WO2024098691A1 - 粒子放射治疗系统及粒子放射治疗系统的控制方法 - Google Patents

粒子放射治疗系统及粒子放射治疗系统的控制方法 Download PDF

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Publication number
WO2024098691A1
WO2024098691A1 PCT/CN2023/092464 CN2023092464W WO2024098691A1 WO 2024098691 A1 WO2024098691 A1 WO 2024098691A1 CN 2023092464 W CN2023092464 W CN 2023092464W WO 2024098691 A1 WO2024098691 A1 WO 2024098691A1
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Prior art keywords
particle beam
radiation
information
user
particle
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PCT/CN2023/092464
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English (en)
French (fr)
Inventor
宋云涛
陈永华
丁开忠
刘璐
曹海林
王雪华
李实�
冯汉升
Original Assignee
合肥中科离子医学技术装备有限公司
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Publication of WO2024098691A1 publication Critical patent/WO2024098691A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1071—Monitoring, verifying, controlling systems and methods for verifying the dose delivered by the treatment plan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N2005/1074—Details of the control system, e.g. user interfaces

Definitions

  • the present invention belongs to the technical field of radiation equipment, and in particular relates to a particle radiation therapy system and a control method of the particle radiation therapy system.
  • Particle radiation therapy is a form of external beam radiation therapy that uses high-energy proton, ion, electron or electron beams to treat tumors or other diseases. By using protons or positively charged particles to treat the patient's tumor area, the treatment can effectively protect nearby healthy tissue and significantly reduce side effects.
  • the process of particle radiotherapy is accompanied by a large amount of radiation.
  • the operation When the operation is abnormal, it will not only affect the patient's treatment effect, but may also cause damage to the operator or operating equipment.
  • the systems or equipment used for particle radiotherapy have higher safety and reliability requirements.
  • the present invention aims to solve at least one of the technical problems existing in the prior art.
  • the present invention provides a particle radiation therapy system and a control method of the particle radiation therapy system, which can accurately locate the patient and improve the safety and reliability of the system in many aspects.
  • the present invention provides a particle radiation therapy system, the system comprising:
  • the radiation room system comprising an imaging system, a motion system, a particle beam delivery system, and a safety system;
  • a treatment control system wherein the treatment control system is respectively connected to the imaging system, the motion system, the particle beam delivery system and the safety system, and the safety system is used to output a device interlock signal and a device alarm signal;
  • a particle beam supply system the particle beam supply system being connected to the treatment control system
  • the treatment control system includes a user interaction component, the user interaction component is used to receive the radiation treatment information of the second user input by the first user;
  • the imaging system is used to collect current imaging information of the second user's body part, and the current imaging information is used to align with the user imaging information of the radiotherapy information to determine the target radiation area of the second user;
  • the motion system is used to drive the particle beam delivery system to move to the target radiation area
  • the treatment control system is used to send beam scheduling request information to the particle beam supply system based on the radiotherapy information
  • the particle beam supply system is used to generate and distribute a target particle beam to the particle beam delivery system based on the beam scheduling request information;
  • the treatment control system is used to determine the scanning path information of the target radiation area based on the radiation treatment information, and control the particle beam delivery system to deliver the target particle beam according to the scanning path information.
  • the treatment control system controls the imaging system and the motion system to accurately locate the target radiation area, and then controls the particle beam supply system to provide a particle beam flow that meets the requirements, and controls the particle beam delivery system to deliver the particle beam, thereby improving the reliability of the particle radiation process.
  • the safety system performs real-time safety monitoring to improve the safety of the system in all aspects.
  • the treatment control system comprises:
  • the radiation room component corresponds to the radiation room system one by one, and the radiation room component is used to control the workflow in the radiation room system corresponding to the radiation room component;
  • a beam scheduling component wherein the beam scheduling component is connected to the particle beam supply system
  • An imaging registration component a motion component and a dose delivery component, wherein the imaging registration component is connected to the imaging system, the motion component is connected to the motion system, and the dose delivery component is connected to the particle beam delivery system.
  • the treatment control system includes a monitoring component, which is connected to the safety system.
  • the monitoring component is used to monitor the component status of the treatment control system and the sensor status of the radiology room system, and to process the equipment interlock signal and the equipment alarm signal output by the safety system.
  • the motion system includes a positioning device and a rotating frame, the rotating frame is installed on the positioning device, the particle beam delivery system includes a beam modulation device, the beam modulation device is installed on the rotating frame, the rotating frame is used to control the beam direction of the particle beam delivered by the beam modulation device, and the positioning device is used to drive the beam modulation device to move to the target radiation area.
  • the treatment control system comprises a user verification component, and the user verification component is used to verify the user identity of the first user or the second user.
  • the present invention provides a control method based on the above-mentioned particle radiation therapy system, the method comprising:
  • the particle beam delivery system is controlled to deliver the target particle beam flow generated and distributed by the particle beam supply system according to the scanning path information.
  • the treatment control system controls the imaging system and the motion system to accurately locate the target radiation area, and then controls the particle beam supply system to provide a particle beam flow that meets the requirements, and controls the particle beam delivery system to deliver, thereby improving the reliability of the particle radiation process.
  • the safety system performs real-time safety monitoring to improve the safety of the system in all aspects.
  • obtaining the radiotherapy information of the second user includes:
  • the controlling image system to collect current image information of the second user's body part includes:
  • the controlling particle beam delivery system delivers the target particle beam flow generated and distributed by the particle beam supply system according to the scanning path information, including:
  • the particle beam delivery system is controlled to deliver the target particle beam according to the scanning path information.
  • control motion system drives the particle beam delivery system to move to the target radiation area, including:
  • the motion system is controlled to drive the particle beam delivery system to move to the target radiation area.
  • the controlling particle beam delivery system to deliver the target particle beam generated and distributed by the particle beam supply system according to the scanning path information includes:
  • the particle beam delivery system is controlled according to the The target particle beam is delivered according to the scanning path information.
  • the method further includes:
  • the radiation room system is controlled to enter a collision handling mode, and the equipment of the motion system performs jog operation at a safe speed in the collision handling mode.
  • the present invention provides an electronic device comprising a memory, a processor, and a computer program stored in the memory and executable on the processor, wherein when the processor executes the computer program, the control method of the particle radiation therapy system as described in the first aspect above is implemented.
  • the present invention provides a non-transitory computer-readable storage medium having a computer program stored thereon, wherein the computer program, when executed by a processor, implements the control method of the particle radiation therapy system as described in the first aspect above.
  • the treatment control system controls the imaging system and motion system to accurately locate the target radiation area, and then controls the particle beam supply system to provide a particle beam flow that meets the requirements, and controls the particle beam delivery system to deliver the particle beam, thereby improving the reliability of the particle radiation process.
  • the safety system performs real-time safety monitoring to improve the safety of the system in all aspects.
  • the treatment control system and the safety system have anti-collision functions.
  • the safety system detects a collision, it sends collision information to the monitoring component of the treatment control system.
  • the treatment control system can display a collision warning in the user interaction component.
  • the treatment control system also controls the radiation room system where the collision occurs to enter a collision processing mode. In the collision processing mode, the equipment of the motion system performs jog operation at a pre-configured safety speed to prevent further aggravation of the collision accident and improve system safety.
  • the user identity of the first user who controls the particle beam delivery and the user identity of the second user who receives the particle beam delivery are correct, and the target radiation area and the requested target particle beam flow determined by the treatment control system are accurate, thereby improving the reliability of the particle radiation therapy process of the particle radiation therapy system.
  • FIG1 is a schematic diagram of the structure of a particle radiation therapy system provided by an embodiment of the present invention.
  • FIG2 is a schematic flow chart of a control method for a particle radiation therapy system according to an embodiment of the present invention
  • FIG3 is a schematic diagram of one of the operation flow charts of the particle radiation therapy system provided by an embodiment of the present invention.
  • FIG4 is a second schematic diagram of the operation flow of the particle radiation therapy system provided by an embodiment of the present invention.
  • FIG. 5 is a schematic diagram of the structure of an electronic device provided by an embodiment of the present invention.
  • Reference numerals 100 particle radiotherapy system; 110: treatment control system; 111: user interaction component; 112: radiation room component; 113: beam scheduling component; 114: dose delivery component; 115: monitoring component; 116: imaging registration component; 117: motion component; 118: user verification component; 130: particle beam supply system; 140: particle beam delivery system; 150: safety system; 160: imaging system; 170: exercise system; 500: electronic device; 501: processor; 502: memory.
  • first, second, etc. in the specification and claims of the present invention are used to distinguish similar objects, and are not used to describe a specific order or sequence. It should be understood that the data used in this way can be interchangeable under appropriate circumstances, so that the embodiments of the present invention can be implemented in an order other than those illustrated or described herein, and the objects distinguished by "first”, “second”, etc. are generally of the same type, and the number of objects is not limited.
  • the first object can be one or more.
  • “and/or” in the specification and claims represents at least one of the connected objects, and the character “/" generally indicates that the objects associated with each other are in an "or” relationship.
  • the particle radiation therapy system 100 provided in the embodiment of the present invention includes: at least one radiation room system, a treatment control system 110 and a particle beam supply system 130 ;
  • Each radiation room system includes an imaging system 160 , a motion system 170 , a particle beam delivery system 140 and a safety system 150 .
  • multiple radiation rooms may be provided to perform particle radiotherapy, one for each radiation room.
  • the treatment control system 110 is used to coordinate the entire particle radiation therapy process of the particle radiation therapy system 100 and the required software and hardware resources.
  • the treatment control system 110 is respectively connected to the imaging system 160, the motion system 170, the particle beam delivery system 140 and the safety system 150 in the radiation room system. Based on the image registration result of the imaging system 160, the motion system 170 can be controlled to accurately position the patient, and the particle beam delivery system 140 can be controlled to complete the particle beam delivery to achieve the treatment purpose.
  • the safety system 150 is used to output equipment interlock signals and equipment alarm signals, and to perform real-time safety monitoring of the imaging system 160, the motion system 170 and the particle beam delivery system 140 in the radiology room system.
  • the safety system 150 is used to process the device interlock signal and the device alarm signal, and upload the device interlock signal and the device alarm signal to the treatment control system 110.
  • the device interlock signal refers to the interlock signal between various devices in the radiology room system.
  • the device interlock signal processed by the safety system 150 can realize the mutual restriction of the actions between various devices in the radiology room system, thereby improving the safety of the radiology room system.
  • the equipment alarm signal refers to the alarm signal for monitoring the operating status of each device in the radiology room system.
  • the equipment alarm signal processed by the safety system 150 can perform safety monitoring of each device in the radiology room system, issue real-time alarms, and improve the safety of the radiology room system.
  • the safety system 150 can promptly sound an alarm and take corresponding protective measures based on the interlocking relationship between the various devices.
  • the particle beam supply system 130 is connected to the treatment control system 110 .
  • the treatment control system 110 can output beam scheduling and beam request information to the particle beam supply system 130 .
  • the particle beam supply system 130 is used to provide a particle beam that meets the requirements.
  • the treatment control system 110 includes a user interaction component 111, and the user interaction component 111 is used to receive the radiation treatment information of the second user input by a first user.
  • the first user is a physician or physicist who can operate the particle radiation therapy system 100 and control the particle radiation therapy process
  • the second user is a patient who receives the particle beam delivery.
  • the radiation therapy information of the second user includes the identity information of the second user, the location information of the lesion site, the treatment plan information, and the like.
  • the user interaction component 111 may be a graphical user interface, which has the functions of displaying information and accepting input.
  • the user interaction component 111 is an important component for interacting with the user.
  • the graphical user interface may include a general graphical user interface, a clinical graphical user interface, a login screen, a GUI launcher and other parts.
  • the graphical user interface may also include a debugging graphical user interface for displaying the radiation therapy plan information of the second user, the information of the second user currently receiving particle beam delivery in the radiation room, the treatment status and the status of each system in the radiation room system.
  • the user interaction component 111 allows the first user to perform workflow activities, such as configuring, monitoring the system, verifying, moving equipment, and operating various systems in the radiology room system.
  • the user interaction component 111 can also display the device interlock signal and the device alarm signal processed by the security system 150, and can adjust and control each device in real time according to the status of the device interlock signal and the device alarm signal.
  • the imaging system 160 is used to collect current imaging information of the second user's body part, and the current imaging information is used to align with the user imaging information of the radiotherapy information to determine the target radiation area of the second user.
  • the imaging system 160 can collect imaging information of the patient's lesion site (i.e., current imaging information), and compare it with the patient's original imaging information (i.e., user imaging information of radiotherapy information) to accurately locate the area of the patient that needs particle radiotherapy.
  • imaging information of the patient's lesion site i.e., current imaging information
  • patient's original imaging information i.e., user imaging information of radiotherapy information
  • the motion system 170 is used to drive the particle beam delivery system 140 to move to the target radiation area.
  • the treatment control system 110 can control the motion system 170 to move to drive the particle beam delivery system 140 to move to the target radiation area.
  • the motion system 170 can not only perform position control of the treatment control system 110 , but also provide real-time feedback of the position status of the motion system 170 and the particle beam delivery system 140 to the treatment control system 110 .
  • the treatment control system 110 is used to send beam scheduling request information to the particle beam supply system 130 based on the radiotherapy information; the particle beam supply system 130 is used to generate and distribute the target particle beam to the particle beam delivery system 140 based on the beam scheduling request information.
  • the beam scheduling request information includes the dose information of the particle beam, and the particle beam supply system 130 generates a target particle beam of a corresponding dose according to the beam scheduling request information.
  • the treatment control system 110 sends beam scheduling request information to the particle beam supply system 130 based on the radiation treatment information of the patient in a certain radiation room.
  • the particle beam supply system 130 generates the target particle beam based on the beam scheduling request information and distributes the target particle beam to the particle beam delivery system 140 of the radiation room.
  • the treatment control system 110 is used to determine the scanning path information of the target radiation area based on the radiation treatment information, and control the particle beam delivery system 140 to deliver the target particle beam according to the scanning path information.
  • the particle beam delivery system 140 can perform pencil beam scanning according to the scanning path information to accurately deliver the target particle beam.
  • the particle radiation therapy system 100 is a cyclotron proton therapy system.
  • the treatment control system 110 of the cyclotron proton therapy system controls the particle beam supply system 130, that is, the accelerator, to provide a particle beam flow that meets the requirements, and controls the imaging system 160 and the operation system 161 in the radiation room.
  • the motion system 170 accurately positions the patient, and finally controls the particle beam delivery system 140 to deliver the particle beam, and controls the beam direction and dose with high precision so that the particle beam reaches the tumor target area to achieve the treatment purpose.
  • the treatment control system 110 controls the imaging system 160 and the motion system 170 to accurately locate the target radiation area, and then controls the particle beam supply system 130 to provide a particle beam flow that meets the requirements, and controls the particle beam delivery system 140 to deliver, thereby improving the reliability of the particle radiation process.
  • the safety system 150 performs real-time safety monitoring to improve the safety of the system in multiple aspects.
  • the therapy control system 110 includes:
  • the radiation room component 112 corresponds to the radiation room system one by one, and the radiation room component 112 is used to control the workflow in the radiation room system corresponding to the radiation room component 112;
  • a beam scheduling component 113 is connected to a particle beam supply system 130;
  • the beam scheduling component 113 manages the particle beam supply system 130 to achieve the allocation and scheduling of particle beam requests.
  • the beam scheduling component 113 only runs one instance of the particle beam supply system 130 to control the particle beam supply system 130 to provide particle beam resources for multiple radiation room systems.
  • the motion component 117 is connected to the motion system 170 and interacts with the motion system 170 to control various devices of the motion system 170 in the radiology room.
  • the motion component 117 can include a motion coordination module, an axial motion module, a path planning module and an optical tracking module, and has functions such as motion coordination, multi-axis motion, single-axis motion, path planning and optical tracking, which can achieve high-precision control of each device of the motion system 170.
  • the radiation room component 112 is the core of the treatment control system 110.
  • Each radiation room component 112 manages the workflow of the corresponding radiation room system and includes a workflow engine service.
  • the workflow engine service includes a workflow engine and a workflow description.
  • the workflow engine coordinates the workflows of various systems in the radiation room system in a single radiation room. Each radiation room can execute workflows independently of other radiation rooms.
  • the radiation room component 112 is not connected to external systems such as the particle beam supply system 130.
  • the imaging registration component 116 is connected to the imaging system 160 and interacts with the imaging system 160 to accurately locate the target radiation area where the second user needs to undergo particle radiation therapy by performing registration and comparison between the current image information and the user image information of the radiation therapy information.
  • the dose delivery component 114 is connected to the particle beam delivery system 140 and interacts with the particle beam delivery system 140 .
  • the dose delivery component 114 is used to manage the particle beam dose delivery process.
  • the treatment control system 110 may include a monitoring component 115, which is connected to the safety system 150.
  • the monitoring component 115 is used to monitor the component status of the treatment control system 110 and the sensor status of the radiation room system, and to process the equipment interlock signal and equipment alarm signal output by the safety system 150.
  • the monitoring component 115 is used to monitor the component status corresponding to each system connected to the treatment control system 110 .
  • the monitoring component 115 can monitor the component status of the imaging registration component 116 , the motion component 117 , the dose delivery component 114 and the beam scheduling component 113 .
  • the monitoring component 115 can also monitor the real-time monitoring status of sensors installed in each system in the radiation room system.
  • the particle beam delivery system 140 is provided with a radiation sensor.
  • the radiation sensor detects that the radiation value of the surrounding environment outside the target radiation area exceeds the corresponding safety threshold, and feeds back to the monitoring component 115 to alert the risk of leakage.
  • the monitoring component 115 can be used to read and process the equipment interlocking signal and equipment alarm signal from the safety system 150. When a system in the radiology room system fails, the relevant system or equipment is interlocked in real time and relevant detailed information is provided.
  • the treatment control system 110 and the safety system 150 have anti-collision functions.
  • the safety system 150 detects a collision, it sends collision information to the monitoring component 115 of the treatment control system 110.
  • the treatment control system 110 can display a collision warning in the user interaction component 111.
  • the treatment control system 110 also controls the radiation room system where the collision occurs to enter a collision processing mode. In the collision processing mode, the equipment of the motion system 170 performs jog operation at a pre-configured safety speed to prevent further aggravation of the collision accident and improve system safety.
  • the motion system 170 includes a positioning device and a rotating frame, the rotating frame is installed on the positioning device, the particle beam delivery system 140 includes a beam modulation device, the beam modulation device is installed on the rotating frame, the rotating frame is used to control the beam direction of the particle beam delivered by the beam modulation device, and the positioning device is used to drive the beam modulation device to move to the target radiation area.
  • the positioning device, the rotating gantry and the beam modulation device are controlled by the treatment control system 110, wherein the positioning device can be used for positioning the second user.
  • the positioning device is a treatment bed that can be moved and raised and lowered. By controlling the movement and raising and lowering of the treatment bed, the second user on the treatment bed can be placed in an appropriate position.
  • the treatment control system 110 controls the rotating gantry to adjust the beam direction of the particle beam delivered by the beam modulation device.
  • the treatment control system 110 controls the beam modulation device to control the dose and delivery speed of the delivered particle beam.
  • the treatment control system 110 may further include a user verification component 118 for verifying the user identity of the first user or the second user.
  • the workflow of the first user operating the particle radiotherapy system 100 may include starting a session, installing and verifying auxiliary equipment, selecting and opening an irradiation field of the second user (the target radiation area where particle beam delivery is required), controlling the positioning device to move to the second user's upper bed position, verifying the second user's information, performing rough positioning of the second user, clearing the imaging area that will affect the system, performing image capture, image registration, confirming the registration results, positioning correction of the second user, rotating the gantry to drive the beam modulation device to move to the target treatment area, clearing the radiation room, confirming the second user's radiotherapy information by the first user, requesting the target particle beam, delivering the target particle beam, completing the target particle beam delivery, executing the next irradiation field or the second user getting out of bed, and closing the session to end the treatment.
  • a specific embodiment of the working process of the particle radiation therapy system 100 is introduced below.
  • the first user selects a working mode, enters a user name and password, enters the treatment control system 110 , and opens a session.
  • the opened session includes patient (ie, second user) information and treatment plan information.
  • an irradiation field is selected and opened.
  • the treatment control system 110 will send the irradiation field information to the particle beam delivery system 140 for verification. If the verification fails, the process cannot continue and an irradiation field that meets the requirements must be reopened.
  • the doctor and the patient enter the radiology room.
  • the doctor controls the treatment bed to move to the upper bed position and verifies whether the patient information is consistent with the patient information on the treatment control system 110. If not, the process cannot continue and the session corresponding to the patient needs to be re-acquired.
  • the patient gets on the bed and fixes the body position.
  • the physician controls the treatment bed to move to the isocenter position marked by the laser to complete the rough positioning of the patient.
  • the imaging area is cleared, and the imaging system 160 performs image capture and image registration.
  • the imaging system 160 will send the registration result to the treatment control system 110.
  • a physician with corresponding authority is required to confirm the registration result. If the registration result exceeds the limit configured in the configuration file, the confirmation fails and the process cannot be continued.
  • the imaging and image registration need to be re-executed.
  • the physician calibrates the position of the treatment bed and controls it to move to the treatment position, and controls the rotating gantry and beam modulator to move to the treatment position.
  • the physician clears the radiology room, and the physicist cross-checks the prescription information in the radiotherapy information displayed on the graphical user interface of the treatment control system 110, and confirms the treatment plan. If the treatment plan has deviations and is not confirmed, the current treatment process ends.
  • the physician requests a beam on the treatment control system 110.
  • the beam scheduling component 113 of the treatment control system 110 schedules the accelerator and transport line of the particle beam supply system 130.
  • the particle beam delivery system 140 controls the beam to start delivery. After the beam ends, the next irradiation field is executed or the patient gets out of bed. Finally, the session is closed to end the treatment.
  • the execution subject of the control method may be a treatment control system 110 of the particle radiation therapy system 100 .
  • the control method of the particle radiation therapy system 100 may be applied to a terminal, and may be specifically executed by hardware or software in the terminal.
  • the terminal includes, but is not limited to, a portable communication device such as a mobile phone or tablet computer with a touch-sensitive surface (e.g., a touch screen display and/or a touch pad). It should also be understood that in some embodiments, the terminal may not be a portable communication device, but a desktop computer with a touch-sensitive surface (e.g., a touch screen display and/or a touch pad).
  • a portable communication device such as a mobile phone or tablet computer with a touch-sensitive surface (e.g., a touch screen display and/or a touch pad).
  • a touch-sensitive surface e.g., a touch screen display and/or a touch pad
  • a terminal including a display and a touch-sensitive surface is described.
  • the terminal may include one or more other physical user interface devices such as a physical keyboard, a mouse and a joystick.
  • the control method of the particle radiation therapy system 100 includes steps 210 to 270 .
  • Step 210 Obtain radiotherapy information of the second user.
  • Step 220 controlling the imaging system 160 to collect current imaging information of the second user's body part
  • Step 230 performing registration based on the current image information and the user image information of the radiotherapy information to determine the target radiation area of the second user;
  • Step 240 controlling the motion system 170 to drive the particle beam delivery system 140 to move to the target radiation area
  • Step 250 Send beam scheduling request information to the particle beam supply system 130 based on the radiotherapy information
  • Step 260 Determine scanning path information of the target radiation area based on the radiation therapy information
  • Step 270 Control the particle beam delivery system 140 to deliver the target particle beam generated and distributed by the particle beam supply system 130 according to the scanning path information.
  • control method of the particle radiation therapy system 100 is strictly executed in sequence, and if the previous step is not executed or failed, the process cannot be continued.
  • the treatment control system 110 controls the imaging system 160 and the motion system 170 to accurately locate the target radiation area, and then controls the particle beam supply system 130 to provide a particle beam flow that meets the requirements, and controls the particle beam delivery system 140 to deliver, thereby improving the reliability of the particle radiation process.
  • the safety system 150 performs real-time safety monitoring to improve the safety of the system in multiple aspects.
  • step 210 obtaining the radiation therapy information of the second user, includes:
  • Step 220 controlling the imaging system 160 to collect current imaging information of the second user's body part, including:
  • the imaging system 160 is controlled to collect current imaging information
  • Step 270 controlling the particle beam delivery system 140 to deliver the target particle beam generated and distributed by the particle beam supply system 130 according to the scanning path information, including:
  • the particle beam delivery system 140 is controlled to deliver the target particle beam according to the scanning path information.
  • identity authentication authorization is required. If the first user's identity authentication is passed and it is confirmed that the first user is a user who can operate the treatment control system 110, the radiation therapy information of the second user is obtained to ensure the reliability of the operator of the treatment control system 110.
  • the imaging system 160 collects the current image information
  • the image is taken to collect the current image information of the second user, so as to avoid other users interfering with the collection of the current image information of the second user and ensure the accuracy of the current image information of the second user.
  • the beam delivery can be executed.
  • the target particle beam is delivered to the corresponding second user to ensure the treatment effect.
  • the radiation room is cleared to ensure that other users will not be affected by the radiation of the particle beam, thereby improving the safety of the system.
  • step 240 controlling the motion system 170 to drive the particle beam delivery system 140 to move to the target radiation area, includes:
  • the motion system 170 is controlled to drive the particle beam delivery system 140 to move to the target radiation area.
  • the motion system 170 can be controlled to drive the particle beam delivery system 140 to move to the target radiation area.
  • the registration rate threshold may be 98%. Only when the registration rate of the target radiation area is greater than 98%, the motion system 170 can be controlled to drive the particle beam delivery system 140 to move to the target radiation area, thereby ensuring the accuracy of the target radiation area and the reliability of the treatment process.
  • step 270 controlling the particle beam delivery system 140 to deliver the target particle beam generated and distributed by the particle beam supply system 130 according to the scanning path information, includes:
  • the particle beam delivery system 140 is controlled to deliver the target particle beam according to the scanning path information.
  • the particle beam delivery system 140 verifies the dose information of the target particle beam. If the dose exceeds a safe dose threshold, a high dose alarm is generated and the beam is not delivered.
  • the particle beam delivery system 140 is controlled to deliver the target particle beam according to the scanning path information to ensure the safety of the delivery of the target particle beam.
  • control method of the particle radiation therapy system 100 further includes:
  • the radiation room system is controlled to enter the collision handling mode, and the equipment of the motion system 170 performs jog operation at a safe speed in the collision handling mode.
  • the treatment control system 110 and the safety system 150 have an anti-collision function.
  • the safety system 150 detects a collision in the radiology room system, it outputs corresponding collision alarm information and controls the radiology room system where the collision occurs to enter a collision processing mode.
  • the equipment of the motion system 170 performs jog operation at a pre-configured safety speed to prevent further aggravation of the collision accident and improve system safety.
  • the movement of the equipment of the motion system 170 is not allowed under any of the following conditions: the user is not logged in; the security system 150 is interlocked and alarmed; the beam in the radiation room is queued or irradiation is being performed; the irradiation in the radiation room is in a paused state; the particle beam delivery system 140 is in treatment mode.
  • step 410 when a user logs into the treatment control system 110 , identity authentication and authorization are performed.
  • the user is a physician (ie, a first user) who can operate the treatment control system 110 and control the workflow.
  • identity authentication and authorization are performed, including identity authentication and authorization for physicians and identity authentication for patients in the radiology room.
  • Step 420 After the image area is cleared, image capture is performed.
  • the optical tracking system and beam modulation equipment are installed, and the irradiation field is selected.
  • the physician and the patient enter the radiation room.
  • the physician operates the control unit to move the treatment bed to the upper bed position and verifies whether the patient information is consistent with the patient information on the treatment control system 110.
  • the patient gets on the bed and fixes the body position, and the doctor controls the treatment bed to move to the isocenter position marked by the laser to complete the rough positioning of the patient.
  • the imaging area is cleared, and the imaging system 160 performs image capture and image registration.
  • Step 430 The specific user authority confirms and authorizes the registration result uploaded by the imaging system 160 .
  • the imaging system After the registration is completed, the imaging system will send the registration result to the treatment control system 110. At this time, a physician with corresponding specific user permissions is required to confirm the registration result. If the registration result is lower than the limit configured in the configuration file, the confirmation fails and the process cannot continue. The imaging and image registration need to be re-executed.
  • Step 440 Apply the registration result and move the treatment couch to the treatment position.
  • the treatment control system 110 allows the user to move the treatment couch to the treatment position only after the registration result is applied; when the registration result is lower than the registration rate threshold configured in the configuration file, the user cannot confirm on the treatment control system 110, and the current workflow cannot continue. If you want to continue, you need to re-execute the imaging registration.
  • Step 450 Confirm the patient information and treatment plan.
  • Step 460 After the radiation room is cleared, beam delivery is performed.
  • the particle beam delivery system 140 verifies the dose information from the treatment control system 110 . If the dose exceeds a safe dose threshold, a high dose alarm is generated and beam delivery is not performed.
  • the treatment control system 110 and the safety system 150 have an anti-collision function.
  • the safety system 150 detects a collision, it sends collision information to the treatment control system 110.
  • the treatment control system 110 will display a warning and enter a collision handling mode. In the collision handling mode, the equipment of the motion system 170 is only allowed to jog at a pre-configured safety speed.
  • the treatment control system 110 does not allow the movement of the equipment of the motion system 170 under any of the following conditions: the user is not logged in; the safety system 150 is interlocked and alarmed; the beam in the radiation room is queued or irradiation is being performed; the irradiation in the radiation room is in a paused state; the particle beam delivery system 140 is in treatment mode.
  • an embodiment of the present invention further provides an electronic device 500, comprising a processor 501, a memory 502, and a computer program stored in the memory 502 and executable on the processor 501.
  • an electronic device 500 comprising a processor 501, a memory 502, and a computer program stored in the memory 502 and executable on the processor 501.
  • the program is executed by the processor 501, each process of the control method embodiment of the above-mentioned particle radiation therapy system 100 is implemented, and the same technical effect can be achieved. To avoid repetition, it will not be described here.
  • An embodiment of the present invention further provides a non-transitory computer-readable storage medium, on which a computer program is stored.
  • a computer program is executed by a processor, the various processes of the control method embodiment of the above-mentioned particle radiation therapy system 100 are implemented, and the same technical effect can be achieved. To avoid repetition, it will not be repeated here.
  • the processor is the processor in the electronic device described in the above embodiment.
  • the readable storage medium includes a computer readable storage medium, such as a computer read-only memory ROM, a random access memory RAM, a magnetic disk or an optical disk.
  • An embodiment of the present invention further provides a computer program product, including a computer program, which implements the control method of the particle radiation therapy system 100 when executed by a processor.
  • the processor is the processor in the electronic device described in the above embodiment.
  • the readable storage medium includes a computer readable storage medium, such as a computer read-only memory ROM, a random access memory RAM, a magnetic disk or an optical disk.
  • the technical solution of the present invention in essence, or the part that contributes to the prior art, can be embodied in the form of a computer software product, which is stored in a storage medium (such as ROM/RAM, a magnetic disk, or an optical disk), and includes a number of instructions for enabling a terminal (which can be a mobile phone, a computer, a server, or a network device, etc.) to execute the methods described in each embodiment of the present invention.
  • a storage medium such as ROM/RAM, a magnetic disk, or an optical disk

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Abstract

本发明公开了一种粒子放射治疗系统及粒子放射治疗系统的控制方法，属于放射设备技术领域。该系统包括：至少一个放射室系统，放射室系统包括影像系统、运动系统、粒子束投递系统和安全系统；治疗控制系统，治疗控制系统分别与影像系统、运动系统、粒子束投递系统和安全系统连接，安全系统用于输出设备联锁信号和设备报警信号；粒子束供应系统，粒子束供应系统与治疗控制系统连接；治疗控制系统包括用户交互组件。该系统通过治疗控制系统控制影像系统和运动系统精确定位目标放射区域，再控制粒子束供应系统提供满足要求的粒子束流，粒子束投递系统进行投递，安全系统进行实时安全监测，多方位提高系统的可靠性和安全性。

Description

粒子放射治疗系统及粒子放射治疗系统的控制方法 技术领域
本发明属于放射设备技术领域，尤其涉及一种粒子放射治疗系统及粒子放射治疗系统的控制方法。
背景技术
粒子放射治疗是一种使用高能质子、离子、电子或电子射束来治疗肿瘤或其他疾病的外部射束放射治疗形式。通过使用来自质子或带正电粒子，对准患者的肿瘤区域进行治疗，治疗同时可以有效保护附近的健康组织，较大幅度地减少副作用。
粒子放射治疗的过程中伴随着大量的辐射，当操作出现异常时，不仅会影响到患者的治疗效果，对操作人员或操作设备也可能造成损伤，相较于其他工业系统，用于粒子放射治疗的系统或设备有着更高的安全性要求和可靠性要求。
发明内容
本发明旨在至少解决现有技术中存在的技术问题之一。为此，本发明提出一种粒子放射治疗系统及粒子放射治疗系统的控制方法，可以精确定位患者，多方面提高系统的安全性和可靠性。
第一方面，本发明提供了一种粒子放射治疗系统，该系统包括：
至少一个放射室系统，所述放射室系统包括影像系统、运动系统、粒子束投递系统和安全系统；
治疗控制系统，所述治疗控制系统分别与所述影像系统、所述运动系统、所述粒子束投递系统和所述安全系统连接，所述安全系统用于输出设备联锁信号和设备报警信号；
粒子束供应系统，所述粒子束供应系统与所述治疗控制系统连接；
所述治疗控制系统包括用户交互组件，所述用户交互组件用于接收第一用户输入的第二用户的放射治疗信息；
所述影像系统用于采集所述第二用户身体部位的当前影像信息，所述当前影像信息用于与所述放射治疗信息的用户影像信息进行配准，确定所述第二用户的目标放射区域；
所述运动系统用于驱动所述粒子束投递系统运动至所述目标放射区域；
所述治疗控制系统用于基于所述放射治疗信息，向所述粒子束供应系统发送束流调度请求信息；
所述粒子束供应系统用于基于所述束流调度请求信息，生成并分配目标粒子束流至所述粒子束投递系统；
所述治疗控制系统用于基于所述放射治疗信息，确定所述目标放射区域的扫描路径信息，控制所述粒子束投递系统根据所述扫描路径信息投放所述目标粒子束流。
根据本发明的粒子放射治疗系统，通过治疗控制系统控制影像系统和运动系统精确定位目标放射区域，再控制粒子束供应系统提供满足要求的粒子束流，控制粒子束投递系统进行投递，提升粒子放射过程的可靠性，同时安全系统进行实时安全监测，多方位提高系统的安全性。
根据本发明的一个实施例，所述治疗控制系统包括：
至少一个放射室组件，所述放射室组件与所述放射室系统一一对应，所述放射室组件用于控制所述放射室组件对应的所述放射室系统内的工作流程；
束流调度组件，所述束流调度组件与所述粒子束供应系统连接；
成像配准组件、运动组件和剂量投递组件，所述成像配准组件与所述影像系统连接，所述运动组件与所述运动系统连接，所述剂量投递组件与所述粒子束投递系统连接。
根据本发明的一个实施例，所述治疗控制系统包括监控组件，所述监控组件与所述安全系统连接，所述监控组件用于监控所述治疗控制系统的组件状态和所述放射室系统的传感器状态，以及处理所述安全系统输出的所述设备联锁信号和所述设备报警信号。
根据本发明的一个实施例，所述运动系统包括摆位设备和旋转机架，所述旋转机架安装于所述摆位设备，所述粒子束投递系统包括束流调制设备，所述束流调制设备安装于所述旋转机架，所述旋转机架用于控制所述束流调制设备投放粒子束流的束流方向，所述摆位设备用于驱动所述束流调制设备运动至所述目标放射区域。
根据本发明的一个实施例，所述治疗控制系统包括用户验证组件，所述用户验证组件用于对所述第一用户或所述第二用户的用户身份进行验证。
第二方面，本发明提供了一种基于上述粒子放射治疗系统的控制方法，该方法包括：
获取第二用户的放射治疗信息；
控制影像系统采集所述第二用户身体部位的当前影像信息；
基于所述当前影像信息和所述放射治疗信息的用户影像信息进行配准，确定所述第二用户的目标放射区域；
控制运动系统驱动粒子束投递系统运动至所述目标放射区域；
基于所述放射治疗信息，向所述粒子束供应系统发送束流调度请求信息；
基于所述放射治疗信息，确定所述目标放射区域的扫描路径信息；
控制粒子束投递系统根据所述扫描路径信息投放所述粒子束供应系统生成并分配的目标粒子束流。
根据本发明的基于上述粒子放射治疗系统的控制方法，通过治疗控制系统控制影像系统和运动系统精确定位目标放射区域，再控制粒子束供应系统提供满足要求的粒子束流，控制粒子束投递系统进行投递，提升粒子放射过程的可靠性，同时安全系统进行实时安全监测，多方位提高系统的安全性。
根据本发明的一个实施例，所述获取第二用户的放射治疗信息，包括：
在第一用户的身份验证通过的情况下，获取所述第二用户的放射治疗信息；
所述控制影像系统采集所述第二用户身体部位的当前影像信息，包括：
在所述第二用户的身份验证通过，且所述影像系统的拍摄区域清场的情况下，控制所述影像系统采集所述当前影像信息；
所述控制粒子束投递系统根据所述扫描路径信息投放所述粒子束供应系统生成并分配的目标粒子束流，包括：
在所述放射室系统清场，且接收到所述第一用户输入的放射确认信息的情况下，控制所述粒子束投递系统根据所述扫描路径信息投放所述目标粒子束流。
根据本发明的一个实施例，所述控制运动系统驱动粒子束投递系统运动至所述目标放射区域，包括：
在所述目标放射区域的配准率大于配准率阈值的情况下，控制所述运动系统驱动所述粒子束投递系统运动至所述目标放射区域。
根据本发明的一个实施例，所述控制粒子束投递系统根据所述扫描路径信息投放所述粒子束供应系统生成并分配的目标粒子束流，包括：
在所述目标粒子束流的剂量小于剂量阈值的情况下，控制所述粒子束投递系统根据所 述扫描路径信息投放所述目标粒子束流。
根据本发明的一个实施例，所述方法还包括：
接收安全系统输出的所述放射室系统的碰撞报警信息；
控制所述放射室系统进入碰撞处理模式，所述运动系统的设备在所述碰撞处理模式下以安全速度进行点动运行。
第三方面，本发明提供了一种电子设备，包括存储器、处理器及存储在所述存储器上并可在所述处理器上运行的计算机程序，所述处理器执行所述计算机程序时实现如上述第一方面所述的粒子放射治疗系统的控制方法。
第四方面，本发明提供了一种非暂态计算机可读存储介质，其上存储有计算机程序，所述计算机程序被处理器执行时实现如上述第一方面所述的粒子放射治疗系统的控制方法。
本发明实施例中的上述一个或多个技术方案，至少具有如下技术效果之一：
通过治疗控制系统控制影像系统和运动系统精确定位目标放射区域，再控制粒子束供应系统提供满足要求的粒子束流，控制粒子束投递系统进行投递，提升粒子放射过程的可靠性，同时安全系统进行实时安全监测，多方位提高系统的安全性。
进一步的，治疗控制系统和安全系统具有防碰撞功能，当安全系统检测到发生碰撞时，向治疗控制系统的监控组件发送碰撞信息，治疗控制系统可以在用户交互组件显示碰撞警告，治疗控制系统同时控制发生碰撞的放射室系统进入碰撞处理模式，碰撞处理模式下，运动系统的设备以预先配置的安全速度进行点动运行，防止碰撞事故进一步加剧，提高系统安全性。
更进一步的，确保控制粒子束投放的第一用户的用户身份以及接受粒子束投放的第二用户的用户身份正确无误，治疗控制系统确定的目标放射区域和所请求的目标粒子束流准确，提升粒子放射治疗系统的粒子放射治疗流程的可靠性。
本发明的附加方面和优点将在下面的描述中部分给出，部分将从下面的描述中变得明显，或通过本发明的实践了解到。
附图说明
本发明的上述和/或附加的方面和优点从结合下面附图对实施例的描述中将变得明显 和容易理解，其中：
图1是本发明实施例提供的粒子放射治疗系统的结构示意图；
图2是本发明实施例提供的粒子放射治疗系统的控制方法的流程示意图；
图3是本发明实施例提供的粒子放射治疗系统的操作流程示意图之一；
图4是本发明实施例提供的粒子放射治疗系统的操作流程示意图之二；
图5是本发明实施例提供的电子设备的结构示意图。
附图标记
100：粒子放射治疗系统；110：治疗控制系统；111：用户交互组件；112：放射室组
件；113：束流调度组件；114：剂量投递组件；115：监控组件；116：成像配准组件；117：运动组件；118：用户验证组件；
130：粒子束供应系统；140：粒子束投递系统；150：安全系统；160：影像系统；170：
运动系统；
500：电子设备；501：处理器；502：存储器。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员获得的所有其他实施例，都属于本发明保护的范围。
本发明的说明书和权利要求书中的术语“第一”、“第二”等是用于区别类似的对象，而不用于描述特定的顺序或先后次序。应该理解这样使用的数据在适当情况下可以互换，以便本发明的实施例能够以除了在这里图示或描述的那些以外的顺序实施，且“第一”、“第二”等所区分的对象通常为一类，并不限定对象的个数，例如第一对象可以是一个，也可以是多个。此外，说明书以及权利要求中“和/或”表示所连接对象的至少其中之一，字符“/”，一般表示前后关联对象是一种“或”的关系。
下面结合附图，通过具体的实施例及其应用场景对本发明实施例提供的粒子放射治疗系统100和粒子放射治疗系统100的控制方法进行详细地说明。
如图1所述，本发明实施例提供的粒子放射治疗系统100包括：至少一个放射室系统、治疗控制系统110和粒子束供应系统130；
其中，每个放射室系统包括影像系统160、运动系统170、粒子束投递系统140和安全系统150。
可以理解的是，实际粒子放射治疗场景下，可以设置多个放射室，分别执行粒子放射治疗，每个放射室对应一个。
治疗控制系统110用于协调粒子放射治疗系统100的整个粒子放射治疗过程和所需的软硬件资源。
治疗控制系统110分别与放射室系统中的影像系统160、运动系统170、粒子束投递系统140和安全系统150连接，可以基于影像系统160的影像配准结果，控制运动系统170精准定位患者，控制粒子束投递系统140完成粒子束投递，实现治疗目的。
其中，安全系统150用于输出设备联锁信号和设备报警信号，对放射室系统中影像系统160、运动系统170和粒子束投递系统140进行实时的安全监控。
需要说明的是，安全系统150用于处理设备联锁信号和设备报警信号，并将设备联锁信号和设备报警信号上传至治疗控制系统110。
其中，设备联锁信号指放射室系统中各个设备之间的联锁信号，安全系统150所处理的设备联锁信号可以实现对放射室系统中各个设备间动作的互相制约，提升放射室系统的安全性。
设备报警信号指放射室系统中设备各自的运行状态监控的报警信号，安全系统150所处理的设备报警信号可以对放射室系统中各个设备进行安全监控，实时报警，提升放射室系统的安全性。
例如，当放射室系统中设备发生碰撞时，安全系统150能及时报警，并根据各个设备之间的联锁关系，做出相应的保护措施。
粒子束供应系统130与治疗控制系统110连接，治疗控制系统110可以向粒子束供应系统130输出束流调度和束流请求信息，粒子束供应系统130用于提供满足要求的粒子束流。
治疗控制系统110包括用户交互组件111，用户交互组件111用于接收第一用户输入的第二用户的放射治疗信息。
第一用户为可以操作粒子放射治疗系统100，控制粒子放射治疗过程的医师或物理师，第二用户为接受粒子束流投递的患者人员。
第二用户的放射治疗信息包括第二用户的身份信息、病灶部位的位置信息和治疗计划信息等。
在该实施例中，用户交互组件111可以为图形用户界面，图形用户界面具有显示信息和接受输入的功能。
用户交互组件111是与用户交互的重要组件，用户交互组件111为图形用户界面时，图形用户界面可以包括通用图形用户界面、临床图形用户界面、登录屏幕和GUI启动器等部分。
图形用户界面还可以包括调试图形用户界面，用于显示第二用户的放射治疗计划信息，当前正在放射室内接受粒子束投递的第二用户的信息、治疗状态和放射室系统中各系统状态。
用户交互组件111允许第一用户执行工作流活动，可以配置、监控系统，验证、移动设备，以及对放射室系统中各系统进行操作。
需要说明的是，用户交互组件111也可以显示安全系统150所处理的设备联锁信号和设备报警信号，可以根据设备联锁信号和设备报警信号的状态实时进行各个设备的调整控制。
影像系统160用于采集第二用户身体部位的当前影像信息，当前影像信息用于与放射治疗信息的用户影像信息进行配准，确定第二用户的目标放射区域。
影像系统160可以采集患者病灶部位的影像信息(即当前影像信息)，与患者原有的影像信息(即放射治疗信息的用户影像信息)做配准比对，精准定位患者需要进行粒子放射治疗的区域。
运动系统170用于驱动粒子束投递系统140运动至目标放射区域，治疗控制系统110可以控制运动系统170运动，以驱动粒子束投递系统140运动至目标放射区域。
其中，运动系统170不仅可以执行治疗控制系统110的位置控制，还可以实时向治疗控制系统110反馈运动系统170和粒子束投递系统140的位置状态。
治疗控制系统110用于基于放射治疗信息，向粒子束供应系统130发送束流调度请求信息；粒子束供应系统130用于基于束流调度请求信息，生成并分配目标粒子束流至粒子束投递系统140。
其中，束流调度请求信息包括粒子束的剂量信息，粒子束供应系统130根据束流调度请求信息，生成对应剂量的目标粒子束。
可以理解的是，当有多个放射室时，治疗控制系统110根据某一放射室的患者的放射治疗信息向粒子束供应系统130发送束流调度请求信息，粒子束供应系统130根据束流调度请求信息，生成目标粒子束流，并将目标粒子束流分配至该放射室的粒子束投递系统140。
治疗控制系统110用于基于放射治疗信息，确定目标放射区域的扫描路径信息，控制粒子束投递系统140根据扫描路径信息投放目标粒子束流。
在实际的执行中，粒子束投递系统140可以按照扫描路径信息进行笔形束扫描，将目标粒子束流准确投放。
以粒子放射治疗系统100是回旋加速器质子治疗系统为例。
在治疗过程中，回旋加速器质子治疗系统的治疗控制系统110一方面控制粒子束供应系统130即加速器提供满足要求的粒子束流，另一方面控制放射室内的影像系统160和运 动系统170精准定位患者，最后控制粒子束投递系统140投递，高精度控制束流方向和剂量，以使粒子束到达肿瘤靶区实现治疗目的。
根据本发明实施例提供的粒子放射治疗系统100，通过治疗控制系统110控制影像系统160和运动系统170精确定位目标放射区域，再控制粒子束供应系统130提供满足要求的粒子束流，控制粒子束投递系统140进行投递，提升粒子放射过程的可靠性，同时安全系统150进行实时安全监测，多方位提高系统的安全性。
在一些实施例中，治疗控制系统110包括：
至少一个放射室组件112，放射室组件112与放射室系统一一对应，放射室组件112用于控制放射室组件112对应的放射室系统内的工作流程；
束流调度组件113，束流调度组件113与粒子束供应系统130连接；
成像配准组件116、运动组件117和剂量投递组件114，成像配准组件116与影像系统160连接，运动组件117与运动系统170连接，剂量投递组件114与粒子束投递系统140连接。
束流调度组件113通过对粒子束供应系统130的管理，实现粒子束流请求的分配和调度，束流调度组件113只运行粒子束供应系统130一个实例，控制粒子束供应系统130为多个放射室系统提供粒子束流资源。
运动组件117与运动系统170连接，与运动系统170进行交互，用于控制放射室内的运动系统170的各个设备。
其中，运动组件117可以包括运动协调模块、轴向运动模块、路径规划模块和光学跟踪模块，具有运动协调、多轴运动、单轴运动、路径规划和光学跟踪等功能，可以实现对运动系统170的各个设备的高精度控制。
放射室组件112是治疗控制系统110的核心，每个放射室组件112管理对应的放射室系统的工作流，并包含工作流引擎服务，工作流引擎服务包括工作流引擎和工作流描述。
工作流引擎在单个放射室内协调放射室系统中各个系统的工作流程，每个放射室可以独立于其他放射室执行工作流程，放射室组件112不连接粒子束供应系统130等外部系统。
成像配准组件116连接影像系统160，与影像系统160交互，通过将当前影像信息和放射治疗信息的用户影像信息做配准比对，精准定位第二用户需要进行粒子放射治疗的目标放射区域。
剂量投递组件114与粒子束投递系统140连接，与粒子束投递系统140相交互，剂量投递组件114用于管理粒子束剂量投递流程。
在一些实施例中，治疗控制系统110可以包括监控组件115，监控组件115与安全系统150连接，监控组件115用于监控治疗控制系统110的组件状态和放射室系统的传感器状态，以及处理安全系统150输出的设备联锁信号和设备报警信号。
监控组件115用于监控治疗控制系统110所连接的各个系统对应的组件状态，监控组件115可以监控成像配准组件116、运动组件117、剂量投递组件114和束流调度组件113的组件状态。
监控组件115还可以监控放射室系统中各个系统设置的传感器的实时监测状态，例如，粒子束投递系统140设有辐射传感器，在粒子束投递系统140执行粒子束投递时，辐射传感器检测到目标放射区域外的周围环境的辐射值超过对应的安全阈值，反馈给监控组件115，提醒泄露风险。
监控组件115可以用于读取并处理来自安全系统150的设备联锁信号和设备报警信号，当放射室系统中的某系统出现故障时，实时联锁相关系统或设备，并提供相关的详细信息。
需要说明的是，治疗控制系统110和安全系统150具有防碰撞功能，当安全系统150检测到发生碰撞时，向治疗控制系统110的监控组件115发送碰撞信息，治疗控制系统110可以在用户交互组件111显示碰撞警告，治疗控制系统110同时控制发生碰撞的放射室系统进入碰撞处理模式，碰撞处理模式下，运动系统170的设备以预先配置的安全速度进行点动运行，防止碰撞事故进一步加剧，提高系统安全性。
在一些实施例中，运动系统170包括摆位设备和旋转机架，旋转机架安装于摆位设备，粒子束投递系统140包括束流调制设备，束流调制设备安装于旋转机架，旋转机架用于控制束流调制设备投放粒子束流的束流方向，摆位设备用于驱动束流调制设备运动至目标放射区域。
摆位设备、旋转机架和束流调制设备受到治疗控制系统110的控制，其中，摆位设备可以用于第二用户的摆位，例如，摆位设备为可以移动位置以及升降控制的治疗床，控制治疗床的移动和升降，可以将治疗床上的第二用户摆放至适当位置。
治疗控制系统110控制旋转机架，调整束流调制设备投放粒子束流的束流方向，治疗控制系统110控制束流调制设备，可以对投放粒子束的剂量和投放速度进行控制。
在一些实施例中，治疗控制系统110还可以包括用户验证组件118，用户验证组件118用于对第一用户或第二用户的用户身份进行验证。
可以理解的是，通过确保控制粒子束投放的第一用户的用户身份以及接受粒子束投放的第二用户的用户身份正确无误，提升了治疗控制系统110确定的目标放射区域和所请求的目标粒子束流的准确度，进而提升粒子放射治疗系统100的粒子放射治疗流程的可靠性。
第一用户操作粒子放射治疗系统100的工作流程可以包括开始会话，安装辅助设备并验证，选择并打开第二用户的一个照射野(需要进行粒子束投递的目标放射区域)，控制摆位设备运动到第二用户的上床位，验证第二用户的信息，进行第二用户的粗摆位，将影响系统的影像区清场，执行影像拍照，图像配准，配准结果确认，第二用户的摆位校正，旋转机架带动束流调制设备运动至目标治疗区域，将放射室清场，由第一用户确认第二用户的放射治疗信息，请求目标粒子束流，目标粒子束流投递，目标粒子束流投递结束，执行下个照射野或第二用户下床，关闭会话结束治疗。
下面介绍一个粒子放射治疗系统100工作流程的具体实施例。
如图3所示，第一用户选择工作模式，输入用户名密码，进入治疗控制系统110后，打开会话，打开的会话包括患者(即第二用户)信息和治疗计划信息。
然后安装光学追踪系统并验证，安装束流调制设备并验证，如果验证不通过，需重新安装验证，直到验证通过才能继续流程。
接下来选择并打开一个照射野，打开照射野的同时，治疗控制系统110会把该照射野信息发送给粒子束投递系统140进行验证，如验证不通过，则不能继续流程，需重新打开符合要求的照射野。
医师和患者进入放射室，医师操作控制治疗床运动到上床位并验证患者是否与治疗控制系统110上的患者信息一致，如不一致，不能继续流程，需重新获取该患者对应的会话。
如果相一致，患者上床并固定体位，医师控制治疗床运动到激光标记的等中心位，完成患者粗摆位。
然后，对影像区进行清场，影像系统160执行影像拍照和图像配准，配准完成后影像系统160会把配准结果发送给治疗控制系统110，此时需要相应权限的医师对该配准结果进行确认，如该配准结果超过配置文件中配置的限值，则确认失败，不能继续流程，需重新执行影像拍照和图像配准。
配置结果确认之后，医师对治疗床位置进行校正控制其运动到治疗位，控制旋转机架和束流调制设备运动到治疗位。医师对放射室进行清场，物理师交叉检查治疗控制系统110图形用户界面上显示的放射治疗信息中的处方信息，并确认治疗计划，如果治疗计划有偏差没有确认通过，则结束当前治疗流程。
治疗计划验证通过后，医师在治疗控制系统110上请求束流，治疗控制系统110的束流调度组件113对粒子束供应系统130的加速器和输运线进行调度，粒子束投递系统140控制束流开始投递，束流结束后，执行下个照射野或患者下床，最后关闭会话结束治疗。
下面介绍本发明提供的基于上述粒子放射治疗系统100的控制方法，该控制方法的执行主体可以为粒子放射治疗系统100的治疗控制系统110。
其中，粒子放射治疗系统100的控制方法可应用于终端，具体可由，终端中的硬件或软件执行。
该终端包括但不限于具有触摸敏感表面(例如，触摸屏显示器和/或触摸板)的移动电话或平板电脑等便携式通信设备。还应当理解的是，在某些实施例中，该终端可以不是便携式通信设备，而是具有触摸敏感表面(例如，触摸屏显示器和/或触摸板)的台式计算机。
以下各个实施例中，描述了包括显示器和触摸敏感表面的终端。然而，应当理解的是，终端可以包括诸如物理键盘、鼠标和控制杆的一个或多个其它物理用户接口设备。
如图2所示，该粒子放射治疗系统100的控制方法包括：步骤210至步骤270。
步骤210、获取第二用户的放射治疗信息。
步骤220、控制影像系统160采集第二用户身体部位的当前影像信息；
步骤230、基于当前影像信息和放射治疗信息的用户影像信息进行配准，确定第二用户的目标放射区域；
步骤240、控制运动系统170驱动粒子束投递系统140运动至目标放射区域；
步骤250、基于放射治疗信息，向粒子束供应系统130发送束流调度请求信息；
步骤260、基于放射治疗信息，确定目标放射区域的扫描路径信息；
步骤270、控制粒子束投递系统140根据扫描路径信息投放粒子束供应系统130生成并分配的目标粒子束流。
需要说明的是，粒子放射治疗系统100的控制方法严格按照顺序执行，如果前一步骤没有执行或没有通过，不能继续流程。
根据本发明的粒子放射治疗系统100的控制方法，通过治疗控制系统110控制影像系统160和运动系统170精确定位目标放射区域，再控制粒子束供应系统130提供满足要求的粒子束流，控制粒子束投递系统140进行投递，提升粒子放射过程的可靠性，同时安全系统150进行实时安全监测，多方位提高系统的安全性。
在一些实施例中，步骤210、获取第二用户的放射治疗信息，包括：
在第一用户的身份验证通过的情况下，获取第二用户的放射治疗信息；
步骤220、控制影像系统160采集第二用户身体部位的当前影像信息，包括：
在第二用户的身份验证通过，且影像系统160的拍摄区域清场的情况下，控制影像系统160采集当前影像信息；
步骤270、控制粒子束投递系统140根据扫描路径信息投放粒子束供应系统130生成并分配的目标粒子束流，包括：
在放射室系统清场，且接收到第一用户输入的放射确认信息的情况下，控制粒子束投递系统140根据扫描路径信息投放目标粒子束流。
在第一用户登录治疗控制系统110，需要进行身份验证授权，在第一用户的身份验证通过的情况下，确认第一用户是可以进行治疗控制系统110操作的用户后，再获取第二用户的放射治疗信息，保证治疗控制系统110操作人员的可靠性。
影像系统160采集当前影像信息时，在影像系统160所采集的影像区清场后，再执行影像拍照，采集第二用户的当前影像信息，避免其他用户干扰第二用户的当前影像信息的采集，保证第二用户的当前影像信息的准确性。
接收到第一用户输入的放射确认信息，对第二用户的信息和治疗计划进行确认，且保证放射室清场后，方能执行束流投递，目标粒子束流投递到对应的第二用户，保证治疗效果，放射室清场，确保其他用户不会受到粒子束流的辐射影响，提高系统的安全性。
在一些实施例中，步骤240、控制运动系统170驱动粒子束投递系统140运动至目标放射区域，包括：
在目标放射区域的配准率大于配准率阈值的情况下，控制运动系统170驱动粒子束投递系统140运动至目标放射区域。
在进行当前影像信息和放射治疗信息的用户影像信息的配准后，需要对影像系统160上传的配准结果进行确认，当配准结果目标放射区域的配准率大于配置文件中配置的配准率阈值时，才可以控制运动系统170驱动粒子束投递系统140运动至目标放射区域。
例如，配准率阈值可以为98％，只有目标放射区域的配准率大于98％，才可以控制运动系统170驱动粒子束投递系统140运动至目标放射区域，确保目标放射区域的准确性，保证治疗过程的可靠性。
当配准结果目标放射区域的配准率没有达到配准率阈值时，需要重新执行成像配准，或者重新拍摄当前影像信息，进行配准。
在一些实施例中，步骤270、控制粒子束投递系统140根据扫描路径信息投放粒子束供应系统130生成并分配的目标粒子束流，包括：
在目标粒子束流的剂量小于剂量阈值的情况下，控制粒子束投递系统140根据扫描路径信息投放目标粒子束流。
在该实施例中，粒子束投递系统140对目标粒子束流的剂量信息进行验证，如果剂量超过安全的剂量阈值，则会产生高剂量报警，并不会进行束流投递。
在目标粒子束流的剂量小于剂量阈值的情况下，控制粒子束投递系统140根据扫描路径信息投放目标粒子束流，保证目标粒子束流投放的安全性。
在一些实施例中，粒子放射治疗系统100的控制方法还包括：
接收安全系统150输出的放射室系统的碰撞报警信息；
控制放射室系统进入碰撞处理模式，运动系统170的设备在碰撞处理模式下以安全速度进行点动运行。
在该实施例中，治疗控制系统110和安全系统150具有防碰撞功能，当安全系统150检测到放射室系统发生碰撞时，输出对应的碰撞报警信息，控制发生碰撞的放射室系统进入碰撞处理模式，碰撞处理模式下，运动系统170的设备以预先配置的安全速度进行点动运行，防止碰撞事故进一步加剧，提高系统安全性。
需要说明的是，在下列条件之一时不允许运动系统170的设备运动：用户未登录；安全系统150联锁报警；放射室内束流正在排队或正在进行照射；放射室内的照射处于暂停状态；粒子束投递系统140处于治疗模式。
下面介绍一个具体的实施例。
如图4所示，步骤410、在用户登录治疗控制系统110时，进行身份验证授权，该用户为可以操作治疗控制系统110，控制工作流程的医师(即第一用户)。
在该步骤中，进行身份验证授权，包括对医师进行身份验证授权，以及对放射室内患者进行身份验证。
步骤420、影像区清场后，执行影像拍照。
在执行影像拍照前，安装光学追踪系统和束流调制设备，并选择照射野，医师和患者进入放射室，医师操作控制治疗床运动到上床位并验证患者是否与治疗控制系统110上的患者信息一致。
如果相一致，患者上床并固定体位，医师控制治疗床运动到激光标记的等中心位，完成患者粗摆位。对影像区进行清场，影像系统160执行影像拍照和图像配准。
步骤430、特定用户权限对影像系统160上传的配准结果进行确认授权。
配准完成后，像系统会把配准结果发送给治疗控制系统110，此时需要相应特定用户权限的医师对该配准结果进行确认，如该配准结果低于配置文件中配置的限值，则确认失败，不能继续流程，需重新执行影像拍照和图像配准。
步骤440、施加配准结果，将治疗床移动到治疗位。
当前会话中，只有施加了配准结果，治疗控制系统110才允许用户将治疗床移动到治疗位；当配准结果低于配置文件中配置的配准率阈值时，用户无法在治疗控制系统110上进行确认，并且当前工作流不能继续，如果要继续，则需要重新执行成像配准。
步骤450、对患者信息和治疗计划进行确认。
步骤460、放射室清场后，执行束流投递。
粒子束投递系统140会验证来自治疗控制系统110的剂量信息，如果剂量超过安全的剂量阈值，则会产生高剂量报警，并不会进行束流投递。
治疗控制系统110和安全系统150具有防碰撞功能，当安全系统150检测到碰撞，向治疗控制系统110发送碰撞信息，治疗控制系统110会显示警告并进入碰撞处理模式，碰撞处理模式下运动系统170的设备仅允许以预先配置的安全速度进行点动运行。
在下列条件之一时治疗控制系统110不允许运动系统170的设备运动：用户未登录；安全系统150联锁报警；放射室内束流正在排队或正在进行照射；放射室内的照射处于暂停状态；粒子束投递系统140处于治疗模式。
在一些实施例中，如图5所示，本发明实施例还提供一种电子设备500，包括处理器501、存储器502及存储在存储器502上并可在处理器501上运行的计算机程序，该程序被处理器501执行时实现上述粒子放射治疗系统100的控制方法实施例的各个过程，且能达到相同的技术效果，为避免重复，这里不再赘述。
本发明实施例还提供一种非暂态计算机可读存储介质，该非暂态计算机可读存储介质上存储有计算机程序，该计算机程序被处理器执行时实现上述粒子放射治疗系统100的控制方法实施例的各个过程，且能达到相同的技术效果，为避免重复，这里不再赘述。
其中，所述处理器为上述实施例中所述的电子设备中的处理器。所述可读存储介质，包括计算机可读存储介质，如计算机只读存储器ROM、随机存取存储器RAM、磁碟或者光盘等。
本发明实施例还提供一种计算机程序产品，包括计算机程序，该计算机程序被处理器执行时实现上述粒子放射治疗系统100的控制方法。
其中，所述处理器为上述实施例中所述的电子设备中的处理器。所述可读存储介质，包括计算机可读存储介质，如计算机只读存储器ROM、随机存取存储器RAM、磁碟或者光盘等。
需要说明的是，在本文中，术语“包括”、“包含”或者其任何其他变体意在涵盖非排他性的包含，从而使得包括一系列要素的过程、方法、物品或者装置不仅包括那些要素，而且还包括没有明确列出的其他要素，或者是还包括为这种过程、方法、物品或者装置所固有的要素。在没有更多限制的情况下，由语句“包括一个……”限定的要素，并不排除在包括该要素的过程、方法、物品或者装置中还存在另外的相同要素。此外，需要指出的是，本发明实施方式中的方法和装置的范围不限按示出或讨论的顺序来执行功能，还可包括根据所涉及的功能按基本同时的方式或按相反的顺序来执行功能，例如，可以按不同于所描述的次序来执行所描述的方法，并且还可以添加、省去、或组合各种步骤。另外，参照某些示例所描述的特征可在其他示例中被组合。
通过以上的实施方式的描述，本领域的技术人员可以清楚地了解到上述实施例方法可借助软件加必需的通用硬件平台的方式来实现，当然也可以通过硬件，但很多情况下前者是更佳的实施方式。基于这样的理解，本发明的技术方案本质上或者说对现有技术做出贡献的部分可以以计算机软件产品的形式体现出来，该计算机软件产品存储在一个存储介质(如ROM/RAM、磁碟、光盘)中，包括若干指令用以使得一台终端(可以是手机，计算机，服务器，或者网络设备等)执行本发明各个实施例所述的方法。
上面结合附图对本发明的实施例进行了描述，但是本发明并不局限于上述的具体实施方式，上述的具体实施方式仅仅是示意性的，而不是限制性的，本领域的普通技术人员在本发明的启示下，在不脱离本发明宗旨和权利要求所保护的范围情况下，还可做出很多形式，均属于本发明的保护之内。
在本说明书的描述中，参考术语“一个实施例”、“一些实施例”、“示意性实施例”、“示例”、“具体示例”、或“一些示例”等的描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本发明的至少一个实施例或示例中。在本说明书中，对 上述术语的示意性表述不一定指的是相同的实施例或示例。而且，描述的具体特征、结构、材料或者特点可以在任何的一个或多个实施例或示例中以合适的方式结合。
尽管已经示出和描述了本发明的实施例，本领域的普通技术人员可以理解：在不脱离本发明的原理和宗旨的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由权利要求及其等同物限定。

Claims (12)

  1. 一种粒子放射治疗系统，其特征在于，包括：
    至少一个放射室系统，所述放射室系统包括影像系统、运动系统、粒子束投递系统和安全系统；
    治疗控制系统，所述治疗控制系统分别与所述影像系统、所述运动系统、所述粒子束投递系统和所述安全系统连接，所述安全系统用于输出设备联锁信号和设备报警信号；
    粒子束供应系统，所述粒子束供应系统与所述治疗控制系统连接；
    所述治疗控制系统包括用户交互组件，所述用户交互组件用于接收第一用户输入的第二用户的放射治疗信息；
    所述影像系统用于采集所述第二用户身体部位的当前影像信息，所述当前影像信息用于与所述放射治疗信息的用户影像信息进行配准，确定所述第二用户的目标放射区域；
    所述运动系统用于驱动所述粒子束投递系统运动至所述目标放射区域；
    所述治疗控制系统用于基于所述放射治疗信息，向所述粒子束供应系统发送束流调度请求信息；
    所述粒子束供应系统用于基于所述束流调度请求信息，生成并分配目标粒子束流至所述粒子束投递系统；
    所述治疗控制系统用于基于所述放射治疗信息，确定所述目标放射区域的扫描路径信息，控制所述粒子束投递系统根据所述扫描路径信息投放所述目标粒子束流。
  2. 根据权利要求1所述的粒子放射治疗系统，其特征在于，所述治疗控制系统包括：
    至少一个放射室组件，所述放射室组件与所述放射室系统一一对应，所述放射室组件用于控制所述放射室组件对应的所述放射室系统内的工作流程；
    束流调度组件，所述束流调度组件与所述粒子束供应系统连接；
    成像配准组件、运动组件和剂量投递组件，所述成像配准组件与所述影像系统连接，所述运动组件与所述运动系统连接，所述剂量投递组件与所述粒子束投递系统连接。
  3. 根据权利要求1所述的粒子放射治疗系统，其特征在于，所述治疗控制系统包括监控组件，所述监控组件与所述安全系统连接，所述监控组件用于监控所述治疗控制系统的组件状态和所述放射室系统的传感器状态，以及处理所述安全系统输出的所述设备联锁信号和所述设备报警信号。
  4. 根据权利要求1-3任一项所述的粒子放射治疗系统，其特征在于，所述运动系统包 括摆位设备和旋转机架，所述旋转机架安装于所述摆位设备，所述粒子束投递系统包括束流调制设备，所述束流调制设备安装于所述旋转机架，所述旋转机架用于控制所述束流调制设备投放粒子束流的束流方向，所述摆位设备用于驱动所述束流调制设备运动至所述目标放射区域。
  5. 根据权利要求1-3任一项所述的粒子放射治疗系统，其特征在于，所述治疗控制系统包括用户验证组件，所述用户验证组件用于对所述第一用户或所述第二用户的用户身份进行验证。
  6. 一种基于权利要求1-5任一项所述粒子放射治疗系统的控制方法，其特征在于，包括：
    获取第二用户的放射治疗信息；
    控制影像系统采集所述第二用户身体部位的当前影像信息；
    基于所述当前影像信息和所述放射治疗信息的用户影像信息进行配准，确定所述第二用户的目标放射区域；
    控制运动系统驱动粒子束投递系统运动至所述目标放射区域；
    基于所述放射治疗信息，向所述粒子束供应系统发送束流调度请求信息；
    基于所述放射治疗信息，确定所述目标放射区域的扫描路径信息；
    控制粒子束投递系统根据所述扫描路径信息投放所述粒子束供应系统生成并分配的目标粒子束流。
  7. 根据权利要求6所述的粒子放射治疗系统的控制方法，其特征在于，所述获取第二用户的放射治疗信息，包括：
    在第一用户的身份验证通过的情况下，获取所述第二用户的放射治疗信息；
    所述控制影像系统采集所述第二用户身体部位的当前影像信息，包括：
    在所述第二用户的身份验证通过，且所述影像系统的拍摄区域清场的情况下，控制所述影像系统采集所述当前影像信息；
    所述控制粒子束投递系统根据所述扫描路径信息投放所述粒子束供应系统生成并分配的目标粒子束流，包括：
    在所述放射室系统清场，且接收到所述第一用户输入的放射确认信息的情况下，控制所述粒子束投递系统根据所述扫描路径信息投放所述目标粒子束流。
  8. 根据权利要求6所述的粒子放射治疗系统的控制方法，其特征在于，所述控制运动系统驱动粒子束投递系统运动至所述目标放射区域，包括：
    在所述目标放射区域的配准率大于配准率阈值的情况下，控制所述运动系统驱动所述粒子束投递系统运动至所述目标放射区域。
  9. 根据权利要求6所述的粒子放射治疗系统的控制方法，其特征在于，所述控制粒子束投递系统根据所述扫描路径信息投放所述粒子束供应系统生成并分配的目标粒子束流，包括：
    在所述目标粒子束流的剂量小于剂量阈值的情况下，控制所述粒子束投递系统根据所述扫描路径信息投放所述目标粒子束流。
  10. 根据权利要求6-9任一项所述的粒子放射治疗系统的控制方法，其特征在于，所述方法还包括：
    接收安全系统输出的所述放射室系统的碰撞报警信息；
    控制所述放射室系统进入碰撞处理模式，所述运动系统的设备在所述碰撞处理模式下以安全速度进行点动运行。
  11. 一种电子设备，其特征在于，包括存储器、处理器及存储在所述存储器上并可在所述处理器上运行的计算机程序，所述处理器执行所述计算机程序时实现如权利要求6-10任一项所述的粒子放射治疗系统的控制方法。
  12. 一种非暂态计算机可读存储介质，其特征在于，存储有计算机程序，所述计算机程序被处理器执行时实现如权利要求6-10任一项所述的粒子放射治疗系统的控制方法。
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