MXPA02010868A - Secuencias de nucleotidos involucrados en el incremento o disminucion en la ovulacion mamifera. - Google Patents

Secuencias de nucleotidos involucrados en el incremento o disminucion en la ovulacion mamifera.

Info

Publication number
MXPA02010868A
MXPA02010868A MXPA02010868A MXPA02010868A MXPA02010868A MX PA02010868 A MXPA02010868 A MX PA02010868A MX PA02010868 A MXPA02010868 A MX PA02010868A MX PA02010868 A MXPA02010868 A MX PA02010868A MX PA02010868 A MXPA02010868 A MX PA02010868A
Authority
MX
Mexico
Prior art keywords
increasing
ovulation rate
nucleotide sequences
mammals
gene
Prior art date
Application number
MXPA02010868A
Other languages
English (en)
Inventor
Kenneth Pattrick Mcnatty
Original Assignee
Agres Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agres Ltd filed Critical Agres Ltd
Publication of MXPA02010868A publication Critical patent/MXPA02010868A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se refiere a secuencias de nucleotidos que estan involucradas en aumentar o disminuir la velocidad de ovulacion de un mamifero. En particular, la invencion tiene que ver en general con mutaciones novedosas en un gen que esta involucrado en aumentar las velocidades de ovulacion en mamiferos hembra heterocigotos; estas mutaciones ocasionan esterilidad en mamiferos hembra homocigotos. El conocimiento de la secuencia de genes mutada puede aplicarse a una prueba para identificar mamiferos hembra y macho heterocigotos de homocigotos portando el gen mutado. Este conocimiento de la funcion biologica del gen y sus mutaciones puede utilizarse para aumentar o disminuir la velocidad de ovulacion de mamiferos hembra o para inducir la esterilidad o fertilidad reducida en mamiferos hembra.
MXPA02010868A 2000-05-05 2001-05-04 Secuencias de nucleotidos involucrados en el incremento o disminucion en la ovulacion mamifera. MXPA02010868A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ500844A NZ500844A (en) 2000-05-05 2000-05-05 Nucleotide sequences (mutated GDF-9B polypeptides) involved in increasing and decreasing mammalian ovulation rate
PCT/NZ2001/000073 WO2001085926A2 (en) 2000-05-05 2001-05-04 Nucleotide sequences involved in increasing or decreasing mammalian ovulation rate

Publications (1)

Publication Number Publication Date
MXPA02010868A true MXPA02010868A (es) 2004-09-06

Family

ID=19927611

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02010868A MXPA02010868A (es) 2000-05-05 2001-05-04 Secuencias de nucleotidos involucrados en el incremento o disminucion en la ovulacion mamifera.

Country Status (15)

Country Link
US (1) US20040092007A1 (es)
EP (1) EP1292674B1 (es)
JP (1) JP2003532414A (es)
CN (1) CN1436237A (es)
AR (1) AR028411A1 (es)
AT (1) ATE401403T1 (es)
AU (2) AU2001260821B2 (es)
BR (1) BR0110616A (es)
CA (1) CA2408051A1 (es)
DE (1) DE60134852D1 (es)
MX (1) MXPA02010868A (es)
NZ (1) NZ500844A (es)
RU (1) RU2283866C2 (es)
WO (1) WO2001085926A2 (es)
ZA (1) ZA200208963B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ502796A (en) * 2000-06-15 2003-02-28 Agres Ltd Nucleotide and amino acid sequences of oocyte factors related to GDF-9B or GDF-9
NZ519330A (en) * 2002-05-30 2004-12-24 George Henry Davis New sequences for altering mammalian ovarian function and ovulation rate
CA2590419A1 (en) * 2004-12-02 2006-06-08 Agresearch Limited Modulation of ovulation
ATE487800T1 (de) * 2005-09-13 2010-11-15 Neocodex S L Verfahren zum in-vitro-nachweis einer veranlagung zur entwicklung von veränderungen der ovarienfunktion
ES2338960B1 (es) * 2007-11-23 2011-04-19 Carnes Oviaragon S.C.L. Procedimiento de mejora de la productividad en ganado ovino.
CN105210981B (zh) * 2015-09-15 2018-09-28 中国科学院生物物理研究所 建立可应用于人类疾病研究的雪貂模型的方法及其应用
CN105941325A (zh) * 2016-06-17 2016-09-21 安徽省农业科学院畜牧兽医研究所 小尾寒羊母羊与澳洲白公羊杂交生产澳寒杂交母羊的方法
CN106614366A (zh) * 2016-12-29 2017-05-10 李振民 一种无抗生猪养殖方法
CN108753835A (zh) * 2018-05-30 2018-11-06 中山大学 一种利用CRISPR/Cas9编辑猪BMP15基因的方法
CN111500744A (zh) * 2020-04-27 2020-08-07 内蒙古大学 一种基于gdf9基因编码区突变的蒙古羊繁殖力提高方法
CN111440879A (zh) * 2020-04-27 2020-07-24 内蒙古大学 一种利用gdf9基因提高蒙古羊繁殖力的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635372A (en) * 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions

Also Published As

Publication number Publication date
NZ500844A (en) 2003-06-30
WO2001085926A3 (en) 2002-08-08
AU2001260821B2 (en) 2006-04-13
AU6082101A (en) 2001-11-20
CA2408051A1 (en) 2001-11-15
EP1292674B1 (en) 2008-07-16
JP2003532414A (ja) 2003-11-05
US20040092007A1 (en) 2004-05-13
CN1436237A (zh) 2003-08-13
RU2283866C2 (ru) 2006-09-20
AR028411A1 (es) 2003-05-07
DE60134852D1 (de) 2008-08-28
ATE401403T1 (de) 2008-08-15
WO2001085926A2 (en) 2001-11-15
EP1292674A2 (en) 2003-03-19
BR0110616A (pt) 2004-04-06
ZA200208963B (en) 2004-07-26

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