YU40264B - Process for producing an antibacterial agent, 6-d-(-)-alpha-amino-alpina-(p-acetoxyphenylacetamido) penicillanic acid - Google Patents

Process for producing an antibacterial agent, 6-d-(-)-alpha-amino-alpina-(p-acetoxyphenylacetamido) penicillanic acid

Info

Publication number
YU40264B
YU40264B YU1438/75A YU143875A YU40264B YU 40264 B YU40264 B YU 40264B YU 1438/75 A YU1438/75 A YU 1438/75A YU 143875 A YU143875 A YU 143875A YU 40264 B YU40264 B YU 40264B
Authority
YU
Yugoslavia
Prior art keywords
acetoxyphenylacetamido
alpina
alpha
amino
producing
Prior art date
Application number
YU1438/75A
Other languages
English (en)
Other versions
YU143875A (en
Inventor
D Bouzard
A Weber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2484874A external-priority patent/GB1476981A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of YU143875A publication Critical patent/YU143875A/xx
Publication of YU40264B publication Critical patent/YU40264B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/852—Klebsiella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/873—Proteus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/875—Pseudomonas aeruginosa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/879—Salmonella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/88—Serratia
    • Y10S435/881—Serratia marcescens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/882—Staphylococcus
    • Y10S435/883—Staphylococcus aureus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
YU1438/75A 1974-06-05 1975-06-04 Process for producing an antibacterial agent, 6-d-(-)-alpha-amino-alpina-(p-acetoxyphenylacetamido) penicillanic acid YU40264B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2484874A GB1476981A (en) 1974-06-05 1974-06-05 Substituted penicillanic acids
GB5001674 1974-11-19

Publications (2)

Publication Number Publication Date
YU143875A YU143875A (en) 1982-08-31
YU40264B true YU40264B (en) 1985-12-31

Family

ID=26257327

Family Applications (3)

Application Number Title Priority Date Filing Date
YU1438/75A YU40264B (en) 1974-06-05 1975-06-04 Process for producing an antibacterial agent, 6-d-(-)-alpha-amino-alpina-(p-acetoxyphenylacetamido) penicillanic acid
YU01269/82A YU126982A (en) 1974-06-05 1982-06-10 Process for producing antibacterial agents
YU1260/82A YU40410B (en) 1974-06-05 1982-06-10 Process for producing antibacterial agents 6-d-(-)-alpha-amino-(p-hydroxyphenylacetamido)-penicillanic acid

Family Applications After (2)

Application Number Title Priority Date Filing Date
YU01269/82A YU126982A (en) 1974-06-05 1982-06-10 Process for producing antibacterial agents
YU1260/82A YU40410B (en) 1974-06-05 1982-06-10 Process for producing antibacterial agents 6-d-(-)-alpha-amino-(p-hydroxyphenylacetamido)-penicillanic acid

Country Status (19)

Country Link
US (1) US4053360A (US20030199744A1-20031023-C00003.png)
JP (1) JPS6050795B2 (US20030199744A1-20031023-C00003.png)
AR (1) AR209441A1 (US20030199744A1-20031023-C00003.png)
CA (1) CA1049505A (US20030199744A1-20031023-C00003.png)
CH (2) CH614713A5 (US20030199744A1-20031023-C00003.png)
DD (2) DD126316A5 (US20030199744A1-20031023-C00003.png)
DE (1) DE2524321A1 (US20030199744A1-20031023-C00003.png)
DK (1) DK149129C (US20030199744A1-20031023-C00003.png)
ES (1) ES436565A1 (US20030199744A1-20031023-C00003.png)
FI (1) FI59413C (US20030199744A1-20031023-C00003.png)
FR (2) FR2273536A1 (US20030199744A1-20031023-C00003.png)
IL (2) IL47300A (US20030199744A1-20031023-C00003.png)
IN (1) IN141369B (US20030199744A1-20031023-C00003.png)
NL (3) NL161454C (US20030199744A1-20031023-C00003.png)
NO (2) NO153299C (US20030199744A1-20031023-C00003.png)
OA (1) OA05006A (US20030199744A1-20031023-C00003.png)
PH (1) PH17801A (US20030199744A1-20031023-C00003.png)
SE (2) SE422800B (US20030199744A1-20031023-C00003.png)
YU (3) YU40264B (US20030199744A1-20031023-C00003.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5736298Y2 (US20030199744A1-20031023-C00003.png) * 1977-06-27 1982-08-11
US4248780A (en) * 1979-08-21 1981-02-03 Canada Packers Limited Process for preparing ampicillin
US4540687A (en) * 1981-09-09 1985-09-10 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4582829A (en) * 1981-09-09 1986-04-15 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4457924A (en) * 1981-12-22 1984-07-03 Pfizer, Inc. 1,1-Alkanediol dicarboxylate linked antibacterial agents
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents
US5215891A (en) * 1986-10-15 1993-06-01 Farmitalia Carlo Erba Process for preparing penems
GB8624686D0 (en) * 1986-10-15 1986-11-19 Erba Farmitalia Preparing penems
JPH0344647U (US20030199744A1-20031023-C00003.png) * 1989-09-08 1991-04-25
IE921073A1 (en) * 1991-04-04 1992-10-07 Smithkline Beecham Corp Enzymatic process for the production of cefonicid
US6071712A (en) * 1994-09-19 2000-06-06 Smithkline Beecham Corporation Enzymatic process for the production of cephalosporins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985648A (en) * 1958-10-06 1961-05-23 Doyle Frank Peter Alpha-aminobenzylpenicillins
GB966222A (en) * 1960-04-11 1964-08-06 Nat Res Dev Derivatives of cephalosporin c
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
GB1141293A (en) * 1964-12-23 1969-01-29 Glaxo Lab Ltd Cephemoic acids and derivatives thereof
US3520876A (en) * 1967-11-01 1970-07-21 American Home Prod Process for the preparation of 6-(alpha-aminoacylamino)penicillanic acids
GB1241844A (en) * 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins

Also Published As

Publication number Publication date
DD122251A5 (US20030199744A1-20031023-C00003.png) 1976-09-20
US4053360A (en) 1977-10-11
NL7902824A (nl) 1979-09-28
ES436565A1 (es) 1977-04-01
NL7505302A (nl) 1975-12-09
NO830058L (no) 1975-12-08
DD126316A5 (US20030199744A1-20031023-C00003.png) 1977-07-06
SE434947B (sv) 1984-08-27
SE7506455L (sv) 1975-12-08
YU40410B (en) 1985-12-31
FI59413C (fi) 1981-08-10
NL7506680A (nl) 1975-12-09
NL161454C (nl) 1980-02-15
CH626368A5 (en) 1981-11-13
SE422800B (sv) 1982-03-29
DE2524321A1 (de) 1975-12-18
JPS6050795B2 (ja) 1985-11-11
FI59413B (fi) 1981-04-30
DK149129B (da) 1986-02-03
JPS5111788A (US20030199744A1-20031023-C00003.png) 1976-01-30
FR2273536A1 (fr) 1976-01-02
IL47300A0 (en) 1975-07-28
SE7900773L (sv) 1979-01-29
CA1049505A (en) 1979-02-27
FR2273536B1 (US20030199744A1-20031023-C00003.png) 1978-10-06
PH17801A (en) 1984-12-13
DK149129C (da) 1986-07-14
IN141369B (US20030199744A1-20031023-C00003.png) 1977-02-19
IL47300A (en) 1978-07-31
NO153299B (no) 1985-11-11
AU8050175A (en) 1976-10-28
FI751596A (US20030199744A1-20031023-C00003.png) 1975-12-06
FR2303543A1 (fr) 1976-10-08
NO751596L (US20030199744A1-20031023-C00003.png) 1975-12-08
IL53406A0 (en) 1978-01-31
OA05006A (fr) 1980-12-31
CH614713A5 (en) 1979-12-14
DK193775A (da) 1975-12-06
NO153299C (no) 1986-02-19
FR2303543B1 (US20030199744A1-20031023-C00003.png) 1978-11-10
AR209441A1 (es) 1977-04-29
YU126982A (en) 1982-10-31
YU143875A (en) 1982-08-31

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