ZA200004507B - Control of gene expression. - Google Patents

Control of gene expression.

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Publication number
ZA200004507B
ZA200004507B ZA200004507A ZA200004507A ZA200004507B ZA 200004507 B ZA200004507 B ZA 200004507B ZA 200004507 A ZA200004507 A ZA 200004507A ZA 200004507 A ZA200004507 A ZA 200004507A ZA 200004507 B ZA200004507 B ZA 200004507B
Authority
ZA
South Africa
Prior art keywords
expression
gene expression
organism
organ
tissue
Prior art date
Application number
ZA200004507A
Inventor
Michael Wayne Graham
Robert Norman Rice
Original Assignee
Benitec Australia Ltd
State Queensland Primary Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25645735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200004507(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from AUPP2492A external-priority patent/AUPP249298A0/en
Priority claimed from AUPP2499A external-priority patent/AUPP249998A0/en
Application filed by Benitec Australia Ltd, State Queensland Primary Ind filed Critical Benitec Australia Ltd
Publication of ZA200004507B publication Critical patent/ZA200004507B/en

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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.
ZA200004507A 1998-03-20 2000-08-30 Control of gene expression. ZA200004507B (en)

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AUPP2492A AUPP249298A0 (en) 1998-03-20 1998-03-20 Synthetic genes and genetic constructs comprising same I
AUPP2499A AUPP249998A0 (en) 1998-03-20 1998-03-20 Gene expression I

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