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Priority claimed from US06/483,052external-prioritypatent/US4766075A/en
Priority to SI8310997ApriorityCriticalpatent/SI8310997B/en
Application filed by Genentech Inc.filedCriticalGenentech Inc.
Publication of YU99783ApublicationCriticalpatent/YU99783A/en
Publication of YU47397BpublicationCriticalpatent/YU47397B/en
Priority to HRP-997/83Aprioritypatent/HRP950158B1/en
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Abstract
POSTUPAK ZA DOBIVANJE AKTIVATORA PLAZMINOGENA LJUDSKOG TKIVA, naznačen time, što obuhvata dobivanje cDNA iz mRNA ekstrahovane iz melanoma ćelije govečeta i izolovanje DNA sekvence koja ima restrikcionu osnovnu strukturnu formulu prikazanu na sl. 4 za predpostavljenu aktivatorsku sekvencu zrelog tkivanog plazminogena i koja kodira 527 amino kiselinski polipeptid koji ima aktivatorsku funkciju humanog tkivnog plazminogena. Prijava sadrži još 2 nezavisna i 8 zavisnih zahteva.A process for obtaining a human tissue plasminogen activator, comprising producing a cDNA from an mRNA extracted from a bovine melanoma cell and isolating a DNA sequence having the restriction basic structural formula shown in FIG. 4 for the putative activator sequence of a mature tissue plasminogen and encoding a 527 amino acid polypeptide having the activator function of human tissue plasminogen. The application contains 2 more independent and 8 dependent requests.
YU99783A1982-05-051983-05-06
PROCEDURE FOR OBTAINING HUMAN TISSUE PLASMINOGEN ACTIVATOR
YU47397B
(en)
METHOD FOR PRODUCING A SOLUTION OF HIGH SPECIFIC VOLUME ACTIVITY FROM A PROTEIN WITH TISSUE PLASMINOGEN ACTIVATOR (T-PA) ACTIVITY, SOLUTION, CONTAINING PROTEIN WITH T-PA ACTIVITY AND USE OF THE SOLUTION AND IN THE HUMAN VITALIZE.