ZA200202851B - A DNA molecule encoding a variant alpha2B-adrenoceptor protein, and uses thereof. - Google Patents

A DNA molecule encoding a variant alpha2B-adrenoceptor protein, and uses thereof.

Info

Publication number
ZA200202851B
ZA200202851B ZA200202851A ZA200202851A ZA200202851B ZA 200202851 B ZA200202851 B ZA 200202851B ZA 200202851 A ZA200202851 A ZA 200202851A ZA 200202851 A ZA200202851 A ZA 200202851A ZA 200202851 B ZA200202851 B ZA 200202851B
Authority
ZA
South Africa
Prior art keywords
alpha2b
variant
dna molecule
molecule encoding
adrenoceptor protein
Prior art date
Application number
ZA200202851A
Other languages
English (en)
Inventor
Amir Snapir
Paula Heinonen
Pia Alhopuro
Matti Karvonen
Markku Koulu
Ullamari Pesonen
Mika Scheinin
Jukka T Salonen
Tomi-Pekka Lakka Tim Tuomainen
Kristiina Nyyssoenen
Ritta Salonen
Jussi Kauhanen
Veli-Pekka Valkonen
Original Assignee
Juvantia Pharma Ltd Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juvantia Pharma Ltd Oy filed Critical Juvantia Pharma Ltd Oy
Publication of ZA200202851B publication Critical patent/ZA200202851B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA200202851A 1999-10-22 2002-04-11 A DNA molecule encoding a variant alpha2B-adrenoceptor protein, and uses thereof. ZA200202851B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42298599A 1999-10-22 1999-10-22

Publications (1)

Publication Number Publication Date
ZA200202851B true ZA200202851B (en) 2003-09-23

Family

ID=23677216

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200202851A ZA200202851B (en) 1999-10-22 2002-04-11 A DNA molecule encoding a variant alpha2B-adrenoceptor protein, and uses thereof.

Country Status (7)

Country Link
US (2) US6696556B2 (xx)
EP (1) EP1222204A1 (xx)
JP (1) JP2003512040A (xx)
CA (1) CA2387962A1 (xx)
HK (1) HK1047113A1 (xx)
WO (1) WO2001029082A1 (xx)
ZA (1) ZA200202851B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001079561A2 (en) * 2000-04-17 2001-10-25 Liggett Stephen B Alpha-2 adrenergic receptor polymorphisms
US7229756B1 (en) 2000-10-19 2007-06-12 University Of Cincinnati Alpha-2B-adrenergic receptor polymorphisms
US7211386B2 (en) 2000-08-10 2007-05-01 University Of Cincinnati Alpha-2A-adrenergic receptor polymorphisms
FI114483B (fi) * 2001-02-20 2004-10-29 Jurilab Ltd Oy Menetelmä kohonneen verenpaineen riskin osoittamiseksi ja sen käytöt
FI115532B (fi) * 2002-10-07 2005-05-31 Jurilab Ltd Oy Menetelmä kardiovaskulaaristen sairauksien riskin havaitsemiseksi
AU2003301503A1 (en) * 2003-12-16 2005-07-14 Centre National De La Recherche Scientifique Methods and compositions for assaying mutations in nucleic acids
TWI260717B (en) * 2004-05-17 2006-08-21 Mosel Vitelic Inc Ion-implantation method for forming a shallow junction
ATE469245T1 (de) 2004-09-14 2010-06-15 Univ Colorado Auf genetischem targeting basierendes verfahren zur behandlung mit bucindolol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5053337A (en) 1989-10-30 1991-10-01 Neurogenetic Corporation DNA encoding an α2B -adrenergic receptor
CA2145182C (en) * 1992-09-25 2001-09-18 Jonathan A. Bard Dna encoding human alpha 1 adrenergic receptors and uses thereof

Also Published As

Publication number Publication date
US20010016338A1 (en) 2001-08-23
HK1047113A1 (zh) 2003-02-07
US6696556B2 (en) 2004-02-24
WO2001029082A1 (en) 2001-04-26
CA2387962A1 (en) 2001-04-26
US20040152637A1 (en) 2004-08-05
JP2003512040A (ja) 2003-04-02
EP1222204A1 (en) 2002-07-17

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