ZA200206803B - Production of foreign polypeptides in plants as viral coat protein fusions. - Google Patents

Production of foreign polypeptides in plants as viral coat protein fusions. Download PDF

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Publication number
ZA200206803B
ZA200206803B ZA200206803A ZA200206803A ZA200206803B ZA 200206803 B ZA200206803 B ZA 200206803B ZA 200206803 A ZA200206803 A ZA 200206803A ZA 200206803 A ZA200206803 A ZA 200206803A ZA 200206803 B ZA200206803 B ZA 200206803B
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ZA
South Africa
Prior art keywords
plant
virus
vcp
polynucleotide
recombinant
Prior art date
Application number
ZA200206803A
Other languages
English (en)
Inventor
Gregory P Pogue
John A Lindbo
Michael J Mcculloch
Jonathan E Lawrence
Cynthia S Gross
Stephen J Garger
Original Assignee
Large Scale Biology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Large Scale Biology Corp filed Critical Large Scale Biology Corp
Publication of ZA200206803B publication Critical patent/ZA200206803B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203Virus mediated transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/00022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
ZA200206803A 2000-03-08 2002-08-26 Production of foreign polypeptides in plants as viral coat protein fusions. ZA200206803B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/520,967 US6730306B1 (en) 2000-03-08 2000-03-08 Parvovirus vaccine as viral coat protein fusions

Publications (1)

Publication Number Publication Date
ZA200206803B true ZA200206803B (en) 2003-08-26

Family

ID=24074781

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200206803A ZA200206803B (en) 2000-03-08 2002-08-26 Production of foreign polypeptides in plants as viral coat protein fusions.

Country Status (7)

Country Link
US (5) US6730306B1 (ja)
EP (1) EP1266020A2 (ja)
JP (1) JP2003525619A (ja)
AU (2) AU4550901A (ja)
CA (1) CA2402302A1 (ja)
WO (1) WO2001066778A2 (ja)
ZA (1) ZA200206803B (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037456A (en) * 1998-03-10 2000-03-14 Biosource Technologies, Inc. Process for isolating and purifying viruses, soluble proteins and peptides from plant sources
ITRM20010332A1 (it) * 2001-06-11 2002-12-11 Ist Superiore Sanita Vaccini a subunita' e procedimenti per la loro produzione.
US20040033585A1 (en) 2002-06-07 2004-02-19 Mccormick Alison A. Flexible vaccine assembly and vaccine delivery platform
US20040170606A1 (en) * 2002-06-07 2004-09-02 Palmer Kenneth E. Production of peptides in plants as viral coat protein fusions
US8101189B2 (en) 2002-07-05 2012-01-24 Folia Biotech Inc. Vaccines and immunopotentiating compositions and methods for making and using them
CA2434000C (en) 2002-07-05 2012-07-17 Denis Leclerc Adjuvant viral particle
CA2497798A1 (en) * 2002-09-03 2004-04-22 Large Scale Biology Corporation Production of peptides in plants as viral coat protein fusions
SG153874A1 (en) 2003-12-31 2009-07-29 Schering Plough Ltd Neutralizing epitope-based growth enhancing vaccine
AU2005220734A1 (en) * 2004-02-27 2005-09-22 Dow Global Technologies Inc. High efficiency peptide production in plant cells
WO2005108564A2 (en) * 2004-03-25 2005-11-17 Large Scale Biology Corporation Production of peptides in plants as viral coat protein fusion
US20090053261A1 (en) * 2005-09-08 2009-02-26 Lindbo John A Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications
MY144766A (en) * 2004-12-30 2011-10-31 Schering Plough Ltd Plant virus coat fusion proteins with gdf8 epitopes and vaccines thereof
US8052971B2 (en) * 2005-11-21 2011-11-08 MG Biologics Oral use of specific antibodies for intestinal health
KR20090051031A (ko) * 2006-06-21 2009-05-20 유니버시티 오브 데이턴 편광 제어 방법 및 그의 응용
JP2010508857A (ja) 2006-11-15 2010-03-25 フォリア バイオテック インコーポレイテッド パパイヤモザイクウイルスに基づく免疫原性の親和性で複合体化された抗原系及びその使用
EP2118274A4 (en) * 2007-01-29 2010-09-01 Univ Ohio State Res Found GENE EXPRESSION SYSTEM IN PLANTS WITH A VIRUS-BASED EXPRESSION VECTOR
CN102634511B (zh) * 2012-04-13 2013-03-13 淮阴师范学院 成熟油菜次生休眠种子rna的提取方法
WO2019060703A1 (en) * 2017-09-22 2019-03-28 United States, As Represented By The Secretary Of The Army VIRAL PESUDO PARTICLES AND VACCINES BASED ON TOBAMOVIRUS
CN116640189A (zh) * 2023-04-13 2023-08-25 广东光峰生物技术有限公司 一种病原微生物快速检测试剂盒及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921802A (en) 1983-05-05 1990-05-01 Pioneer Hi-Bred International, Inc. Plant virus cDNA
US5977438A (en) * 1988-02-26 1999-11-02 Biosource Technologies, Inc. Production of peptides in plants as viral coat protein fusions
FR2633518B1 (fr) * 1988-06-30 1991-03-22 Merieux Inst Procede de stabilisation des vaccins et associations de vaccins a virus attenues conserves sous forme lyophilisee, et compositions obtenues
DK0647655T3 (da) * 1993-01-23 1999-08-23 Inmunologia & Genetica Aplic Syntetiske peptider og vacciner mod parvovirus
US5622822A (en) 1994-09-13 1997-04-22 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using polyethyleneimine and an anionic phosphate ester surfactant and amplification of same
CA2198966C (en) * 1996-03-04 2011-06-21 Yuji Suzuki Method for cleaving chimeric protein using processing enzyme
GB9607899D0 (en) 1996-04-17 1996-06-19 Scottish Crop Research Inst Virus-like particle
DK0912195T3 (da) 1996-06-25 2009-05-18 Pepscan Systems Bv Vaccine indeholdende antigener bundet til bærestoffer gennem labile bindinger
US6042832A (en) * 1996-08-28 2000-03-28 Thomas Jefferson University Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins
US6037456A (en) 1998-03-10 2000-03-14 Biosource Technologies, Inc. Process for isolating and purifying viruses, soluble proteins and peptides from plant sources
JP3313083B2 (ja) * 1998-03-31 2002-08-12 伊藤ハム株式会社 新規な融合蛋白質をコ―ドするdnaおよびその発現を介する有用ポリペプチドの製造方法
WO1999058662A1 (fr) * 1998-05-14 1999-11-18 Merck Patent Gmbh Proteine fusionnee

Also Published As

Publication number Publication date
WO2001066778A2 (en) 2001-09-13
WO2001066778A3 (en) 2002-05-10
US20030050463A1 (en) 2003-03-13
AU2001245509B2 (en) 2006-12-21
US7413889B2 (en) 2008-08-19
CA2402302A1 (en) 2001-09-13
US7270825B2 (en) 2007-09-18
US20030118596A1 (en) 2003-06-26
AU4550901A (en) 2001-09-17
EP1266020A2 (en) 2002-12-18
US6730306B1 (en) 2004-05-04
JP2003525619A (ja) 2003-09-02
US20030095986A1 (en) 2003-05-22
US20020192226A1 (en) 2002-12-19

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