ZA200503461B - Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof - Google Patents

Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof Download PDF

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Publication number
ZA200503461B
ZA200503461B ZA200503461A ZA200503461A ZA200503461B ZA 200503461 B ZA200503461 B ZA 200503461B ZA 200503461 A ZA200503461 A ZA 200503461A ZA 200503461 A ZA200503461 A ZA 200503461A ZA 200503461 B ZA200503461 B ZA 200503461B
Authority
ZA
South Africa
Prior art keywords
gel
biocompatible
cohesive biopolymer
biopolymer gel
dextran sulfate
Prior art date
Application number
ZA200503461A
Other languages
English (en)
Inventor
Nevo Zvi
Astachov Liliana
Rochkind Semion
Shahar Abraham
Original Assignee
Nvr Labs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nvr Labs Ltd filed Critical Nvr Labs Ltd
Publication of ZA200503461B publication Critical patent/ZA200503461B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02Dextran; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/32Materials or treatment for tissue regeneration for nerve reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Peptides Or Proteins (AREA)
ZA200503461A 2002-09-30 2005-04-29 Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof ZA200503461B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL15203002A IL152030A0 (en) 2002-09-30 2002-09-30 Cohesive biopolymers comprising sulfated polysaccharides and fibrillar proteins and use thereof for tissue repair

Publications (1)

Publication Number Publication Date
ZA200503461B true ZA200503461B (en) 2007-01-31

Family

ID=29765027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200503461A ZA200503461B (en) 2002-09-30 2005-04-29 Cohesive coprecipitates of sulfated polyasaccharide and fibrillar protein and use thereof

Country Status (8)

Country Link
US (1) US20060110426A1 (de)
EP (1) EP1549295A4 (de)
JP (1) JP2006506110A (de)
AU (1) AU2003269440A1 (de)
CA (1) CA2501009A1 (de)
IL (1) IL152030A0 (de)
WO (1) WO2004029095A2 (de)
ZA (1) ZA200503461B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005117912A1 (en) 2004-05-27 2005-12-15 Avigen, Inc. Methods for treating bleeding disorders using sulfated polysaccharides
AU2005286097A1 (en) * 2004-09-21 2006-03-30 Nvr Labs. Ltd. Compositions and methods for stem cell expansion and differentiation
FR2881434B1 (fr) * 2005-02-02 2007-05-11 Coletica Sa Dispositif de support de culture de cellules
CN100382772C (zh) * 2005-09-28 2008-04-23 南通大学 含蚕丝丝素的医用神经移植物的制备方法
EP2259803B2 (de) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Vorrichtung zur förderung von hämostase und/oder wundheilung
US8546096B2 (en) 2008-08-22 2013-10-01 Baxter International Inc. Method for identifying a non-anticoagulant sulfated polysaccharide which enhances blood coagulation dependence on FXI
DE102008059857A1 (de) * 2008-12-01 2010-06-02 Forschungsinstitut für Leder und Kunststoffbahnen gGmbH Mit Kohlenhydrat-Derivaten additivierte Gelatinezusammensetzungen
EP2384205A1 (de) * 2009-01-02 2011-11-09 Ramot at Tel-Aviv University Ltd. Fibrin- und fibrinogen-matrizen und ihre verwendung
EP2498830B1 (de) * 2009-11-11 2016-09-21 University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) Hydrogels auf Basis von Dextran-Hyaluronsäure
CA2786758A1 (en) 2010-01-14 2011-07-21 Baxter International Inc. Methods and compositions for treating bleeding disorders
CA2838793C (en) 2011-07-19 2019-08-06 Baxter International Inc. Resorption enhancers as additives to improve the oral formulation of non-anticoagulant sulfated polysaccharides
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
JP6394916B2 (ja) 2012-06-12 2018-09-26 フェロサン メディカル デバイシーズ エイ/エス 乾燥止血組成物
WO2014028382A1 (en) 2012-08-14 2014-02-20 Baxter International Inc. Methods and systems for screening compositions comprising non-anticoagulant sulfated polysaccharides
US9474767B2 (en) * 2012-11-12 2016-10-25 Warsaw Orthopedic, Inc. Compositions and methods for inhibiting bone growth
US9421221B2 (en) * 2012-11-12 2016-08-23 Warsaw Orthopedic, Inc. Compositions and methods for inhibiting adhesion formation
US9724078B2 (en) 2013-06-21 2017-08-08 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US9981067B2 (en) 2013-09-30 2018-05-29 Bioactive Regenerative Therapeutics, Inc. Biomimetic hybrid gel compositions and methods of use
CA2928963C (en) 2013-12-11 2020-10-27 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
JP6747650B2 (ja) 2014-12-24 2020-08-26 フェロサン メディカル デバイシーズ エイ/エス 第1の物質と第2の物質を保持し混合するためのシリンジ
BR112017027695A2 (pt) 2015-07-03 2018-09-04 Ferrosan Medical Devices As seringa para retenção e mistura de primeira e segunda substâncias
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352707B1 (en) * 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
US5571166A (en) * 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
US5783214A (en) * 1994-06-13 1998-07-21 Buford Biomedical, Inc. Bio-erodible matrix for the controlled release of medicinals
AU737348B2 (en) * 1994-08-12 2001-08-16 Meadox Medicals, Inc. Vascular graft impregnated with a heparin-containing collagen sealant
DE69524501T2 (de) * 1994-08-12 2002-05-29 Meadox Medicals, Inc. Mit einen Heparin enhaltendes Kollagendichtmittel imprägniertes Gefässtransplantat
WO1997041899A1 (en) * 1996-05-03 1997-11-13 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
AU2003215330B2 (en) * 2002-02-21 2008-03-13 Encelle, Inc. Immobilized bioactive hydrogel matrices as surface coatings

Also Published As

Publication number Publication date
IL152030A0 (en) 2003-05-29
CA2501009A1 (en) 2004-04-08
AU2003269440A1 (en) 2004-04-19
EP1549295A4 (de) 2007-08-15
WO2004029095A3 (en) 2004-06-03
US20060110426A1 (en) 2006-05-25
JP2006506110A (ja) 2006-02-23
EP1549295A2 (de) 2005-07-06
WO2004029095A2 (en) 2004-04-08

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