WO2025189477A1 - 装载机构、生化物质分析装置和生化物质分析系统 - Google Patents

装载机构、生化物质分析装置和生化物质分析系统

Info

Publication number
WO2025189477A1
WO2025189477A1 PCT/CN2024/082038 CN2024082038W WO2025189477A1 WO 2025189477 A1 WO2025189477 A1 WO 2025189477A1 CN 2024082038 W CN2024082038 W CN 2024082038W WO 2025189477 A1 WO2025189477 A1 WO 2025189477A1
Authority
WO
WIPO (PCT)
Prior art keywords
component
loading mechanism
loading platform
support surface
guide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/CN2024/082038
Other languages
English (en)
French (fr)
Inventor
湛武
赵振涛
张宇宁
董宇亮
云全新
黎宇翔
章文蔚
徐讯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BGI Shenzhen Co Ltd
Original Assignee
BGI Shenzhen Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BGI Shenzhen Co Ltd filed Critical BGI Shenzhen Co Ltd
Priority to PCT/CN2024/082038 priority Critical patent/WO2025189477A1/zh
Publication of WO2025189477A1 publication Critical patent/WO2025189477A1/zh
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23P—METAL-WORKING NOT OTHERWISE PROVIDED FOR; COMBINED OPERATIONS; UNIVERSAL MACHINE TOOLS
    • B23P19/00—Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformation; Tools or devices therefor so far as not provided for in other classes
    • B23P19/04—Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformation; Tools or devices therefor so far as not provided for in other classes for assembling or disassembling parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25B—TOOLS OR BENCH DEVICES NOT OTHERWISE PROVIDED FOR, FOR FASTENING, CONNECTING, DISENGAGING, OR HOLDING
    • B25B11/00—Work holders not covered by any preceding group in the subclass, e.g. magnetic work holders, vacuum work holders
    • B25B11/02—Assembly jigs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25B—TOOLS OR BENCH DEVICES NOT OTHERWISE PROVIDED FOR, FOR FASTENING, CONNECTING, DISENGAGING, OR HOLDING
    • B25B27/00—Hand tools, specially adapted for fitting together or separating parts or objects whether or not involving some deformation, not otherwise provided for

Definitions

  • the present application relates to the field of analysis and testing, and in particular to a loading mechanism, a biochemical substance analysis device having the loading mechanism, and a biochemical substance analysis system having the biochemical substance analysis device.
  • a detection device is a component required for analytical instruments such as gene sequencers. It's the area where the sample reacts with the reagents, generating a corresponding signal.
  • the analytical instrument receives and analyzes this signal.
  • the detection device is temporarily mounted on the analytical instrument, establishing a conductive path for electrical signals between the two instruments.
  • the card holder of the analytical instrument needs to be manipulated to rotate to provide operating space for the subsequent insertion of the detection device.
  • the detection device is then inserted into the card holder by manual insertion, and then the card holder is pressed to return to its original position.
  • the metal contacts in the card holder are unevenly stressed and prone to wear, affecting the transmission of electrical signals.
  • the resistance encountered during insertion of the detection device increases, causing inconvenience to the user.
  • the terms “installed” and “connected” should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections, electrical connections, or mutual communication; they can refer to direct connections or indirect connections through an intermediate medium; they can refer to internal communication between two components or the interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on specific circumstances.
  • FIG 1 shows a biochemical substance analysis system 1000 provided in one embodiment of the present application, including a first component 1 and a biochemical substance analysis device 100.
  • Figure 2 shows the biochemical substance analysis device 100 obtained by removing the first component 1 from the biochemical substance analysis system 1000 shown in Figure 1.
  • the first component 1 can be used to accommodate fluids (such as biological samples and reagents) and detect the above-mentioned fluids to obtain corresponding signals.
  • the biochemical substance analysis device 100 is used to receive the above-mentioned signals from the first component 1 and analyze the signals to obtain the biological characteristics of the sample in the first component 1.
  • the biological characteristics can be the gene sequence of the sample, that is, the biochemical substance analysis device 100 can be a gene sequencer. It will be understood that the specific type of the biochemical substance analysis device 100 can also be changed according to its actual function.
  • the biochemical substance analysis device 100 includes a second component 2 for assembly with the first component 1.
  • the second component 2 can be a component inherent to the biochemical analysis device 100 itself, and is used to receive the above-mentioned signal from the first component 1 so that the biochemical substance analysis device 100 can analyze the signal.
  • the first component 1 can include a stacked microfluidic chip 1a, a detection chip 1b, and a carrier board 1c.
  • the microfluidic chip 1a is used for fluid to undergo biochemical reactions therein.
  • the detection chip 1b is used to detect the fluid that has reacted in the microfluidic chip 1a and generate corresponding signals.
  • the carrier board 1c is used to assemble with the second component 2 and send the above-mentioned signal to the second component 2.
  • the carrier board 1c can be a circuit board, and a plurality of first electrical connection parts C1 are provided on the plug-in end of the carrier board 1c.
  • the second component 2 includes a plug interface 2a, which is provided with a plurality of second electrical connection parts C2.
  • the first electrical connection part C1 contacts and electrically connects with the second electrical connection part C2, so that the signal at the first component 1 can be sent to the second component 2.
  • the second component 2 can also be connected to a main control board (not shown) through the second electrical connection part C2, so that the above-mentioned signal can be further received by the main control board.
  • the first electrical connection part C1 and the second electrical connection part C2 can be gold fingers or metal contacts. In other embodiments, it is also possible to provide the first component 1 with a plug interface and the second component 2 with a plug end.
  • the biochemical substance analysis device 100 may further include a heat transfer element 3, which is used to directly or indirectly contact the first component 1 to achieve heat conduction.
  • the heat transfer element 3 may be in direct contact with the first component 1, or it may be in indirect contact with the first component 1 through a thermally conductive adhesive. In this way, heat can be transferred between the first component 1 and the heat transfer element 3.
  • external heat can be conducted to the first component 1 through the heat transfer element 3, and the heat of the first component 1 itself can also be conducted to the outside through the heat transfer element 3, so that the temperature of the first component 1 is controlled within a preset range to ensure the reliability of the biochemical reaction in the first component 1.
  • the setting of the heat transfer element 3 can control the temperature of the first component 1 to fluctuate within the range of ⁇ 0.1°C of the preset temperature.
  • the heat transfer element 3 can be a heat transfer element. Heat transfer table made of metal with high conductivity.
  • the biochemical substance analysis device 100 further includes a loading mechanism 200 for assembling the first component 1 and the second component 2.
  • the loading mechanism 200 includes a base 10, a mounting seat 20, and a loading platform 30.
  • the mounting base 20 is fixed to the support surface 11.
  • the specific fixing method can be screwing, bonding or clamping, etc., which is not limited in this application.
  • the mounting base 20 has a first guide groove 21, and at least part of the first guide groove 21 is inclined relative to the first direction X.
  • the loading platform 30 is used to position the first component 1 and the second component 2.
  • the loading platform 30 includes a first positioning groove 31 and a second positioning groove 32 that communicate with each other.
  • the first positioning groove 31 matches the shape of the first component 1 and is used to position the first component 1 and restrict its movement in the second direction Y.
  • the second positioning groove 32 communicates with the first positioning groove 31 along a second direction Y perpendicular to the first direction X and is used to position the second component 2.
  • the second positioning groove 32 allows the second component 2 to move within the second direction Y.
  • the loading platform 30 is movably disposed on the support surface 11 along the first direction X.
  • the base 10 further includes a guide shaft 13 disposed on the support surface 11 and extending along the first direction X.
  • the loading platform 30 is provided with a guide hole 34, and the guide shaft 13 is movably inserted into the guide hole 34.
  • the cooperation between the guide hole 34 and the guide shaft 13 enables the loading platform 30 to move strictly along the first direction X, making the movement of the loading platform 30 more stable and smooth.
  • the number of the guide shafts 13 and the number of the guide holes 34 can be four, and the four guide holes 34 are respectively located at the four corners of the loading platform 30 .
  • the second component 2 is provided with a first guide member 2b that slides within a first guide groove 21.
  • the second component 2 can be assembled to the mounting base 20 via the first guide member 2b.
  • the first guide groove 21 is configured to cooperate with the first guide member 2b, so that when the loading platform 30 moves in the first direction X toward the support surface 11, the second component 2 moves in the second direction Y toward the first component 1 and assembles with the first component 1, bringing C1 and C2 into contact and achieving electrical connection.
  • the first guide groove 21 cooperates with the first guide member 2b to also ensure that when the loading platform 30 moves in the first direction X away from the support surface 11, the second component 2 moves in the second direction Y away from the first component 1 and disengages from the first component 1, separating C1 and C2 and severing the electrical connection.
  • the mounting base 20 may be provided with two first guide grooves 21.
  • two first guide members 2b are provided on opposite sides of the second component 2, each first guide member 2b slidingly disposed within a first guide groove 21, thereby ensuring smoother and more stable movement of the second component 2.
  • the first guide member 2b may be a columnar structure, but this application does not limit this.
  • the user only needs to place the first component 1 on the loading platform 30, and then control the loading platform 30 to move along the first direction X toward the support surface 11, so that the loading platform 30 drives the first component 1 and the second component 2 to move toward the support surface 11. Since at least part of the first guide groove 21 is tilted compared to the first direction X, during the movement of the loading platform 30, the cooperation between the first guide groove 21 and the first guide member 2b of the second component 2 causes the second component 2 to move along the second direction Y toward the first component 1 until the second component 2 is assembled with the first component 1. That is, this application avoids manual plug-in method.
  • the first component 1 is assembled to the second component 2 in a manner that reduces the risk of wear or even misalignment of C2 (e.g., metal contacts) within the second component 2, thereby improving the stability of electrical signal transmission. Furthermore, the manual insertion is replaced by manipulating the loading platform 30 to move along the first direction X, which improves user convenience.
  • C2 e.g., metal contacts
  • the user simply moves the loading platform 30 in the first direction X, away from the support surface 11. This causes the loading platform 30 to move the first and second components 1 and 2 away from the support surface 11.
  • the first guide groove 21 cooperates with the first guide member 2b to move the second component 2 in the second direction Y, away from the first component 1, until the second component 2 separates from the first component 1. This eliminates the need for manual extraction to separate the first component 1 from the second component 2, further enhancing user convenience.
  • the first guide slot 21 includes a first section 211 that is tilted relative to the first direction X.
  • the first section 211 includes a first end 2111 and a second end 2112 that are oppositely disposed.
  • the first end 2111 is located between the support surface 11 and the second end 2112 in the first direction X, i.e., the first end 2111 is positioned lower than the second end 2112.
  • the first end 2111 is closer to the first positioning slot 31 than the second end 2112 in the second direction Y.
  • the first guide groove 21 may also include a second section 212 connected to the first end 2111 and a third section 213 connected to the second end 2112. Specifically, the second section 212 is positioned lower than the third section 213. Both the second section 212 and the third section 213 extend along the first direction X.
  • the first section 211, the second section 212, and the third section 213 may all be linear grooves. In other embodiments, the second section 212 and the third section 213 may also be omitted, that is, the first guide groove 21 only includes the first section 211.
  • the first component 1 is assembled with the second component 2; when the first guide member 2b slides to the second end 2112 of the first section 211, the first component 1 is disengaged from the second component 2.
  • the mounting seat 20 is further provided with a second guide groove 22, and at least a portion of the second guide groove 22 is tilted compared to the first direction X.
  • the loading mechanism 200 also includes a limit member 40 movably provided on the loading platform 30.
  • the loading platform 30 may also be provided with a third positioning groove 33, and the third positioning groove 33 is connected to the first positioning groove 31 along a third direction Z that is perpendicular to both the first direction X and the second direction Y.
  • the third positioning groove 33 is used to place the limit member 40, and the third positioning groove 33 allows the limit member 40 to move therein along the third direction Z.
  • the limit member 40 is provided with a second guide member 40a that is slidably provided in the second guide groove 22.
  • the second guide groove 22 is used to cooperate with the second guide member 40a, so that when the loading platform 30 moves along the first direction X toward the support surface 11, the limit member 40 moves along the third direction Z toward the first positioning groove 31 until the limit member 40 moves To the top of the first positioning groove 31. At this time, when viewed from the first direction X, the limiter 40 overlaps with the first positioning groove 31. When the limiter 40 moves to the top of the first positioning groove 31, the limiter 40 can limit the movement of the first component 1 in the first direction X, thereby fixing the first component 1.
  • the loading mechanism 200 includes two limiters 40 arranged opposite to each other in the third direction Z, so as to provide a more uniform limiting force to the first component 1.
  • the mounting seat 20 can be provided with two second guide grooves 22 corresponding to each limiter 40, and correspondingly, two second guide members 40a are provided on opposite sides of each limiter 40, and each second guide member 40a is slidably provided in a second guide groove 22, so that the movement of the limiter 40 is more stable and smooth.
  • the second guide member 40a can be a columnar structure, but this application is not limited thereto.
  • the limiter 40 can be a block structure, but this application is not limited thereto.
  • the mounting base 20 may include a first mounting portion 20a and two second mounting portions 20b disposed opposite each other in a third direction Z.
  • the first mounting portion 20a is disposed between the two second mounting portions 20b.
  • a first guide groove 21 is disposed in the first mounting portion 20a, and a second guide groove 22 is disposed in the second mounting portion 20b.
  • the loading platform 30 is at least partially disposed within the space enclosed by the first mounting portion 20a and the second mounting portion 20b.
  • the second guide groove 22 can be similar to that of the first guide groove 21.
  • the second guide groove 22 includes a fourth section 221, which is arranged at an angle relative to the first direction X.
  • the fourth section 221 includes a third end 2211 and a fourth end 2212, which are arranged opposite each other.
  • the third end 2211 is located between the support surface 11 and the fourth end 2212 in the first direction X, that is, the third end 2211 is located lower than the fourth end 2212.
  • the third end 2211 is closer to the first positioning groove 31 than the fourth end 2212 in the third direction Z.
  • the limiting member 40 gradually approaches the first positioning groove 31 and the first component 1 located within the first positioning groove 31 until the limiting member 40 restricts the movement of the first component 1 in the first direction X.
  • the limiting member 40 gradually moves away from the first positioning groove 31 and the first component 1 located in the first positioning groove 31 until the limiting member 40 releases the first component 1 .
  • the second guide groove 22 may further include a fifth section 222 connected to the third end 2211 and a sixth section 223 connected to the fourth end 2212.
  • the fifth section 222 is positioned lower than the sixth section 223.
  • Both the fifth section 222 and the sixth section 223 extend along the first direction X.
  • the stopper 40 restricts movement of the first component 1 in the first direction X.
  • the stopper 40 releases the first component 1.
  • the fifth section 222 and the sixth section 223 may be omitted.
  • the limiting member 40 can be set to extend and move to the top of the first component 1 first, and then the second component 2 is extended, so that the position of the first component 1 is fixed when the first component 1 and the second component 2 are assembled, ensuring the smoothness and reliability of the assembly process.
  • the fourth section 221 of the second guide groove 22 can be set to be higher than the first section 211 of the first guide groove 21 (the cross-section in Figure 5 only cuts to the third end 2211 of the fourth section 221), that is, in the first direction X, the third end 2211 of the fourth section 221 is farther away from the support surface than the second end 2112 of the first section 211. 11.
  • the base 10 is provided with a first window 14 that passes through the support surface 11 and the bottom surface 12, and the loading platform 30 is provided with a second window 35 that passes through the bottom of the first positioning groove 31.
  • the first window 14 and the second window 35 overlap, and the first window 14 and the second window 35 are used to allow the heat transfer element 3 to pass through.
  • the heat transfer element 3 may include a first heat transfer portion 3a and a second heat transfer portion 3b that are connected. When viewed from the first direction X, the area of the first heat transfer portion 3a is larger than the area of the second heat transfer portion 3b. Please refer to Figure 5 as well.
  • the first heat transfer portion 3a is provided on one side of the bottom surface 12 of the base 10 and is set apart from the bottom surface 12.
  • the second heat transfer portion 3b extends from the first heat transfer portion 3a and passes through the first window 14 and the second window 35. Since the limiting member 40 can limit the movement of the first component 1 in the first direction X, it can ensure that the second heat transfer portion 3b of the heat transfer member 3 is in direct or indirect contact with the first component 1 to achieve heat conduction, and since the first heat transfer portion 3a is set at a distance from the bottom surface 12, it is also beneficial for the heat transfer member 3 to conduct heat away.
  • the detection chip is inserted into the card holder by manual plugging, and then the card holder is pressed to rotate it to the original position after the plugging is completed, and then the position of the detection chip is locked by a structure such as a lock.
  • the detection chip may bend under the pressure of the lock, causing the plug-in end of the detection chip to act on the metal contact in the card holder, thereby causing the metal contact to wear or even bend, and poor heat conduction occurs between the bent detection chip and the heat transfer member.
  • Some embodiments of the present application control the limiting member 40 to extend along the third direction Z instead of being pressed along the first direction X, so that the first component 1 will not have the problem of bending and deformation, thereby ensuring the reliability of the conduction of electrical signals and heat.
  • the loading mechanism 200 further includes an operating member 50, comprising a rotating portion 51 rotatably connected to the mounting base 20 via a first rotating shaft S1.
  • the rotating portion 51 is also connected to the loading platform 30.
  • a transmission portion 36 is provided on the outer side of the loading platform 30, and a first sliding groove 23 extending along the first direction X is provided on the second mounting portion 20b of the mounting base 20.
  • the transmission portion 36 movably passes through the first sliding groove 23 and is connected to the rotating portion 51.
  • the rotating portion 51 is configured to drive the loading platform 30 toward the support surface 11 along the first direction X when the rotating portion 51 rotates relative to the mounting base 20.
  • the operating member 50 may include two opposing rotating portions 51.
  • two transmission portions 36 may be provided on opposing outer sides of the loading platform 30, each transmission portion 36 being connected to one of the rotating portions 51. Therefore, when the two rotating portions 51 rotate relative to the mounting base 20, the two transmission portions 36 drive the loading platform 30 to move along the first direction X toward the support surface 11, allowing the loading platform 30 to move more smoothly.
  • the rotating portion 51 can be a bar-shaped structure, and the rotating portion 51 can also be provided with a second sliding groove 51a extending along the extension direction of the rotating portion 51.
  • the transmission portion 36 is slidably provided in the second sliding groove 51a, thereby realizing the connection between the transmission portion 36 and the rotating portion 51.
  • the transmission portion 36 can slide in the second sliding groove 51a, thereby avoiding the situation where the rotation of the rotating portion 51 is blocked when the transmission portion 36 is fixedly connected to the rotating portion 51.
  • the second sliding groove 51a can be a waist Type hole.
  • the operating member 50 may further include an operating portion 52 connected to the rotating portion 51.
  • the operating portion 52 includes two rotating portions 51, the operating portion 52 is connected between the two rotating portions 51.
  • the user can press the operating portion 52 to control the rotation of the rotating portion 51.
  • the operating portion 52 and the rotating portion 51 may be generally bar-shaped components, and the operating member 50 as a whole may be a U-shaped handle. In this case, the operating portion 52 acts like a lever, thereby achieving the purpose of saving effort.
  • the operating member 50 also includes a first elastic member 53, which is elastically connected to the mounting seat 20 and the rotating portion 51. During the process of rotating the operating member 50 to move the loading platform 30 along the first direction X toward the support surface 11, the first elastic member 53 is in a compressed state. When the operating member 50 is subsequently rotated in the opposite direction to move the loading platform 30 away from the support surface 11 along the first direction X, the elastic restoring force of the first elastic member 53 is used to maintain the operating portion 52 in the desired position (such as maintaining it at the highest point).
  • the number of the first elastic members 53 can be two, and the two first elastic members 53 are respectively located on both sides of the mounting seat 20 in the third direction Z.
  • the first elastic member 53 can be a torsion spring, which includes a first arm 531 and a second arm 532, the first arm 531 is connected to the mounting seat 20, that is, the first wall 531 is fixed in position, and the second arm 532 is connected to the rotating portion 51.
  • the loading mechanism 200 further includes a locking member 60 mounted on the base 10.
  • the locking member 60 is used to lock the operating portion 52, thereby maintaining the operating portion 50 in a desired position.
  • the locking member 60 may include a base 61 fixed to the base 10 and a locking portion 62 rotatably connected to the base 61 via a second rotation axis S2.
  • the locking portion 62 is used to lock the operating portion 52.
  • the locking portion 62 includes a body 621 rotatably connected to the base 61 and a tongue 622 protruding from the body 621.
  • the tongue 622 includes a locking surface 6220 perpendicular to the plane of the body 621.
  • the locking surface 6220 is used to lock the operating portion 52 when parallel to the support surface 11. More specifically, as shown in Figure 11 , the operating portion 52 is provided with a recess 52a.
  • the tongue 622 is adapted to fit within the recess 52a, with the locking surface 6220 abutting against the bottom surface 12 of the recess 52a.
  • the tongue portion 622 may further include an inclined surface 6221 disposed opposite the locking surface 6220.
  • the inclined surface 6221 is further away from the support surface 11 than the locking surface 6220.
  • the inclined surface 6221 is inclined relative to the support surface 11.
  • the locking member 60 also includes a second elastic member 63, which is configured to abut against the body 621. When the locking member 60 rotates away from the operating portion 52 under the action of the operating portion 52, the second elastic member 63 is in a compressed state.
  • the second elastic member 63 can be a torsion spring mounted on the second rotating shaft S2, which includes a third arm 631 and a fourth arm 632.
  • the third arm 631 is elastically supported on the main body 621, and the position of the fourth arm 632 is fixed (for example, the fourth arm 632 can be elastically supported on the horizontal plane supporting the loading mechanism 200).
  • the base 10 further includes a third elastic member 15 wound around each guide shaft 13, and the third elastic member 15 elastically abuts against the support surface 11 and the loading platform 30.
  • the third elastic member 15 is used to eliminate the loading platform 30 from moving along the first direction X to the point where the first component 1 directly or indirectly contacts the heat transfer element 3.
  • the third elastic member 15 can be a helical cylindrical spring.
  • the working principle of the loading mechanism 200 of the present application is as follows: Referring to Figures 13 and 14, the user manually places the first component 1 in the first positioning groove 31 of the loading platform 30, and then presses the operating portion 52 of the operating member 50 to rotate the operating member 50 toward the base 10. At this time, the operating member 50 transmits downward pressure to the loading platform 30 through the transmission portion 36 provided on the outer side of the loading platform 30, causing the loading platform 30 to move toward the support surface 11 along the first direction X. During the process of the loading platform 30 moving toward the support surface 11 along the first direction X, the limiting member 40 slides within the second guide groove 22 via the second guide member 40a (shown in Figures 6 and 7).
  • the cooperation between the second guide groove 22 and the second guide member 40a causes the limiting member 40 to move along the third direction Z toward the first positioning groove 31 until the limiting member 40 moves above the first positioning groove 31 and restricts the movement of the first component 1 in the first direction X.
  • the second component 2 slides within the first guide groove 21 via the first guide member 2b (shown in Figures 3 and 5).
  • the cooperation between the first guide groove 21 and the first guide member 2b causes the second component 2 to move toward the first component 1 along the second direction Y and assemble with the first component 1.
  • the first component 1 When the operating portion 52 is pressed to its lowest point, the first component 1 directly or indirectly contacts the heat transfer member 3, achieving heat transfer. At this point, the locking member 60 is reset under the action of the second elastic member 63, locking the operating portion 52 and maintaining the operating member 50 in the desired position.
  • the locking member 60 can be rotated away from the operating portion 52 to release the operating portion 52.
  • the operating portion 52 can be rotated to rotate the operating member 50 away from the base 10.
  • the operating member 50 then transmits an upward thrust to the loading platform 30 via the transmission portion 36 disposed outside the loading platform 30, causing the loading platform 30 to move in the first direction X away from the support surface 11.
  • the second component 2 slides within the first guide groove 21 via the first guide member 2b.
  • the interaction between the first guide groove 21 and the first guide member 2b causes the second component 2 to move in the second direction Y away from the first component 1 and disengage from the first component 1.
  • the limiting member 40 slides within the second guide groove 22 via the second guide member 40a.
  • the interaction between the second guide groove 22 and the second guide member 40a causes the limiting member 40 to move in the third direction Z away from the first positioning groove 31 until the limiting member 40 releases its restraint on the first component 1. Then, the first component 1 located in the first positioning groove 31 can be taken out.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

一种装载机构（200）、生化物质分析装置（100）和生化物质分析系统（1000）。装载机构（200）包括基座（10）、安装座（20）以及装载台（30）。基座（10）包括支撑面（11），定义第一方向（X）垂直于支撑面（11）。安装座（20）固定于支撑面（11）上，安装座（20）设有第一导向槽（21），至少部分第一导向槽（21）相较于第一方向（X）倾斜设置。装载台（30）被配置为放置第一部件（1）和第二部件（2），且沿第一方向（X）可活动地设于支撑面（11）上。第二部件（2）上设有滑动地设于第一导向槽（21）中的第一导引件（2b）。第一导向槽（21）被配置为与第一导引件（2b）配合，使得装载台（30）沿第一方向（X）朝向支撑面（11）运动时，第二部件（2）沿与第一方向（X）垂直的第二方向（Y）朝向第一部件（1）运动并与第一部件（1）装配。

Description

装载机构、生化物质分析装置和生化物质分析系统 技术领域
本申请涉及分析测试领域，尤其涉及一种装载机构，具有该装载机构的生化物质分析装置、以及具有该生化物质分析装置的生化物质分析系统。
背景技术
检测装置是诸如基因测序仪等分析仪器上所需的部件。检测装置是被测样品与试剂发生反应并产生相应信号的区域，分析仪器用于接收并分析上述信号。在使用时，检测装置临时装载在该类分析仪器上，使得检测装置和分析仪器之间建立电信号的传导路径。
相关技术中，需要操控分析仪器的卡座转动以便于为后续检测装置的插接提供操作空间，然后通过手动插接的方式将检测装置插入卡座内，再按压卡座使其返回原始位置。然而，若插入的时候有歪斜，卡座内的金属触点受力不均匀容易发生磨损，影响电信号的传导。而且，若金属触点数量较多，则检测装置插入时受到的阻力增加，导致用户操作不便。
发明内容
为解决以上缺陷的至少之一，有必要提出一种装载机构、生化物质分析装置和生化物质分析系统。
本申请第一方面提供一种装载机构，被配置为将第一部件与第二部件装配。所述装载机构包括基座、安装座以及装载台。所述基座包括支撑面，定义第一方向垂直于所述支撑面。所述安装座固定于所述支撑面上，所述安装座设有第一导向槽，至少部分所述第一导向槽相较于所述第一方向倾斜设置。所述装载台被配置为放置所述第一部件和所述第二部件，且沿所述第一方向可活动地设于所述支撑面上。所述第二部件上设有滑动地设于所述第一导向槽中的第一导引件。所述第一导向槽被配置为与所述第一导引件配合，使得所述装载台沿所述第一方向朝向所述支撑面运动时，所述第二部件沿与所述第一方向垂直的第二方向朝向所述第一部件运动并与所述第一部件装配。
本申请第二方面提供一种生化物质分析装置，包括第二部件。所述生化物质分析装置还包括如上所述的装载机构，所述第二部件设于所述装载机构的装载台中。
本申请第三方面提供一种生化物质分析系统，包括第一部件。所述生化物质分 析系统还包括如上所述的生化物质分析装置，所述第一部件被配置为放置于所述生化物质分析装置的装载机构的装载台中并与所述第二部件装配。
本申请中，用户只需要将第一部件放置于装载台上，然后操控装载台沿第一方向朝向支撑面运动。由于至少部分第一导向槽相较于第一方向倾斜设置，在装载台的运动过程中，第一导向槽与第一导引件的配合使得第二部件沿第二方向朝向第一部件运动，直至第二部件与第一部件装配。即，本申请避免通过手动插接的方式将第一部件装配至第二部件，从而降低两者未对齐的情况下第二部件发生磨损甚至歪斜的风险，提高电信号的传导的稳定性。而且，将手动插接改为操控装载台沿第一方向运动，可提高用户操作的便捷性。
附图说明
图1为本申请一实施方式提供的生化物质分析系统的分解图。
图2为图1所示的生化物质分析系统中的生化物质分析装置的结构示意图。
图3为图1所示的生化物质分析系统中的第一部件和第二部件的结构示意图。
图4为图3所示的第一部件的分解图。
图5为图2所示的生化物质分析装置沿V-V的剖视图。
图6为图2所示的生化物质分析装置中的基座、安装座和装配台的结构示意图。
图7为图6所示的装配台的分解图。
图8为图6所示的安装座的第一安装部的结构示意图。
图9为图6所示的安装座的第二安装部的结构示意图。
图10为图6所示的安装座的另一第二安装部的结构示意图。
图11为图2所示的生化物质分析装置中的操作件的结构示意图。
图12为图2所示的生化物质分析装置中的锁扣件的结构示意图。
图13为图1所示的生化物质分析系统处于一种状态时的结构示意图。
图14为图1所示的生化物质分析系统处于另一种状态时的结构示意图。
主要元件符号说明
第一部件                      1
微流控芯片                    1a
检测芯片                      1b
载板                         1c
第二部件                      2
插接口                       2a
第一导引件                    2b
传热件                       3
第一传热部                    3a
第二传热部                   3b
基座                         10
支撑面                       11
底面                         12
导向轴                       13
第一开窗                      14
第三弹性件                    15
安装座                       20
第一安装部                    20a
第二安装部                    20b
第一导向槽                   21
第二导向槽                    22
第一滑动槽                   23
装载台                       30
第一定位槽                    31
第二定位槽                   32
第三定位槽                   33
导向孔                       34
第二开窗                     35
传动部                       36
限位件                       40
第二导引件                    40a
操作件                       50
转动部                       51
第二滑动槽                    51a
操作部                       52
凹部                         52a
第一弹性件                    53
锁扣件                       60
座体                         61
锁扣部                       62
第二弹性件                    63
生化物质分析装置              100
装载机构                     200
第一段                       211
第二段                       212
第三段                       213
第四段                       221
第五段                       222
第六段                         223
第一臂                         531
第二臂                         532
本体                           621
舌部                           622
第三臂                         631
第四臂                         632
生化物质分析系统               1000
第一端部                       2111
第二端部                       2112
第三端部                       2211
第四端部                       2212
锁定面                         6220
倾斜面                         6221
第一电连接部                  C1
第一电连接部                  C2
第一方向                      X
第二方向                      Y
第三方向                      Z
第一转轴                      S1
第二转轴                      S2
如下具体实施方式将结合上述附图进一步说明本申请。
具体实施方式
为了能够更清楚地理解本申请的上述目的、特征和优点，下面结合附图和具体实施例对本申请进行详细描述。需要说明的是，在不冲突的情况下，本申请的实施例及实施例中的特征可以相互组合。在下面的描述中阐述了很多具体细节以便于充分理解本申请，所描述的实施例仅是本申请一部分实施例，而不是全部的实施例。
在本申请的描述中，需要理解的是，术语“上”、“下”、“前”、“后”、“顶”、“底”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本申请和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本申请的限制。此外，术语“第一”、“第二”仅用于描述目的，而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此，限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个所述特征。在本申请的描述中，需要说明的是，“多个”的含义是两个或两个以上，除非另有明确具体的限定。
在本申请的描述中，需要说明的是，除非另有明确的规定和限定，术语“安装”、“连接”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接或可以相互通讯，可以是直接相连，也可以通过中间媒介间接相连，可以是两个元件内部的连通或两个元件的相互作用关系。对于本领域的普通技术人员而言，可以根据具体情况理解上述术语在本申请中的具体含义。
图1示出本申请一实施方式提供的生化物质分析系统1000，包括第一部件1和生化物质分析装置100。图2示出图1所示的生化物质分析系统1000去掉第一部件1后得到的生化物质分析装置100。其中，第一部件1可用于容纳流体(如生物样本和试剂)，并对上述流体进行检测以获得相应的信号。生化物质分析装置100用于从第一部件1处接收上述信号并对该信号进行分析，从而得到第一部件1内的样品的生物特征。例如，生物特征可以是样品的基因序列，即生化物质分析装置100可以是基因测序仪。可以理解，生化物质分析装置100的具体类型还可以根据其实际功能变更。
如图2所示，生化物质分析装置100包括用于与第一部件1装配的第二部件2。第二部件2可以是生化分析装置100本身固有的部件，用于从第一部件1处接收上述信号，以供生化物质分析装置100对该信号进行分析。请参阅图3和图4，在一些实施例中，第一部件1可以包括层叠设置的微流控芯片1a、检测芯片1b以及载板1c。微流控芯片1a用于供流体在其内发生生化反应。检测芯片1b用于检测微流控芯片1a内已发生反应的流体并产生相应的信号。载板1c用于与第二部件2装配并将上述信号发送至第二部件2。其中，载板1c可以是电路板，载板1c的插接端上设有多个第一电连接部C1。
第二部件2包括插接口2a，插接口2a内设有多个第二电连接部C2。当载板1c的插接端插入插接口2a时，第一电连接部C1与第二电连接部C2接触并电连接，使得第一部件1处的信号可发送至第二部件2。第二部件2还可通过第二电连接部C2连接一主控板(图未示)，使得上述信号可进一步被主控板接收。其中，第一电连接部C1和第二电连接部C2可以是金手指或金属触点。在其它实施例中，也可以设置第一部件1具有插接口且第二部件2具有插接端。
如图2所示，在一些实施例中，生化物质分析装置100还可包括传热件3，传热件3用于与第一部件1直接或间接接触以实现热传导。如，传热件3可以与第一部件1直接接触，也可以通过导热胶与第一部件1间接接触。如此，热量可在第一部件1和传热件3之间传递，例如，外部热量可经传热件3传导至第一部件1，第一部件1本身的热量也可以经传热件3传导至外部，使得第一部件1的温度控制在预设范围内以保证第一部件1内生化反应的可靠性。例如，传热件3的设置可控制第一部件1的温度在预设温度±0.1℃的范围内波动。其中，传热件3可以是采用热 导系数较高的金属制成的传热台。
生化物质分析装置100还包括装载机构200，装载机构200用于将第一部件1与第二部件2装配。装载机构200包括基座10、安装座20以及装载台30。
请结合参阅图2、图5和图6，基座10可以为板状物体，其包括在第一方向X上相对设置的支撑面11和底面12。支撑面11和底面12均垂直于第一方向X。
安装座20固定于支撑面11上，具体的固定方式可以是螺接、粘接或者卡接等，本申请不作限制。安装座20设有第一导向槽21，至少部分第一导向槽21相较于第一方向X倾斜设置。
请参阅图5至图7，装载台30用于放置第一部件1和第二部件2。在一些实施例中，装载台30包括相连通的第一定位槽31和第二定位槽32。第一定位槽31与第一部件1的形状适配，用于放置第一部件1且限制第一部件1沿第二方向Y的运动。第二定位槽32沿与第一方向X垂直的第二方向Y连通第一定位槽31，且用于放置第二部件2，第二定位槽32允许第二部件2沿第二方向Y在其内运动。装载台30沿第一方向X可活动地设于支撑面11上。在一些实施例中，基座10还包括设于支撑面11上的导向轴13，导向轴13沿第一方向X延伸。装载台30设有导向孔34，导向轴13可活动地穿设于导向孔34。导向孔34和导向轴13的配合使得装载台30能够严格沿着第一方向X运动，且使得装载台30的运动更加平稳和顺畅。其中，为达到更好的导引效果，可设置导向轴13和导向孔34的数量均为四个，其四个导向孔34分别位于装载台30的四个边角处。
第二部件2上设有滑动地设于第一导向槽21中的第一导引件2b。第二部件2可通过第一导引件2b装配于安装座20。第一导向槽21用于与第一导引件2b配合，使得装载台30沿第一方向X朝向支撑面11运动时，第二部件2沿第二方向Y朝向第一部件1运动并与第一部件1装配，使得C1和C2接触并实现电连接。第一导向槽21与第一导引件2b配合，还可使得装载台30沿第一方向X背离支撑面11运动时，第二部件2沿第二方向Y背离第一部件1运动并与第一部件1脱离，使得C1和C2分离以断开电连接。在一些具体的实施例中，安装座20上可设有两个第一导向槽21，对应地，第二部件2的相对两侧设有两个第一导引件2b，每一第一导引件2b滑动地设于一个第一导向槽21中，从而使得第二部件2的运动更加平稳和顺畅。其中，第一导引件2b可以为柱体结构，但本申请不作限制。
本申请中，若需要将第一部件1与第二部件2装配，用户只需要将第一部件1放置于装载台30上，然后操控装载台30沿第一方向X朝向支撑面11运动，从而使得装载台30带动第一部件1和第二部件2朝向支撑面11运动。由于至少部分第一导向槽21相较于第一方向X倾斜设置，在装载台30的运动过程中，第一导向槽21与第二部件2的第一导引件2b的配合使得第二部件2沿第二方向Y朝向第一部件1运动，直至第二部件2与第一部件1装配。即，本申请避免通过手动插接的方 式将第一部件1装配至第二部件2，从而降低两者未对齐的情况下第二部件2内的C2(如金属触点)发生磨损甚至歪斜的风险，提高电信号的传导的稳定性。而且，将手动插接改为操控装载台30沿第一方向X运动，可提高用户操作的便捷性。
同理，若需要使第一部件1与第二部件2脱离，用户只需要操控装载台30沿第一方向X背离支撑面11运动，从而使得装载台30带动第一部件1和第二部件2背离支撑面11运动。在装载台30的运动过程中，第一导向槽21与第一导引件2b的配合使得第二部件2沿第二方向Y背离第一部件1运动，直至第二部件2与第一部件1分离。即，本申请避免通过手动拔出的方式使第一部件1脱离第二部件2，进一步提高用户操作的便捷性。
请参阅图5、图6和图8，在一些实施例中，第一导向槽21包括相较于第一方向X倾斜设置的第一段211。第一段211包括相对设置的第一端部2111和第二端部2112，第一端部2111在第一方向X上位于支撑面11和第二端部2112之间，即第一端部2111相较于第二端部2112的位置更低。第一端部2111在第二方向Y上相较于第二端部2112更靠近第一定位槽31。当第一导引件2b从第二端部2112向第一端部2111滑动时，第二部件2逐渐靠近第一定位槽31以及位于第一定位槽31内的第一部件1，直至第一部件1与第二部件2装配。相反，当第一导引件2b从第一端部2111向第二端部2112滑动时，第二部件2逐渐远离第一定位槽31以及位于第一定位槽31内的第一部件1，直至第一部件1与第二部件2脱离。
进一步地，第一导向槽21还可包括连接于第一端部2111的第二段212以及连接于第二端部2112的第三段213，即第二段212相较于第三段213的位置更低。第二段212和第三段213均沿着第一方向X延伸。当第一导引件2b滑动至第二段212时，第一部件1与第二部件2装配；当第一导引件2b滑动至第三段213时，第一部件1与第二部件2脱离。其中，第一段211、第二段212和第三段213可均为线形槽。在其它实施例中，第二段212和第三段213也可以省略，即第一导向槽21仅包括第一段211，此时，当第一导引件2b滑动至第一段211的第一端部2111时，第一部件1与第二部件2装配；当第一导引件2b滑动至第一段211的第二端部2112时，第一部件1与第二部件2脱离。
如图6和图7所示，在一些实施例中，安装座20还设有第二导向槽22，至少部分第二导向槽22相较于第一方向X倾斜设置。装载机构200还包括可活动地设于装载台30上的限位件40。其中，装载台30还可设有第三定位槽33，第三定位槽33沿与第一方向X和第二方向Y均垂直的第三方向Z上连通第一定位槽31，第三定位槽33用于放置限位件40，且第三定位槽33允许限位件40沿第三方向Z在其内运动。限位件40上设有滑动地设于第二导向槽22的第二导引件40a。第二导向槽22用于与第二导引件40a配合，使得装载台30沿第一方向X朝向支撑面11运动时，限位件40沿第三方向Z朝向第一定位槽31运动，直至限位件40运动 至第一定位槽31上方。此时从第一方向X观察时，限位件40与第一定位槽31存在重叠。当限位件40运动至第一定位槽31上方时，限位件40可在第一方向X上限制第一部件1的运动，从而实现对第一部件1的固定。在一些具体的实施例中，装载机构200包括两个在第三方向Z上相对设置的限位件40，从而可向第一部件1提供更加均匀的限制力。进一步地，安装座20可对应于每一限位件40设有两个第二导向槽22，对应地，每一限位件40的相对两侧设有两个第二导引件40a，每一第二导引件40a滑动地设于一个第二导向槽22中，从而使得限位件40的运动更加平稳和顺畅。其中，第二导引件40a可以为柱体结构，但本申请不作限制。其中，限位件40可以为块体结构，但本申请不作限制。
结合参照图6、图8至图10，其中，安装座20可包括第一安装部20a和两个在第三方向Z上相对设置的第二安装部20b，第一安装部20a设于两个第二安装部20b之间。第一导向槽21设于第一安装部20a，第二导向槽22设于第二安装部20b。装载台30至少部分设于第一安装部20a和第二安装部20b围设形成的空间内。
如图9和图10所示，第二导向槽22的具体结构可以与第一导向槽21的具体结构相似。第二导向槽22包括相较于第一方向X倾斜设置的第四段221。第四段221包括相对设置的第三端部2211和第四端部2212，第三端部2211在第一方向X上位于支撑面11和第四端部2212之间，即第三端部2211相较于第四端部2212的位置更低。第三端部2211在第三方向Z上相较于第四端部2212更靠近第一定位槽31。当第二导引件40a从第四端部2212向第三端部2211滑动时，限位件40逐渐靠近第一定位槽31以及位于第一定位槽31内的第一部件1，直至限位件40在第一方向X上限制第一部件1的运动。相反，当第二导引件40a从第三端部2211向第四端部2212滑动时，限位件40逐渐远离第一定位槽31以及位于第一定位槽31内的第一部件1，直至限位件40松开第一部件1。
进一步地，第二导向槽22还可包括连接于第三端部2211的第五段222以及连接于第四端部2212的第六段223，即第五段222相较于第六段223的位置更低。第五段222和第六段223均沿着第一方向X延伸。当第二导引件40a滑动至第五段222时，限位件40在第一方向X上限制第一部件1的运动；当第二导引件40a滑动至第六段223时，限位件40松开第一部件1。在其它实施例中，第五段222和第六段223也可以省略。
其中，一方面，可设置限位件40先伸出并运动至第一部件1上方，然后第二部件2再伸出，使得第一部件1与第二部件2装配时第一部件1的位置固定，保证装配过程的顺畅和可靠性。为实现限位件40运动至第一部件1上方后第二部件2再伸出，如图5所示，可设置第二导向槽22的第四段221高于第一导向槽21的第一段211(图5中剖切面仅剖到第四段221的第三端部2211)，即在第一方向X上，第四段221的第三端部2211相较于第一段211的第二端部2112更远离支撑面 11。
另一方面，如图6和图7所示，基座10设有贯穿支撑面11和底面12的第一开窗14，装载台30设有贯穿第一定位槽31的槽底的第二开窗35。从第一方向X观察，第一开窗14和第二开窗35存在重叠，第一开窗14和第二开窗35用于供传热件3穿过。具体地，传热件3可包括相连接的第一传热部3a和第二传热部3b，从第一方向X观察，第一传热部3a的面积大于第二传热部3b的面积。请一并参照图5，第一传热部3a设于基座10的底面12一侧且与底面12相距设置，第二传热部3b自第一传热部3a延伸并穿过第一开窗14和第二开窗35。由于限位件40可在第一方向X上限制第一部件1的运动，因此可保证传热件3的第二传热部3b与第一部件1直接或间接接触以实现热量传导，且由于第一传热部3a与底面12相距设置，也利于传热件3将热量传导出去。相关技术中，通过手动插接的方式将检测芯片插入卡座内，然后在插接完成后按压卡座使其转动至原始位置，再通过诸如锁扣之类的结构锁定检测芯片的位置，然而检测芯片可能会在锁扣的压力下弯曲，导致检测芯片的插接端作用于卡座内的金属触点，进而导致金属触点发生磨损甚至歪斜，而且弯曲的检测芯片与传热件之间出现热传导不良。本申请一些实施例通过控制限位件40沿第三方向Z伸出而非沿第一方向X压紧，因此第一部件1不会出现弯曲变形问题，从而可保证电信号和热量的传导可靠性。
结合参照图2、图6和图11，在一些实施例中，装载机构200还包括操作件50，操作件50包括通过第一转轴S1转动连接于安装座20的转动部51。转动部51还连接于装载台30。例如，装载台30的外侧设有传动部36，安装座20的第二安装部20b设有沿第一方向X延伸的第一滑动槽23，传动部36可活动地穿过第一滑动槽23并连接于转动部51。转动部51用于在相较于安装座20转动时，带动装载台30沿着第一方向X朝向支撑面11运动，在装载台30沿着第一方向X朝向支撑面11运动的过程中，传动部36沿着第一滑动槽23滑动。因此，用户可转动该转动部51相较于安装座20转动，从而操控装载台30沿第一方向X朝向支撑面11运动。更具体地，为了对装载台30施加更加均匀的传动力，操作件50可包括两个相对设置的转动部51，对应地，装载台30相对的外侧可设有两个传动部36，每一传动部36连接于一个转动部51。因此，当两个转动部51相较于安装座20转动时，两个传动部36带动装载台30沿着第一方向X朝向支撑面11运动，使得装载台30运动更加顺畅。
进一步地，转动部51可以为条形结构，转动部51还可设有沿着转动部51的延伸方向延伸的第二滑动槽51a。传动部36滑动地设于第二滑动槽51a内，从而实现传动部36与转动部51的连接。在装载台30沿着第一方向X朝向支撑面11运动的过程中，传动部36可在第二滑动槽51a内滑动，从而避免了传动部36与转动部51固定连接时导致转动部51转动受阻的情况。其中，第二滑动槽51a可以为腰 型孔。
操作件50还可包括连接于转动部51的操作部52。当操作部52包括两个转动部51时，操作部52连接于两个转动部51之间。用户可按压操作部52，通过操作部52控制转动部51转动。其中，操作部52和转动部51可大致为条形部件，操作件50整体为U型的手柄，此时操作部52类似一省力杠杆，可实现省力的目的。
在一些实施例中，操作件50还包括第一弹性件53，第一弹性件53弹性连接于安装座20和转动部51。在转动操作件50使装载台30沿着第一方向X朝向支撑面11运动的过程中，第一弹性件53处于压紧状态。当后续反向转动操作件50使装载台30沿着第一方向X背离支撑面11运动时，第一弹性件53的弹性回复力用于使操作部52维持在所需位置(如维持在最高点)。在一些实施例中，第一弹性件53的数量可以为两个，两个第一弹性件53分别位于安装座20在第三方向Z上的两侧。其中，第一弹性件53可以为扭簧，其包括第一臂531和第二臂532，第一臂531连接于安装座20即第一壁531位置固定，第二臂532连接于转动部51。
结合参照图6和图12，在一些实施例中，装载机构200还包括安装于基座10的锁扣件60，锁扣件60用于锁定操作部52，从而使操作件50维持在所需位置。锁扣件60可包括固定于基座10的座体61和通过第二转轴S2转动连接于座体61的锁扣部62，锁扣部62用于锁定操作部52。更进一步地，锁扣部62包括转动连接于座体61的本体621和凸设于本体621的舌部622。舌部622包括垂直于本体621所在平面的锁定面6220，锁定面6220用于平行于支撑面11时锁定操作部52。更具体地，如图11所示，操作部52上设有凹部52a，舌部622可嵌入凹部52a内，且锁定面6220抵持于凹部52a的底面12。
在一些实施例中，舌部622还可包括与锁定面6220相对设置的倾斜面6221，在第一方向X上，倾斜面6221相较于锁定面6220更远离支撑面11。倾斜面6221相较于支撑面11倾斜设置。当操作件50朝向基座10转动时，操作部52可作用于倾斜面6221，使得锁扣件60沿背离操作部52的方向转动，从而使操作部52被按压至最低点时。锁扣件60还包括第二弹性件63，第二弹性件63用于抵持于本体621。当锁扣件60在操作部52的作用下沿背离操作部52的方向转动时，第二弹性件63处于压紧状态，其弹性回复力用于使锁扣件60复位(即，使锁扣件60沿朝向操作部52的方向转动)，进而使锁定面6220平行于支撑面11以锁定操作部52。其中，第二弹性件63可以为套设于第二转轴S2的扭簧，其包括第三臂631和第四臂632，第三臂631弹性抵持于本体621，第四臂632的位置固定(如，第四臂632可弹性抵持于支撑装载机构200的水平面上)。
如图2和图5所示，在一些实施例中，基座10还包括绕设于每一导向轴13的第三弹性件15，第三弹性件15弹性抵持于支撑面11和装载台30。第三弹性件15用于消除装载台30在沿第一方向X运动至第一部件1直接或间接接触传热件3时 出现的窜动间隙。其中，第三弹性件15可以为螺旋圆柱弹簧
综上所述，本申请的装载机构200的工作原理为：请参阅图13和图14，用户手动将第一部件1放置于装载台30的第一定位槽31，然后按压操作件50的操作部52使操作件50朝向基座10转动，此时操作件50通过装载台30外侧设置的传动部36向装载台30传递向下的压力，使得装载台30沿第一方向X朝向支撑面11运动。在装载台30沿第一方向X朝向支撑面11运动的过程中，限位件40通过第二导引件40a(在图6和图7中示出)在第二导向槽22内滑动，第二导向槽22与第二导引件40a的配合使得限位件40沿第三方向Z朝向第一定位槽31运动，直至限位件40运动至第一定位槽31上方并在第一方向X上限制第一部件1的运动。接着，第二部件2通过第一导引件2b(在图3和图5中示出)在第一导向槽21内滑动，第一导向槽21和第一导引件2b的配合使得第二部件2沿第二方向Y朝向第一部件1运动并与第一部件1装配。当操作部52被按压至与锁扣件60的倾斜面6221接触时，锁扣件60沿背离操作部52的方向转动，从而使操作部52被按压至最低点时，第一部件1与传热件3直接或间接接触并实现热量传导。此时锁扣件60在第二弹性件63的作用下复位，使锁扣件60锁定操作部52并使操作件50维持在所需位置。
当完成检测后，可沿背离操作部52的方向转动锁扣件60，使锁扣件60松开操作部52。此时，可转动操作部52使操作件50背离基座10转动，此时操作件50通过装载台30外侧设置的传动部36向装载台30传递向上的推力，使得装载台30沿第一方向X背离支撑面11运动。在装载台30沿第一方向X背离支撑面11运动的过程中，第二部件2通过第一导引件2b在第一导向槽21内滑动，第一导向槽21和第一导引件2b的配合使得第二部件2沿第二方向Y背离第一部件1运动并与第一部件1脱离。接着，限位件40通过第二导引件40a在第二导向槽22内滑动，第二导向槽22与第二导引件40a的配合使得限位件40沿第三方向Z背离第一定位槽31运动，直至限位件40解除对第一部件1的限制。然后，可将位于第一定位槽31内的第一部件1取出。
最后应说明的是，以上实施例仅用以说明本申请的技术方案而非限制，尽管参照较佳实施例对本申请进行了详细说明，本领域的普通技术人员应当理解，可以对本申请的技术方案进行修改或等同替换，而不脱离本申请技术方案的精神和范围。

Claims (28)

  1. 一种装载机构，被配置为将第一部件与第二部件装配，其特征在于，所述装载机构包括：
    基座，包括支撑面，定义第一方向垂直于所述支撑面；
    安装座，固定于所述支撑面上，所述安装座设有第一导向槽，至少部分所述第一导向槽相较于所述第一方向倾斜设置；以及
    装载台，被配置为放置所述第一部件和所述第二部件，且沿所述第一方向可活动地设于所述支撑面上，所述第二部件上设有滑动地设于所述第一导向槽中的第一导引件，所述第一导向槽被配置为与所述第一导引件配合，使得所述装载台沿所述第一方向朝向所述支撑面运动时，所述第二部件沿与所述第一方向垂直的第二方向朝向所述第一部件运动并与所述第一部件装配。
  2. 如权利要求1所述的装载机构，其特征在于，所述第一导向槽还被配置为与所述第一导引件配合，使得所述装载台沿所述第一方向背离所述支撑面运动时，所述第二部件沿所述第二方向背离所述第一部件运动并与所述第一部件脱离。
  3. 如权利要求1所述的装载机构，其特征在于，所述装载台包括相连通的第一定位槽和第二定位槽，所述第一定位槽被配置为放置所述第一部件，所述第二定位槽被配置为放置所述第二部件，所述第二定位槽被配置为允许所述第二部件沿所述第二方向运动。
  4. 如权利要求3所述的装载机构，其特征在于，所述第一导向槽包括相较于所述第一方向倾斜设置的第一段，所述第一段包括相对设置的第一端部和第二端部，所述第一端部在所述第一方向上位于所述支撑面和所述第二端部之间，所述第一端部在所述第二方向上相较于所述第二端部更靠近所述第一定位槽。
  5. 如权利要求4所述的装载机构，其特征在于，所述第一导向槽还包括连接于所述第一端部的第二段以及连接于所述第二端部的第三段，所述第二段和所述第三段均沿着所述第一方向延伸。
  6. 如权利要求4所述的装载机构，其特征在于，所述安装座还设有第二导向槽，至少部分所述第二导向槽相较于所述第一方向倾斜设置，所述装载机构还包括设于所述装载台的限位件，所述限位件上设有滑动地设于所述第二导向槽的第二导引件，所述第二导向槽被配置为与所述第二导引件配合，使得所述装载台沿所述第一方向朝向所述支撑面运动时，所述限位件沿与所述第一方向和所述第二方向均垂直 的第三方向朝向所述第一定位槽运动。
  7. 如权利要求6所述的装载机构，其特征在于，所述第二导向槽包括相较于所述第一方向倾斜设置的第四段，所述第四段包括相对设置的第三端部和第四端部，所述第三端部在所述第一方向上位于所述支撑面和所述第四端部之间，所述第三端部在所述第三方向上相较于所述第四端部更靠近所述第一定位槽。
  8. 如权利要求7所述的装载机构，其特征在于，在所述第一方向上，所述第三端部相较于所述第二端部更远离所述支撑面。
  9. 如权利要求6所述的装载机构，其特征在于，所述装载台还包括与所述第一定位槽连通的第三定位槽，所述第三定位槽被配置为放置所述限位件，所述第三定位槽被配置为允许所述限位件沿所述第三方向运动。
  10. 如权利要求3所述的装载机构，其特征在于，所述基座设有贯穿所述支撑面的第一开窗，所述装载台设有贯穿所述第一定位槽的第二开窗，从所述第一方向观察，所述第一开窗和所述第二开窗存在重叠，所述第一开窗和所述第二开窗被配置为供一传热件穿过，使得所述传热件与所述第一部件之间实现热传导。
  11. 如权利要求1所述的装载机构，其特征在于，所述装载机构还包括操作件，所述操作件包括转动连接于所述安装座的转动部，所述转动部还连接于所述装载台，所述转动部被配置为在相较于所述安装座转动时，带动所述装载台沿着所述第一方向运动。
  12. 如权利要求11所述的装载机构，其特征在于，所述装载台的外侧设有传动部，所述安装座设有沿所述第一方向延伸的第一滑动槽，所述传动部可活动地穿过所述第一滑动槽并连接于所述转动部。
  13. 如权利要求12所述的装载机构，其特征在于，所述转动部设有沿着所述转动部的延伸方向延伸的第二滑动槽，所述传动部滑动地设于所述第二滑动槽内。
  14. 如权利要求11所述的装载机构，其特征在于，所述操作件还包括第一弹性件，所述第一弹性件连接于所述安装座和所述转动部。
  15. 如权利要求14所述的装载机构，其特征在于，所述第一弹性件包括第一臂和第二臂，所述第一臂连接于所述安装座，所述第二臂连接于所述转动部，所述第一弹性件被配置为当转动部带动所述装载台沿着所述第一方向朝向所述支撑面运动时处于压缩状态。
  16. 如权利要求11所述的装载机构，其特征在于，所述操作件还包括连接于所述转动部的操作部，所述操作部被配置为被按压时带动 所述转动部转动。
  17. 如权利要求16所述的装载机构，其特征在于，所述装载机构还包括安装于所述基座的锁扣件，所述锁扣件被配置为锁定所述操作部。
  18. 如权利要求17所述的装载机构，其特征在于，所述锁扣件包括固定于所述基座的座体和转动连接于所述座体的锁扣部，所述锁扣部被配置为锁定所述操作部。
  19. 如权利要求18所述的装载机构，其特征在于，所述锁扣部包括转动连接于所述座体的本体和凸设于所述本体的舌部，所述舌部包括垂直于所述本体所在平面的锁定面，所述锁定面被配置为平行于所述支撑面时锁定所述操作部。
  20. 如权利要求19所述的装载机构，其特征在于，所述舌部还包括相较于所述支撑面倾斜设置的倾斜面，在所述第一方向上，所述倾斜面相较于所述锁定面更远离所述支撑面，所述操作部被配置为被按压时抵持于所述倾斜面，使所述锁扣件背离所述操作部转动；所述锁扣件还包括第二弹性件，所述第二弹性件被配置为抵持于所述本体且当所述锁扣件背离所述操作部转动时发生弹性变形，所述第二弹性件的弹性回复力使所述锁定面锁定所述操作部。
  21. 如权利要求20所述的装载机构，其特征在于，所述第二弹性件包括第三臂和第四臂，所述第三臂弹性抵持于所述本体，所述第四臂的位置固定。
  22. 如权利要求1所述的装载机构，其特征在于，所述基座还包括设于所述支撑面上的导向轴，所述导向轴沿所述第一方向延伸，所述装载台设有导向孔，所述导向轴可活动地穿设于所述导向孔。
  23. 如权利要求22所述的装载机构，其特征在于，所述基座还包括绕设于所述导向轴的第三弹性件，所述第三弹性件弹性抵持于所述支撑面和所述装载台。
  24. 如权利要求6所述的装载机构，其特征在于，所述安装座包括第一安装部和两个相对设置的第二安装部，所述第一安装部设于两个所述第二安装部之间，所述第一导向槽设于所述第一安装部，所述第二导向槽设于所述第二安装部，所述装载台至少部分设于所述第一安装部和所述第二安装部围设形成的空间内。
  25. 一种生化物质分析装置，包括第二部件，其特征在于，所述生化物质分析装置还包括如权利要求1至24中任一项所述的装载机构，所述第二部件设于所述装载机构的装载台中。
  26. 如权利要求25所述的生化物质分析装置，其特征在于，所述生化物质分析装置还包括传热件，所述传热件至少部分穿设于所述基座和所述装载台，所述传热件被配置为与所述第一部件直接或间接接触以实现热传导。
  27. 一种生化物质分析系统，包括第一部件，其特征在于，所述生化物质分析系统还包括如权利要求25或26所述的生化物质分析装置，所述第一部件被配置为放置于所述生化物质分析装置的装载机构的装载台中并与所述第二部件装配。
  28. 如权利要求27所述的生化物质分析系统，其特征在于，所述第一部件包括在所述第一方向上层叠设置的微流控芯片、检测芯片以及载板，所述检测芯片被配置为检测所述微流控芯片内的流体并产生相应的信号，所述载板被配置为与所述第二部件装配并将所述信号发送至所述第二部件。
PCT/CN2024/082038 2024-03-15 2024-03-15 装载机构、生化物质分析装置和生化物质分析系统 Pending WO2025189477A1 (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111168607A (zh) * 2020-01-19 2020-05-19 Oppo（重庆）智能科技有限公司 用于辅助电子设备壳体组装的夹具
CN212122274U (zh) * 2020-03-12 2020-12-11 南昌欧菲生物识别技术有限公司 一种压合装置
KR20210055407A (ko) * 2019-11-07 2021-05-17 김영석 비대칭 부재의 정렬-삽입 장치
CN218036874U (zh) * 2022-08-09 2022-12-13 蓝怡科技集团股份有限公司 一种试剂瓶装载机构及分析设备
CN220218223U (zh) * 2023-06-21 2023-12-22 鸿准精密模具（昆山）有限公司 装配装置

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Publication number Priority date Publication date Assignee Title
KR20210055407A (ko) * 2019-11-07 2021-05-17 김영석 비대칭 부재의 정렬-삽입 장치
CN111168607A (zh) * 2020-01-19 2020-05-19 Oppo（重庆）智能科技有限公司 用于辅助电子设备壳体组装的夹具
CN212122274U (zh) * 2020-03-12 2020-12-11 南昌欧菲生物识别技术有限公司 一种压合装置
CN218036874U (zh) * 2022-08-09 2022-12-13 蓝怡科技集团股份有限公司 一种试剂瓶装载机构及分析设备
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