IL53406A0 - Enzymatic cleavage of alpha-amino-alpha-(rho-acetoxyphenylacetamido)penicillanic acid - Google Patents

Enzymatic cleavage of alpha-amino-alpha-(rho-acetoxyphenylacetamido)penicillanic acid

Info

Publication number
IL53406A0
IL53406A0 IL7753406A IL5340677A IL53406A0 IL 53406 A0 IL53406 A0 IL 53406A0 IL 7753406 A IL7753406 A IL 7753406A IL 5340677 A IL5340677 A IL 5340677A IL 53406 A0 IL53406 A0 IL 53406A0
Authority
IL
Israel
Prior art keywords
alpha
acetoxyphenylacetamido
rho
amino
enzymatic cleavage
Prior art date
Application number
IL7753406A
Other languages
English (en)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2484874A external-priority patent/GB1476981A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IL53406A0 publication Critical patent/IL53406A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/852—Klebsiella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/873—Proteus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/875—Pseudomonas aeruginosa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/879—Salmonella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/88—Serratia
    • Y10S435/881—Serratia marcescens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/882—Staphylococcus
    • Y10S435/883—Staphylococcus aureus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL7753406A 1974-06-05 1977-11-16 Enzymatic cleavage of alpha-amino-alpha-(rho-acetoxyphenylacetamido)penicillanic acid IL53406A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2484874A GB1476981A (en) 1974-06-05 1974-06-05 Substituted penicillanic acids
GB5001674 1974-11-19

Publications (1)

Publication Number Publication Date
IL53406A0 true IL53406A0 (en) 1978-01-31

Family

ID=26257327

Family Applications (2)

Application Number Title Priority Date Filing Date
IL7547300A IL47300A (en) 1974-06-05 1975-05-14 -amino- -(p-acetoxyphenyl)acetamido-penicilanic acid and salts thereof, their preparation and pharmaceutical composions containing them
IL7753406A IL53406A0 (en) 1974-06-05 1977-11-16 Enzymatic cleavage of alpha-amino-alpha-(rho-acetoxyphenylacetamido)penicillanic acid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL7547300A IL47300A (en) 1974-06-05 1975-05-14 -amino- -(p-acetoxyphenyl)acetamido-penicilanic acid and salts thereof, their preparation and pharmaceutical composions containing them

Country Status (19)

Country Link
US (1) US4053360A (xx)
JP (1) JPS6050795B2 (xx)
AR (1) AR209441A1 (xx)
CA (1) CA1049505A (xx)
CH (2) CH614713A5 (xx)
DD (2) DD122251A5 (xx)
DE (1) DE2524321A1 (xx)
DK (1) DK149129C (xx)
ES (1) ES436565A1 (xx)
FI (1) FI59413C (xx)
FR (2) FR2273536A1 (xx)
IL (2) IL47300A (xx)
IN (1) IN141369B (xx)
NL (3) NL161454C (xx)
NO (2) NO153299C (xx)
OA (1) OA05006A (xx)
PH (1) PH17801A (xx)
SE (2) SE422800B (xx)
YU (3) YU40264B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5736298Y2 (xx) * 1977-06-27 1982-08-11
US4248780A (en) * 1979-08-21 1981-02-03 Canada Packers Limited Process for preparing ampicillin
US4582829A (en) * 1981-09-09 1986-04-15 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4540687A (en) * 1981-09-09 1985-09-10 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents
US4457924A (en) * 1981-12-22 1984-07-03 Pfizer, Inc. 1,1-Alkanediol dicarboxylate linked antibacterial agents
US5215891A (en) * 1986-10-15 1993-06-01 Farmitalia Carlo Erba Process for preparing penems
GB8624686D0 (en) * 1986-10-15 1986-11-19 Erba Farmitalia Preparing penems
JPH0344647U (xx) * 1989-09-08 1991-04-25
IE921073A1 (en) * 1991-04-04 1992-10-07 Smithkline Beecham Corp Enzymatic process for the production of cefonicid
US6071712A (en) * 1994-09-19 2000-06-06 Smithkline Beecham Corporation Enzymatic process for the production of cephalosporins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985648A (en) * 1958-10-06 1961-05-23 Doyle Frank Peter Alpha-aminobenzylpenicillins
GB966222A (en) * 1960-04-11 1964-08-06 Nat Res Dev Derivatives of cephalosporin c
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
GB1141293A (en) * 1964-12-23 1969-01-29 Glaxo Lab Ltd Cephemoic acids and derivatives thereof
US3520876A (en) * 1967-11-01 1970-07-21 American Home Prod Process for the preparation of 6-(alpha-aminoacylamino)penicillanic acids
GB1241844A (en) * 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins

Also Published As

Publication number Publication date
JPS6050795B2 (ja) 1985-11-11
SE422800B (sv) 1982-03-29
SE7900773L (sv) 1979-01-29
FR2273536A1 (fr) 1976-01-02
FI751596A (xx) 1975-12-06
ES436565A1 (es) 1977-04-01
CA1049505A (en) 1979-02-27
NO830058L (no) 1975-12-08
JPS5111788A (xx) 1976-01-30
DK193775A (da) 1975-12-06
SE7506455L (sv) 1975-12-08
NL7506680A (nl) 1975-12-09
DD126316A5 (xx) 1977-07-06
PH17801A (en) 1984-12-13
SE434947B (sv) 1984-08-27
FI59413B (fi) 1981-04-30
IN141369B (xx) 1977-02-19
DE2524321A1 (de) 1975-12-18
NL7505302A (nl) 1975-12-09
YU40410B (en) 1985-12-31
FR2273536B1 (xx) 1978-10-06
AU8050175A (en) 1976-10-28
FR2303543B1 (xx) 1978-11-10
NO751596L (xx) 1975-12-08
NL7902824A (nl) 1979-09-28
OA05006A (fr) 1980-12-31
IL47300A (en) 1978-07-31
CH614713A5 (en) 1979-12-14
IL47300A0 (en) 1975-07-28
YU40264B (en) 1985-12-31
DD122251A5 (xx) 1976-09-20
YU126982A (en) 1982-10-31
YU143875A (en) 1982-08-31
FR2303543A1 (fr) 1976-10-08
DK149129B (da) 1986-02-03
US4053360A (en) 1977-10-11
NO153299B (no) 1985-11-11
FI59413C (fi) 1981-08-10
NO153299C (no) 1986-02-19
AR209441A1 (es) 1977-04-29
NL161454C (nl) 1980-02-15
CH626368A5 (en) 1981-11-13
DK149129C (da) 1986-07-14

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