ZA200700477B - 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri(hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors - Google Patents

1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri(hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors

Info

Publication number
ZA200700477B
ZA200700477B ZA200700477A ZA200700477A ZA200700477B ZA 200700477 B ZA200700477 B ZA 200700477B ZA 200700477 A ZA200700477 A ZA 200700477A ZA 200700477 A ZA200700477 A ZA 200700477A ZA 200700477 B ZA200700477 B ZA 200700477B
Authority
ZA
South Africa
Prior art keywords
hetero
heterocyclylethanes
arylethanes
tetra
tri
Prior art date
Application number
ZA200700477A
Inventor
Mark T Bilodeau
Wu Zhicai
Hartnett John
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA200700477B publication Critical patent/ZA200700477B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200700477A 2004-07-29 2007-01-16 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri(hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors ZA200700477B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59218104P 2004-07-29 2004-07-29

Publications (1)

Publication Number Publication Date
ZA200700477B true ZA200700477B (en) 2009-08-26

Family

ID=35613661

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200700477A ZA200700477B (en) 2004-07-29 2007-01-16 1,1,2,2-tetra (hetero) arylethanes or 1,1,2-tri(hetero) aryl-2-heterocyclylethanes as potassium channel inhibitors

Country Status (15)

Country Link
KR (1) KR20070043985A (en)
AR (1) AR049847A1 (en)
BR (1) BRPI0513793A (en)
CR (1) CR8876A (en)
EC (1) ECSP077208A (en)
IL (1) IL180846A0 (en)
MA (1) MA28980B1 (en)
MX (1) MX2007001188A (en)
NO (1) NO20071107L (en)
PE (1) PE20060382A1 (en)
RU (1) RU2344134C2 (en)
TW (1) TW200607493A (en)
UA (1) UA88018C2 (en)
WO (1) WO2006028590A1 (en)
ZA (1) ZA200700477B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120029447A1 (en) * 2009-03-18 2012-02-02 Medicure International Inc. Transdermal pharmaceutical preparation and administration of tirofiban
MY169219A (en) 2012-06-11 2019-03-19 Bristol Myers Squibb Co Phosphoramidic acid prodrugs of 5 - [5 - phenyl- 4 - (pyridin- 2 - ylmethylamino) quinazolin- 2 - yl] pyridine- 3 ? sulfonamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE400551T1 (en) * 2002-01-04 2008-07-15 Neurosearch As POTASSIUM CHANNEL MODULATORS

Also Published As

Publication number Publication date
MX2007001188A (en) 2007-03-21
AR049847A1 (en) 2006-09-06
NO20071107L (en) 2007-04-19
BRPI0513793A (en) 2008-05-13
RU2007107408A (en) 2008-09-10
WO2006028590A1 (en) 2006-03-16
RU2344134C2 (en) 2009-01-20
MA28980B1 (en) 2007-11-01
KR20070043985A (en) 2007-04-26
UA88018C2 (en) 2009-09-10
CR8876A (en) 2007-08-28
PE20060382A1 (en) 2006-05-15
TW200607493A (en) 2006-03-01
ECSP077208A (en) 2007-02-28
IL180846A0 (en) 2007-06-03

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