ZA200406889B - Aggrecanase molecules - Google Patents

Aggrecanase molecules

Info

Publication number
ZA200406889B
ZA200406889B ZA200406889A ZA200406889A ZA200406889B ZA 200406889 B ZA200406889 B ZA 200406889B ZA 200406889 A ZA200406889 A ZA 200406889A ZA 200406889 A ZA200406889 A ZA 200406889A ZA 200406889 B ZA200406889 B ZA 200406889B
Authority
ZA
South Africa
Prior art keywords
aggrecanase molecules
aggrecanase
molecules
Prior art date
Application number
ZA200406889A
Other languages
English (en)
Inventor
Christopher Corcoran
Michael J Agostino
Vallie Edward La
Bethany Freeman
Weilan Zeng
Lisa Collins-Racie
Carl R Flannery
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ZA200406889B publication Critical patent/ZA200406889B/xx

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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
ZA200406889A 2002-01-31 2004-08-30 Aggrecanase molecules ZA200406889B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35368002P 2002-01-31 2002-01-31

Publications (1)

Publication Number Publication Date
ZA200406889B true ZA200406889B (en) 2010-02-24

Family

ID=27663239

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200406889A ZA200406889B (en) 2002-01-31 2004-08-30 Aggrecanase molecules

Country Status (10)

Country Link
US (2) US7078217B2 (ja)
EP (1) EP1476545A4 (ja)
JP (1) JP2005515779A (ja)
KR (1) KR20040077928A (ja)
AU (2) AU2003207795B2 (ja)
CA (1) CA2474908A1 (ja)
PL (1) PL371525A1 (ja)
SG (1) SG158739A1 (ja)
WO (1) WO2003064622A2 (ja)
ZA (1) ZA200406889B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070009529A1 (en) * 2002-03-26 2007-01-11 New York University Agents that dissolve arterial thrombi
US20030226656A1 (en) 2001-06-01 2003-12-11 Junji Harada Total heat exchanging element-use paper
WO2004055158A2 (en) * 2001-10-05 2004-07-01 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
JP2005516614A (ja) * 2002-02-05 2005-06-09 ワイス 切断アグレカナーゼ分子
EP1525307A2 (en) * 2002-07-29 2005-04-27 Wyeth Modified adamts4 molecules and method of use thereof
AU2005236023A1 (en) * 2004-04-16 2005-11-03 Wyeth Truncated adamts molecules
CN101283106A (zh) * 2005-07-27 2008-10-08 肿瘤疗法科学股份有限公司 小细胞肺癌的诊断方法
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
CN102850433B (zh) 2006-10-17 2016-03-02 肿瘤疗法科学股份有限公司 用于表达mphosph1或depdc1多肽的癌症的肽疫苗
EP1953660A1 (en) * 2006-12-11 2008-08-06 Konica Minolta Medical & Graphic, Inc. Radiographying system and radiation image detecting device
EP2174661B1 (en) 2007-06-29 2012-12-19 National University Corporation Nagoya University Agent for improving neuropathic pain
US8753631B2 (en) * 2009-05-01 2014-06-17 New York University Therapeutic agents for inducing platelet fragmentation and treating thromboembolic disorders
GB201312311D0 (en) * 2013-07-09 2013-08-21 Uni I Oslo Uses of enzyme inhibitors
IL257335B (en) 2015-08-12 2022-08-01 Oncotherapy Science Inc A depdc1-derived peptide and a component containing it

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4588684A (en) 1983-04-26 1986-05-13 Chiron Corporation a-Factor and its processing signals
ZA848495B (en) 1984-01-31 1985-09-25 Idaho Res Found Production of polypeptides in insect cells
IE60819B1 (en) 1984-07-06 1994-08-10 Sandoz Ltd Lymphokine production and purification
DE3586386T2 (de) 1984-10-05 1993-01-14 Genentech Inc Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung.
CA2247827A1 (en) * 1996-03-01 1997-09-04 The Procter & Gamble Company A novel disintegrin metalloprotease and methods of use
WO2000005256A1 (en) * 1998-07-24 2000-02-03 Du Pont Pharmaceuticals Company Assays and peptide substrate for determining aggrecan degrading metallo protease activity
AU2001259473A1 (en) * 2000-05-04 2001-11-12 Sugen, Inc. Novel proteases
US6927056B2 (en) * 2001-09-06 2005-08-09 Incyte Corporation Proteases
WO2002020736A2 (en) * 2000-09-08 2002-03-14 Incyte Genomics Inc Proteases
JP3800175B2 (ja) 2000-12-18 2006-07-26 アステラス製薬株式会社 新規なアグリカナーゼ
US20040018555A1 (en) * 2001-06-04 2004-01-29 Anderson David W. Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use

Also Published As

Publication number Publication date
CA2474908A1 (en) 2003-08-07
US7078217B2 (en) 2006-07-18
WO2003064622A2 (en) 2003-08-07
JP2005515779A (ja) 2005-06-02
WO2003064622A3 (en) 2003-11-27
KR20040077928A (ko) 2004-09-07
AU2009201274A1 (en) 2009-04-23
SG158739A1 (en) 2010-02-26
EP1476545A4 (en) 2006-11-29
US20070128616A1 (en) 2007-06-07
AU2003207795B2 (en) 2009-01-08
EP1476545A2 (en) 2004-11-17
PL371525A1 (en) 2005-06-27
US20040044194A1 (en) 2004-03-04

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