ZA200304560B - Ccr5 antagonist and dp-178 polypeptide for treating viral infections - Google Patents
Ccr5 antagonist and dp-178 polypeptide for treating viral infections Download PDFInfo
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- ZA200304560B ZA200304560B ZA2003/04560A ZA200304560A ZA200304560B ZA 200304560 B ZA200304560 B ZA 200304560B ZA 2003/04560 A ZA2003/04560 A ZA 2003/04560A ZA 200304560 A ZA200304560 A ZA 200304560A ZA 200304560 B ZA200304560 B ZA 200304560B
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- pharmaceutically acceptable
- composition
- substance
- polypeptide
- treatment
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- 239000011885 synergistic combination Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 102000035160 transmembrane proteins Human genes 0.000 description 1
- 108091005703 transmembrane proteins Proteins 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 230000007486 viral budding Effects 0.000 description 1
- 230000007502 viral entry Effects 0.000 description 1
- 229940098802 viramune Drugs 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 229940087450 zerit Drugs 0.000 description 1
- 229940052255 ziagen Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25665700P | 2000-12-19 | 2000-12-19 | |
| PCT/US2001/048802 WO2002056902A2 (en) | 2000-12-19 | 2001-12-17 | Ccr5 antagonist and dp-178 polypeptide for treating viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200304560B true ZA200304560B (en) | 2005-07-27 |
Family
ID=22973061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2003/04560A ZA200304560B (en) | 2000-12-19 | 2003-06-11 | Ccr5 antagonist and dp-178 polypeptide for treating viral infections |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050065319A1 (enExample) |
| EP (1) | EP1385534A2 (enExample) |
| JP (1) | JP2005500981A (enExample) |
| CN (1) | CN1481251A (enExample) |
| AR (1) | AR031931A1 (enExample) |
| BR (1) | BR0116253A (enExample) |
| CA (1) | CA2431919A1 (enExample) |
| HU (1) | HUP0302241A3 (enExample) |
| MX (1) | MXPA03005526A (enExample) |
| NO (1) | NO20032769L (enExample) |
| WO (1) | WO2002056902A2 (enExample) |
| ZA (1) | ZA200304560B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2400553A (en) * | 2003-04-14 | 2004-10-20 | Cipla Ltd | Antiviral pharmaceutical combination of lamivudine, stavudine and efavirenz, or derivatives thereof |
| BRPI0410360A (pt) * | 2003-05-16 | 2006-08-01 | Univ Maryland Biotech Inst | composições para a sub-regulação da expressão de ccr5 e métodos para seu uso |
| CA2587903A1 (en) | 2004-11-17 | 2006-05-26 | Amgen Fremont Inc. | Fully human monoclonal antibodies to il-13 |
| JP2009517474A (ja) * | 2005-11-30 | 2009-04-30 | シェーリング コーポレイション | Ｃｃｒ５拮抗剤およびｃｘｃｒ４拮抗剤の組み合わせを含む組成物 |
| EP1976497A2 (en) * | 2005-12-01 | 2008-10-08 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Treatment of viral infections |
| EP1886696A1 (en) * | 2006-08-03 | 2008-02-13 | Endotis Pharma | Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins |
| WO2013127299A1 (zh) * | 2012-02-28 | 2013-09-06 | 中国人民解放军军事医学科学院毒物药物研究所 | 用于抑制hiv的多肽及其作用靶点 |
| US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5464933A (en) * | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| CA2224008C (en) * | 1995-06-07 | 2009-08-18 | Trimeris, Inc. | The treatment of hiv and other viral infections using combinatorial therapy |
| US6281331B1 (en) * | 1998-03-23 | 2001-08-28 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
| CA2365900A1 (en) * | 1999-05-04 | 2000-11-09 | Schering Corporation | Pegylated interferon alfa-ccr5 antagonist combination hiv therapy |
| US6391865B1 (en) * | 1999-05-04 | 2002-05-21 | Schering Corporation | Piperazine derivatives useful as CCR5 antagonists |
| US6689765B2 (en) * | 1999-05-04 | 2004-02-10 | Schering Corporation | Piperazine derivatives useful as CCR5 antagonists |
| PT1175402E (pt) * | 1999-05-04 | 2005-11-30 | Schering Corp | Derivados da piperidina uteis como antagonistas ccr5 |
| US6387930B1 (en) * | 1999-05-04 | 2002-05-14 | Schering Corporation | Piperidine derivatives useful as CCR5 antagonists |
-
2001
- 2001-06-11 US US10/168,295 patent/US20050065319A1/en not_active Abandoned
- 2001-12-17 BR BRPI0116253-5A patent/BR0116253A/pt not_active IP Right Cessation
- 2001-12-17 EP EP01993303A patent/EP1385534A2/en not_active Withdrawn
- 2001-12-17 MX MXPA03005526A patent/MXPA03005526A/es unknown
- 2001-12-17 CA CA002431919A patent/CA2431919A1/en not_active Abandoned
- 2001-12-17 HU HU0302241A patent/HUP0302241A3/hu unknown
- 2001-12-17 AR ARP010105840A patent/AR031931A1/es unknown
- 2001-12-17 CN CNA01820919XA patent/CN1481251A/zh active Pending
- 2001-12-17 JP JP2002557409A patent/JP2005500981A/ja active Pending
- 2001-12-17 WO PCT/US2001/048802 patent/WO2002056902A2/en not_active Ceased
-
2003
- 2003-06-11 ZA ZA2003/04560A patent/ZA200304560B/en unknown
- 2003-06-18 NO NO20032769A patent/NO20032769L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20032769L (no) | 2003-08-18 |
| HUP0302241A2 (hu) | 2003-11-28 |
| US20050065319A1 (en) | 2005-03-24 |
| WO2002056902A3 (en) | 2002-12-05 |
| WO2002056902A2 (en) | 2002-07-25 |
| CA2431919A1 (en) | 2002-07-25 |
| BR0116253A (pt) | 2006-05-02 |
| MXPA03005526A (es) | 2003-10-06 |
| EP1385534A2 (en) | 2004-02-04 |
| CN1481251A (zh) | 2004-03-10 |
| JP2005500981A (ja) | 2005-01-13 |
| HUP0302241A3 (en) | 2005-06-28 |
| NO20032769D0 (no) | 2003-06-18 |
| AR031931A1 (es) | 2003-10-08 |
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