ZA200203133B - Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina. - Google Patents
Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina. Download PDFInfo
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- ZA200203133B ZA200203133B ZA200203133A ZA200203133A ZA200203133B ZA 200203133 B ZA200203133 B ZA 200203133B ZA 200203133 A ZA200203133 A ZA 200203133A ZA 200203133 A ZA200203133 A ZA 200203133A ZA 200203133 B ZA200203133 B ZA 200203133B
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- South Africa
- Prior art keywords
- retinal
- betaxolol
- vol
- rats
- retina
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16799399P | 1999-11-30 | 1999-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200203133B true ZA200203133B (en) | 2003-04-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200203133A ZA200203133B (en) | 1999-11-30 | 2002-04-19 | Use of beta-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina. |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US7081482B2 (zh) |
| EP (1) | EP1244438B1 (zh) |
| JP (2) | JP4758581B2 (zh) |
| CN (1) | CN1245966C (zh) |
| AT (1) | ATE253905T1 (zh) |
| AU (1) | AU782524B2 (zh) |
| BR (1) | BR0015938A (zh) |
| CA (1) | CA2388728C (zh) |
| DE (1) | DE60006584T2 (zh) |
| DK (1) | DK1244438T3 (zh) |
| ES (1) | ES2210023T3 (zh) |
| HK (1) | HK1047695B (zh) |
| MX (1) | MXPA02005378A (zh) |
| PL (1) | PL214875B1 (zh) |
| PT (1) | PT1244438E (zh) |
| TR (1) | TR200302008T4 (zh) |
| WO (1) | WO2001043737A1 (zh) |
| ZA (1) | ZA200203133B (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7081482B2 (en) * | 1999-11-30 | 2006-07-25 | Alcon, Inc. | Use of β-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina |
| CN100413503C (zh) * | 2005-01-07 | 2008-08-27 | 冷文 | 一种复方眼药组合物 |
| WO2008080110A1 (en) * | 2006-12-21 | 2008-07-03 | Alcon, Inc. | Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor |
| JP2011513393A (ja) * | 2008-03-07 | 2011-04-28 | サン、ファーマ、アドバンスト、リサーチ、カンパニー、リミテッド | 眼用組成物 |
| US10267796B2 (en) * | 2010-10-25 | 2019-04-23 | The Procter & Gamble Company | Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis |
| CA3060417A1 (en) * | 2017-04-21 | 2018-10-25 | Steven Hoffman | Compositions and methods for treating retinopathy |
| EP3787749A4 (en) * | 2018-05-03 | 2022-01-26 | Alimera Sciences, Inc. | METHODS OF TREATMENT OF RETINAL DISEASES |
| CN116056693A (zh) * | 2020-07-10 | 2023-05-02 | 长庚医疗财团法人林口长庚纪念医院 | β-1肾上腺素受体拮抗剂用于制备减少表皮生长因子受体抑制剂诱导的上皮细胞损伤以及抑制癌细胞的组合物的用途 |
Family Cites Families (6)
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|---|---|---|---|---|
| FR2330383A1 (fr) | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| US4443432A (en) | 1981-10-05 | 1984-04-17 | Alcon Laboratories, Inc. | Ophthmalic irrigating solution |
| US5554367A (en) * | 1984-10-31 | 1996-09-10 | Alcon Laboratories, Inc. | Compositions for treatment of glaucoma |
| AU4582797A (en) | 1996-09-13 | 1998-04-02 | Regents Of The University Of California, The | Methods for treatment of retinal diseases |
| EP1115406A4 (en) * | 1998-09-25 | 2003-03-05 | Alcon Lab Inc | SUSTAINABLE RELEASE OPHTHALMIC COMPOSITION AND METHOD OF EYE THERAPY |
| US7081482B2 (en) * | 1999-11-30 | 2006-07-25 | Alcon, Inc. | Use of β-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina |
-
2000
- 2000-11-29 US US10/130,408 patent/US7081482B2/en not_active Expired - Fee Related
- 2000-11-29 TR TR2003/02008T patent/TR200302008T4/xx unknown
- 2000-11-29 CN CNB008163510A patent/CN1245966C/zh not_active Expired - Fee Related
- 2000-11-29 JP JP2001544676A patent/JP4758581B2/ja not_active Expired - Fee Related
- 2000-11-29 EP EP00983818A patent/EP1244438B1/en not_active Expired - Lifetime
- 2000-11-29 DK DK00983818T patent/DK1244438T3/da active
- 2000-11-29 DE DE60006584T patent/DE60006584T2/de not_active Expired - Lifetime
- 2000-11-29 WO PCT/US2000/032575 patent/WO2001043737A1/en active IP Right Grant
- 2000-11-29 CA CA002388728A patent/CA2388728C/en not_active Expired - Fee Related
- 2000-11-29 AT AT00983818T patent/ATE253905T1/de active
- 2000-11-29 MX MXPA02005378A patent/MXPA02005378A/es active IP Right Grant
- 2000-11-29 PL PL356001A patent/PL214875B1/pl unknown
- 2000-11-29 AU AU20527/01A patent/AU782524B2/en not_active Ceased
- 2000-11-29 PT PT00983818T patent/PT1244438E/pt unknown
- 2000-11-29 BR BR0015938-7A patent/BR0015938A/pt not_active Application Discontinuation
- 2000-11-29 ES ES00983818T patent/ES2210023T3/es not_active Expired - Lifetime
-
2002
- 2002-04-19 ZA ZA200203133A patent/ZA200203133B/en unknown
- 2002-11-16 HK HK02108325.7A patent/HK1047695B/zh not_active IP Right Cessation
-
2006
- 2006-05-02 US US11/415,824 patent/US20060199868A1/en not_active Abandoned
-
2008
- 2008-01-04 US US11/969,346 patent/US20080103211A1/en not_active Abandoned
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2010
- 2010-06-09 US US12/796,942 patent/US8710102B2/en not_active Expired - Fee Related
- 2010-07-06 JP JP2010154379A patent/JP2010215667A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1245966C (zh) | 2006-03-22 |
| PL356001A1 (en) | 2004-05-31 |
| PT1244438E (pt) | 2004-02-27 |
| DE60006584T2 (de) | 2004-09-30 |
| HK1047695A1 (en) | 2003-03-07 |
| US20060199868A1 (en) | 2006-09-07 |
| US7081482B2 (en) | 2006-07-25 |
| JP2010215667A (ja) | 2010-09-30 |
| DK1244438T3 (da) | 2004-02-23 |
| DE60006584D1 (de) | 2003-12-18 |
| HK1047695B (zh) | 2004-08-20 |
| ATE253905T1 (de) | 2003-11-15 |
| CA2388728C (en) | 2009-05-19 |
| TR200302008T4 (tr) | 2004-01-21 |
| US20080103211A1 (en) | 2008-05-01 |
| CA2388728A1 (en) | 2001-06-21 |
| EP1244438A1 (en) | 2002-10-02 |
| JP2003516963A (ja) | 2003-05-20 |
| ES2210023T3 (es) | 2004-07-01 |
| BR0015938A (pt) | 2002-08-27 |
| US8710102B2 (en) | 2014-04-29 |
| AU2052701A (en) | 2001-06-25 |
| AU782524B2 (en) | 2005-08-04 |
| US20100249134A1 (en) | 2010-09-30 |
| PL214875B1 (pl) | 2013-09-30 |
| JP4758581B2 (ja) | 2011-08-31 |
| WO2001043737A1 (en) | 2001-06-21 |
| US20020193373A1 (en) | 2002-12-19 |
| MXPA02005378A (es) | 2005-02-25 |
| EP1244438B1 (en) | 2003-11-12 |
| CN1402634A (zh) | 2003-03-12 |
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