ZA200610168B - Compositions comprising flavonoids and tocotrienols and methods thereof - Google Patents

Compositions comprising flavonoids and tocotrienols and methods thereof Download PDF

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Publication number
ZA200610168B
ZA200610168B ZA200610168A ZA200610168A ZA200610168B ZA 200610168 B ZA200610168 B ZA 200610168B ZA 200610168 A ZA200610168 A ZA 200610168A ZA 200610168 A ZA200610168 A ZA 200610168A ZA 200610168 B ZA200610168 B ZA 200610168B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical formulation
formulation according
pharmaceutical
lowers
administration
Prior art date
Application number
ZA200610168A
Other languages
English (en)
Inventor
Guthrie Najla
Original Assignee
Kgk Synergize Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kgk Synergize Inc filed Critical Kgk Synergize Inc
Publication of ZA200610168B publication Critical patent/ZA200610168B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA200610168A 2004-05-26 2005-05-24 Compositions comprising flavonoids and tocotrienols and methods thereof ZA200610168B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57449004P 2004-05-26 2004-05-26

Publications (1)

Publication Number Publication Date
ZA200610168B true ZA200610168B (en) 2008-06-25

Family

ID=35450644

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200610168A ZA200610168B (en) 2004-05-26 2005-05-24 Compositions comprising flavonoids and tocotrienols and methods thereof

Country Status (11)

Country Link
US (2) US20060013901A1 (de)
EP (1) EP1748774B1 (de)
KR (1) KR20070088325A (de)
CN (1) CN101001624A (de)
AT (1) ATE491447T1 (de)
AU (1) AU2005247162A1 (de)
CA (1) CA2567969A1 (de)
DE (1) DE602005025339D1 (de)
IL (1) IL179544A0 (de)
WO (1) WO2005115378A1 (de)
ZA (1) ZA200610168B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005247159B2 (en) * 2004-05-26 2015-07-23 Interhealth Nutraceuticals Incorporated Pharmaceutical products for treating neoplastic disease and inflammation
WO2005115377A1 (en) * 2004-05-26 2005-12-08 Kgk Synergize Inc Functional foods comprising flavonoids and tocotrienols and methods thereof
US20080166418A1 (en) * 2007-01-04 2008-07-10 Sones Scott F Krill oil compositions
JP2008247826A (ja) * 2007-03-30 2008-10-16 Hiroshima Univ 血糖値調整剤およびまたは血中コレステロール値調整剤
EP2170331B1 (de) * 2007-06-29 2014-12-03 Laboratoires Dr Ng Payot Synergistische kombination von proanthoyanidinen, gamma-tocotrienol und niacin
KR101747125B1 (ko) * 2012-10-12 2017-06-14 고쿠리츠다이가쿠호진 류큐다이가쿠 감귤류 유래의 노비레틴 및 탄게레틴 함유물의 제조 방법 및 그 방법으로 얻은 노비레틴 및 탄게레틴 함유물
NZ628963A (en) * 2012-11-13 2017-02-24 Gordagen Pharmaceuticals Pty Ltd Transmucosal delivery of tocotrienol
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603142A (en) * 1984-06-01 1986-07-29 Wisconsin Alumni Research Foundation Cholesterol lowering method of use
US5217992A (en) * 1989-10-04 1993-06-08 Bristol-Myers Squibb Company Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
KR20000075919A (ko) * 1997-03-04 2000-12-26 리차드 에이취 리저 이소프레노이드와 스타틴의 배합물로 종양 성장을 억제하는 방법
US6239114B1 (en) * 1997-09-26 2001-05-29 Kgk Synergize Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
US6251400B1 (en) * 1997-09-26 2001-06-26 Kgk Synergize Inc Compositions and methods of treatment of neoplastic diseases and hypercholesterolemia with citrus limonoids and flavonoids and tocotrienols
US20010055627A1 (en) * 1997-09-26 2001-12-27 Najla Guthrie Compositions And Methods For Regulating Lipoproteins And Hypercholesterolemia With Limonoids, Flavonoids And Tocotrienols
KR20000019716A (ko) * 1998-09-15 2000-04-15 박호군 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물
US6987125B1 (en) * 1998-10-06 2006-01-17 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones
CA2375633C (en) * 1999-06-01 2014-03-18 Ocean Spray Cranberries, Inc. Cranberry seed oil extract and compositions containing components thereof
US20020006953A1 (en) * 1999-11-05 2002-01-17 Carla R. McGill Modification of cholesterol concentrations with citus phytochemicals
CA2403548A1 (en) * 2000-03-17 2001-09-27 United States Department Of Agriculture Compositions and methods of treating, reducing, and preventing cardiovascular diseases and disorders with polymethoxyflavones
AU2001251610A1 (en) * 2000-04-13 2001-11-07 Ocean Spray Cranberries, Inc. Novel compositions derived from cranberry and grapefruit and therapeutic uses therefor
US6579544B1 (en) * 2000-05-31 2003-06-17 Nutriex, L.L.C. Method for supplementing the diet
US20020090405A1 (en) * 2000-09-15 2002-07-11 Najla Guthrie Components of canola for the treatment of cancer
US20020090404A1 (en) * 2000-09-15 2002-07-11 Najla Guthrie Components of canola for treating hyperlipidemia
GB0026018D0 (en) * 2000-10-24 2000-12-13 Novartis Nutrition Ag New composition
WO2002055071A1 (en) * 2001-01-15 2002-07-18 Kgk Synergize Compositions and methods for regulating lipoproteins and hypercholesterolmia with limonoids flavonoids and tocotrienols
MXPA03010080A (es) * 2001-05-02 2006-04-05 Kgk Synergize Inc Uso de flavonas polimetoxiladas para tratar la resistencia a la insulina.
US7074825B2 (en) * 2002-03-07 2006-07-11 Huanbiao Mo Composition and method for treating cancer
EP1415549A1 (de) * 2002-11-01 2004-05-06 Galileo Laboratories, Inc. Synergistische Antioxidantien-Kombination aus Tocolen und Polyphenolen
US20050227930A1 (en) * 2004-04-08 2005-10-13 Kgk Synergize Inc. Cholesterol lowering combination
AU2005247159B2 (en) * 2004-05-26 2015-07-23 Interhealth Nutraceuticals Incorporated Pharmaceutical products for treating neoplastic disease and inflammation

Also Published As

Publication number Publication date
CA2567969A1 (en) 2005-12-08
EP1748774A4 (de) 2007-12-19
DE602005025339D1 (de) 2011-01-27
CN101001624A (zh) 2007-07-18
EP1748774A1 (de) 2007-02-07
US20060013901A1 (en) 2006-01-19
WO2005115378B1 (en) 2006-02-16
IL179544A0 (en) 2007-07-04
KR20070088325A (ko) 2007-08-29
US20090156665A1 (en) 2009-06-18
ATE491447T1 (de) 2011-01-15
AU2005247162A1 (en) 2005-12-08
EP1748774B1 (de) 2010-12-15
WO2005115378A1 (en) 2005-12-08

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