ZA200508300B - RAGE antagonists as agents to reverse amyloidosis and diseases associated therewith - Google Patents

RAGE antagonists as agents to reverse amyloidosis and diseases associated therewith

Info

Publication number
ZA200508300B
ZA200508300B ZA200508300A ZA200508300A ZA200508300B ZA 200508300 B ZA200508300 B ZA 200508300B ZA 200508300 A ZA200508300 A ZA 200508300A ZA 200508300 A ZA200508300 A ZA 200508300A ZA 200508300 B ZA200508300 B ZA 200508300B
Authority
ZA
South Africa
Prior art keywords
agents
associated therewith
diseases associated
rage antagonists
amyloidosis
Prior art date
Application number
ZA200508300A
Other languages
English (en)
Inventor
Adnan M M Mjalli
Robert C Andrews
Jane M Shen
Rothlein Robert
Original Assignee
Transtech Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transtech Pharma Inc filed Critical Transtech Pharma Inc
Publication of ZA200508300B publication Critical patent/ZA200508300B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200508300A 2003-05-20 2004-05-20 RAGE antagonists as agents to reverse amyloidosis and diseases associated therewith ZA200508300B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47196903P 2003-05-20 2003-05-20

Publications (1)

Publication Number Publication Date
ZA200508300B true ZA200508300B (en) 2007-03-28

Family

ID=33551437

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200508300A ZA200508300B (en) 2003-05-20 2004-05-20 RAGE antagonists as agents to reverse amyloidosis and diseases associated therewith

Country Status (10)

Country Link
US (2) US20050026811A1 (https=)
EP (1) EP1635823A1 (https=)
JP (1) JP2007503469A (https=)
CN (1) CN1805743A (https=)
AU (1) AU2004251599A1 (https=)
BR (1) BRPI0410436A (https=)
CA (1) CA2522275A1 (https=)
MX (1) MXPA05012350A (https=)
WO (1) WO2005000295A1 (https=)
ZA (1) ZA200508300B (https=)

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Also Published As

Publication number Publication date
AU2004251599A1 (en) 2005-01-06
CA2522275A1 (en) 2005-01-06
US20050026811A1 (en) 2005-02-03
MXPA05012350A (es) 2006-05-25
BRPI0410436A (pt) 2006-05-30
EP1635823A1 (en) 2006-03-22
WO2005000295A1 (en) 2005-01-06
US20090035302A1 (en) 2009-02-05
JP2007503469A (ja) 2007-02-22
CN1805743A (zh) 2006-07-19

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