MX9301155A - NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION. - Google Patents

NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION.

Info

Publication number
MX9301155A
MX9301155A MX9301155A MX9301155A MX9301155A MX 9301155 A MX9301155 A MX 9301155A MX 9301155 A MX9301155 A MX 9301155A MX 9301155 A MX9301155 A MX 9301155A MX 9301155 A MX9301155 A MX 9301155A
Authority
MX
Mexico
Prior art keywords
sulfonamidocarboxamides
new
procedure
preparation
amidination
Prior art date
Application number
MX9301155A
Other languages
Spanish (es)
Inventor
Jean Ackermann
David Banner
Klaus Gubernator
Kurt Hilpert
Gerard Schmid
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX9301155A publication Critical patent/MX9301155A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Las nuevas sulfonamidocarboxamidas de la fórmula (I), en donde A, M, Q, X en Y tienen el significado expuesto en la descripción, así como sus hidratos o solvatos inhiben la agregación de plaquetas en la sangre inducida por trombina y coagulación de fibrinógeno en plasma. Se preparan mediante la amidinación de un grupo amino cíclico que corresponde a agrupación X o mediante formación a amida C(O)N(Q).The new sulfonamidocarboxamides of the formula (I), where A, M, Q, X in Y have the meaning set forth in the description, as well as their hydrates or solvates inhibit thrombin-induced blood platelet aggregation and fibrinogen coagulation in plasma. They are prepared by amidination of a cyclic amino group corresponding to group X or by formation of amide C (O) N (Q).

MX9301155A 1992-03-06 1993-03-02 NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION. MX9301155A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH72892 1992-03-06

Publications (1)

Publication Number Publication Date
MX9301155A true MX9301155A (en) 1993-09-01

Family

ID=4193803

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9301155A MX9301155A (en) 1992-03-06 1993-03-02 NEW SULFONAMIDOCARBOXAMIDES AND PROCEDURE FOR THEIR PREPARATION.

Country Status (10)

Country Link
KR (1) KR100274422B1 (en)
BR (1) BR9300753A (en)
HR (1) HRP930266A2 (en)
MX (1) MX9301155A (en)
PL (1) PL173030B1 (en)
SG (1) SG48063A1 (en)
SI (1) SI9300104A (en)
SK (1) SK14893A3 (en)
YU (1) YU14493A (en)
ZA (1) ZA931403B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201303B (en) * 1990-07-05 1993-03-01 Hoffmann La Roche

Also Published As

Publication number Publication date
SK14893A3 (en) 1993-11-10
PL297960A1 (en) 1993-09-20
YU14493A (en) 1997-01-08
ZA931403B (en) 1993-09-06
PL173030B1 (en) 1998-01-30
BR9300753A (en) 1993-09-08
SI9300104A (en) 1993-09-30
KR930019627A (en) 1993-10-18
KR100274422B1 (en) 2000-12-15
SG48063A1 (en) 1998-04-17
HRP930266A2 (en) 1996-04-30

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