WO2024076487A1 - Procédé et système de fourniture de commande non invasive d'un écoulement de fluide dans des tubes élastomères - Google Patents

Procédé et système de fourniture de commande non invasive d'un écoulement de fluide dans des tubes élastomères Download PDF

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Publication number
WO2024076487A1
WO2024076487A1 PCT/US2023/033920 US2023033920W WO2024076487A1 WO 2024076487 A1 WO2024076487 A1 WO 2024076487A1 US 2023033920 W US2023033920 W US 2023033920W WO 2024076487 A1 WO2024076487 A1 WO 2024076487A1
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WO
WIPO (PCT)
Prior art keywords
motor
control
fluid flow
plungers
fluid
Prior art date
Application number
PCT/US2023/033920
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English (en)
Inventor
Farrukh USMAN
Michael Wollowitz
Ahmed ALAM ANSARI
Abdul QADEER
Original Assignee
Usman Farrukh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usman Farrukh filed Critical Usman Farrukh
Publication of WO2024076487A1 publication Critical patent/WO2024076487A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877—Adjusting flow; Devices for setting a flow rate
    • A61M5/16881—Regulating valves

Definitions

  • the present disclosure is directed to a Non-invasive Flow Control in Elastomeric Tubes with several applications spanning the medical, food, and pharmaceutical industries, among others.
  • Control of flow rate and start-stop operation of fluids is necessary for several applications spanning the medical, food, and pharmaceutical industries, among others.
  • the fluid (which may be gas or liquid) must remain isolated from the environment to prevent contamination either of the fluid by the environment or the surrounding environment by the fluid.
  • a disposable “set” may be used to transfer fluid from e.g., a sterile container to a patient. The set is presterilized and disposed of after a single use, thereby minimizing the risk of contamination.
  • any method to control or start-stop fluid flow where external components do not directly contact the fluid is termed non-invasive.
  • methods in which external components touch or otherwise influence fluid flow invasively are termed invasive methods.
  • invasive methods For example, a simple water faucet controls water flow invasively since valve components are in direct contact with water.
  • Such an invasive method is common in various industrial applications.
  • invasive methods are unacceptable in many applications such as the medical devices industry.
  • the fluid flow must be automated and is part of a controlled process. Therefore, the method, invasive or non-invasive, will necessitate the use of an actuator that limits or eliminates the manual operation of the fluid flow components.
  • One non-invasive fluid flow control approach is to place components outside the fluid path and interact with the fluid channel through the flexible periphery of the fluid path.
  • One general implementation of this approach operates by pinching an elastomeric, fluid conveying tube against a rigid counter surface using a wedge-shaped profile (here referred to as a “plunger”). When the tube is pinched with sufficient force, the fluid channel is completely pressed close, fluid flow is restricted. When the pinching force on the tube is removed by retracting the plunger, the elastomer tube regains some or all of its original undeformed form, and fluid flow is restored partially or fully.
  • the present invention employs an actuated assembly that operates two plungers that can control fluid flow in elastomer tubes in a non-invasive, normally closed, and antagonistic manner.
  • the invention can also be easily automated and interfaced with a control system, allowing the invention to be a part of an automated production process or a computer- controlled machine.
  • Fluid flow control valve and transfer set US4821996, Baxter the invention in this prior art claims the methods and devices used in connection with carrying out peritoneal dialysis. More particularly, the invention pertains to a valve system, fluid transfer set, and method that facilitates executing the steps of a drain and fill cycle associated with continuous ambulatory peritoneal dialysis.
  • the present invention is related to general applications of fluid flow control through elastomeric tubes including those of Continuous Ambulatory Peritoneal Dialysis (CAPD) and Automated Peritoneal Dialysis (APD).
  • CAPD Continuous Ambulatory Peritoneal Dialysis
  • APIPD Automated Peritoneal Dialysis
  • the present invention is controlled through automated means (actuator-driven) whereas the prior art would manually control the fluid flow. Furthermore, the present invention is fail-safe in case of power failure, whereas the prior art requires manual intervention to start, stop or control fluid flow.
  • the present invention is intended to be used with sets of single continuous elastomer tubes than the prior art that can be used with three tubes that connect to the invention’s outlets.
  • the present invention is a completely non-invasive fluid flow control method that is non-disposable, but the prior art is invasive in its working which necessitates that this invention is disposed of after use in sterile applications. 2.
  • Flow control device for peritoneal dialysis in one embodiment includes (i) the first cap including a first medical fluid line connection and a second medical fluid line connection; (ii) a gasket mated with the first cap where the gasket defines a first aperture in fluid communication with a first port and a second aperture in fluid communication with a second port; and (iii) a second cap including a third medical fluid line connection where the second cap is sealed rotatably to the gasket.
  • the above invention serves the same purpose as ours which is “controlling fluid”. The difference is that they are controlling fluid flow invasively whereas the present invention is non-invasive. For sterile applications, there would be a necessity to use a new copy of this invention whereas the present invention is non-disposable even for sterile applications.
  • This invention makes use of rotary components to control fluid flow whereas the present invention makes use of linear plungers which interact directly with elastomer tubes without contact with the fluid.
  • the present invention can be used in general fluid flow applications including but not limited to peritoneal dialysis whereas the prior art is specifically intended for peritoneal dialysis.
  • a first example includes a system for a non-invasive Flow Control in Elastomeric Tubes, as shown in FIG 1, comprising a spring-based assembly 18 of two plungers 15, 22, an actuator motor 11, and Elastomer tubes 37.
  • the motor is available in various possible forms that are back driven and can maintain a position when powered.
  • the plungers are spring-loaded in a normally closed configuration and are partially actuated in the opening direction through a mechanical linkage.
  • the plunger is antagonistic in action, such that only one plunger can open at once.
  • the spring action and the design of the mechanical linkage allow both plungers to be in the closed state simultaneously.
  • a second example includes the method of example 1 in which the mechanical linkage is a four-bar linkage.
  • a third example includes the method of example 1 in which the mechanical linkage is allowed to operate at or near the toggle position such that the spring force on the actuator is near zero. This allows low power operation of the actuator which may be operated at lower power settings or the power to the actuator may be completely cut off.
  • a fourth example includes the method of example 1, in which the mechanism is restricted to operate near the toggle point such that the invention is fail-safe by design. This means that when the actuator is powered and opening one of the plungers against the spring, the spring force exerts sufficient force or torque on the actuator to allow the plunger to return to the closed state in case of power failure to the actuator,
  • a fifth example includes the method of examples 1, 2, 3 and 4, where the plungers are wedged-shaped profiles, without any emphasis on specific profile designs, which push against elastomer tubes perpendicularly to the tube axis with sufficient force to close the walls of the tubes and restrict fluid flow.
  • the plunger 22 may be integral to the plunger shaft 15 or may be separately mounted on the plunger shaft by means such as interference fit, mechanical fastening, or adhesives, among other methods.
  • a sixth example includes the methods of the previous examples, where the invention uses a closed loop control system and a sensor to track the position and open- closed state of the system.
  • FIG 1 is an elevation view of the present invention.
  • FIG 2A and 2B show an isometric view of the invention with four-bar linkage, two plungers in the closed position, springs, and a driving motor.
  • FIG 3 A and 3B a different isometric, plan, and elevation views of the invention with four-bar linkage and springs with the top plunger in the open position.
  • FIG 4 shows the front elevation view of the invention with a four-bar linkage that operates away from the toggle position of the linkage.
  • FIG 5A and 5B show the front elevation views of the invention with a four-bar linkage that operates near or at the toggle position of the linkage.
  • FIG 6A-6H shows various front elevation and isometric views of the invention, showing one possible method of mounting the elastomeric tubes on a pivoting mounting assembly. One sub-figure shows the sliding assembly being actuated by an actuator.
  • FIG 7A-7H show various front elevation and isometric views of the invention, showing one possible method of mounting the elastomeric tubes on a static mounting assembly.
  • FIG 8A and 8B show the front elevation, sectional, and isometric views of the invention in use with a cassette. These Figures show the fluid pathways in detail.
  • FIG 9A and 9B are a front elevation and isometric view of a symmetric rocker.
  • satisfying a threshold may, depending on the context, refer to a value being greater than the threshold, greater than or equal to the threshold, less than the threshold, less than or equal to the threshold, equal to the threshold, and/or the like, depending on the context.
  • the articles “a” and “an” are intended to include one or more items and may be used interchangeably with “one or more.”
  • the article “the” is intended to include one or more items referenced in connection with the article “the” and may be used interchangeably with “the one or more.”
  • the term “set” is intended to include one or more items (e.g., related items, unrelated items, a combination of related and unrelated items, and/or the like), and may be used interchangeably with “one or more.” Where only one item is intended, the phrase “only one” or similar language is used.
  • the terms “has,” “have,” “having,” or the like are intended to be open-ended terms.
  • the present disclosure is directed to a Non-invasive Flow Control in Elastomeric Tubes with several applications spanning the medical, food, and pharmaceutical industries, among others.
  • the components included in the system and their functions are delineated below:
  • the Rotary Motor 11 is an electrical actuator in some of the embodiments.
  • the Motor 11 is mounted on a Plate 1 and this plate provides a means for mounting the actuator.
  • a crankshaft 2 is a metallic or otherwise shaft that mounts the Crank 3.
  • the Crank 3 is the driving link in the mechanical linkage. It may be mounted directly onto the actuator or through a linkage or gear transmission.
  • the Crank Pin 4 is the pin on the crank 3 that interacts with the slot in the rocker in one embodiment.
  • the rocker 9 is a part of the mechanical linkage in one embodiment that pulls the plunger shaft 15 against the springs through the plunger pin 16.
  • Rocker Shaft 10 is a metallic or otherwise shaft that provides a pivot for the rocker.
  • the Plunger Plate 12 simply provides a mechanical structure for the linear bearings for the plunger shaft 15.
  • the Plunger Shaft 15 forms a part of the plunger 22 in some embodiments.
  • the Plunger Pin 16 is a pin on the plunger that interacts with the rocker.
  • Spring 18 is a helical compression spring.
  • a plunger 22 is a wedge-shaped profile that interacts with the elastomeric tubes.
  • the retaining Ring 27 is a common mechanical fastening element.
  • Mounting Assembly 34, 35, 36, 38 is a structure for mounting the elastomeric tubes in some of the embodiments.
  • the lead screw 35 is a common mechanical transmission element.
  • the organizer tray/slider 36 is a part of the mechanical structure of the mounting assembly 34.
  • An Elastomeric Tube or elastomer tube 37 is a flexible tube intended for fluid flow.
  • Hinge/Pivot 38 is simply a pivot for a rotating body.
  • Mounting Assembly Actuator 40 is an actuator in the mounting assembly in some of the embodiments.
  • Fluid Inlet Path 41 is a path for the fluid to flow.
  • Fluid Outlet Path 42 is a path for the fluid to flow.
  • Countersurface Washer 43 is an elastomeric washer that deforms to form a sealable periphery.
  • the diaphragm 44 is a flexible membrane.
  • a cassette 45 is a body in some of the embodiments with several fluid pathways that can be opened or closed as needed.
  • Virtual Crank Link or Crank Axis 50 is the line running along the Crank 3 through the center of the crank pin 4 and the crankshaft axis.
  • the virtual Rocker and Slider Link (Rocker Axis) 51 is the line joining the center of the plunger pin 16 and the crank pin 4 on the rocker 9 through the rocker.
  • the translating Axis for the Top Plunger Shaft 60 is the center axis of the top plunger shaft 15.
  • FIG. 1 shows the front elevation view of a spring-based assembly 18 of two plungers 15, 22 that are used to control fluid flow in two separate elastomer tubes through a four-bar linkage.
  • FIG. 2A illustrates the isometric view of the identical apparatus as Fig 1, which shows a mechanical linkage where the rocker 9 has two extended arms at specific angles about the rocker mid-plane.
  • the crank 3 is driven by a rotary motor (explained below) and in turn, moves the pin 4 inside the rocker slot thereby rotating the rocker in a certain direction.
  • the rocker’s arm pushes against a pin 16 on the plunger to open it against the spring 18.
  • FIG. 2B illustrates the isometric view of the identical apparatus as Fig 1 and 2A, which shows the rotary motor 11 connected to the crankshaft 2 which drives the crank 3.
  • FIG. 3 A shows the front elevation view of an identical apparatus as Fig 1, with the top plunger 15,22 in the open state. The bottom plunger remains unaffected and in a closed state.
  • FIG. 3B shows the isometric view of an identical apparatus as Fig 2A, with the top plunger 15,22 in the open state.
  • FIG. 4 shows the front elevation view of the four-bar linkage.
  • the spring force should exert sufficient torque through the mechanism at the crank 3 to overcome the motor cogging torque. This can be set by changing the link dimensions of the four-bar mechanism and/or changing the spring stiffness. In such an embodiment, the four-bar mechanism must operate away from the toggle position This may be achieved by mechanically limiting the rotational travel of the crank or the rocker.
  • the figure shows the non-perpendicular angle between the crank axis 50 and the rocker axis 51 which results in a non-zero torque at the crank 3 due to spring force.
  • FIG. 5A shows the front elevation view of the invention with modified geometries of the crank 3 and the rocker 9 which allow the linkage to be positioned at a perpendicular or near-perpendicular angle between the crank axis 50 and the rocker axis 51 At this toggle position, the force of the springs will result in a zero or near-zero torque at the crank 3.
  • the rotary motor may be switched off or operated at reduced torque at this angle to save power and reduce heat generation. In such an embodiment, the invention no longer remains failsafe upon power failure. Such an embodiment may be useful in applications when fail-safety is not required, and improved energy efficiency is desirable.
  • FIG. 5B shows the elevation view of the embodiment with a greater focus on the four-bar linkage.
  • FIG. 6A shows the invention consisting of a mounting assembly 34, 35, 36, 38 that allows the user to easily place the tubes 37 in front of the plunging mechanism.
  • the tubes can be organized using an organizer tray 36 which can then be placed inside the mounting assembly.
  • the sliding mechanism 35, 36 in the mounting assembly is a leadscrew & threaded hole linear-motion combination that can then gradually load the tubes against the closed plungers. In such a case, both tubes 37 will be in a closed state when loaded.
  • FIG. 6B to FIG. 6F shows different elevation and isometric views of the apparatus.
  • FIG. 6G shows the elevation view of another embodiment similar to the one shown in FIG 6A.
  • the sliding mechanism can be actuated using a motor 40, hydraulic actuator, or pneumatic actuator, amongst others.
  • FIG. 6H shows the isometric view of the embodiment presented in FIG 6G.
  • FIG. 7A shows the isometric view of an embodiment consisting of a simple rigid counter surface 34 that may be used with the plunging mechanism.
  • one of the plungers 22 may be retracted to allow the initial placement of the first tube easily.
  • the second plunger may then be retracted to allow initial placement of the second tube easily.
  • FIG. 7B shows the front elevation view of the embodiment presented in FIG 7A.
  • FIG. 7C shows the front elevation view of the embodiment presented in Fig 7A, with the top plunger in the open state.
  • FIG. 7D shows the front elevation view of the embodiment presented in Fig 7A, with the top plunger in the open state. The tube 37 is then placed when the top plunger is retracted.
  • FIG. 7E shows the front elevation view of the embodiment presented in Fig 7A, with the top plunger in the closed state and pushing against the top tube 37.
  • FIG. 7F shows the front elevation view of the embodiment presented in Fig 7A, with the bottom plunger in the open state.
  • FIG. 7G shows the front elevation view of the embodiment presented in Fig 7A, with the bottom plunger in the open state. The tube 37 is then placed when the bottom plunger is retracted.
  • FIG. 7H shows the front elevation view of the embodiment presented in Fig 7A, with the bottom plunger in the closed state and pushing against the bottom tube 37.
  • FIG. 8A shows the front elevation and side sectional views of the cassette 45 and internal fluid pathways.
  • the fluid inlet 41 is connected to the fluid outlet 42. This connection can be obstructed by pushing the diaphragm 44 against the countersurface washer 43.
  • FIG. 8B shows the side elevation and isometric views of the cassette 45 with the plunging mechanism.
  • the plunger 15 pushes against the diaphragm 44 to obstruct or clear the pathway between the fluid inlet 41 and the fluid outlet 42 as shown in Fig 8 A.
  • FIG. 9A shows the front elevation view of a symmetric rocker.
  • FIG. 9B shows the isometric view of a symmetric rocker.
  • the invention employs a mechanical linkage. All embodiments covered in this document employ four-bar linkages, but other linkages may be used with identical results.
  • the rocker 9 has two extended arms at specific angles about the rocker mid-plane. The rocker is depicted separately in FIG 9A and 9B. These angles may be symmetric about the rocker mid-plane or may differ, depending on specific implementations.
  • the crank 3 is driven by a rotary motor (explained below) and in turn, moves the pin 4 inside the rocker slot thereby rotating the rocker in a certain direction.
  • the rocker arm then pushes against a pin 16 on the plunger.
  • the plunger then moves linearly in a set of bushes or linear bearings (the supporting bearing arrangement is not depicted herein).
  • the invention is fail-safe.
  • the springs 18 push the plunger back against tube 37 to the closed state. If one of the plungers was in the open state when the power failure occurred, the spring will push against the plunger which will then push against the rocker's arm through the plunger pin 16. The rocker arm will resultantly restore the crank 3 to the normally closed/neutral position against the motor cogging torque.
  • the spring force should exert sufficient torque through the mechanism at the crank to overcome the motor-cogging torque. This can be set by changing the link dimensions of the four-bar mechanism and/or changing the spring stiffness. The four-bar mechanism must operate away from the toggle position in such an embodiment. This may be achieved by mechanically limiting the rotational travel of the crank or the rocker.
  • the invention is self-locking. If the crank axis 50 is allowed to move to a position that is perpendicular to the rocker axis 51, the four-bar mechanism will be at the toggle position, such that the output force of the springs will result in zero torque at the crank 3.
  • the motor may be switched off or operated at reduced torque at this angle to save power and reduce heat generation.
  • the invention no longer remains fail-safe upon power failure. Such an embodiment may be useful in applications when fail-safety is not required and improved energy efficiency is desirable.
  • a motor (as shown in FIG 2B, 11) is used to drive the crank 3.
  • the motor is not depicted in other illustrations for clarity; the mounting means for the motor are also not illustrated.
  • the motor may be an AC or DC motor, including a servo motor or stepper motor.
  • the motor may drive the crank directly or through internal or external gearing. There is no preference for motor type although certain applications may prefer particular motor types.
  • the torque at the motor shaft in case of power failure, must overcome any residual torque of the motor or associated drive components so that the crank is restored to its neutral position, as described before. This characteristic of the motor is often referred to as “back-drive-ability” and is mostly a subjective parameter.
  • the residual torque is also referred to as “open-circuit torque”, “cogging torque” or “detent torque” in the case of stepper motors, and is the torque required to rotate the motor shaft when it is unpowered.
  • open-circuit torque such as “cogging torque” or “detent torque”
  • detent torque such as the torque required to rotate the motor shaft when it is unpowered.
  • embodiments that are not fail-safe may or may not involve back-driveable motors since the four-bar toggle positioning makes the mechanism non-fail-safe (self-locking) regardless of the degree of back-drive-ability of the motor.
  • the motor itself may be run in open-loop or closed-loop positional control.
  • a rotational position sensor such as a non-contact hall effect sensor, may be used to obtain position feedback from the angular position of the motor shaft, crankshaft 2, or rocker shaft 10. This feedback may then be used for motor positional control as well as to obtain information about which valve is opened or closed.
  • An absolute position sensor is preferred to set up a consistent zero reference position at the neutral position of the crank even when power to the invention is turned off.
  • limit switches may be used to detect the linear limits of the two plunger shafts 15 to control the rotational limits of the motor. These limit switches may be of the contact or non-contact type (such as photo interrupters) without any preference, although certain applications may prefer particular types.
  • the invention may be used in two broad ways: 1) for start-stop control of fluid flow, and 2) to control the rate of fluid flow in an open-loop or closed-loop system.
  • the invention is also partially actuator-independent such that the plungers can be moved in the open direction without any actuator influence.
  • This invention allows tubes of different sizes (ID, OD, and wall thickness) and hardness to be utilized.
  • the springs 18 can be sized to control the closing force on the tube in the closed position.
  • the linear distance required to allow fluid flow can be controlled by designing the link lengths accordingly.
  • the plunger’s total stroke depends upon the four-bar mechanism's linkage lengths. By applying trigonometric relationships, a relationship can be developed that relates the link lengths, the driving crank angle, and the stroke. Link lengths also dictate the torque required at the crank for compressing the spring.
  • the invention consists of a mounting assembly 34, 35, 36, 38 that allows the user to easily place tubes 37 in front of the plunging mechanism.
  • the tubes can be organized using an organizer tray 36 which can then be placed inside the mounting assembly.
  • the sliding mechanism 35, 36 in the mounting assembly is a lead screw & threaded hole linear-motion combination that can then gradually load the tubes against the closed plungers. In such a case, both tubes 37 will be in a closed state when loaded.
  • the sliding mechanism can be actuated using a motor, hydraulic actuator, or pneumatic actuator, amongst others (40, FIG 6C, 6D).
  • a simple rigid counter surface 34 may be used with the plunging mechanism.
  • one of the plungers 22 may be retracted to allow the initial placement of the first tube easily.
  • the second plunger may then be retracted to allow initial placement of the second tube easily.
  • the invention may be used in conjunction with a “cassette” (45, FIG 8A, 8B) consisting of an elastomeric sheet or diaphragm 44.
  • the cassette is supported rigidly by a specific arrangement.
  • Such a diaphragm may be pushed against a countersurface washer 43 to open or block a 3 -dimensional fluid path to allow or restrict fluid flow respectively.
  • the fluid inlet path 41 is normally open to the fluid outlet 42 when the diaphragm is in its relaxed state.
  • the diaphragm 44 is pushed inwards (towards 43) by the plungers 15 in the normally closed configuration described in earlier embodiments, the fluid pathway is blocked, and flow is restricted.
  • the diaphragm When one of the plungers is retracted, the diaphragm is restored to its relaxed position, and/or positive pressure from the fluid inlet forces the fluid pathway from 41 to 42 to open, hence, fluid flow is restored.
  • the “cassette” may be of several different designs depending on required fluid pathways. For example, in FIG 7A, 7B, all four outlets are connected to a common inlet, but this may differ in different applications. The number of inlets and outlets may also differ.
  • the design elements of the invention also permit one valve to be fail-safe by limiting the driving angle on that side, while the other valve is allowed to go into a selflocking state.
  • Such a device may be useful in applications using two elastomeric tubes in which flow in one tube needs to be fail-safe, without any restrictions on fluid flow in the other tube.
  • the driving angle will be asymmetrical and will allow zero or reduced energy expenditure when keeping the non-fail-safe valve open.
  • All embodiments are very useful in applications where antagonistic fluid flow in a pair of fluid pathways is required, i.e., when fluid flow is required in one out of two fluid pathways only and the other tube must necessarily restrict fluid flow.
  • the invention can be multiplied to form plunging assemblies in multiples of 2, i.e., 2, 4, 6, 8, and so on. However, the working of the individual plunging assemblies will remain the same. Such an embodiment is useful in applications where flow in multiple tubes needs to be controlled such as automated peritoneal dialysis machines or pharmaceutical dispensing machines, amongst others.
  • the present invention pertains several benefits as it provides a ready solution for applications where antagonistic fluid flow action is required in two elastomeric tubes. It also allows different configurations to be used with each other to form plunging assemblies in multiples of two. A single motor controlling all the embodiments makes the control easier and more cost-effective. Furthermore, it allows features from several different embodiments to be merged into a single embodiment, e.g., an embodiment may contain features from both fail-safe and self-locking embodiments.

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Fluid Mechanics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un dispositif de commande d'écoulement non invasive qui peut commander l'écoulement de fluide dans des tubes élastomères d'une manière non invasive, normalement fermée et antagoniste. En outre, il comprend une liaison mécanique et un ensemble à ressort de deux pistons qui sont utilisés pour commander l'écoulement de fluide dans deux tubes élastomères séparés. Un seul actionneur est utilisé pour commander les deux pistons. L'invention fonctionne principalement en pinçant des tubes à travers les pistons pour limiter l'écoulement et en se basant sur leurs propriétés élastomères pour permettre un écoulement lorsque les pistons sont suffisamment rétractés. Le mécanisme primaire de l'invention peut être utilisé avec différents mécanismes de montage de tube. Ladite invention peut également être utilisée conjointement avec une cassette dans laquelle les pistons interagissent avec une membrane ou un diaphragme élastomère pour obstruer ou ouvrir un trajet de fluide.
PCT/US2023/033920 2022-10-03 2023-09-28 Procédé et système de fourniture de commande non invasive d'un écoulement de fluide dans des tubes élastomères WO2024076487A1 (fr)

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US202263412570P 2022-10-03 2022-10-03
US63/412,570 2022-10-03

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3543752A (en) * 1964-06-01 1970-12-01 Ruth Leo Hesse Infusion apparatus
US4061142A (en) * 1976-06-16 1977-12-06 Sandoz, Inc. Apparatus for controlling blood flow
US5067359A (en) * 1989-07-19 1991-11-26 Fresenius Ag Apparatus for clamping flexible tubes
US20080304935A1 (en) * 2007-05-01 2008-12-11 Scott Stephen H Robotic exoskeleton for limb movement
US20220023524A1 (en) * 2018-12-07 2022-01-27 W.O.M. World Of Medicine Gmbh Medical flushing pump comprising two suction lines

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3543752A (en) * 1964-06-01 1970-12-01 Ruth Leo Hesse Infusion apparatus
US4061142A (en) * 1976-06-16 1977-12-06 Sandoz, Inc. Apparatus for controlling blood flow
US5067359A (en) * 1989-07-19 1991-11-26 Fresenius Ag Apparatus for clamping flexible tubes
US20080304935A1 (en) * 2007-05-01 2008-12-11 Scott Stephen H Robotic exoskeleton for limb movement
US20220023524A1 (en) * 2018-12-07 2022-01-27 W.O.M. World Of Medicine Gmbh Medical flushing pump comprising two suction lines

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