ZA200402235B - Bio-sensing platforms for detection and quantitation of biological molecules. - Google Patents
Bio-sensing platforms for detection and quantitation of biological molecules. Download PDFInfo
- Publication number
- ZA200402235B ZA200402235B ZA200402235A ZA200402235A ZA200402235B ZA 200402235 B ZA200402235 B ZA 200402235B ZA 200402235 A ZA200402235 A ZA 200402235A ZA 200402235 A ZA200402235 A ZA 200402235A ZA 200402235 B ZA200402235 B ZA 200402235B
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- South Africa
- Prior art keywords
- fluorescence
- fluorescer
- bioconjugate
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y20/00—Nanooptics, e.g. quantum optics or photonic crystals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Theoretical Computer Science (AREA)
- Mathematical Physics (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31409401P | 2001-08-23 | 2001-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200402235B true ZA200402235B (en) | 2005-08-29 |
Family
ID=23218522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200402235A ZA200402235B (en) | 2001-08-23 | 2002-08-23 | Bio-sensing platforms for detection and quantitation of biological molecules. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20030054413A1 (fr) |
EP (1) | EP1425581A4 (fr) |
JP (1) | JP2005501248A (fr) |
KR (1) | KR20040083411A (fr) |
CA (1) | CA2458405A1 (fr) |
IL (1) | IL160519A0 (fr) |
NO (1) | NO20041160L (fr) |
WO (1) | WO2003019138A2 (fr) |
ZA (1) | ZA200402235B (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050147534A1 (en) * | 1998-05-05 | 2005-07-07 | Massachusetts Institute Of Technology | Emissive sensors and devices incorporating these sensors |
EP1080162B1 (fr) * | 1998-05-05 | 2004-03-10 | Massachusetts Institute Of Technology | Polymeres emissifs et dispositifs renfermant ces polymeres |
US8198096B2 (en) | 1998-05-05 | 2012-06-12 | Massachusetts Institute Of Technology | Emissive polymers and devices incorporating these polymers |
EP1437594B1 (fr) * | 2001-09-19 | 2011-01-12 | Sekisui Medical Co., Ltd. | Polymere luminescent utilisable dans des bioessais |
US7462325B2 (en) * | 2001-11-30 | 2008-12-09 | Nomadics, Inc. | Luminescent polymer particles |
US7335478B2 (en) * | 2002-04-18 | 2008-02-26 | Kalobios Pharmaceuticals, Inc. | Reactivation-based molecular interaction sensors |
US7432063B2 (en) * | 2002-02-14 | 2008-10-07 | Kalobios Pharmaceuticals, Inc. | Methods for affinity maturation |
US9371559B2 (en) | 2002-06-20 | 2016-06-21 | The Regents Of The University Of California | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
US7270956B2 (en) | 2002-08-26 | 2007-09-18 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
US10001475B2 (en) | 2002-06-20 | 2018-06-19 | The Regents Of The University Of California | Light harvesting multichromophore compositions and methods of using the same |
CN1675377B (zh) | 2002-06-20 | 2012-10-03 | 加州大学评议会 | 利用获取光的多发色团检测和分析多核苷酸的方法和组合物 |
US7144950B2 (en) * | 2003-09-17 | 2006-12-05 | The Regents Of The University Of California | Conformationally flexible cationic conjugated polymers |
EP1579215A4 (fr) * | 2002-11-14 | 2007-01-17 | Qtl Biosystems Llc | Procedes de biodetection utilisant des polymeres fluorescents et bioconjugues de type extincteur-chaine-ligand (qtl) |
ES2440920T3 (es) | 2003-02-13 | 2014-01-31 | The Regents Of The University Of California | Métodos y composiciones para la detección y análisis de interacciones de proteínas que se unen a polinucleótidos utilizando multicromóforos captadores de luz |
WO2004072266A2 (fr) * | 2003-02-13 | 2004-08-26 | Kalobios Inc. | Ingenierie de l'affinite des anticorps par un remplacement complementaire en serie guide par epitope |
EP1601955B1 (fr) | 2003-03-07 | 2013-01-09 | Luxcel Biosciences Limited | Sonde sensible a l'oxygène et procède pour mesurer l'absorption d'oxygène |
AU2003243850A1 (en) * | 2003-06-18 | 2005-01-04 | Bratya Vassilevi Ad | Refrigerator and system of refrigerators |
US9017766B2 (en) | 2003-09-17 | 2015-04-28 | The Regents Of The University Of California | Methods and devices comprising soluble conjugated polymers |
EP1692703A4 (fr) * | 2003-12-12 | 2007-11-28 | Qtl Biosystems Llc | Essais, kits et reactifs de superextinction de fluorescence induite par des ions metalliques |
US20060088895A1 (en) * | 2004-01-30 | 2006-04-27 | Wanders Bart J | Systems, methods and reagents for the detection of biological and chemical agents using dynamic surface generation and imaging |
EP1716252A1 (fr) * | 2004-02-19 | 2006-11-02 | University College Cork-National University of Ireland, Cork | Detection de composes actifs sur le plan biologique |
DE112005002132T5 (de) * | 2004-09-03 | 2008-03-06 | The Regents Of The University Of California, Oakland | Lösliche konjugierte Polymere |
US8795781B2 (en) * | 2004-09-03 | 2014-08-05 | The Regents Of The University Of California | Methods and devices utilizing soluble conjugated polymers |
WO2006034081A2 (fr) * | 2004-09-17 | 2006-03-30 | Massachusetts Institute Of Technology | Polymeres destines a la detection d'analytes |
EP1824975B9 (fr) * | 2004-11-09 | 2011-04-20 | Santaris Pharma A/S | Oligonucleotides lna et traitement du cancer |
WO2006074482A2 (fr) * | 2005-01-10 | 2006-07-13 | The Regents Of The University Of California | Procedes et articles pour la detection de polynucleotides specifiques de brin a multichromophores cationiques |
EP1838752B1 (fr) | 2005-01-10 | 2017-10-04 | The Regents of The University of California | Polymeres conjugues cationiques appropries pour la detection de polynucleotides specifiques de brins dans des essais a l'etat solide et homogenes |
WO2006075429A1 (fr) * | 2005-01-13 | 2006-07-20 | Kyushu Institute Of Technology | Particule pour la detection de l’activite enzymatique et procede et outil de detection de l’activite enzymatique l’utilisant |
WO2006083932A2 (fr) | 2005-01-31 | 2006-08-10 | The Regents Of The University | Procedes et compositions permettant de detecter un agregat |
KR100704011B1 (ko) * | 2005-02-16 | 2007-04-04 | 한국과학기술원 | 금속나노입자와 양자점의 fret에 의한 생체분자특이결합 검출 방법 |
JP5529382B2 (ja) * | 2005-03-01 | 2014-06-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 固体照明に用いられる多層ポリマー発光ダイオード |
US20060292653A1 (en) * | 2005-03-18 | 2006-12-28 | Frauke Rininsland | Metal mediated fluorescence superquenching assays for detection of phosphorylation and dephosphorylation of quencher-labeled substrates |
KR100806669B1 (ko) * | 2005-06-23 | 2008-02-26 | 김정환 | 나노 입자-생체 복합체 |
KR100727413B1 (ko) * | 2005-08-26 | 2007-06-13 | 경북대학교 산학협력단 | 의료용 분자 이미징을 위한, 생체 적합성 고분자로 코팅된NIR Q-dot의 제조 방법 |
JP2009540333A (ja) | 2006-06-12 | 2009-11-19 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | ナノセンサーおよび関連技術 |
US8158437B2 (en) * | 2006-08-04 | 2012-04-17 | Massachusetts Institute Of Technology | Luminescent detection of hydrazine and hydrazine derivatives |
WO2008042289A2 (fr) | 2006-09-29 | 2008-04-10 | Massachusetts Institute Of Technology | Technique synthétique polymérique |
US8802447B2 (en) * | 2006-10-05 | 2014-08-12 | Massachusetts Institute Of Technology | Emissive compositions with internal standard and related techniques |
US20090215189A1 (en) | 2006-10-27 | 2009-08-27 | Massachusetts Institute Of Technology | Sensor of species including toxins and chemical warfare agents |
KR100809402B1 (ko) * | 2007-01-29 | 2008-03-05 | 김정환 | 나노 입자 표지, 나노 입자 표지를 이용하는 진단 키트, 및진단 방법 |
KR100914455B1 (ko) * | 2007-05-28 | 2009-08-28 | 전남대학교산학협력단 | 양자점을 이용한 생물학적 검출키트 및 방법 |
US20110039289A1 (en) * | 2008-03-14 | 2011-02-17 | Pierre Graves | Fluorogenic peptides and their method of production |
WO2011038228A1 (fr) * | 2009-09-24 | 2011-03-31 | President And Fellows Of Harvard College | Nanofils incurvés et détection associée d'espèces |
CN104245960B (zh) * | 2012-02-21 | 2018-11-09 | 美国控股实验室公司 | 用于生物测定的信号放大的方法和系统 |
GB2502306A (en) * | 2012-05-22 | 2013-11-27 | Univ Singapore | Microparticle sensor |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0428000A1 (fr) * | 1989-11-03 | 1991-05-22 | Abbott Laboratories | Substrats fluorogéniques pour la détection de l'activité prothéolytique d'enzymes |
GB9310978D0 (en) * | 1993-05-27 | 1993-07-14 | Zeneca Ltd | Compounds |
US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
US5605809A (en) * | 1994-10-28 | 1997-02-25 | Oncoimmunin, Inc. | Compositions for the detection of proteases in biological samples and methods of use thereof |
US6803188B1 (en) * | 1996-01-31 | 2004-10-12 | The Regents Of The University Of California | Tandem fluorescent protein constructs |
WO1998041866A1 (fr) * | 1997-03-14 | 1998-09-24 | Merck & Co., Inc. | Dosage a haute capacite dans lequel des proteines de fusion sont utilisees |
US6251583B1 (en) * | 1998-04-27 | 2001-06-26 | Schering Corporation | Peptide substrates for HCV NS3 protease assays |
US6210896B1 (en) * | 1998-08-13 | 2001-04-03 | Us Genomics | Molecular motors |
-
2002
- 2002-08-23 IL IL16051902A patent/IL160519A0/xx unknown
- 2002-08-23 CA CA002458405A patent/CA2458405A1/fr not_active Abandoned
- 2002-08-23 KR KR10-2004-7002669A patent/KR20040083411A/ko not_active Application Discontinuation
- 2002-08-23 EP EP02766054A patent/EP1425581A4/fr not_active Withdrawn
- 2002-08-23 ZA ZA200402235A patent/ZA200402235B/en unknown
- 2002-08-23 WO PCT/US2002/026697 patent/WO2003019138A2/fr not_active Application Discontinuation
- 2002-08-23 JP JP2003523958A patent/JP2005501248A/ja active Pending
- 2002-08-23 US US10/226,300 patent/US20030054413A1/en not_active Abandoned
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2004
- 2004-03-22 NO NO20041160A patent/NO20041160L/no not_active Application Discontinuation
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EP1425581A2 (fr) | 2004-06-09 |
JP2005501248A (ja) | 2005-01-13 |
KR20040083411A (ko) | 2004-10-01 |
NO20041160L (no) | 2004-03-22 |
CA2458405A1 (fr) | 2003-03-06 |
IL160519A0 (en) | 2004-07-25 |
EP1425581A4 (fr) | 2005-03-09 |
US20030054413A1 (en) | 2003-03-20 |
WO2003019138A2 (fr) | 2003-03-06 |
WO2003019138A3 (fr) | 2003-11-06 |
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