27 | Univ Health Network | Procedimiento dirigido a enfermedades mutantes con PTEN y composiciones para las mismas |
WO2014069434A1 (ja) * | 2012-10-30 | 2014-05-08 | カルナバイオサイエンス株式会社 | 新規チアゾリジノン誘導体 |
LT3057965T (lt) * | 2013-10-18 | 2019-03-12 | University Health Network | Plk-4 inhibitoriaus druska ir jos kristalinės formos |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0309758A (pt) * | 2002-05-03 | 2005-02-15 | Schering Ag | Tiazolidinonas e seu uso como inibidortes de cinase semelhante a polo |
WO2004043936A1 (ja) | 2002-11-14 | 2004-05-27 | Kyowa Hakko Kogyo Co., Ltd. | Plk阻害剤 |
DE10351744A1 (de) * | 2003-10-31 | 2005-06-16 | Schering Ag | Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel |
JP2008524139A (ja) * | 2004-12-15 | 2008-07-10 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | メタ置換チアゾリノン類、それらの製造及び医薬としての使用 |
US20070010565A1 (en) * | 2005-04-25 | 2007-01-11 | Olaf Prien | New thiazolidinones without basic nitrogen, their production and use as pharmaceutical agents |
DE102005020104A1 (de) * | 2005-04-25 | 2006-10-26 | Schering Ag | Neue Thiazolidinone ohne basischen Stickstoff, deren Herstellung und Verwendung als Arzneimittel |
-
2005
- 2005-02-03 DE DE102005005395A patent/DE102005005395A1/de not_active Ceased
-
2006
- 2006-02-01 DO DO2006000024A patent/DOP2006000024A/es unknown
- 2006-02-01 AR ARP060100355A patent/AR052370A1/es unknown
- 2006-02-02 BR BRPI0606140-0A patent/BRPI0606140A2/pt not_active Application Discontinuation
- 2006-02-02 GT GT200600039A patent/GT200600039A/es unknown
- 2006-02-02 UY UY29358A patent/UY29358A1/es not_active Application Discontinuation
- 2006-02-02 CN CNA2006800111192A patent/CN101155791A/zh active Pending
- 2006-02-02 WO PCT/EP2006/001037 patent/WO2006082107A1/de active Application Filing
- 2006-02-02 US US11/345,666 patent/US7511059B2/en not_active Expired - Fee Related
- 2006-02-02 PE PE2006000130A patent/PE20061085A1/es not_active Application Discontinuation
- 2006-02-02 AU AU2006210153A patent/AU2006210153A1/en not_active Abandoned
- 2006-02-02 JP JP2007553562A patent/JP2008529985A/ja active Pending
- 2006-02-02 MX MX2007009387A patent/MX2007009387A/es not_active Application Discontinuation
- 2006-02-02 EP EP06706691A patent/EP1844027A1/de not_active Withdrawn
- 2006-02-02 CA CA002596967A patent/CA2596967A1/en not_active Abandoned
- 2006-02-03 TW TW095103845A patent/TW200639155A/zh unknown
- 2006-02-03 PA PA20068661701A patent/PA8661701A1/es unknown
-
2007
- 2007-08-31 ZA ZA200707520A patent/ZA200707520B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AR052370A1 (es) | 2007-03-14 |
JP2008529985A (ja) | 2008-08-07 |
UY29358A1 (es) | 2006-07-31 |
BRPI0606140A2 (pt) | 2009-06-02 |
DE102005005395A1 (de) | 2006-08-10 |
TW200639155A (en) | 2006-11-16 |
DOP2006000024A (es) | 2006-08-15 |
US7511059B2 (en) | 2009-03-31 |
PE20061085A1 (es) | 2006-11-11 |
CA2596967A1 (en) | 2006-08-10 |
EP1844027A1 (de) | 2007-10-17 |
CN101155791A (zh) | 2008-04-02 |
WO2006082107A1 (de) | 2006-08-10 |
AU2006210153A1 (en) | 2006-08-10 |
PA8661701A1 (es) | 2006-12-07 |
GT200600039A (es) | 2006-09-06 |
US20060223833A1 (en) | 2006-10-05 |
MX2007009387A (es) | 2007-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI370127B (en) | Pyrazolylaminopyridine derivatives useful as kinase inhibitors | |
HK1114380A1 (en) | Pyrrolopyrazoles as kinase inhibitors | |
IL186845A0 (en) | Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors | |
ZA200707520B (en) | Thiazolidnones for use as inhibitors of Polo-like kinase (Plk) | |
ZA201002543B (en) | Polo-like kinase inhibitors | |
PL1910348T3 (pl) | Związki benzotiazolowe i azabenzotiazolowe użyteczne jako inhibitory kinazy | |
HRP20130796T1 (en) | Pyrimidine derivatives used as pi-3 kinase inhibitors | |
IL177278A0 (en) | Pyrazolotriazines as kinase inhibitors | |
IL190078A0 (en) | Kinase inhibitors | |
AP2470A (en) | Novel phenylaminopyrimidine derivatives as inhibitors of BCR-ABL kinase | |
EP1954277A4 (en) | AMINOPYRIMIDINES SUITABLE AS KINASEINHIBITORS | |
EP2046333A4 (en) | THIOZOLIDINEDIONE DERIVATIVES AS INHIBITORS OF P13-KINASE | |
EP1778693A4 (en) | AS KINASEINHIBITORS USEFUL COMPOUNDS OF TRICYCLIC HETEROARYL | |
PL1943243T3 (pl) | Inhibitory kinazy | |
ZA200709732B (en) | Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors | |
IL185023A0 (en) | Thiazolidinones for use as inhibitors of polo-like kinase (plk) | |
ZA200804599B (en) | Aminopyrimidines useful as kinase inhibitors | |
EP1940411A4 (en) | MACROHETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | |
ZA200706212B (en) | Pyrazolylaminopyridine derivatives useful as kinase inhibitors | |
IL189985A0 (en) | Kinase inhibitors | |
ZA200803287B (en) | Kinase inhibitors |