ZA200503039B - Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy - Google Patents
Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy Download PDFInfo
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- ZA200503039B ZA200503039B ZA200503039A ZA200503039A ZA200503039B ZA 200503039 B ZA200503039 B ZA 200503039B ZA 200503039 A ZA200503039 A ZA 200503039A ZA 200503039 A ZA200503039 A ZA 200503039A ZA 200503039 B ZA200503039 B ZA 200503039B
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ZA200503039A ZA200503039B (en) | 2002-10-11 | 2005-04-14 | Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy |
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US (3) | US7279313B2 (de) |
EP (1) | EP1549735B1 (de) |
JP (2) | JP4522861B2 (de) |
KR (1) | KR101323542B1 (de) |
CN (2) | CN100491521C (de) |
AT (1) | ATE521695T1 (de) |
AU (2) | AU2003287078B2 (de) |
BR (1) | BR0314512A (de) |
CA (1) | CA2501851C (de) |
CY (1) | CY1112110T1 (de) |
DK (1) | DK1549735T3 (de) |
ES (1) | ES2372599T3 (de) |
HK (2) | HK1082761B (de) |
IL (1) | IL167706A (de) |
MX (1) | MXPA05003857A (de) |
NO (1) | NO333932B1 (de) |
NZ (2) | NZ539311A (de) |
PT (1) | PT1549735E (de) |
RU (1) | RU2307870C2 (de) |
SI (1) | SI1549735T1 (de) |
WO (1) | WO2004033664A2 (de) |
ZA (1) | ZA200503039B (de) |
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FR2738842B1 (fr) * | 1995-09-15 | 1997-10-31 | Rhone Poulenc Rorer Sa | Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique |
FR2822476B1 (fr) * | 2001-03-23 | 2004-04-02 | Aventis Pharma Sa | Procedes de purification et de detection de sequences cibles d'adn double brin par interaction triple helice |
SI1737945T1 (sl) | 2004-04-19 | 2011-05-31 | Aventis Pharma Sa | Postopek za čiščenje plazmidne DNA |
JP4581851B2 (ja) * | 2004-07-27 | 2010-11-17 | セイコーエプソン株式会社 | 電気光学装置の駆動回路及び駆動方法、電気光学装置並びに電子機器 |
FR2920158B1 (fr) * | 2007-08-24 | 2010-03-12 | Centre Nat Rech Scient | Production de plasmides et expression de proteines recombinantes dans des cellules cultivees sans antibiotiques |
EP2221066A1 (de) | 2009-02-18 | 2010-08-25 | Sanofi-Aventis | Verwendung des VgII3-Aktivitätsmodulators zur Modulierung von Adipogenese |
EP2471909A1 (de) * | 2010-12-30 | 2012-07-04 | SIRION BIOTECH GmbH | Nukleinsäuremoleküle zur Herstellung adenoviraler Vektoren |
JP5863338B2 (ja) * | 2011-08-25 | 2016-02-16 | 株式会社東芝 | プラスミド型ベクター、遺伝子プロモーター活性の検出方法、及びアッセイキット |
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WO2014077863A1 (en) | 2012-11-19 | 2014-05-22 | Nature Technology Corporation | Replicative minicircle vectors with improved expression |
EP3561062A1 (de) | 2013-09-13 | 2019-10-30 | California Institute of Technology | Selektive rückgewinnung |
US10301672B2 (en) * | 2014-11-18 | 2019-05-28 | Japan Science And Technology Agency | Method of amplifying circular DNA |
US10086089B2 (en) | 2015-09-18 | 2018-10-02 | DNARx | Systems and methods for nucleic acid expression in vivo |
WO2017100671A1 (en) | 2015-12-11 | 2017-06-15 | California Institute Of Technology | TARGETING PEPTIDES FOR DIRECTING ADENO-ASSOCIATED VIRUSES (AAVs) |
CA3057320A1 (en) * | 2017-03-23 | 2018-09-27 | DNARx | Systems and methods for nucleic acid expression in vivo |
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EP3911749A1 (de) * | 2019-01-18 | 2021-11-24 | Janssen Biotech, Inc. | Alpha-peptid von beta-galactosidase als nicht-antibiotischer selektionsmarker und dessen verwendungen |
WO2023069895A1 (en) * | 2021-10-18 | 2023-04-27 | Modernatx, Inc. | Markerless dna production |
WO2023241567A1 (zh) * | 2022-06-13 | 2023-12-21 | 南京金斯瑞生物科技有限公司 | 一种可提高无筛选标签质粒制备效率的野生型-突变体π蛋白切换表达系统 |
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2002
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- 2003-10-14 ES ES03777599T patent/ES2372599T3/es not_active Expired - Lifetime
- 2003-10-14 KR KR1020057006228A patent/KR101323542B1/ko not_active IP Right Cessation
- 2003-10-14 EP EP03777599A patent/EP1549735B1/de not_active Expired - Lifetime
- 2003-10-14 PT PT03777599T patent/PT1549735E/pt unknown
- 2003-10-14 MX MXPA05003857A patent/MXPA05003857A/es active IP Right Grant
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- 2003-10-14 WO PCT/US2003/032512 patent/WO2004033664A2/en active Application Filing
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