ZA200406245B - Azaspiro compounds for the treatment of pain. - Google Patents
Azaspiro compounds for the treatment of pain.Info
- Publication number
- ZA200406245B ZA200406245B ZA200406245A ZA200406245A ZA200406245B ZA 200406245 B ZA200406245 B ZA 200406245B ZA 200406245 A ZA200406245 A ZA 200406245A ZA 200406245 A ZA200406245 A ZA 200406245A ZA 200406245 B ZA200406245 B ZA 200406245B
- Authority
- ZA
- South Africa
- Prior art keywords
- amino
- amido
- sulfonyl
- cooh
- cho
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10210190A DE10210190A1 (de) | 2002-03-07 | 2002-03-07 | Aza-Spiroverbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200406245B true ZA200406245B (en) | 2005-06-13 |
Family
ID=27771112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200406245A ZA200406245B (en) | 2002-03-07 | 2004-08-05 | Azaspiro compounds for the treatment of pain. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20050288351A1 (ja) |
| EP (2) | EP1485352B1 (ja) |
| JP (1) | JP2005526745A (ja) |
| KR (1) | KR20040091638A (ja) |
| CN (1) | CN1324011C (ja) |
| AT (1) | ATE298745T1 (ja) |
| AU (1) | AU2003215603A1 (ja) |
| BR (1) | BR0307922A (ja) |
| CA (1) | CA2477124A1 (ja) |
| DE (2) | DE10210190A1 (ja) |
| ES (1) | ES2242944T3 (ja) |
| HK (1) | HK1080468A1 (ja) |
| MX (1) | MXPA04008669A (ja) |
| NO (1) | NO20044239L (ja) |
| PL (1) | PL372431A1 (ja) |
| PT (1) | PT1485352E (ja) |
| RU (1) | RU2322438C2 (ja) |
| UA (1) | UA78987C2 (ja) |
| WO (1) | WO2003074486A1 (ja) |
| ZA (1) | ZA200406245B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201607923A (zh) * | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環（４．５）癸烷衍生物 |
| CN107216335B (zh) * | 2017-06-29 | 2019-04-30 | 上海药明康德新药开发有限公司 | 一种叔丁基1-(羟甲基)-3-氧杂-9-氮杂螺[5.5]十一烷-9-甲酸基酯制法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2866734A (en) * | 1956-12-05 | 1958-12-30 | Us Vitamin Corp | 3-pyridylethyl 2, 4-oxazolidinediones and process |
| US3150143A (en) * | 1960-07-19 | 1964-09-22 | Geschicketer Fund For Medical | Therapeutically active nu-substituted azaspiranes |
| US3629276A (en) * | 1969-07-16 | 1971-12-21 | Abbott Lab | 2-amino-5-spiro-substituted-oxazo compounds |
| US4430335A (en) * | 1983-02-09 | 1984-02-07 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 1-azaspiro[4,5]decanes and their analgesic compositions |
| GB8916447D0 (en) * | 1989-07-19 | 1989-09-06 | Ici Plc | Composition,process and use |
| US5319135A (en) * | 1989-08-25 | 1994-06-07 | Warner-Lambert Company | Process for cyclic amino acid anticonvulsant compounds |
| US5132451A (en) * | 1989-08-25 | 1992-07-21 | Warner-Lambert Company | Process for cyclic amino acid anticonvulsant compounds |
| US5925672A (en) * | 1996-12-06 | 1999-07-20 | Neurosciences Research Foundation, Inc. | Methods of treating mental diseases, inflammation and pain |
| DE19732928C2 (de) * | 1997-07-31 | 2000-05-18 | Gruenenthal Gmbh | Verwendung substituierter Imidazolidin-2,4-dion-Verbindungen als Schmerzmittel |
| US5948807A (en) * | 1997-09-03 | 1999-09-07 | Regents Of The University Of Minnesota | Spiroindanamines and Spiroindanimides |
| DE19751062A1 (de) * | 1997-11-18 | 1999-07-08 | Univ Ludwigs Albert | An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels |
| AU757445B2 (en) * | 1998-05-26 | 2003-02-20 | Warner-Lambert Company | Conformationally constrained amino acid compounds having affinity for the alpha2delta subunit of a calcium channel |
-
2002
- 2002-03-07 DE DE10210190A patent/DE10210190A1/de not_active Ceased
-
2003
- 2003-02-27 EP EP03743342A patent/EP1485352B1/de not_active Expired - Lifetime
- 2003-02-27 CN CNB038054388A patent/CN1324011C/zh not_active Expired - Fee Related
- 2003-02-27 RU RU2004129769/04A patent/RU2322438C2/ru not_active IP Right Cessation
- 2003-02-27 AU AU2003215603A patent/AU2003215603A1/en not_active Abandoned
- 2003-02-27 ES ES03743342T patent/ES2242944T3/es not_active Expired - Lifetime
- 2003-02-27 KR KR10-2004-7012680A patent/KR20040091638A/ko not_active Application Discontinuation
- 2003-02-27 JP JP2003572956A patent/JP2005526745A/ja active Pending
- 2003-02-27 AT AT03743342T patent/ATE298745T1/de not_active IP Right Cessation
- 2003-02-27 BR BR0307922-8A patent/BR0307922A/pt not_active IP Right Cessation
- 2003-02-27 EP EP04029311A patent/EP1520854A3/de not_active Withdrawn
- 2003-02-27 CA CA002477124A patent/CA2477124A1/en not_active Abandoned
- 2003-02-27 PT PT03743342T patent/PT1485352E/pt unknown
- 2003-02-27 MX MXPA04008669A patent/MXPA04008669A/es not_active Application Discontinuation
- 2003-02-27 PL PL03372431A patent/PL372431A1/xx not_active Application Discontinuation
- 2003-02-27 WO PCT/EP2003/001986 patent/WO2003074486A1/de active IP Right Grant
- 2003-02-27 UA UA20041008091A patent/UA78987C2/uk unknown
- 2003-02-27 DE DE50300710T patent/DE50300710D1/de not_active Expired - Fee Related
-
2004
- 2004-08-05 ZA ZA200406245A patent/ZA200406245B/xx unknown
- 2004-09-07 US US10/936,134 patent/US20050288351A1/en not_active Abandoned
- 2004-10-06 NO NO20044239A patent/NO20044239L/no not_active Application Discontinuation
-
2006
- 2006-01-06 HK HK06100281A patent/HK1080468A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003215603A2 (en) | 2003-09-16 |
| EP1485352A1 (de) | 2004-12-15 |
| WO2003074486A1 (de) | 2003-09-12 |
| ATE298745T1 (de) | 2005-07-15 |
| EP1520854A3 (de) | 2007-02-21 |
| HK1080468A1 (en) | 2006-04-28 |
| JP2005526745A (ja) | 2005-09-08 |
| DE10210190A1 (de) | 2003-09-25 |
| ES2242944T3 (es) | 2005-11-16 |
| US20050288351A1 (en) | 2005-12-29 |
| EP1485352B1 (de) | 2005-06-29 |
| AU2003215603A1 (en) | 2003-09-16 |
| PL372431A1 (en) | 2005-07-25 |
| NO20044239L (no) | 2004-12-01 |
| CA2477124A1 (en) | 2003-09-12 |
| RU2322438C2 (ru) | 2008-04-20 |
| UA78987C2 (en) | 2007-05-10 |
| DE50300710D1 (de) | 2005-08-04 |
| KR20040091638A (ko) | 2004-10-28 |
| EP1520854A2 (de) | 2005-04-06 |
| MXPA04008669A (es) | 2004-12-06 |
| BR0307922A (pt) | 2004-12-21 |
| CN1639122A (zh) | 2005-07-13 |
| RU2004129769A (ru) | 2005-07-10 |
| CN1324011C (zh) | 2007-07-04 |
| PT1485352E (pt) | 2005-10-31 |
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