ZA200606526B - Multiparticulate O-desmethylvenlafaxine salts and uses thereof - Google Patents

Multiparticulate O-desmethylvenlafaxine salts and uses thereof

Info

Publication number
ZA200606526B
ZA200606526B ZA200606526A ZA200606526A ZA200606526B ZA 200606526 B ZA200606526 B ZA 200606526B ZA 200606526 A ZA200606526 A ZA 200606526A ZA 200606526 A ZA200606526 A ZA 200606526A ZA 200606526 B ZA200606526 B ZA 200606526B
Authority
ZA
South Africa
Prior art keywords
multiparticulate
desmethylvenlafaxine salts
desmethylvenlafaxine
salts
Prior art date
Application number
ZA200606526A
Other languages
English (en)
Inventor
Christopher Richard Diorio
Mahdi B Fawzi
Syed M Shah
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA200606526B publication Critical patent/ZA200606526B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200606526A 2004-02-06 2006-08-04 Multiparticulate O-desmethylvenlafaxine salts and uses thereof ZA200606526B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54238404P 2004-02-06 2004-02-06

Publications (1)

Publication Number Publication Date
ZA200606526B true ZA200606526B (en) 2010-03-31

Family

ID=34860300

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200606526A ZA200606526B (en) 2004-02-06 2006-08-04 Multiparticulate O-desmethylvenlafaxine salts and uses thereof

Country Status (21)

Country Link
US (1) US20050175698A1 (fr)
EP (2) EP1711167A1 (fr)
JP (1) JP2007520553A (fr)
KR (1) KR20060132891A (fr)
CN (1) CN1917860A (fr)
AR (1) AR050230A1 (fr)
AU (1) AU2005212166A1 (fr)
BR (1) BRPI0507372A (fr)
CA (1) CA2554559A1 (fr)
CR (1) CR8535A (fr)
EC (1) ECSP066827A (fr)
IL (1) IL177052A0 (fr)
NO (1) NO20063963L (fr)
PA (1) PA8622601A1 (fr)
PE (1) PE20050771A1 (fr)
RU (1) RU2006127437A (fr)
SG (1) SG149894A1 (fr)
SV (1) SV2005002008A (fr)
TW (1) TW200528092A (fr)
WO (1) WO2005077340A1 (fr)
ZA (1) ZA200606526B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
CA2368083A1 (fr) * 1999-04-06 2000-10-12 Sepracor Inc. Derives de la venlafaxine et leurs procedes de preparation et utilisation
DK1360169T3 (da) 2001-02-12 2007-11-26 Wyeth Corp Succinatsalt af O-desmethyl-venlafaxin
EP1832288B1 (fr) * 2004-12-27 2012-06-20 Astellas Pharma Inc. Préparation pharmaceutique granulaire stable de solifénacine ou de son sel
BRPI0608754A2 (pt) * 2005-03-31 2010-01-26 Wyeth Corp Produto combinado, comprimido, cápsula, usos de um produto combinado, e de um composto
CN101257898A (zh) * 2005-07-06 2008-09-03 塞普拉科公司 艾司佐匹克隆与o-去甲基文拉法辛的组合以及治疗绝经期和心境障碍、焦虑症和认知障碍的方法
WO2007011619A2 (fr) * 2005-07-15 2007-01-25 Wyeth Formes pharmaceutiques orales hautement biodisponibles a liberation retardee, de o-desmethylvenlafaxine succinate
US7595340B2 (en) 2005-07-15 2009-09-29 Wyeth Serotonin and norepinephrine reuptake inhibitor and uses thereof
CA2615362A1 (fr) * 2005-07-15 2007-01-25 Wyeth Inhibiteur double hautement selectif de recaptage de la serotonine et de la noradrenaline et son utilisation
US7687520B2 (en) 2005-07-15 2010-03-30 Wyeth Llc Serotonin and norepinephrine reuptake inhibitors and uses thereof
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
EP1870395A1 (fr) 2006-06-19 2007-12-26 KRKA, D.D., Novo Mesto Procédé pour fabriquer de l'o-Desmethylvenlafaxine et de ses analogues
CA2692738A1 (fr) * 2007-07-12 2009-01-15 Dr. Reddy's Laboratories, Ltd. O-desmethylvenlafaxine
WO2009049354A1 (fr) * 2007-10-16 2009-04-23 Alphapharm Pty Ltd Formulation pharmaceutique à libération contrôlée
WO2009053840A2 (fr) * 2007-10-22 2009-04-30 Actavis Group Ptc Ehf Formes solides de sels de (±)-o-déméthylvenlafaxine
WO2011121475A2 (fr) 2010-03-31 2011-10-06 Wockhardt Limited Forme pharmaceutique à libération modifiée comprenant de la desvenlafaxine ou des sels de celle-ci
MX2013011884A (es) 2011-04-12 2013-11-21 Lupin Ltd Composiciones farmaceuticas de liberacion modificada de desvenlafaxina.
US20150086628A1 (en) * 2012-05-03 2015-03-26 Cipla Limited Antiretroviral composition

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081496A (en) * 1959-10-15 1963-03-19 John F Moore Method of forming flexible sheets of cured foamed rubber
AT294000B (de) * 1965-01-11 1971-11-10 Diersch & Schroeder Verfahren zur Herstellung von Teppichen oder Läufern
US3885257A (en) * 1972-10-30 1975-05-27 Evans Ronald J P Pressure controlled resilient supporting structure
US4535186A (en) 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4603445A (en) * 1983-09-09 1986-08-05 Span-America Medical Systems, Inc. Support pad and method of manufacture
US5099627A (en) * 1990-09-28 1992-03-31 Benjamin Obdyke Incorporated Ventilated roof construction and method
US5203703A (en) * 1991-08-27 1993-04-20 Schneiderman Marc J Deglutition training method and apparatus
US7048906B2 (en) * 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6274171B1 (en) 1996-03-25 2001-08-14 American Home Products Corporation Extended release formulation of venlafaxine hydrochloride
US6162309A (en) * 1998-04-21 2000-12-19 Burlington Industries, Inc. Reinforced foam backed carpet
US6342533B1 (en) * 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
US6197828B1 (en) 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
CA2368083A1 (fr) * 1999-04-06 2000-10-12 Sepracor Inc. Derives de la venlafaxine et leurs procedes de preparation et utilisation
AU5738700A (en) * 1999-06-15 2001-01-02 American Home Products Corporation Enantiomers of o-desmethyl venlafaxine
US6863972B2 (en) * 2001-01-09 2005-03-08 Crane Plastics Company Llc Synthetic wood component having a foamed polymer backing
DK1360169T3 (da) * 2001-02-12 2007-11-26 Wyeth Corp Succinatsalt af O-desmethyl-venlafaxin
US20030152741A1 (en) * 2002-02-05 2003-08-14 Robbins Jeffrey L. Patterned polyurethane foam and a process for the production of tufted goods with patterned foam backing
AU2003226752A1 (en) * 2002-03-28 2003-10-13 Synthon B.V. Venlafaxine base
MXPA04012347A (es) * 2002-06-10 2005-02-25 Wyeth Corp Nueva sal formiato de o-desmetilvenlafaxina.
JP2004359665A (ja) * 2003-05-30 2004-12-24 Rohm & Haas Co 生体利用性増強剤を含有する治療組成物

Also Published As

Publication number Publication date
AU2005212166A1 (en) 2005-08-25
CN1917860A (zh) 2007-02-21
ECSP066827A (es) 2006-11-24
WO2005077340A1 (fr) 2005-08-25
SG149894A1 (en) 2009-02-27
RU2006127437A (ru) 2008-03-20
SV2005002008A (es) 2005-11-04
TW200528092A (en) 2005-09-01
CA2554559A1 (fr) 2005-08-25
PA8622601A1 (es) 2005-10-28
KR20060132891A (ko) 2006-12-22
EP2052717A1 (fr) 2009-04-29
PE20050771A1 (es) 2005-11-15
EP1711167A1 (fr) 2006-10-18
US20050175698A1 (en) 2005-08-11
IL177052A0 (en) 2006-12-10
AR050230A1 (es) 2006-10-11
BRPI0507372A (pt) 2007-07-10
JP2007520553A (ja) 2007-07-26
NO20063963L (no) 2006-09-05
CR8535A (es) 2006-12-07

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