ZA200601721B - 2-alkylidene-19-nor-vitamin D derivatives for the treatment of frailty, muscle damage or sarcopenia - Google Patents
2-alkylidene-19-nor-vitamin D derivatives for the treatment of frailty, muscle damage or sarcopenia Download PDFInfo
- Publication number
- ZA200601721B ZA200601721B ZA200601721A ZA200601721A ZA200601721B ZA 200601721 B ZA200601721 B ZA 200601721B ZA 200601721 A ZA200601721 A ZA 200601721A ZA 200601721 A ZA200601721 A ZA 200601721A ZA 200601721 B ZA200601721 B ZA 200601721B
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- ZA
- South Africa
- Prior art keywords
- vitamin
- methylene
- compounds
- group
- hydroxy
- Prior art date
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- 208000001076 sarcopenia Diseases 0.000 title claims description 19
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- QHUNJMXHQHHWQP-UHFFFAOYSA-N trimethylsilyl acetate Chemical compound CC(=O)O[Si](C)(C)C QHUNJMXHQHHWQP-UHFFFAOYSA-N 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 229960000281 trometamol Drugs 0.000 description 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 description 1
- 235000005282 vitamin D3 Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50450903P | 2003-09-19 | 2003-09-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200601721B true ZA200601721B (en) | 2007-07-25 |
Family
ID=34375511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200601721A ZA200601721B (en) | 2003-09-19 | 2006-02-27 | 2-alkylidene-19-nor-vitamin D derivatives for the treatment of frailty, muscle damage or sarcopenia |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20050065129A1 (ja) |
| EP (1) | EP1667688A1 (ja) |
| JP (1) | JP2007505882A (ja) |
| KR (1) | KR20060040744A (ja) |
| CN (1) | CN1852718A (ja) |
| AU (1) | AU2004273659A1 (ja) |
| BR (1) | BRPI0414564A (ja) |
| CA (1) | CA2538993A1 (ja) |
| IL (1) | IL174043A0 (ja) |
| MX (1) | MXPA06002947A (ja) |
| NO (1) | NO20061704L (ja) |
| NZ (1) | NZ545632A (ja) |
| RU (1) | RU2326674C2 (ja) |
| TW (1) | TW200512183A (ja) |
| WO (1) | WO2005027914A1 (ja) |
| ZA (1) | ZA200601721B (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150157648A1 (en) * | 2012-06-26 | 2015-06-11 | Entia Biosciences, Inc. | Nutritional approach to improving athletic performance and reducing injury with l-ergothioneine and/or vitamin d2 |
| EP2866811A1 (en) * | 2012-06-29 | 2015-05-06 | Wisconsin Alumni Research Foundation | USE OF 2-METHYLENE-19-NOR-(20S)-1 alpha,25-DIHYDROXYVITAMIN D³ TO TREAT SECONDARY HYPERPARATHYROIDISM |
| CN106489971A (zh) * | 2015-09-07 | 2017-03-15 | 江苏龙灯化学有限公司 | 一种除草组合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086191A (en) * | 1991-05-28 | 1992-02-04 | Wisconsin Alumni Research Foundation | Intermediates for the synthesis of 19-nor vitamin D compounds |
| DE69400495T2 (de) * | 1993-04-05 | 1997-04-30 | Wisconsin Alumni Res Found | 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle |
| US5843928A (en) * | 1997-03-17 | 1998-12-01 | Wisconsin Alumni Research Foundation | 2-alkylidene-19-nor-vitamin D compounds |
| IL152942A (en) * | 2000-05-31 | 2007-09-20 | Wisconsin Alumni Res Found | Compounds 2 - Ethyl and 2 - Ethylaidine - 19 - Nur - Vitamin D and pharmaceutical preparations containing them |
| US20030195175A1 (en) * | 2002-03-25 | 2003-10-16 | Deluca Hector F. | Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone |
-
2004
- 2004-09-06 CN CNA200480027153XA patent/CN1852718A/zh active Pending
- 2004-09-06 WO PCT/IB2004/002901 patent/WO2005027914A1/en active Application Filing
- 2004-09-06 RU RU2006107649/14A patent/RU2326674C2/ru not_active IP Right Cessation
- 2004-09-06 MX MXPA06002947A patent/MXPA06002947A/es not_active Application Discontinuation
- 2004-09-06 AU AU2004273659A patent/AU2004273659A1/en not_active Abandoned
- 2004-09-06 CA CA002538993A patent/CA2538993A1/en not_active Abandoned
- 2004-09-06 KR KR1020067005410A patent/KR20060040744A/ko not_active Application Discontinuation
- 2004-09-06 JP JP2006526714A patent/JP2007505882A/ja active Pending
- 2004-09-06 EP EP04769300A patent/EP1667688A1/en not_active Withdrawn
- 2004-09-06 NZ NZ545632A patent/NZ545632A/en unknown
- 2004-09-06 BR BRPI0414564-0A patent/BRPI0414564A/pt not_active IP Right Cessation
- 2004-09-15 TW TW093127919A patent/TW200512183A/zh unknown
- 2004-09-16 US US10/943,553 patent/US20050065129A1/en not_active Abandoned
-
2006
- 2006-02-27 ZA ZA200601721A patent/ZA200601721B/en unknown
- 2006-03-01 IL IL174043A patent/IL174043A0/en unknown
- 2006-04-18 NO NO20061704A patent/NO20061704L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005027914A1 (en) | 2005-03-31 |
| AU2004273659A1 (en) | 2005-03-31 |
| US20050065129A1 (en) | 2005-03-24 |
| TW200512183A (en) | 2005-04-01 |
| NO20061704L (no) | 2006-06-19 |
| CA2538993A1 (en) | 2005-03-31 |
| EP1667688A1 (en) | 2006-06-14 |
| NZ545632A (en) | 2009-09-25 |
| CN1852718A (zh) | 2006-10-25 |
| KR20060040744A (ko) | 2006-05-10 |
| RU2006107649A (ru) | 2007-11-10 |
| IL174043A0 (en) | 2006-08-01 |
| MXPA06002947A (es) | 2006-05-31 |
| RU2326674C2 (ru) | 2008-06-20 |
| BRPI0414564A (pt) | 2006-11-07 |
| JP2007505882A (ja) | 2007-03-15 |
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