ZA200503201B - DNA vaccine encoding at least two nonstructural early proteins of papillomavirus - Google Patents

DNA vaccine encoding at least two nonstructural early proteins of papillomavirus Download PDF

Info

Publication number
ZA200503201B
ZA200503201B ZA200503201A ZA200503201A ZA200503201B ZA 200503201 B ZA200503201 B ZA 200503201B ZA 200503201 A ZA200503201 A ZA 200503201A ZA 200503201 A ZA200503201 A ZA 200503201A ZA 200503201 B ZA200503201 B ZA 200503201B
Authority
ZA
South Africa
Prior art keywords
hpv
polynucleotide
vector
pharmaceutical composition
polynucleotide sequence
Prior art date
Application number
ZA200503201A
Other languages
English (en)
Inventor
Gerald Wayne Gough
Christopher Michael Roberts
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA200503201B publication Critical patent/ZA200503201B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • C07K14/025Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200503201A 2002-10-03 2005-04-20 DNA vaccine encoding at least two nonstructural early proteins of papillomavirus ZA200503201B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0222953.2A GB0222953D0 (en) 2002-10-03 2002-10-03 Novel Compounds

Publications (1)

Publication Number Publication Date
ZA200503201B true ZA200503201B (en) 2006-06-28

Family

ID=9945247

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200503201A ZA200503201B (en) 2002-10-03 2005-04-20 DNA vaccine encoding at least two nonstructural early proteins of papillomavirus

Country Status (21)

Country Link
US (2) US20060165713A1 (https=)
EP (1) EP1546191A2 (https=)
JP (1) JP2006516386A (https=)
KR (1) KR20050050115A (https=)
CN (1) CN100393878C (https=)
AR (1) AR041515A1 (https=)
AU (1) AU2003294672A1 (https=)
BR (1) BR0314986A (https=)
CA (1) CA2500093A1 (https=)
CO (1) CO5580837A2 (https=)
GB (1) GB0222953D0 (https=)
IS (1) IS7775A (https=)
MA (1) MA27474A1 (https=)
MX (1) MXPA05003558A (https=)
NO (1) NO20051561L (https=)
NZ (1) NZ539154A (https=)
PL (1) PL376534A1 (https=)
RU (1) RU2354701C2 (https=)
TW (1) TW200411055A (https=)
WO (1) WO2004031222A2 (https=)
ZA (1) ZA200503201B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2241325E (pt) 2002-10-29 2012-04-12 Coley Pharm Gmbh Utilização de oligonucleótidos cpg no tratamento de infecção com vírus da hepatite c
WO2008092854A2 (en) * 2007-01-30 2008-08-07 Transgene S.A. Papillomavirus e2 polypeptide used for vaccination
GB0710538D0 (en) * 2007-06-01 2007-07-11 Glaxo Group Ltd Vaccine
CN102985109B (zh) * 2010-06-25 2016-05-11 瓦西博迪公司 同型二聚体蛋白质构建体
CN107001430A (zh) * 2014-10-24 2017-08-01 哈普威克斯有限责任公司 癌症和皮肤病变治疗
JP2019505512A (ja) 2016-01-08 2019-02-28 バッシボディ アクスイェ セルスカプ 治療用抗癌ネオエピトープワクチン
CA3023022A1 (en) * 2016-05-04 2017-11-09 Transgene Sa Combination therapy with cpg tlr9 ligand
CN117203342A (zh) * 2020-11-25 2023-12-08 普雷西根公司 人乳头瘤病毒疫苗及其用于hpv相关疾病的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN443995A0 (en) * 1995-07-27 1995-08-17 Csl Limited Papillomavirus polyprotein
WO2002008435A1 (en) * 2000-07-21 2002-01-31 Glaxo Group Limited Codon-optimized papilloma virus sequences
GB0017990D0 (en) * 2000-07-21 2000-09-13 Glaxo Group Ltd Papilloma virus sequences

Also Published As

Publication number Publication date
MXPA05003558A (es) 2005-06-03
AR041515A1 (es) 2005-05-18
MA27474A1 (fr) 2005-08-01
JP2006516386A (ja) 2006-07-06
TW200411055A (en) 2004-07-01
CN1720261A (zh) 2006-01-11
RU2005109155A (ru) 2006-03-10
NO20051561D0 (no) 2005-03-23
WO2004031222A3 (en) 2004-08-19
CN100393878C (zh) 2008-06-11
GB0222953D0 (en) 2002-11-13
WO2004031222A2 (en) 2004-04-15
RU2354701C2 (ru) 2009-05-10
CA2500093A1 (en) 2004-04-15
US20060165713A1 (en) 2006-07-27
EP1546191A2 (en) 2005-06-29
CO5580837A2 (es) 2005-11-30
NZ539154A (en) 2007-05-31
BR0314986A (pt) 2005-08-09
AU2003294672A1 (en) 2004-04-23
US20070264283A1 (en) 2007-11-15
NO20051561L (no) 2005-06-02
PL376534A1 (pl) 2006-01-09
IS7775A (is) 2005-03-29
KR20050050115A (ko) 2005-05-27

Similar Documents

Publication Publication Date Title
EP1301614B1 (en) Codon-optimized papilloma virus sequences
Liu et al. Polynucleotide viral vaccines: codon optimisation and ubiquitin conjugation enhances prophylactic and therapeutic efficacy
AU2001275695A1 (en) Codon-optimized papilloma virus sequences
US20070264283A1 (en) Vaccine
US7132262B2 (en) Papilloma virus sequences
EP0561885B1 (en) Subunit papillomavirus vaccine
US6183745B1 (en) Subunit papilloma virus vaccine and peptides for use therein
WO2008145745A1 (en) Vaccine against hpv
JP4317786B2 (ja) gp350/220非スプライシング変異体
AU708460B2 (en) A polynucleotide herpes virus vaccine
US20050118139A1 (en) Vaccine using papilloma virus e proteins delivered by viral vector
CA2444048C (en) Novel immunogenic compositions comprising modified and unmodified antigens
WO2025030015A1 (en) Cmv-based human papillomavirus vaccines
AU660954B2 (en) Subunit papillomavirus vaccine and peptides for use therein
Poláková Gene Immunotherapy of Cancer: DNA Vaccines against HPV 16