ZA200510150B - Process for manufacture of nematode-extracted anticoagulant protein (NAP) - Google Patents

Process for manufacture of nematode-extracted anticoagulant protein (NAP)

Info

Publication number
ZA200510150B
ZA200510150B ZA200510150A ZA200510150A ZA200510150B ZA 200510150 B ZA200510150 B ZA 200510150B ZA 200510150 A ZA200510150 A ZA 200510150A ZA 200510150 A ZA200510150 A ZA 200510150A ZA 200510150 B ZA200510150 B ZA 200510150B
Authority
ZA
South Africa
Prior art keywords
nap
nematode
manufacture
anticoagulant protein
extracted anticoagulant
Prior art date
Application number
ZA200510150A
Other languages
English (en)
Inventor
Christine B Mendoza
Moss David
Lidell John
Original Assignee
Dendreon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dendreon Corp filed Critical Dendreon Corp
Publication of ZA200510150B publication Critical patent/ZA200510150B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200510150A 2003-05-15 2005-12-13 Process for manufacture of nematode-extracted anticoagulant protein (NAP) ZA200510150B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/440,475 US20040229334A1 (en) 2003-05-15 2003-05-15 Process for manufacture of nematode-extracted anticoagulant protein (NAP)

Publications (1)

Publication Number Publication Date
ZA200510150B true ZA200510150B (en) 2007-03-28

Family

ID=33418007

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200510150A ZA200510150B (en) 2003-05-15 2005-12-13 Process for manufacture of nematode-extracted anticoagulant protein (NAP)

Country Status (10)

Country Link
US (3) US20040229334A1 (es)
EP (1) EP1623038A4 (es)
JP (1) JP2007503216A (es)
CN (1) CN100591774C (es)
AU (1) AU2004240623B2 (es)
CA (1) CA2525831A1 (es)
MX (1) MXPA05012298A (es)
RU (1) RU2355770C2 (es)
WO (1) WO2004103292A2 (es)
ZA (1) ZA200510150B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102631328A (zh) * 2012-05-04 2012-08-15 常州千红生化制药股份有限公司 重组人抗血栓蛋白冻干粉针剂及其制备方法
WO2017044530A1 (en) * 2015-09-08 2017-03-16 Waters Technologies Corporation Multidimensional chromatoggraphy method for analysis of antibody-drug conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
HU225126B1 (en) * 1994-10-18 2006-06-28 Dendreon Corp Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
EP0880969A1 (en) * 1997-05-28 1998-12-02 Applied Research Systems ARS Holdings N.V. Pharmaceutical compositions of peptides having low solubility in physiological medium
EP1184393A1 (en) * 2000-09-04 2002-03-06 Debiopharm S.A. Process for the purification of EPI-HNE proteins
US6543629B1 (en) * 2001-09-24 2003-04-08 Ex-Cell Home Fashions, Inc. Decorative curtain rod end cover
US7132398B2 (en) * 2003-05-06 2006-11-07 Dendreon Corporation Method of treatment of hemorrhagic disease using a factor VIIa/tissue factor inhibitor

Also Published As

Publication number Publication date
US20080221026A1 (en) 2008-09-11
AU2004240623A1 (en) 2004-12-02
JP2007503216A (ja) 2007-02-22
CN100591774C (zh) 2010-02-24
US20060211086A1 (en) 2006-09-21
AU2004240623B2 (en) 2010-07-15
US20040229334A1 (en) 2004-11-18
CA2525831A1 (en) 2004-12-02
MXPA05012298A (es) 2006-05-25
RU2005139130A (ru) 2006-06-10
CN1823169A (zh) 2006-08-23
US7279309B2 (en) 2007-10-09
EP1623038A4 (en) 2006-07-19
RU2355770C2 (ru) 2009-05-20
WO2004103292A2 (en) 2004-12-02
WO2004103292A3 (en) 2005-09-29
EP1623038A2 (en) 2006-02-08

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