YU45993B - PROCEDURE FOR OBTAINING PREPARATIONS WITH ANTIFLOGISTIC ACTION FROM MATRICARIA CHAMOMILLA - Google Patents

PROCEDURE FOR OBTAINING PREPARATIONS WITH ANTIFLOGISTIC ACTION FROM MATRICARIA CHAMOMILLA

Info

Publication number
YU45993B
YU45993B YU197085A YU197085A YU45993B YU 45993 B YU45993 B YU 45993B YU 197085 A YU197085 A YU 197085A YU 197085 A YU197085 A YU 197085A YU 45993 B YU45993 B YU 45993B
Authority
YU
Yugoslavia
Prior art keywords
alpha
bisabolol
less
bisaboloids
flowers
Prior art date
Application number
YU197085A
Other languages
Serbo-Croatian (sh)
Other versions
YU197085A (en
Inventor
F. Chlodwig
O. Isaac
Original Assignee
Asta Medica Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag. filed Critical Asta Medica Ag.
Publication of YU197085A publication Critical patent/YU197085A/en
Priority to HRP-1970/85A priority Critical patent/HRP920748A2/en
Publication of YU45993B publication Critical patent/YU45993B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

POSTUPAK ZA DOBIJANJE PREPARATA SA ANTIFLOGISTIČKIM DEJSTVOM IZ MATRICARIA CHAMOMILLA. naznačen time, što se iz jedne tetraploidne kamilice, kod koje (-)-alfa-bisabolol predstavalja glavnu komponentu eteričnog ulja, odselektiraju one biljke čiji cvetovi osušeni na 40В° C sadrže najmanje 100 mg% hamazulena, najmanje 200 mg% (-)-alfa-bisabolola i manje od 50 mg% ostalih bisaboloida i što se od tako dobijenih biljaka, u datom slučaju posle daljih koraka selekcije i razmnožavanja, požnju cvetovi u vegetacionom stadijumu u kome je 30-100% cvetova jedne glavice cvetova otvoreno i osušeno na temperaturi od najviše 70 Cda bi se dobio suvi materijal koji sadrži najmanje 30 mg% hamazulena, najmanje 100 mg% (-)-alfa-bisabolola i manje od 50 mg% ostalih bisaboloida i u datom slučaju se od tako dobijenog suvog materijala putem destilacije u prisustvu vode proizvodi eterično ulje koje sadrži najmanje 3,5% humazulena, najmanje 10% (-)-alfa-bisabollola i manje od 10% ostalih bisaboloida ili se putem ekstrakcijesa nižim alkoholima proizvede jedna alkoholna ekstrakcija kamilice koja sadrži najmanje 1,5 mg% hamazulena, najmanje 5,0 mg% (-)-alfa- bisabolola i manje od 10 mg% ostalih hisaboloida. Prijava sadrži 5 zavisnih zahteva.PROCEDURE FOR OBTAINING PREPARATIONS WITH ANTIFLOGISTIC ACTION FROM MATRICARIA CHAMOMILLA. characterized in that from one tetraploid chamomile, in which (-) - alpha-bisabolol is the main component of the essential oil, those plants whose flowers dried at 40V ° C contain at least 100 mg% of chamazulene, at least 200 mg% (-) - alpha-bisabolol and less than 50 mg% of other bisaboloids and that from the plants thus obtained, in a given case after further selection and propagation steps, flowers are harvested in the vegetation stage in which 30-100% of flowers of one flower head are opened and dried at temperature of a maximum of 70 C to obtain a dry material containing at least 30 mg% of hamazulene, at least 100 mg% (-) - alpha-bisabolol and less than 50 mg% of other bisaboloids and optionally from the dry material thus obtained by distillation in the presence of water produces an essential oil containing at least 3,5% humazulene, at least 10% (-) - alpha-bisabollol and less than 10% other bisaboloids, or one alcoholic extraction is produced by extraction with lower alcohols chamomile containing at least 1.5 mg% of hamazulene, at least 5.0 mg% (-) - alpha-bisabolol and less than 10 mg% of other hisaboloids. The application contains 5 dependent requests.

YU197085A 1984-12-19 1985-12-17 PROCEDURE FOR OBTAINING PREPARATIONS WITH ANTIFLOGISTIC ACTION FROM MATRICARIA CHAMOMILLA YU45993B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HRP-1970/85A HRP920748A2 (en) 1984-12-19 1992-10-01 Process for the preparation of a new preparation with antiflogistic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843446217 DE3446217C2 (en) 1984-12-19 1984-12-19 Process for the preparation of a new antiphlogistic agent

Publications (2)

Publication Number Publication Date
YU197085A YU197085A (en) 1988-06-30
YU45993B true YU45993B (en) 1992-12-21

Family

ID=6253138

Family Applications (1)

Application Number Title Priority Date Filing Date
YU197085A YU45993B (en) 1984-12-19 1985-12-17 PROCEDURE FOR OBTAINING PREPARATIONS WITH ANTIFLOGISTIC ACTION FROM MATRICARIA CHAMOMILLA

Country Status (7)

Country Link
CN (1) CN1034631C (en)
BG (1) BG50925A3 (en)
DD (1) DD240135B5 (en)
DE (1) DE3446217C2 (en)
FI (1) FI81007C (en)
PT (1) PT81701B (en)
YU (1) YU45993B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2402802C3 (en) * 1974-01-22 1979-06-13 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Obtaining a chamomile drug with a high content of chamazulene and bisabolol
DE3423207C3 (en) * 1983-06-29 1996-09-26 Asta Medica Ag Process for producing a new type of chamomile (name Manzana)
DE3542756C3 (en) 1984-12-19 1997-09-04 Asta Medica Ag Process for the preparation of a new tetraploid and bisabolol-rich chamomile with improved properties
CN1003201B (en) * 1985-06-12 1989-02-01 三菱雷机株式会社 Switching device for timing switch

Also Published As

Publication number Publication date
YU197085A (en) 1988-06-30
BG50925A3 (en) 1992-12-15
FI81007C (en) 1990-09-10
PT81701B (en) 1988-02-17
CN85108903A (en) 1986-06-10
FI855061A (en) 1986-06-20
DD240135B5 (en) 1994-04-21
CN1034631C (en) 1997-04-23
FI81007B (en) 1990-05-31
DE3446217C2 (en) 1994-05-19
FI855061A0 (en) 1985-12-18
DE3446217A1 (en) 1986-07-10
PT81701A (en) 1986-01-02

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