ZA200506548B - Vaccines derived from epithelial cell mucin MUC-1 - Google Patents
Vaccines derived from epithelial cell mucin MUC-1 Download PDFInfo
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- ZA200506548B ZA200506548B ZA200506548A ZA200506548A ZA200506548B ZA 200506548 B ZA200506548 B ZA 200506548B ZA 200506548 A ZA200506548 A ZA 200506548A ZA 200506548 A ZA200506548 A ZA 200506548A ZA 200506548 B ZA200506548 B ZA 200506548B
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- nucleic acid
- composition
- muc
- sequence
- plasmid
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- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000010474 transient expression Effects 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000003656 tris buffered saline Substances 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 229950009795 tucaresol Drugs 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 229960004295 valine Drugs 0.000 description 1
- 235000014393 valine Nutrition 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 229960004854 viral vaccine Drugs 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4727—Mucins, e.g. human intestinal mucin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0304634.9A GB0304634D0 (en) | 2003-02-28 | 2003-02-28 | Vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200506548B true ZA200506548B (en) | 2007-12-27 |
Family
ID=9953871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200506548A ZA200506548B (en) | 2003-02-28 | 2005-08-16 | Vaccines derived from epithelial cell mucin MUC-1 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060147458A1 (ko) |
| EP (1) | EP1597368A2 (ko) |
| JP (1) | JP2007524352A (ko) |
| KR (1) | KR20050107472A (ko) |
| CN (1) | CN1753994A (ko) |
| AU (1) | AU2004215187A1 (ko) |
| BR (1) | BRPI0407601A (ko) |
| CA (1) | CA2517062A1 (ko) |
| CO (1) | CO5670372A2 (ko) |
| GB (1) | GB0304634D0 (ko) |
| IS (1) | IS7956A (ko) |
| MA (1) | MA27746A1 (ko) |
| MX (1) | MXPA05009160A (ko) |
| NO (1) | NO20054102L (ko) |
| PL (1) | PL378761A1 (ko) |
| RU (1) | RU2005125608A (ko) |
| WO (1) | WO2004076665A2 (ko) |
| ZA (1) | ZA200506548B (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0617387D0 (en) * | 2006-09-04 | 2006-10-11 | Glaxo Group Ltd | Synthetic gene |
| CN103570821A (zh) * | 2012-07-27 | 2014-02-12 | 北京智飞绿竹生物制药有限公司 | 粘蛋白-1抗原性多肽及其作为肿瘤疫苗的用途 |
| CA3036799A1 (en) | 2016-09-28 | 2018-04-05 | Bavarian Nordic A/S | Compositions and methods for enhancing the stability of transgenes in poxviruses |
| CN114230655A (zh) * | 2021-03-24 | 2022-03-25 | 深圳市新靶向生物科技有限公司 | 一种与食道癌驱动基因突变相关的抗原肽组合及其应用 |
| WO2023122526A1 (en) * | 2021-12-20 | 2023-06-29 | Zoetis Services Llc | Use of interferon as an adjuvant in vaccines |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPM322393A0 (en) * | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| US6548643B1 (en) * | 1994-11-16 | 2003-04-15 | Austin Research Institute | Antigen carbohydrate compounds and their use in immunotherapy |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
| DE60030450T2 (de) * | 1999-09-08 | 2007-08-30 | Transgene S.A. | Von MUC-1 abgeleitete Peptide |
| GB9930359D0 (en) * | 1999-12-22 | 2000-02-09 | Glaxo Group Ltd | Novel polypeptides |
| WO2001057068A1 (en) * | 2000-02-01 | 2001-08-09 | The Austin Research Institute | Mucin-1 derived antigens and their use in immunotherapy |
| GB0212046D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| GB0212036D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| GB0321614D0 (en) * | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Vaccines |
-
2003
- 2003-02-28 GB GBGB0304634.9A patent/GB0304634D0/en not_active Ceased
-
2004
- 2004-02-26 US US10/547,207 patent/US20060147458A1/en not_active Abandoned
- 2004-02-26 RU RU2005125608/13A patent/RU2005125608A/ru not_active Application Discontinuation
- 2004-02-26 CN CNA2004800052301A patent/CN1753994A/zh active Pending
- 2004-02-26 CA CA002517062A patent/CA2517062A1/en not_active Abandoned
- 2004-02-26 KR KR1020057016076A patent/KR20050107472A/ko not_active Application Discontinuation
- 2004-02-26 AU AU2004215187A patent/AU2004215187A1/en not_active Abandoned
- 2004-02-26 EP EP04714791A patent/EP1597368A2/en not_active Ceased
- 2004-02-26 PL PL378761A patent/PL378761A1/pl unknown
- 2004-02-26 WO PCT/EP2004/002007 patent/WO2004076665A2/en active Application Filing
- 2004-02-26 MX MXPA05009160A patent/MXPA05009160A/es unknown
- 2004-02-26 JP JP2006501975A patent/JP2007524352A/ja active Pending
- 2004-02-26 BR BRPI0407601-0A patent/BRPI0407601A/pt not_active IP Right Cessation
-
2005
- 2005-07-25 IS IS7956A patent/IS7956A/is unknown
- 2005-08-16 ZA ZA200506548A patent/ZA200506548B/en unknown
- 2005-08-24 CO CO05084394A patent/CO5670372A2/es not_active Application Discontinuation
- 2005-09-02 NO NO20054102A patent/NO20054102L/no not_active Application Discontinuation
- 2005-09-09 MA MA28489A patent/MA27746A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA27746A1 (fr) | 2006-02-01 |
| CN1753994A (zh) | 2006-03-29 |
| AU2004215187A1 (en) | 2004-09-10 |
| CO5670372A2 (es) | 2006-08-31 |
| GB0304634D0 (en) | 2003-04-02 |
| EP1597368A2 (en) | 2005-11-23 |
| BRPI0407601A (pt) | 2006-02-14 |
| KR20050107472A (ko) | 2005-11-11 |
| CA2517062A1 (en) | 2004-09-10 |
| NO20054102D0 (no) | 2005-09-02 |
| WO2004076665A2 (en) | 2004-09-10 |
| PL378761A1 (pl) | 2006-05-15 |
| RU2005125608A (ru) | 2006-03-27 |
| WO2004076665A3 (en) | 2005-02-24 |
| US20060147458A1 (en) | 2006-07-06 |
| JP2007524352A (ja) | 2007-08-30 |
| IS7956A (is) | 2005-07-25 |
| MXPA05009160A (es) | 2005-10-20 |
| NO20054102L (no) | 2005-09-27 |
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