ZA200502042B - Antidepressant piperidine derivatives of heterocycle-fused benzodioxans - Google Patents
Antidepressant piperidine derivatives of heterocycle-fused benzodioxans Download PDFInfo
- Publication number
- ZA200502042B ZA200502042B ZA200502042A ZA200502042A ZA200502042B ZA 200502042 B ZA200502042 B ZA 200502042B ZA 200502042 A ZA200502042 A ZA 200502042A ZA 200502042 A ZA200502042 A ZA 200502042A ZA 200502042 B ZA200502042 B ZA 200502042B
- Authority
- ZA
- South Africa
- Prior art keywords
- carbon atoms
- dihydro
- compound
- pharmaceutically acceptable
- acceptable salt
- Prior art date
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 208000002271 trichotillomania Diseases 0.000 description 1
- MWKJTNBSKNUMFN-UHFFFAOYSA-N trifluoromethyltrimethylsilane Chemical compound C[Si](C)(C)C(F)(F)F MWKJTNBSKNUMFN-UHFFFAOYSA-N 0.000 description 1
- 229910000404 tripotassium phosphate Inorganic materials 0.000 description 1
- 235000019798 tripotassium phosphate Nutrition 0.000 description 1
- 206010046494 urge incontinence Diseases 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- OYPPVKRFBIWMSX-SXGWCWSVSA-N zimeldine Chemical compound C=1C=CN=CC=1C(=C/CN(C)C)\C1=CC=C(Br)C=C1 OYPPVKRFBIWMSX-SXGWCWSVSA-N 0.000 description 1
- 229960002791 zimeldine Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41003302P | 2002-09-12 | 2002-09-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200502042B true ZA200502042B (en) | 2006-08-30 |
Family
ID=31994047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200502042A ZA200502042B (en) | 2002-09-12 | 2005-03-10 | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
Country Status (13)
Country | Link |
---|---|
US (3) | US6939877B2 (fr) |
EP (1) | EP1537120A1 (fr) |
JP (1) | JP2006510594A (fr) |
KR (1) | KR20050042192A (fr) |
CN (2) | CN100351256C (fr) |
AU (1) | AU2003270559A1 (fr) |
BR (1) | BR0314431A (fr) |
EC (1) | ECSP055657A (fr) |
MX (1) | MXPA05002830A (fr) |
NO (1) | NO20051617D0 (fr) |
RU (1) | RU2005107588A (fr) |
WO (1) | WO2004024733A1 (fr) |
ZA (1) | ZA200502042B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6939877B2 (en) * | 2002-09-12 | 2005-09-06 | Wyeth | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
AR052674A1 (es) * | 2005-02-17 | 2007-03-28 | Wyeth Corp | Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilcondensados |
AR060493A1 (es) * | 2006-04-18 | 2008-06-18 | Wyeth Corp | Derivados de benzodioxano y benzodioxolano. procesos de obtencion. |
CN101563342B (zh) * | 2006-12-21 | 2012-09-05 | 伊莱利利公司 | 用于治疗癌症的咪唑啉酮基氨基嘧啶化合物 |
WO2008150848A1 (fr) * | 2007-05-30 | 2008-12-11 | Wyeth | Dérivés d'hétéro-aryle antidépresseurs de benzodioxanes condensés avec un hétérocycle |
US8399432B2 (en) * | 2009-10-27 | 2013-03-19 | Lipogen Ltd. | Compositions and methods of treatment for alleviating premenstrual syndrome symptoms |
WO2012114347A1 (fr) * | 2011-02-21 | 2012-08-30 | Avra Laboratories Pvt. Ltd. | Synthèse de benzènes substitués chiraux et composés aromatiques correspondants contenant des diols 1,2 protégés en tant que groupes diacétal |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2266677A (en) * | 1941-12-16 | Garden implement | ||
US1706658A (en) * | 1927-04-15 | 1929-03-26 | Winthrop S Davis | Hoe |
US3293674A (en) * | 1965-04-02 | 1966-12-27 | Sapia James | Combination sickle and weed pulling tool |
GB1354554A (en) | 1970-08-31 | 1974-06-05 | Robins Co Inc A H | 2-substituted benzimidazoles |
US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
PH23995A (en) | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
US5364866A (en) | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
JPH05505599A (ja) * | 1990-03-15 | 1993-08-19 | ジ・アップジョン・カンパニー | 治療上有用な複素環インドール化合物類 |
CA2096853A1 (fr) * | 1990-11-24 | 1992-05-25 | Anthony Michael Johnson | Emploi de la paroxetine pour le traitement de la demence senile, de la boulimie, de la migraine ou de l'anorexie |
CA2137673C (fr) | 1992-07-13 | 2005-09-06 | Jan Vandenberk | Nouveaux derives 4-[3-benzofuranyl]piperidinyliques et 4-[3-benzothienyl]piperidinyliques |
US5276042A (en) * | 1993-04-16 | 1994-01-04 | Crenshaw Roger T | Treatment of premature ejaculation |
GB9318431D0 (en) * | 1993-09-06 | 1993-10-20 | Boots Co Plc | Therapeutic agents |
GB9402029D0 (en) * | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
US5756532A (en) * | 1995-11-06 | 1998-05-26 | American Home Products Corporation | Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives |
DE19602355A1 (de) * | 1996-01-24 | 1997-07-31 | Hoechst Ag | Mehrfach fucosylierte Dicarbonsäuren mit antiadhäsiven Eigenschaften |
ES2196312T3 (es) | 1996-10-15 | 2003-12-16 | Wyeth Corp | Derivados azaheterociclimetilo de 3,3,9 -tetrahidro-7h 1,4-dioxino (2,3-4) indol-8-0na. |
US5869490A (en) * | 1996-10-15 | 1999-02-09 | American Home Products Corporation | Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one |
GB9627005D0 (en) * | 1996-12-27 | 1997-02-12 | Knoll Ag | Therapeutic agents |
GB9704948D0 (en) | 1997-03-11 | 1997-04-30 | Knoll Ag | Therapeutic agents |
TWI242011B (en) * | 1997-03-31 | 2005-10-21 | Eisai Co Ltd | 1,4-substituted cyclic amine derivatives |
US6720003B2 (en) * | 2001-02-16 | 2004-04-13 | Andrx Corporation | Serotonin reuptake inhibitor formulations |
US6458802B1 (en) * | 2001-03-14 | 2002-10-01 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline |
US6593350B2 (en) * | 2001-04-26 | 2003-07-15 | Wyeth | Antidepressant indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino[2,3-e]indole |
US6939877B2 (en) * | 2002-09-12 | 2005-09-06 | Wyeth | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
-
2003
- 2003-09-10 US US10/659,160 patent/US6939877B2/en not_active Expired - Fee Related
- 2003-09-11 CN CNB038214687A patent/CN100351256C/zh not_active Expired - Fee Related
- 2003-09-11 WO PCT/US2003/028523 patent/WO2004024733A1/fr active Application Filing
- 2003-09-11 AU AU2003270559A patent/AU2003270559A1/en not_active Abandoned
- 2003-09-11 BR BR0314431-3A patent/BR0314431A/pt not_active IP Right Cessation
- 2003-09-11 KR KR1020057004124A patent/KR20050042192A/ko not_active Application Discontinuation
- 2003-09-11 CN CNA2007101523868A patent/CN101230066A/zh active Pending
- 2003-09-11 RU RU2005107588/04A patent/RU2005107588A/ru not_active Application Discontinuation
- 2003-09-11 JP JP2004536506A patent/JP2006510594A/ja active Pending
- 2003-09-11 MX MXPA05002830A patent/MXPA05002830A/es active IP Right Grant
- 2003-09-11 EP EP03752260A patent/EP1537120A1/fr not_active Withdrawn
-
2005
- 2005-03-10 EC EC2005005657A patent/ECSP055657A/es unknown
- 2005-03-10 ZA ZA200502042A patent/ZA200502042B/en unknown
- 2005-03-31 NO NO20051617A patent/NO20051617D0/no not_active Application Discontinuation
- 2005-06-01 US US11/142,787 patent/US7479500B2/en not_active Expired - Fee Related
-
2008
- 2008-10-20 US US12/254,118 patent/US20090042895A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1537120A1 (fr) | 2005-06-08 |
KR20050042192A (ko) | 2005-05-04 |
MXPA05002830A (es) | 2005-08-16 |
US20040147523A1 (en) | 2004-07-29 |
ECSP055657A (es) | 2005-07-06 |
US6939877B2 (en) | 2005-09-06 |
JP2006510594A (ja) | 2006-03-30 |
BR0314431A (pt) | 2005-09-27 |
NO20051617L (no) | 2005-03-31 |
RU2005107588A (ru) | 2006-01-20 |
US7479500B2 (en) | 2009-01-20 |
CN100351256C (zh) | 2007-11-28 |
WO2004024733A1 (fr) | 2004-03-25 |
AU2003270559A1 (en) | 2004-04-30 |
CN1681820A (zh) | 2005-10-12 |
US20050228009A1 (en) | 2005-10-13 |
NO20051617D0 (no) | 2005-03-31 |
CN101230066A (zh) | 2008-07-30 |
US20090042895A1 (en) | 2009-02-12 |
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