YU83192A - Postupak za sintezu izosorbid-5-mononitrata - Google Patents

Postupak za sintezu izosorbid-5-mononitrata

Info

Publication number
YU83192A
YU83192A YU83192A YU83192A YU83192A YU 83192 A YU83192 A YU 83192A YU 83192 A YU83192 A YU 83192A YU 83192 A YU83192 A YU 83192A YU 83192 A YU83192 A YU 83192A
Authority
YU
Yugoslavia
Prior art keywords
isosorbid
mononitrate
synthesis
procedure
isosorbide
Prior art date
Application number
YU83192A
Other languages
English (en)
Other versions
YU48455B (sh
Inventor
K.S. Stanković
M. Nikolić
Ž. Ceković
Original Assignee
Farmaceutsko-Hemijska Industrija "Zdravlje"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutsko-Hemijska Industrija "Zdravlje" filed Critical Farmaceutsko-Hemijska Industrija "Zdravlje"
Priority to YU83192A priority Critical patent/YU48455B/sh
Publication of YU83192A publication Critical patent/YU83192A/sh
Publication of YU48455B publication Critical patent/YU48455B/sh

Links

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

POSTUPAK ZA SINTEZU IZOSORBID-5-MONONITRATA - Razvijen je jednostavan i za industrijsku primenu pogodan postupak dobijanja izosorbid-5-monbnitrata reakcijom između izosorbida i anhidrida mravlje kiseline uz refluks u toluolu i prisustvu p-toluolsulfonSke kiseline, a zatim nitrovanjem i hidrolizom do željenog proizvoda, u visokom prinosu i visokog stepena čistoce koji omogućava njegovu primenu kao koronarnog vazodilatatora.
YU83192A 1992-09-11 1992-09-11 Postupak za sintezu izosorbid-5-mononitrata YU48455B (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
YU83192A YU48455B (sh) 1992-09-11 1992-09-11 Postupak za sintezu izosorbid-5-mononitrata

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU83192A YU48455B (sh) 1992-09-11 1992-09-11 Postupak za sintezu izosorbid-5-mononitrata

Publications (2)

Publication Number Publication Date
YU83192A true YU83192A (sh) 1997-09-30
YU48455B YU48455B (sh) 1998-08-14

Family

ID=47566415

Family Applications (1)

Application Number Title Priority Date Filing Date
YU83192A YU48455B (sh) 1992-09-11 1992-09-11 Postupak za sintezu izosorbid-5-mononitrata

Country Status (1)

Country Link
YU (1) YU48455B (sh)

Also Published As

Publication number Publication date
YU48455B (sh) 1998-08-14

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