ZA200308770B - Method of treating dry eye disorders. - Google Patents

Method of treating dry eye disorders. Download PDF

Info

Publication number
ZA200308770B
ZA200308770B ZA200308770A ZA200308770A ZA200308770B ZA 200308770 B ZA200308770 B ZA 200308770B ZA 200308770 A ZA200308770 A ZA 200308770A ZA 200308770 A ZA200308770 A ZA 200308770A ZA 200308770 B ZA200308770 B ZA 200308770B
Authority
ZA
South Africa
Prior art keywords
dry eye
eye
compositions
stigmastan
pentahydroxy
Prior art date
Application number
ZA200308770A
Other languages
English (en)
Inventor
Daniel A Gamache
John M Yanni
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of ZA200308770B publication Critical patent/ZA200308770B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA200308770A 2001-05-21 2003-11-11 Method of treating dry eye disorders. ZA200308770B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29250001P 2001-05-21 2001-05-21

Publications (1)

Publication Number Publication Date
ZA200308770B true ZA200308770B (en) 2004-11-23

Family

ID=23124938

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200308770A ZA200308770B (en) 2001-05-21 2003-11-11 Method of treating dry eye disorders.

Country Status (10)

Country Link
US (1) US20030008853A1 (ja)
EP (1) EP1392322A1 (ja)
JP (1) JP2004531560A (ja)
CN (1) CN1239161C (ja)
BR (1) BR0209882A (ja)
CA (1) CA2447918A1 (ja)
MX (1) MXPA03010633A (ja)
PL (1) PL367097A1 (ja)
WO (1) WO2002094284A1 (ja)
ZA (1) ZA200308770B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1744759B1 (en) 2004-03-25 2009-09-02 Bausch & Lomb Incorporated Use of loteprednol etabonate for the treatment of dry eye
ES2413804T3 (es) * 2006-05-19 2013-07-17 Alcon Research, Ltd. Inhibición mediada por ARNi de estados relacionados con factor de necrosis tumoral-alfa
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US527851A (en) * 1894-10-23 Process of reducing aluminium
US3991759A (en) * 1975-10-28 1976-11-16 Alza Corporation Method and therapeutic system for treating aqueous deficient dry eye
US4131651A (en) * 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) * 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4370325A (en) * 1979-03-30 1983-01-25 Dermik Laboratories Pharmaceutical compositions and method of treatment
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4804539A (en) * 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5174988A (en) * 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
US5583150A (en) * 1989-08-18 1996-12-10 Alcon Laboratories, Inc. 5-methyl-isoxazole-4-carboxylic acid anilides and 2-hydroxyethylidene-cyano acetic anilides for the treatment of ocular diseases
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
ZA912797B (en) * 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
ES2084722T3 (es) * 1990-05-29 1996-05-16 Boston Ocular Res Composicion para tratamiento del ojo seco.
ATE141502T1 (de) * 1991-01-15 1996-09-15 Alcon Lab Inc Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen
US5958912A (en) * 1992-04-21 1999-09-28 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens of TGF-β
JPH07508716A (ja) * 1992-04-21 1995-09-28 ザ スキーペンズ アイ リサーチ インスティテュート,インコーポレイテッド シェーグレン症候群における眼のアンドロゲン療法
US6107289A (en) * 1992-04-21 2000-08-22 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens or TGF-β
US5506221A (en) * 1992-12-24 1996-04-09 University Of British Columbia Contignasterol, and related 3-alpha hydroxy-6-alpha hydroxy-7-beta hydroxy-15-keto-14-beta steroids useful as anti-inflammatory and anti-thrombosis agents
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
WO1997020578A1 (en) * 1995-12-04 1997-06-12 University Of Miami Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance
US6046185A (en) * 1996-07-11 2000-04-04 Inflazyme Pharmaceuticals Ltd. 6,7-oxygenated steroids and uses related thereto
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
EP0998925A4 (en) * 1997-05-26 2003-02-26 New Vision Co Ltd TOPICAL ADMINISTRATION COMPOSITIONS CONTAINING VITAMINS D AND VITAMINS K
US6096733A (en) * 1998-12-10 2000-08-01 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
AU2002252705A1 (en) * 2001-04-19 2002-11-05 Bristol-Myers Squibb Company Polynucleotides and polypeptides associated with the nf-kb pathway
US20040076691A1 (en) * 2002-01-16 2004-04-22 David Haines Anti-inflammatory formulations

Also Published As

Publication number Publication date
CN1239161C (zh) 2006-02-01
EP1392322A1 (en) 2004-03-03
US20030008853A1 (en) 2003-01-09
MXPA03010633A (es) 2004-03-09
WO2002094284A1 (en) 2002-11-28
CN1509177A (zh) 2004-06-30
BR0209882A (pt) 2004-06-08
PL367097A1 (en) 2005-02-21
CA2447918A1 (en) 2002-11-28
JP2004531560A (ja) 2004-10-14

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