YU18701A - Tretiranje depresije - Google Patents

Tretiranje depresije

Info

Publication number
YU18701A
YU18701A YU18701A YU18701A YU18701A YU 18701 A YU18701 A YU 18701A YU 18701 A YU18701 A YU 18701A YU 18701 A YU18701 A YU 18701A YU 18701 A YU18701 A YU 18701A
Authority
YU
Yugoslavia
Prior art keywords
depression
treatment
isobenzo
spiro
fluorophenyl
Prior art date
Application number
YU18701A
Other languages
English (en)
Inventor
Connie Sanchez
Original Assignee
H. Lundbeck A/S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S. filed Critical H. Lundbeck A/S.
Publication of YU18701A publication Critical patent/YU18701A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Opisano je jedinjenje 1'-[4-[1-(4-fluorofenil)-1H-indol-3-il]-1-butil]-spiro[izobenzofuran-1(3H),4'-piperidin] koje je aktivno u odredjenim modelima za antidepresivne efekte i koje je korisno za pripremanje leka za tretiranje depresije ili bolesti koje su u vezi sa depresivnim simptomima.[The compound 1'-[4-[1-(4-fluorophenyl)-1i(H)-indole-3-yl]-1-butyl]-spiro[isobenzo-furan-1(3i(H),4'-piperidine] is active in models predictive of antidepressant effects and is useful for the preparation of a medicament for the treatment of depression or diseases associated with depressive symptoms.
YU18701A 1998-09-15 1999-09-14 Tretiranje depresije YU18701A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA199801163 1998-09-15

Publications (1)

Publication Number Publication Date
YU18701A true YU18701A (sh) 2003-07-07

Family

ID=8101704

Family Applications (1)

Application Number Title Priority Date Filing Date
YU18701A YU18701A (sh) 1998-09-15 1999-09-14 Tretiranje depresije

Country Status (25)

Country Link
US (1) US6358966B2 (sh)
EP (1) EP1121122A1 (sh)
JP (1) JP2002524515A (sh)
KR (1) KR20010075120A (sh)
CN (1) CN1317969A (sh)
AR (1) AR021805A1 (sh)
AU (1) AU5617499A (sh)
BG (1) BG105378A (sh)
BR (1) BR9913964A (sh)
CA (1) CA2343761A1 (sh)
CZ (1) CZ2001946A3 (sh)
EA (1) EA200100355A1 (sh)
HK (1) HK1040922A1 (sh)
HR (1) HRP20010191A2 (sh)
HU (1) HUP0103568A3 (sh)
ID (1) ID29414A (sh)
IL (1) IL141880A0 (sh)
IS (1) IS5873A (sh)
NO (1) NO20011268L (sh)
PL (1) PL346528A1 (sh)
SK (1) SK3502001A3 (sh)
TR (1) TR200100767T2 (sh)
WO (1) WO2000015225A1 (sh)
YU (1) YU18701A (sh)
ZA (1) ZA200101910B (sh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001279607A1 (en) * 2000-08-15 2002-02-25 H. Lundbeck, A/S Pharmaceutical composition containing 1'-(4-(1-(4-fluorophenyl)-1h-indole-3-yl) -1-butyl)-spiro(isobenzofuran-1(3h),4'-piperidine)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
PL342989A1 (en) * 1998-04-07 2001-07-16 Lundbeck & Co As H Treatment of panic attacks

Also Published As

Publication number Publication date
HK1040922A1 (zh) 2002-06-28
WO2000015225A1 (en) 2000-03-23
HUP0103568A2 (hu) 2002-01-28
KR20010075120A (ko) 2001-08-09
IS5873A (is) 2001-02-28
US6358966B2 (en) 2002-03-19
CZ2001946A3 (cs) 2001-09-12
HRP20010191A2 (en) 2002-04-30
SK3502001A3 (en) 2001-12-03
IL141880A0 (en) 2002-03-10
PL346528A1 (en) 2002-02-11
EP1121122A1 (en) 2001-08-08
EA200100355A1 (ru) 2001-08-27
BG105378A (bg) 2001-12-29
HUP0103568A3 (en) 2003-05-28
TR200100767T2 (tr) 2001-07-23
BR9913964A (pt) 2001-07-03
AR021805A1 (es) 2002-08-07
US20010020027A1 (en) 2001-09-06
CN1317969A (zh) 2001-10-17
NO20011268L (no) 2001-05-15
NO20011268D0 (no) 2001-03-13
JP2002524515A (ja) 2002-08-06
ID29414A (id) 2001-08-30
AU5617499A (en) 2000-04-03
ZA200101910B (en) 2001-09-11
CA2343761A1 (en) 2000-03-23

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