WO2024012961A1 - Système de désinfection pour patients - Google Patents

Système de désinfection pour patients Download PDF

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Publication number
WO2024012961A1
WO2024012961A1 PCT/EP2023/068622 EP2023068622W WO2024012961A1 WO 2024012961 A1 WO2024012961 A1 WO 2024012961A1 EP 2023068622 W EP2023068622 W EP 2023068622W WO 2024012961 A1 WO2024012961 A1 WO 2024012961A1
Authority
WO
WIPO (PCT)
Prior art keywords
implant system
light
depressions
implant
disinfection
Prior art date
Application number
PCT/EP2023/068622
Other languages
English (en)
Inventor
Yiyu OU
Paul Michael Petersen
Original Assignee
Danmarks Tekniske Universitet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danmarks Tekniske Universitet filed Critical Danmarks Tekniske Universitet
Publication of WO2024012961A1 publication Critical patent/WO2024012961A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0048—Connecting the upper structure to the implant, e.g. bridging bars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A61N5/0603—Apparatus for use inside the body for treatment of body cavities
    • A61N2005/0606—Mouth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0661—Radiation therapy using light characterised by the wavelength of light used ultraviolet

Definitions

  • the invention relates to UV light disinfection systems for disinfection of body tissue of humans or animal.
  • Implants are commonly used in dental surgery for restoring teeth. It is a prosthetic device designed to be implanted into the gingival tissue beneath the periosteal layer and within the bone.
  • WO2019/088939A1 discloses a dental implant healing cap with an integrated LED light source comprising at least one titanium body, at least one screw part for screwing into a female screw part within the implant, at least one main case which has holes, at least one top cover which is screwed onto the body which has a recess in the middle to allow the operator to turn the cover with a multi-sided key, at least one light module (3) for light emission, at least one control unit and at least one battery cell, at least one integrated LED source placed on the lateral sides of the implant facing toward the gingival.
  • an implant system for a patient which comprises
  • an implant body adapted to be implanted in or on a body part of the patient
  • a disinfection portion comprising one or more depressions formed on an exterior surface of the disinfection portion
  • each light unit comprises a light emitter, such as a light emitter, and an electromagnetic coil arranged to power the light emitter when the electromagnetic coil is exposed to a magnetic flux and wherein the plurality of light units are at least partly contained within the one or more depressions.
  • the light units are configured as a single unit containing both the power source, in the form of a coil, and the light emitter.
  • the coil may be configured as windings of an electrical conductor, e.g. planar windings on a substrate, configured as a traditional toroidal coil, or configured in general as 2D or 3D windings on a plane or in a 3D space.
  • an entire light unit can be contained within a depression, while it is also possible that a portion of the light unit may protrude out of the depressions.
  • the lower portion of the light unit such as a substrate thereof can be fixed to the bottom of a depression.
  • the emitted light such as UV light
  • UV light can eradicate bacteria without doing any surgeries.
  • the one or more depressions may be formed as holes or as one or more notches in the exterior surface of the disinfection portion.
  • the implant system is a dental implant system wherein the implant body is adapted to be implanted in the gingival tissue of the patient.
  • the implant system comprises an abutment, wherein the abutment comprises the disinfection portion.
  • the disinfection is most efficient since the oral bacterial infection often take place on the abutment surface or in a region where the abutment surface is in contact with the gum tissue.
  • the dental implant may be configured so that an exterior surface of the abutment faces the gingival tissue when implanted in a patent.
  • the dental implant comprises a dental crown, wherein the abutment is arranged between the implant body and the dental crown.
  • the abutment may comprises a connection portion for attachment of a dental crown.
  • the disinfection portion comprises a bio-compatible protection layer, such as TiO2, covering the depressions.
  • the protection layer protects the light units from body liquids such as the mouth liquids.
  • each of the light units comprises a substrate such as a silicon wafer wherein the electromagnetic coil is arranged on the substrate.
  • the coil may be manufactured as a coil-layer on a substrate such as silicon wafer.
  • the light emitter may be arranged on the substrate are at least electrically connected to the substrate, wherein the substrate comprises an electrical connection connecting the light emitter and the electromagnetic coil.
  • the light unit may have a footprint with a largest dimension being less than 1 mm, preferably less than 500 pm, more preferably less than 200 pm, such as less than 50 pm.
  • the light emitter is configured to emit light in the wavelength range from 200 to 400 nm such as from 280 to 320 nm.
  • a second aspect of the invention relates to a method for manufacturing a disinfection portion for an implant system according to claim 1, the method comprises
  • each light unit comprises a light emitter and an electromagnetic coil arranged to power the light emitter when the electromagnetic coil is exposed to a magnetic flux
  • a third aspect of the invention relates to a disinfection system, comprising
  • a flux generator for generating and transmitting the magnetic flux to the electromagnetic coils of the light units.
  • the implant system may be used for a dental implant, a hearing aid implant, a pacemaker, a bone implant such as a hip implant, a knee implant or an ankle implant.
  • the implant system may be used for maintaining a healthy body tissue, and may be used by the patient, e.g. in the patient's home, although the implant system may also be used by healthcare professionals. Accordingly, the implant system need not necessarily be used for curing a disinfection but may be used for dental hygiene similarly to tooth brushing.
  • the various aspects and embodiments of the invention may be combined and coupled in any way possible within the scope of the invention.
  • Fig. 1 shows a dental implant system
  • Fig. 2 shows a cross-sectional view of a portion of the dental implant system and a detail view of the light unit
  • Fig. 3 shows a method for manufacturing the disinfection portion
  • Fig. 4 a general implant system and flux generator for generating the magnetic flux for generating a current in the coil of the implant system.
  • Fig. 1 shows a dental implant system 100 for a patient.
  • the dental implant system comprises an implant body 102 adapted to be implanted in the gingival tissue 121 of the patient, e.g. by a thread 114 comprised by the implant body and intended to be screwed into the bone part 122.
  • the dental implant system 100 further comprises a disinfection portion 101.
  • the disinfection portion 101 is often termed as an abutment 112 of a dental implant.
  • the disinfection portion 101 comprises one or more depressions 211 formed on an exterior surface 115 of the disinfection portion 101.
  • Each of the depressions 211 has an opening on the exterior surface 212 and extends, e.g. in a radial direction, into the material of the disinfection portion.
  • the depressions may be holes such as cylindrical holes.
  • the one or more depressions are formed as elongate holes extending along at least a fraction of the circumference of the exterior surface 212.
  • a single elongate hole is formed as a notch or a ridge in the exterior surface that circumscribes the annular shape of the disinfection portion 101.
  • each hole may have a diameter equal to or less than 3mm, such as less than 1mm, such as less than 0,5mm, such as less than 0,3mm such as less than 0,1mm.
  • the depth of the holes may be up to 0,5mm, such as up to 1mm or up to 2 to 3 mm.
  • the diameter or a corresponding lateral dimension of the depressions 211 should be larger than the corresponding lateral dimension of the light unit 220 to enable glue to seal the components of the light unit.
  • the depth of the depressions 211 may be chosen to be larger than height of the light units 220 to ensure that the light emitter 113 does not protrude beyond the exterior surface 115 or boundary of the disinfection portion 101.
  • the exterior surface 115 of the abutment 112 will normally face the gingival tissue 121, at least when the gingival tissue 121 is healthy.
  • the one or more depressions may be formed by drilling, laser processing, etching or by other suitable method.
  • the dental implant system 100 further comprises a plurality of light units 220.
  • Each light unit 220 comprises a light emitter 113 such as a LED or a laser diode and an electromagnetic coil 223 electrically connected to the light emitter 113 for powering the light emitter 113.
  • the light emitter 113 may be a UV light emitter.
  • the light emitter is energized by exposing the electromagnetic coil to a magnetic flux such as a magnetic flux with varying flux amplitude and/or flux direction.
  • Fig. 2 shows a cross-sectional view along cross-section A-A, depressions 211 and the light unit 220.
  • each of the light units 220 are completely contained within their associated holes 211. That is, the outermost surface of the light emitter 113, i.e. the surface located radially farthest away from the axial center axis of the abutment 112, is located within the circumference of the exterior surface 115.
  • the light unit 220 extends radially beyond the exterior surface 115 of the abutment 112.
  • the space or a part of the space in the depressions 211 between the outermost surface of the light emitter 113 and the outer circumference of the abutment 112 may be filled with a bio-compatible protection material , such as TiO2, thereby filling the depressions to form a smooth exterior surface 115 over the depressions 211.
  • a part of the light units 220 such as a part of the light emitters may protrude out of the depressions, i.e. beyond the circumference of the exterior surface 115.
  • the electromagnetic coil 223 of each light unit 220 may be arranged on a substrate such as a silicon substrate or wafer.
  • the electromagnetic coil 223 may be formed by printing a conductive metal coil, or by etching or laser processing a deposited metal layer to form a coil on the substrate.
  • the light emitter may be electrically connected to the coil via an electrical connection on the substrate.
  • the coil may be a MEMS coil boned together with the light emitter onto a substrate.
  • the light unit 220 may further comprise an electronic circuit 222 comprising rectifier electronics and a voltage controller or limiter to ensure that the light emitter 113 is supplied with a DC voltage within a maximum voltage limit.
  • the emitted light 225 has a spectral range within a UV range such as within a wavelength range from 200 to 400 nm such as within 280 to 320 nm or within the UVB spectral range.
  • the UVB range is safe for humans and can effectively eradicate biofilms of oral bacteria.
  • the abutment 112 is arranged between the implant body 102 and the dental crown 111.
  • the abutment 112 comprises a connection portion 116 such as a tapered extension upon which the dental crown 111 can be attached e.g. by use of a dental glue.
  • the abutment 112 may further comprise a connection part 117 such as a pin which can be connected to a corresponding hole in the implant body 102, e.g. by gluing or by some mechanical fixation such as threads provided on the pin and the hole in the implant body 102.
  • the abutment part 112 and implant body 102 can be formed as a single piece.
  • One or more of the components of the light unit 220, such as the light emitter 113 and the coil 223 could be arranged on top of each other as illustrated in Fig. 2.
  • the light emitter 113 and the coil 223 could be arranged on the same plane of the substrate 224, e.g. side by side.
  • the light unit 220 has a very small footprint.
  • the largest dimension D of the footprint such as the diameter D of a circular footprint, is less than 1 mm, often less than 500 pm, could be less than 200 pm, such as less than 50 pm.
  • Fig. 3 shows a possible principal method for manufacturing the disinfection portion 101.
  • a body part 401 is provided for manufacturing the disinfection portion.
  • the body part 401 may be made from Titanium.
  • a second step B one or more depressions 211 such as bore holes are made in the exterior surface 115.
  • a plurality of light units 220 are provided.
  • the light units 220 may be been manufactured in a previous separate step. Further in step C, the light units 220 are mounted in the depressions such as by fixing, e.g. by gluing, one light unit 220 in each depression 211 or by fixing a plurality of light units 220 in an elongate depression 211 such as a groove.
  • a layer of bio-compatible material 301 is deposited on the abutment surface, i.e. the exterior surface 115 so that the layer at least covers the outward facing surface of the light units 220 such as the outward facing surface of the light emitters 113.
  • the bio-compatible material 301 may be applied so that the material at least fills the depressions 211 up to the circumference of the exterior surface 115.
  • TiO2 is the natural oxidation layer of Ti material from with the disinfection portion 101 is made, no additional oxidation layer needs to be applied to the exterior surface 115 besides the depressions.
  • Fig. 4 shows a disinfection system 400.
  • the disinfection system 400 comprises the implant system 100 with the implant body 102 adapted to be implanted in or on a body part of the patient and the a disinfection portion 101 comprising one or more depressions 211 and mounted light units 220.
  • the implant system 100 in Fig. 4 may be dental implant system, or an implant system configured as a hearing aid implant, a pacemaker, a bone implant such as a hip, knee or ankle implant.
  • the implant system 100 may be configured for other uses than dental prostheses, but is based on the same general characteristic where the implant system generally comprises an implant body 102 adapted to be implanted in or on a body part of the patient, and a disinfection portion 101 comprising one or more depressions 211 and a plurality of light units arranged at least partly within the one or more depressions.
  • the disinfection system 400 further comprises a flux generator 401 configured for generating and transmitting a magnetic flux to the electromagnetic coils of the light units 220.
  • the flux generator may comprise a power source arranged for generating an alternating electric current.
  • the flux generator further comprises a coil arranged to be powered by the alternating electric current for generating the alternating magnetic flux.
  • the flux generator may further comprise an electronic circuit for controlling e.g. the AC current supplied to the flux generator.
  • the electrically conducting coil of the flux generator 401 may be a separate device which is electrically connectable with the power source and electronic part of the flux generator 401.
  • the coil of the flux generator may be arranged to be placed near the implant system 100, e.g. in the mouth in case of a dental implant system.
  • the disinfection system 400 and the implant system 100 may be used for humans or animals.
  • the patient referred to above may be a human or an animal.

Landscapes

  • Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Abstract

L'invention concerne un système d'implant pour patient, comprenant un corps d'implant adapté pour être implanté dans une partie du corps du patient ou sur celle-ci, une partie de désinfection comprenant une ou plusieurs dépressions formées sur une surface externe de la partie de désinfection, une pluralité d'unités lumineuses, chaque unité lumineuse comprenant un émetteur de lumière et une bobine électromagnétique disposée pour alimenter l'émetteur de lumière lorsque la bobine électromagnétique est exposée à un flux magnétique, et la pluralité d'unités lumineuses étant au moins partiellement contenue dans une ou plusieurs dépressions.
PCT/EP2023/068622 2022-07-12 2023-07-05 Système de désinfection pour patients WO2024012961A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22184292 2022-07-12
EP22184292.5 2022-07-12

Publications (1)

Publication Number Publication Date
WO2024012961A1 true WO2024012961A1 (fr) 2024-01-18

Family

ID=82458399

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2023/068622 WO2024012961A1 (fr) 2022-07-12 2023-07-05 Système de désinfection pour patients

Country Status (1)

Country Link
WO (1) WO2024012961A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180115919A (ko) * 2017-04-14 2018-10-24 주식회사 테코자임 치과용 임플란트 및 어버트먼트
WO2019088939A1 (fr) 2017-10-31 2019-05-09 Benlioglu Musfik Capuchon de cicatrisation d'implant dentaire avec source de lumière à del intégrée pour thérapie photodynamique
CN110917502A (zh) * 2019-11-14 2020-03-27 中山大学 一种可促进牙组织修复的口腔植入式无线供电发光微装置
CN113209491A (zh) * 2021-05-21 2021-08-06 中国科学院半导体研究所 一种光疗装置及其组装方法
WO2021252999A1 (fr) * 2020-06-12 2021-12-16 The Trustees Of The University Of Pennsylvania Système d'implant dentaire intelligent pour soins dentaires ambulatoires

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180115919A (ko) * 2017-04-14 2018-10-24 주식회사 테코자임 치과용 임플란트 및 어버트먼트
WO2019088939A1 (fr) 2017-10-31 2019-05-09 Benlioglu Musfik Capuchon de cicatrisation d'implant dentaire avec source de lumière à del intégrée pour thérapie photodynamique
CN110917502A (zh) * 2019-11-14 2020-03-27 中山大学 一种可促进牙组织修复的口腔植入式无线供电发光微装置
WO2021252999A1 (fr) * 2020-06-12 2021-12-16 The Trustees Of The University Of Pennsylvania Système d'implant dentaire intelligent pour soins dentaires ambulatoires
CN113209491A (zh) * 2021-05-21 2021-08-06 中国科学院半导体研究所 一种光疗装置及其组装方法

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