ZA200300122B - Compositions and methods of preventing or reducing the risk of incidence of skeletal injuries in horses. - Google Patents
Compositions and methods of preventing or reducing the risk of incidence of skeletal injuries in horses. Download PDFInfo
- Publication number
- ZA200300122B ZA200300122B ZA200300122A ZA200300122A ZA200300122B ZA 200300122 B ZA200300122 B ZA 200300122B ZA 200300122 A ZA200300122 A ZA 200300122A ZA 200300122 A ZA200300122 A ZA 200300122A ZA 200300122 B ZA200300122 B ZA 200300122B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutically acceptable
- bisphosphonate
- horses
- acceptable salt
- alendronate
- Prior art date
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- CAKRAHQRJGUPIG-UHFFFAOYSA-M sodium;[4-azaniumyl-1-hydroxy-1-[hydroxy(oxido)phosphoryl]butyl]-hydroxyphosphinate Chemical compound [Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O CAKRAHQRJGUPIG-UHFFFAOYSA-M 0.000 description 1
- VBDRTGFACFYFCT-UHFFFAOYSA-M sodium;hydroxy-[(1r)-1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphinate;hydrate Chemical compound O.[Na+].CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)([O-])=O VBDRTGFACFYFCT-UHFFFAOYSA-M 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000007939 sustained release tablet Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 229940037128 systemic glucocorticoids Drugs 0.000 description 1
- 210000000457 tarsus Anatomy 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229950002757 teoclate Drugs 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000004797 therapeutic response Effects 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 150000004684 trihydrates Chemical class 0.000 description 1
- SOBHUZYZLFQYFK-UHFFFAOYSA-K trisodium;hydroxy-[[phosphonatomethyl(phosphonomethyl)amino]methyl]phosphinate Chemical compound [Na+].[Na+].[Na+].OP(O)(=O)CN(CP(O)([O-])=O)CP([O-])([O-])=O SOBHUZYZLFQYFK-UHFFFAOYSA-K 0.000 description 1
- 229940070710 valerate Drugs 0.000 description 1
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 229930195724 β-lactose Natural products 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Feed For Specific Animals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21966800P | 2000-07-21 | 2000-07-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200300122B true ZA200300122B (en) | 2003-11-13 |
Family
ID=22820225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200300122A ZA200300122B (en) | 2000-07-21 | 2003-01-06 | Compositions and methods of preventing or reducing the risk of incidence of skeletal injuries in horses. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6638920B2 (fr) |
| EP (1) | EP1305032A4 (fr) |
| JP (1) | JP2004504352A (fr) |
| AU (2) | AU7790401A (fr) |
| CA (1) | CA2418167C (fr) |
| NZ (1) | NZ523391A (fr) |
| WO (1) | WO2002007734A1 (fr) |
| ZA (1) | ZA200300122B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2347330C (fr) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Preparation injectable liquide de pamidronate disodique |
| SK2532004A3 (en) * | 2001-12-21 | 2004-11-03 | Procter & Gamble | Method for the treatment of bone disorders |
| KR100998856B1 (ko) * | 2002-02-14 | 2010-12-08 | 규큐 야쿠힝 고교 가부시키가이샤 | 경피투여제제 |
| KR20120065435A (ko) * | 2002-05-10 | 2012-06-20 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
| SG174628A1 (en) * | 2002-12-20 | 2011-10-28 | Hoffmann La Roche | High dose ibandronate formulation |
| WO2005066190A1 (fr) * | 2004-01-02 | 2005-07-21 | Hexal A/S | Nouveaux sels de risedronate |
| WO2006039721A2 (fr) * | 2004-10-08 | 2006-04-13 | The Board Of Trustees Of The University Of Illinois | Composes de bisphosphonate et methodes de traitement de maladies de resorption osseuse, de cancers, de douleurs osseuses, de troubles immunitaires et de maladies infectieuses |
| US8012949B2 (en) * | 2004-10-08 | 2011-09-06 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| EP1888606A2 (fr) * | 2005-05-28 | 2008-02-20 | PLIVA HRVATSKA d.o.o. | Nouveau sel et procede associe |
| DE102005053512A1 (de) * | 2005-11-09 | 2007-06-28 | Omnimedic Gbr | Verwendung von Clodronsäure zur Behandlung von Podotrochlose |
| AU2007226964B2 (en) * | 2006-03-17 | 2012-03-22 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods |
| AU2009274229B2 (en) * | 2008-07-21 | 2013-08-22 | Otonomy, Inc. | Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders |
| FR2954320B1 (fr) * | 2009-12-17 | 2012-06-15 | Cll Pharma | Composition pharmaceutique orale suprabiodisponible contenant un acide biphosphonique ou un de ses sels |
| WO2011132826A1 (fr) * | 2010-04-19 | 2011-10-27 | Snu R&Db Foundation | Système d'administration transdermique de médicaments et composition pharmaceutique pour la prévention ou le traitement de maladies osseuses |
| US8865757B1 (en) * | 2014-05-28 | 2014-10-21 | Antecip Bioventures Ii Llp | Therapeutic compositions comprising imidazole and imidazolium compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2405254C2 (de) | 1974-02-04 | 1982-05-27 | Henkel KGaA, 4000 Düsseldorf | Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper |
| IT1201087B (it) | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| US5358941A (en) | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
| ATE290871T1 (de) | 1995-09-29 | 2005-04-15 | Novartis Pharma Gmbh | Verfahren zur behandlung navikularer krankheiten bei pferden |
| US5994329A (en) | 1997-07-22 | 1999-11-30 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| KR20030097610A (ko) * | 1997-07-22 | 2003-12-31 | 머크 앤드 캄파니 인코포레이티드 | 골 흡수 억제를 위한 조성물 |
| SE9703691D0 (sv) * | 1997-10-10 | 1997-10-10 | Astra Ab | Pharmaceutical compositions |
| EP0950417A3 (fr) * | 1998-02-23 | 2000-02-23 | Pfizer Products Inc. | Traitement d' anomalies du squelette |
| FR2784031B1 (fr) * | 1998-10-02 | 2002-02-01 | Sanofi Elf | Utilisation de derives de l'acide bisphosphonique pour la preparation d'un medicament destine au traitement des boiteries |
| AR013994A1 (es) * | 1998-10-30 | 2001-01-31 | Gador Sa | Procedimiento y preparaciones que modulan selectivamente la funcion del osteoblasto para la prevencion y tratamiento de las osteopatias fragilizantes. |
| US6331533B1 (en) | 1998-11-16 | 2001-12-18 | Merck & Co., Inc. | Method for inhibiting dental resorptive lesions |
| AU1525700A (en) * | 1998-11-19 | 2000-06-05 | Board Of Trustees Of The University Of Arkansas, The | Increasing bone strength with selected bisphosphonates |
-
2001
- 2001-07-11 US US09/902,913 patent/US6638920B2/en not_active Expired - Lifetime
- 2001-07-17 NZ NZ523391A patent/NZ523391A/en not_active IP Right Cessation
- 2001-07-17 WO PCT/US2001/022470 patent/WO2002007734A1/fr active IP Right Grant
- 2001-07-17 CA CA002418167A patent/CA2418167C/fr not_active Expired - Lifetime
- 2001-07-17 EP EP01955850A patent/EP1305032A4/fr not_active Withdrawn
- 2001-07-17 JP JP2002513469A patent/JP2004504352A/ja active Pending
- 2001-07-17 AU AU7790401A patent/AU7790401A/xx active Pending
- 2001-07-17 AU AU2001277904A patent/AU2001277904B2/en not_active Expired
-
2003
- 2003-01-06 ZA ZA200300122A patent/ZA200300122B/en unknown
- 2003-08-22 US US10/646,593 patent/US20040038944A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020033144A1 (en) | 2002-03-21 |
| CA2418167C (fr) | 2009-01-27 |
| JP2004504352A (ja) | 2004-02-12 |
| EP1305032A1 (fr) | 2003-05-02 |
| CA2418167A1 (fr) | 2002-01-31 |
| WO2002007734A1 (fr) | 2002-01-31 |
| AU7790401A (en) | 2002-02-05 |
| AU2001277904B2 (en) | 2005-04-21 |
| EP1305032A4 (fr) | 2009-04-08 |
| NZ523391A (en) | 2004-07-30 |
| US20040038944A1 (en) | 2004-02-26 |
| US6638920B2 (en) | 2003-10-28 |
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