YU48346B - NEW SULFONAMIDES AND PROCEDURE FOR THEIR PRODUCTION - Google Patents

NEW SULFONAMIDES AND PROCEDURE FOR THEIR PRODUCTION

Info

Publication number
YU48346B
YU48346B YU43792A YU43792A YU48346B YU 48346 B YU48346 B YU 48346B YU 43792 A YU43792 A YU 43792A YU 43792 A YU43792 A YU 43792A YU 48346 B YU48346 B YU 48346B
Authority
YU
Yugoslavia
Prior art keywords
alkoxy
hydrogen
denotes
halogen
trifluoromethyl
Prior art date
Application number
YU43792A
Other languages
Serbo-Croatian (sh)
Other versions
YU43792A (en
Inventor
Burri
Clozel
Fischll
Hirth
Loffler
Ramuz
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Priority to HR931531A priority Critical patent/HRP931531B1/en
Publication of YU43792A publication Critical patent/YU43792A/en
Publication of YU48346B publication Critical patent/YU48346B/en

Links

Abstract

NOVI SULFONAMIDI I POSTUPAK ZA NJIHOVU PROIZVODNJU, naznačeni time, što imaju formulu u kojoj R1 označava vodonik, niži alkil, niži alkoksi, niži alkiltio, halogen ili trifluorometil; R2 označava vodonik, halogen, niži alkoksi, hidroksi niži alkoksi ili trifluorometil; i R3 označava vodonik, hidroksi, halogen, alkiltio, niži alkil, cikloalkil, hidroksi-niži alkil, hidroksi-niži alkoksi, hidroksimino-niži alkil, niži alkenil, okso-niži alkil, trifluorometil, trifluorometoksi, niži alkoksi, niži-alkoksi-niži-alkoksi ili aril-niži-alkoksi; ili R2 i R3 zajedno označavaju butadienil; R4 označava vodonik, niži alkil, aril ili heteroaril; R5 označava vodonik, niži alkanoil, benzoil, heterociklični karbonil ili tetrahidropiran-2-il; R6 označava ostatak formule gde R11 označava halogen, niži alkoksi, niži-alkiltio ili trifluorometil; R12 označava vodonik ili niži alkoksi; R13 označava vodonik, niži alkoksi ili nitro; R14 označava vodonik, halogen, niži alkil, niži alkoksi, niži alkiltio ili nitro ili R13 i R14 zajedno označavaju butadienil; X i Y svaki nezavisno označavaju O, S ili NH; i n označava 2, 3 ili 4; i soli tih jedinjenja. - Prijava sadrži još 2 nezavisna i 6 zavisnih zahteva.NEW SULFONAMIDES AND A PROCEDURE FOR THEIR PRODUCTION, characterized in that they have the formula in which R1 is hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen or trifluoromethyl; R2 is hydrogen, halogen, lower alkoxy, hydroxy lower alkoxy or trifluoromethyl; and R 3 denotes hydrogen, hydroxy, halogen, alkylthio, lower alkyl, cycloalkyl, hydroxy-lower alkyl, hydroxy-lower alkoxy, hydroxymino-lower alkyl, lower alkenyl, oxo-lower alkyl, trifluoromethyl, trifluoromethoxy, lower alkoxy, lower-alkoxy, lower-alkoxy lower-alkoxy or aryl-lower-alkoxy; or R2 and R3 together denote butadienyl; R4 is hydrogen, lower alkyl, aryl or heteroaryl; R5 is hydrogen, lower alkanoyl, benzoyl, heterocyclic carbonyl or tetrahydropyran-2-yl; R 6 denotes a residue of the formula wherein R 11 denotes halogen, lower alkoxy, lower-alkylthio or trifluoromethyl; R12 is hydrogen or lower alkoxy; R 13 denotes hydrogen, lower alkoxy or nitro; R14 denotes hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio or nitro or R13 and R14 together denote butadienyl; X and Y each independently represent O, S or NH; and n denotes 2, 3 or 4; and salts of these compounds. - The application contains 2 more independent and 6 dependent requests.

YU43792A 1991-04-25 1992-04-23 NEW SULFONAMIDES AND PROCEDURE FOR THEIR PRODUCTION YU48346B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HR931531A HRP931531B1 (en) 1991-04-25 1993-10-04 Sulfonamides and their medical use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH124291 1991-04-25

Publications (2)

Publication Number Publication Date
YU43792A YU43792A (en) 1995-01-31
YU48346B true YU48346B (en) 1998-07-10

Family

ID=4205802

Family Applications (1)

Application Number Title Priority Date Filing Date
YU43792A YU48346B (en) 1991-04-25 1992-04-23 NEW SULFONAMIDES AND PROCEDURE FOR THEIR PRODUCTION

Country Status (5)

Country Link
MX (1) MX9201912A (en)
RU (1) RU2083567C1 (en)
UY (1) UY23407A1 (en)
YU (1) YU48346B (en)
ZA (1) ZA922832B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2548044C2 (en) * 2010-07-13 2015-04-10 Астразенека Аб Novel crystalline forms of n-[-2[[(2,3-difluorophenyl)methyl]thio]-6-{[(1r,2s)-2,3-dihydroxy-1-methylpropyl]oxy}-4-pyrimidinyl]-1-azatidine-sulphonamide
RU2461545C1 (en) * 2011-04-20 2012-09-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт "Кристалл" (ФГУП "ГосНИИ "Кристалл") Method of producing 2-methylpyrimidine-4,6-(3h,5h)-dione

Also Published As

Publication number Publication date
YU43792A (en) 1995-01-31
ZA922832B (en) 1993-01-27
UY23407A1 (en) 1992-10-23
RU2083567C1 (en) 1997-07-10
MX9201912A (en) 1992-11-01

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