ES488752A0 - A PROCEDURE FOR PREPARING MERCAPTOACIL-PROLINAS CETALIC AND THIOCEALIC DERIVATIVES - Google Patents
A PROCEDURE FOR PREPARING MERCAPTOACIL-PROLINAS CETALIC AND THIOCEALIC DERIVATIVESInfo
- Publication number
- ES488752A0 ES488752A0 ES488752A ES488752A ES488752A0 ES 488752 A0 ES488752 A0 ES 488752A0 ES 488752 A ES488752 A ES 488752A ES 488752 A ES488752 A ES 488752A ES 488752 A0 ES488752 A0 ES 488752A0
- Authority
- ES
- Spain
- Prior art keywords
- thiocealic
- prolinas
- mercaptoacil
- cetalic
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/10—Spiro-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97231478A | 1978-12-22 | 1978-12-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES488752A0 true ES488752A0 (en) | 1981-02-16 |
ES8103039A1 ES8103039A1 (en) | 1981-02-16 |
Family
ID=25519507
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487180A Expired ES8102094A1 (en) | 1978-12-22 | 1979-12-21 | Derivatives of mercaptoacyl pyrrolidines or piperidines |
ES488752A Expired ES8103039A1 (en) | 1978-12-22 | 1980-02-20 | Derivatives of mercaptoacyl pyrrolidines or piperidines |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487180A Expired ES8102094A1 (en) | 1978-12-22 | 1979-12-21 | Derivatives of mercaptoacyl pyrrolidines or piperidines |
Country Status (31)
Country | Link |
---|---|
JP (1) | JPS5594357A (en) |
AT (1) | AT374174B (en) |
AU (1) | AU533149B2 (en) |
BE (1) | BE880815A (en) |
CA (1) | CA1132985A (en) |
CH (1) | CH642065A5 (en) |
CS (1) | CS215036B2 (en) |
DD (1) | DD148338A5 (en) |
DE (1) | DE2951200A1 (en) |
DK (1) | DK159115C (en) |
ES (2) | ES8102094A1 (en) |
FI (1) | FI70886C (en) |
FR (1) | FR2444669A1 (en) |
GB (1) | GB2039478B (en) |
GR (1) | GR78384B (en) |
HK (1) | HK15684A (en) |
HU (1) | HU179644B (en) |
IE (1) | IE49321B1 (en) |
IL (1) | IL58930A (en) |
IT (1) | IT1126841B (en) |
LU (1) | LU82023A1 (en) |
NL (1) | NL7909246A (en) |
NO (1) | NO153569C (en) |
NZ (1) | NZ192449A (en) |
PH (1) | PH19213A (en) |
PL (1) | PL133414B1 (en) |
PT (1) | PT70620A (en) |
SE (1) | SE451839B (en) |
SU (1) | SU1115668A3 (en) |
YU (1) | YU314879A (en) |
ZA (1) | ZA796720B (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2455585A1 (en) * | 1979-05-04 | 1980-11-28 | Ono Pharmaceutical Co | OXOAMINOACID DERIVATIVES, MANUFACTURING METHOD AND PHARMACEUTICAL COMPOSITION |
US4288368A (en) * | 1979-07-30 | 1981-09-08 | E. R. Squibb & Sons, Inc. | Dithioacylproline derivatives |
US4291040A (en) * | 1979-10-22 | 1981-09-22 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines |
US4356182A (en) * | 1979-10-22 | 1982-10-26 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of 4-disubstituted prolines |
HU184082B (en) * | 1979-12-29 | 1984-06-28 | Egyt Gyogyszervegyeszeti Gyar | Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid |
US4284624A (en) | 1980-05-02 | 1981-08-18 | E. R. Squibb & Sons, Inc. | Mixed disulfides |
US4316905A (en) * | 1980-07-01 | 1982-02-23 | E. R. Squibb & Sons, Inc. | Mercaptoacyl derivatives of various 4-substituted prolines |
US4311705A (en) * | 1980-10-06 | 1982-01-19 | E. R. Squibb & Sons, Inc. | Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines |
US4462943A (en) * | 1980-11-24 | 1984-07-31 | E. R. Squibb & Sons, Inc. | Carboxyalkyl amino acid derivatives of various substituted prolines |
US4416831A (en) | 1981-04-27 | 1983-11-22 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinylalkanoyl compounds |
US4374131A (en) | 1981-04-27 | 1983-02-15 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinyl-alkanoyl compounds |
US4416833A (en) | 1981-05-04 | 1983-11-22 | E. R. Squibb & Sons, Inc. | Substituted carbonyl phosphinyl-alkanoyl compounds |
US4381297A (en) | 1981-05-04 | 1983-04-26 | E. R. Squibb & Sons, Inc. | Substituted carbonyl phosphinyl-alkanoyl compounds |
US4555506A (en) * | 1981-12-24 | 1985-11-26 | E. R. Squibb & Sons, Inc. | Phosphorus containing compounds and use as hypotensives |
US4452791A (en) * | 1982-03-15 | 1984-06-05 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
US4560680A (en) * | 1982-03-15 | 1985-12-24 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
CA1258853A (en) * | 1982-04-30 | 1989-08-29 | Rudiger D. Haugwitz | Substituted 4-phenoxy prolines |
US4703043A (en) * | 1982-06-23 | 1987-10-27 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive |
US4452790A (en) * | 1982-06-23 | 1984-06-05 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives |
US4616005A (en) * | 1982-06-23 | 1986-10-07 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives |
US4567166A (en) * | 1982-07-14 | 1986-01-28 | E. R. Squibb & Sons, Inc. | Amino and substituted amino phosphinylalkanoyl compounds useful for treating hypertension |
US4709046A (en) * | 1983-05-09 | 1987-11-24 | E. R. Squibb & Sons, Inc. | Acylmercaptoalkanoyl and mercaptoalkanoyl spiro compounds |
CA2021409A1 (en) * | 1989-08-21 | 1991-02-22 | Donald S. Karanewsky | Phosphonate substituted amino or imino acids useful as antihypertensives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
US4091024A (en) * | 1976-12-03 | 1978-05-23 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
IT7851510A0 (en) * | 1977-10-28 | 1978-10-16 | Sandoz Ag | AMIDES OF CYCLIC AMINO ACIDS THEIR PREPARATION AND THEIR APPLICATION AS MEDICINES |
PH15381A (en) * | 1978-02-21 | 1982-12-17 | Squibb & Sons Inc | Halogen substituted mercaptoacylamino acids |
CA1144930A (en) * | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
-
1979
- 1979-12-07 CA CA341,486A patent/CA1132985A/en not_active Expired
- 1979-12-11 ZA ZA00796720A patent/ZA796720B/en unknown
- 1979-12-11 AU AU53714/79A patent/AU533149B2/en not_active Ceased
- 1979-12-12 IL IL58930A patent/IL58930A/en unknown
- 1979-12-13 GR GR60746A patent/GR78384B/el unknown
- 1979-12-13 GB GB7942991A patent/GB2039478B/en not_active Expired
- 1979-12-17 CS CS798891A patent/CS215036B2/en unknown
- 1979-12-18 NZ NZ192449A patent/NZ192449A/en unknown
- 1979-12-19 FR FR7931132A patent/FR2444669A1/en active Granted
- 1979-12-19 DE DE19792951200 patent/DE2951200A1/en not_active Ceased
- 1979-12-19 IE IE2468/79A patent/IE49321B1/en unknown
- 1979-12-19 PH PH23434A patent/PH19213A/en unknown
- 1979-12-19 NO NO794181A patent/NO153569C/en unknown
- 1979-12-20 SE SE7910550A patent/SE451839B/en not_active IP Right Cessation
- 1979-12-20 AT AT0805479A patent/AT374174B/en active
- 1979-12-20 CH CH1133979A patent/CH642065A5/en not_active IP Right Cessation
- 1979-12-21 ES ES487180A patent/ES8102094A1/en not_active Expired
- 1979-12-21 LU LU82023A patent/LU82023A1/en unknown
- 1979-12-21 FI FI794027A patent/FI70886C/en not_active IP Right Cessation
- 1979-12-21 DK DK550079A patent/DK159115C/en not_active IP Right Cessation
- 1979-12-21 HU HU79SU1047A patent/HU179644B/en not_active IP Right Cessation
- 1979-12-21 NL NL7909246A patent/NL7909246A/en not_active Application Discontinuation
- 1979-12-21 SU SU792860149A patent/SU1115668A3/en active
- 1979-12-21 YU YU03148/79A patent/YU314879A/en unknown
- 1979-12-21 DD DD79218061A patent/DD148338A5/en not_active IP Right Cessation
- 1979-12-21 PT PT70620A patent/PT70620A/en unknown
- 1979-12-21 PL PL1979220609A patent/PL133414B1/en unknown
- 1979-12-21 BE BE0/198709A patent/BE880815A/en not_active IP Right Cessation
- 1979-12-21 IT IT51167/79A patent/IT1126841B/en active
- 1979-12-22 JP JP16747179A patent/JPS5594357A/en active Pending
-
1980
- 1980-02-20 ES ES488752A patent/ES8103039A1/en not_active Expired
-
1984
- 1984-02-23 HK HK156/84A patent/HK15684A/en unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960401 |