ECSP951529A - PHARMACEUTICAL COMPOUNDS - Google Patents

PHARMACEUTICAL COMPOUNDS

Info

Publication number
ECSP951529A
ECSP951529A ECSP951529A ECSP951529A EC SP951529 A ECSP951529 A EC SP951529A EC SP951529 A ECSP951529 A EC SP951529A EC SP951529 A ECSP951529 A EC SP951529A
Authority
EC
Ecuador
Prior art keywords
optionally substituted
alkyl
phenyl
hydrogen
naphthyl
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Jeremy Gilmore
Peter Thaddeus Gallagher
Martin Victor Miles
William Martin Owton
Colin Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP951529 priority Critical patent/ECSP951529A/en
Publication of ECSP951529A publication Critical patent/ECSP951529A/en

Links

Abstract

Un compuesto de la fórmula: en la cual R1 y R7 son cada uno halo, trifluorometilo, alquilo C1-6, alcoxi C1-6, fenilo opcionalmente sustituido, naftilo opcionalmente sustituido o heteroarilo opcionalmente sustituido, R2 y R3 son cada uno hidrógeno o alquilo C1-6, R4 y R5 son cada uno hidrógeno, halo, trifluorometilo, alquilo C1-6, alcoxi C1-6, fenilo opcionalmente sustituido, naftilo opcionalmente sustituido o heteroarilo opcionalmente sustituido, R6 es hidrógeno, alquilo C1-6, fenilo opcionalmente sustituido, naftilo opcionalmente sustituido, heteroarilo opcionalmente sustituido, fenilo C1-6 alquilo opcionalmente sustituido o -CO2R8 donde R8 es un grupo éster, m y p son cada uno 0,1,2,3, o 4, n es 1,2,3 o 4; Z es Donde R9 y R10 son cada uno hidrógeno, alquilo C1-6 o fenilo C1-6 alquilo opcionalmente sustituido, X es oxígeno o azufre y Y es Donde R11 y R12 son cada uno hidrógeno, alquilo C1-6, trifluorometilo, fenilo opcionalmente sustituido, naftilo opcionalmente sustituido o heteroarilo opcionalmente sustituido; y sales y solvatos de los mismos.A compound of the formula: in which R1 and R7 are each halo, trifluoromethyl, C1-6 alkyl, C1-6 alkoxy, optionally substituted phenyl, optionally substituted naphthyl or optionally substituted heteroaryl, R2 and R3 are each hydrogen or alkyl C1-6, R4 and R5 are each hydrogen, halo, trifluoromethyl, C1-6 alkyl, C1-6 alkoxy, optionally substituted phenyl, optionally substituted naphthyl or optionally substituted heteroaryl, R6 is hydrogen, C1-6 alkyl, optionally substituted phenyl , optionally substituted naphthyl, optionally substituted heteroaryl, C1-6 phenyl optionally substituted alkyl or -CO2R8 where R8 is an ester group, m and p are each 0,1,2,3, or 4, n is 1,2,3 or 4 ; Z is Where R9 and R10 are each hydrogen, optionally substituted C1-6 alkyl or phenyl C1-6 alkyl, X is oxygen or sulfur and Y is Where R11 and R12 are each hydrogen, optionally C1-6 alkyl, trifluoromethyl, phenyl substituted, optionally substituted naphthyl or optionally substituted heteroaryl; and salts and solvates thereof.

ECSP951529 1995-09-05 1995-09-05 PHARMACEUTICAL COMPOUNDS ECSP951529A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP951529 ECSP951529A (en) 1995-09-05 1995-09-05 PHARMACEUTICAL COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP951529 ECSP951529A (en) 1995-09-05 1995-09-05 PHARMACEUTICAL COMPOUNDS

Publications (1)

Publication Number Publication Date
ECSP951529A true ECSP951529A (en) 1997-05-16

Family

ID=42042171

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP951529 ECSP951529A (en) 1995-09-05 1995-09-05 PHARMACEUTICAL COMPOUNDS

Country Status (1)

Country Link
EC (1) ECSP951529A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11130755B2 (en) 2016-11-07 2021-09-28 Sanofi Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11130755B2 (en) 2016-11-07 2021-09-28 Sanofi Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders
US11827633B2 (en) 2016-11-07 2023-11-28 Sanofi Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders

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