YU14493A - SULFONAMIDOKARBOKSIAMIDI - Google Patents
SULFONAMIDOKARBOKSIAMIDIInfo
- Publication number
- YU14493A YU14493A YU14493A YU14493A YU14493A YU 14493 A YU14493 A YU 14493A YU 14493 A YU14493 A YU 14493A YU 14493 A YU14493 A YU 14493A YU 14493 A YU14493 A YU 14493A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- group
- denotes
- formula
- alkyl
- ch2ch
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
SULFONAMIDOKARBOKSIAMIDI, novi sulfonamidokarboksamidi formule u kojoj označavaju A aril, heteroaril, heterociklil, alkil ili cikloalkil, M grupu formule M1, ili, ako X oznaCava grupu X2, ili X oznaCava grupu X1 najmanje jedan od simbola R1, R2 i Q a Q je različit od H, i/ili ako A označava alkil ili cikloalkil, onda M takođe može da označava grupu jedne od formula M2 do M8, CH2CH(NH(CO)i.2R7)- (M3) -CH2CH(NHC(0)0-benzil)r (M4) =CH(CH2)i-2R7 (M3) =CHCH2C(0)R8 (M6) =CHCH2NH(CO)i.2R7 (M7) =CHĆH2NHC(0)0-benzU (M8) Q H, niži alldl ili niži alkU (OH, COOH ili COO-niži alkil), X grupu formule X1 ili X2. Y H ili, ako X označava grupu X2 ili ako X označava X1, u kojoj je najmanje jedan od simbola R1 i R2 različit od H, onda Y takođe može da označava CH2COOH ili SO2-A', kao i njihovi hidrati ili solvati sprečavaju agregaciju krvnih pločica koja je indukovana trombinom i zgrušavanje fibrinogena u krvnoj plazmi. Oni se dobivaju amidiniranjem ciklične amino grupe koja stoji na mestu grupe X ili stvaranjem amida C(0)N(Q).SULPHONAMIDOCARBOXYAMIDES, novel sulfonamidocarboxamides of the formula wherein A represents aryl, heteroaryl, heterocyclyl, alkyl or cycloalkyl, M a group of formula M1, or, if X represents a group X2, or X represents a group X1 is at least one of the symbols Q1, R2 of H, and / or if A denotes alkyl or cycloalkyl, then M may also denote a group of one of the formulas M2 to M8, CH2CH (NH (CO) i.2R7) - (M3) -CH2CH (NHC (O) O- benzyl) r (M4) = CH (CH2) i-2R7 (M3) = CHCH2C (O) R8 (M6) = CHCH2NH (CO) i.2R7 (M7) = CH2H2NHC (O) O-benzyl (M8) QH, lower alld1 or lower alkyl (OH, COOH or COO-lower alkyl), an X group of formula X1 or X2. YH or, if X denotes a group X2 or if X denotes X1, in which at least one of the symbols R1 and R2 is different from H, then Y may also denote CH2COOH or SO2-A ', and their hydrates or solvates prevent the aggregation of blood platelet-induced platelet and clotting of fibrinogen in blood plasma. They are obtained by amidination of a cyclic amino group standing in place of group X or by formation of amide C (O) N (Q).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH72892 | 1992-03-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU14493A true YU14493A (en) | 1997-01-08 |
Family
ID=4193803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU14493A YU14493A (en) | 1992-03-06 | 1993-03-03 | SULFONAMIDOKARBOKSIAMIDI |
Country Status (10)
Country | Link |
---|---|
KR (1) | KR100274422B1 (en) |
BR (1) | BR9300753A (en) |
HR (1) | HRP930266A2 (en) |
MX (1) | MX9301155A (en) |
PL (1) | PL173030B1 (en) |
SG (1) | SG48063A1 (en) |
SI (1) | SI9300104A (en) |
SK (1) | SK14893A3 (en) |
YU (1) | YU14493A (en) |
ZA (1) | ZA931403B (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201303B (en) * | 1990-07-05 | 1993-03-01 | Hoffmann La Roche |
-
1993
- 1993-02-22 SG SG1996006774A patent/SG48063A1/en unknown
- 1993-02-26 ZA ZA931403A patent/ZA931403B/en unknown
- 1993-03-01 SK SK148-93A patent/SK14893A3/en unknown
- 1993-03-02 MX MX9301155A patent/MX9301155A/en unknown
- 1993-03-03 YU YU14493A patent/YU14493A/en unknown
- 1993-03-04 BR BR9300753A patent/BR9300753A/en not_active Application Discontinuation
- 1993-03-05 SI SI19939300104A patent/SI9300104A/en unknown
- 1993-03-05 PL PL93297960A patent/PL173030B1/en unknown
- 1993-03-05 KR KR1019930003315A patent/KR100274422B1/en not_active IP Right Cessation
- 1993-03-05 HR HR930266A patent/HRP930266A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR9300753A (en) | 1993-09-08 |
KR100274422B1 (en) | 2000-12-15 |
SI9300104A (en) | 1993-09-30 |
MX9301155A (en) | 1993-09-01 |
HRP930266A2 (en) | 1996-04-30 |
ZA931403B (en) | 1993-09-06 |
SK14893A3 (en) | 1993-11-10 |
PL173030B1 (en) | 1998-01-30 |
KR930019627A (en) | 1993-10-18 |
PL297960A1 (en) | 1993-09-20 |
SG48063A1 (en) | 1998-04-17 |
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