ZA200208963B - Neucleotide sequences involved in increasing or decreasing mammalian ovulation rate. - Google Patents
Neucleotide sequences involved in increasing or decreasing mammalian ovulation rate. Download PDFInfo
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- ZA200208963B ZA200208963B ZA200208963A ZA200208963A ZA200208963B ZA 200208963 B ZA200208963 B ZA 200208963B ZA 200208963 A ZA200208963 A ZA 200208963A ZA 200208963 A ZA200208963 A ZA 200208963A ZA 200208963 B ZA200208963 B ZA 200208963B
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- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229960000310 isoleucine Drugs 0.000 description 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
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- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000010369 molecular cloning Methods 0.000 description 1
- 239000003068 molecular probe Substances 0.000 description 1
- 238000007491 morphometric analysis Methods 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 239000002853 nucleic acid probe Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229950009506 penicillinase Drugs 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 238000005204 segregation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
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- 238000000844 transformation Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ500844A NZ500844A (en) | 2000-05-05 | 2000-05-05 | Nucleotide sequences (mutated GDF-9B polypeptides) involved in increasing and decreasing mammalian ovulation rate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200208963B true ZA200208963B (en) | 2004-07-26 |
Family
ID=19927611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200208963A ZA200208963B (en) | 2000-05-05 | 2002-11-06 | Neucleotide sequences involved in increasing or decreasing mammalian ovulation rate. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20040092007A1 (https=) |
| EP (1) | EP1292674B1 (https=) |
| JP (1) | JP2003532414A (https=) |
| CN (1) | CN1436237A (https=) |
| AR (1) | AR028411A1 (https=) |
| AT (1) | ATE401403T1 (https=) |
| AU (2) | AU6082101A (https=) |
| BR (1) | BR0110616A (https=) |
| CA (1) | CA2408051A1 (https=) |
| DE (1) | DE60134852D1 (https=) |
| MX (1) | MXPA02010868A (https=) |
| NZ (1) | NZ500844A (https=) |
| RU (1) | RU2283866C2 (https=) |
| WO (1) | WO2001085926A2 (https=) |
| ZA (1) | ZA200208963B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ502796A (en) * | 2000-06-15 | 2003-02-28 | Agres Ltd | Nucleotide and amino acid sequences of oocyte factors related to GDF-9B or GDF-9 |
| NZ519330A (en) * | 2002-05-30 | 2004-12-24 | George Henry Davis | New sequences for altering mammalian ovarian function and ovulation rate |
| BRPI0518900A2 (pt) * | 2004-12-02 | 2008-12-16 | Agres Ltd | modulaÇço de ovulaÇço |
| ATE487800T1 (de) * | 2005-09-13 | 2010-11-15 | Neocodex S L | Verfahren zum in-vitro-nachweis einer veranlagung zur entwicklung von veränderungen der ovarienfunktion |
| ES2338960B1 (es) * | 2007-11-23 | 2011-04-19 | Carnes Oviaragon S.C.L. | Procedimiento de mejora de la productividad en ganado ovino. |
| CN105210981B (zh) * | 2015-09-15 | 2018-09-28 | 中国科学院生物物理研究所 | 建立可应用于人类疾病研究的雪貂模型的方法及其应用 |
| CN105941325A (zh) * | 2016-06-17 | 2016-09-21 | 安徽省农业科学院畜牧兽医研究所 | 小尾寒羊母羊与澳洲白公羊杂交生产澳寒杂交母羊的方法 |
| CN106614366A (zh) * | 2016-12-29 | 2017-05-10 | 李振民 | 一种无抗生猪养殖方法 |
| CN108753835A (zh) * | 2018-05-30 | 2018-11-06 | 中山大学 | 一种利用CRISPR/Cas9编辑猪BMP15基因的方法 |
| CN111440879A (zh) * | 2020-04-27 | 2020-07-24 | 内蒙古大学 | 一种利用gdf9基因提高蒙古羊繁殖力的方法 |
| CN111500744A (zh) * | 2020-04-27 | 2020-08-07 | 内蒙古大学 | 一种基于gdf9基因编码区突变的蒙古羊繁殖力提高方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635372A (en) * | 1995-05-18 | 1997-06-03 | Genetics Institute, Inc. | BMP-15 compositions |
-
2000
- 2000-05-05 NZ NZ500844A patent/NZ500844A/xx not_active IP Right Cessation
-
2001
- 2001-05-04 AT AT01934660T patent/ATE401403T1/de not_active IP Right Cessation
- 2001-05-04 AU AU6082101A patent/AU6082101A/xx active Pending
- 2001-05-04 JP JP2001582515A patent/JP2003532414A/ja active Pending
- 2001-05-04 AU AU2001260821A patent/AU2001260821B2/en not_active Ceased
- 2001-05-04 AR ARP010102128A patent/AR028411A1/es unknown
- 2001-05-04 RU RU2002132655/13A patent/RU2283866C2/ru not_active IP Right Cessation
- 2001-05-04 CA CA002408051A patent/CA2408051A1/en not_active Abandoned
- 2001-05-04 MX MXPA02010868A patent/MXPA02010868A/es unknown
- 2001-05-04 CN CN01811320A patent/CN1436237A/zh active Pending
- 2001-05-04 WO PCT/NZ2001/000073 patent/WO2001085926A2/en not_active Ceased
- 2001-05-04 DE DE60134852T patent/DE60134852D1/de not_active Expired - Fee Related
- 2001-05-04 BR BR0110616-3A patent/BR0110616A/pt not_active IP Right Cessation
- 2001-05-04 EP EP01934660A patent/EP1292674B1/en not_active Expired - Lifetime
- 2001-05-04 US US10/275,503 patent/US20040092007A1/en not_active Abandoned
-
2002
- 2002-11-06 ZA ZA200208963A patent/ZA200208963B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE401403T1 (de) | 2008-08-15 |
| NZ500844A (en) | 2003-06-30 |
| MXPA02010868A (es) | 2004-09-06 |
| BR0110616A (pt) | 2004-04-06 |
| AU2001260821B2 (en) | 2006-04-13 |
| EP1292674A2 (en) | 2003-03-19 |
| WO2001085926A2 (en) | 2001-11-15 |
| CN1436237A (zh) | 2003-08-13 |
| CA2408051A1 (en) | 2001-11-15 |
| RU2283866C2 (ru) | 2006-09-20 |
| EP1292674B1 (en) | 2008-07-16 |
| US20040092007A1 (en) | 2004-05-13 |
| AU6082101A (en) | 2001-11-20 |
| WO2001085926A3 (en) | 2002-08-08 |
| AR028411A1 (es) | 2003-05-07 |
| DE60134852D1 (de) | 2008-08-28 |
| JP2003532414A (ja) | 2003-11-05 |
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