YU314879A - Process for obtaining ketal or thioketal derivatives of mercaptoacyl-proline - Google Patents

Process for obtaining ketal or thioketal derivatives of mercaptoacyl-proline

Info

Publication number
YU314879A
YU314879A YU03148/79A YU314879A YU314879A YU 314879 A YU314879 A YU 314879A YU 03148/79 A YU03148/79 A YU 03148/79A YU 314879 A YU314879 A YU 314879A YU 314879 A YU314879 A YU 314879A
Authority
YU
Yugoslavia
Prior art keywords
mercaptoacyl
ketal
proline
obtaining
thioketal
Prior art date
Application number
YU03148/79A
Inventor
J Krapcho
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of YU314879A publication Critical patent/YU314879A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
YU03148/79A 1978-12-22 1979-12-21 Process for obtaining ketal or thioketal derivatives of mercaptoacyl-proline YU314879A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97231478A 1978-12-22 1978-12-22

Publications (1)

Publication Number Publication Date
YU314879A true YU314879A (en) 1983-04-30

Family

ID=25519507

Family Applications (1)

Application Number Title Priority Date Filing Date
YU03148/79A YU314879A (en) 1978-12-22 1979-12-21 Process for obtaining ketal or thioketal derivatives of mercaptoacyl-proline

Country Status (31)

Country Link
JP (1) JPS5594357A (en)
AT (1) AT374174B (en)
AU (1) AU533149B2 (en)
BE (1) BE880815A (en)
CA (1) CA1132985A (en)
CH (1) CH642065A5 (en)
CS (1) CS215036B2 (en)
DD (1) DD148338A5 (en)
DE (1) DE2951200A1 (en)
DK (1) DK159115C (en)
ES (2) ES8102094A1 (en)
FI (1) FI70886C (en)
FR (1) FR2444669A1 (en)
GB (1) GB2039478B (en)
GR (1) GR78384B (en)
HK (1) HK15684A (en)
HU (1) HU179644B (en)
IE (1) IE49321B1 (en)
IL (1) IL58930A (en)
IT (1) IT1126841B (en)
LU (1) LU82023A1 (en)
NL (1) NL7909246A (en)
NO (1) NO153569C (en)
NZ (1) NZ192449A (en)
PH (1) PH19213A (en)
PL (1) PL133414B1 (en)
PT (1) PT70620A (en)
SE (1) SE451839B (en)
SU (1) SU1115668A3 (en)
YU (1) YU314879A (en)
ZA (1) ZA796720B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455585A1 (en) * 1979-05-04 1980-11-28 Ono Pharmaceutical Co OXOAMINOACID DERIVATIVES, MANUFACTURING METHOD AND PHARMACEUTICAL COMPOSITION
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
US4356182A (en) * 1979-10-22 1982-10-26 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
US4284624A (en) 1980-05-02 1981-08-18 E. R. Squibb & Sons, Inc. Mixed disulfides
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
US4311705A (en) * 1980-10-06 1982-01-19 E. R. Squibb & Sons, Inc. Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
US4374131A (en) 1981-04-27 1983-02-15 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinyl-alkanoyl compounds
US4416831A (en) 1981-04-27 1983-11-22 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinylalkanoyl compounds
US4381297A (en) 1981-05-04 1983-04-26 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4416833A (en) 1981-05-04 1983-11-22 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4555506A (en) * 1981-12-24 1985-11-26 E. R. Squibb & Sons, Inc. Phosphorus containing compounds and use as hypotensives
US4560680A (en) * 1982-03-15 1985-12-24 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4452791A (en) * 1982-03-15 1984-06-05 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
CA1258853A (en) * 1982-04-30 1989-08-29 Rudiger D. Haugwitz Substituted 4-phenoxy prolines
US4452790A (en) * 1982-06-23 1984-06-05 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4616005A (en) * 1982-06-23 1986-10-07 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4703043A (en) * 1982-06-23 1987-10-27 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive
US4567166A (en) * 1982-07-14 1986-01-28 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinylalkanoyl compounds useful for treating hypertension
US4709046A (en) * 1983-05-09 1987-11-24 E. R. Squibb & Sons, Inc. Acylmercaptoalkanoyl and mercaptoalkanoyl spiro compounds
CA2021409A1 (en) * 1989-08-21 1991-02-22 Donald S. Karanewsky Phosphonate substituted amino or imino acids useful as antihypertensives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4091024A (en) * 1976-12-03 1978-05-23 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives
IT7851510A0 (en) * 1977-10-28 1978-10-16 Sandoz Ag AMIDES OF CYCLIC AMINO ACIDS THEIR PREPARATION AND THEIR APPLICATION AS MEDICINES
PH15381A (en) * 1978-02-21 1982-12-17 Squibb & Sons Inc Halogen substituted mercaptoacylamino acids
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines

Also Published As

Publication number Publication date
ZA796720B (en) 1980-11-26
AT374174B (en) 1984-03-26
IT1126841B (en) 1986-05-21
ES487180A0 (en) 1980-12-16
IL58930A (en) 1983-07-31
GB2039478A (en) 1980-08-13
IL58930A0 (en) 1980-03-31
SE7910550L (en) 1980-06-23
FI794027A (en) 1980-06-23
DK550079A (en) 1980-06-23
FR2444669A1 (en) 1980-07-18
HU179644B (en) 1982-11-29
AU5371479A (en) 1980-06-26
PL133414B1 (en) 1985-05-31
AU533149B2 (en) 1983-11-03
CA1132985A (en) 1982-10-05
CH642065A5 (en) 1984-03-30
FR2444669B1 (en) 1983-06-03
ATA805479A (en) 1983-08-15
FI70886C (en) 1986-10-27
IE792468L (en) 1980-06-22
HK15684A (en) 1984-03-02
SU1115668A3 (en) 1984-09-23
GB2039478B (en) 1983-02-16
NO794181L (en) 1980-06-24
DD148338A5 (en) 1981-05-20
PL220609A1 (en) 1980-12-01
IT7951167A0 (en) 1979-12-21
NO153569C (en) 1986-05-21
NL7909246A (en) 1980-06-24
PH19213A (en) 1986-02-04
NO153569B (en) 1986-01-06
ES488752A0 (en) 1981-02-16
BE880815A (en) 1980-06-23
ES8102094A1 (en) 1980-12-16
CS215036B2 (en) 1982-06-25
ES8103039A1 (en) 1981-02-16
LU82023A1 (en) 1980-04-23
GR78384B (en) 1984-09-26
NZ192449A (en) 1984-05-31
JPS5594357A (en) 1980-07-17
SE451839B (en) 1987-11-02
IE49321B1 (en) 1985-09-18
PT70620A (en) 1980-01-01
DK159115C (en) 1991-02-11
DK159115B (en) 1990-09-03
FI70886B (en) 1986-07-18
DE2951200A1 (en) 1980-07-10

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