WO2023284852A1 - 喷雾给药装置和包括该装置的喷雾给药系统 - Google Patents

喷雾给药装置和包括该装置的喷雾给药系统 Download PDF

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Publication number
WO2023284852A1
WO2023284852A1 PCT/CN2022/105940 CN2022105940W WO2023284852A1 WO 2023284852 A1 WO2023284852 A1 WO 2023284852A1 CN 2022105940 W CN2022105940 W CN 2022105940W WO 2023284852 A1 WO2023284852 A1 WO 2023284852A1
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WO
WIPO (PCT)
Prior art keywords
spray
delivery device
drug delivery
nozzle
syringe
Prior art date
Application number
PCT/CN2022/105940
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English (en)
French (fr)
Inventor
丁要武
Original Assignee
丁要武
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 丁要武 filed Critical 丁要武
Priority to EP22841485.0A priority Critical patent/EP4371594A1/en
Priority to JP2024502211A priority patent/JP2024523743A/ja
Publication of WO2023284852A1 publication Critical patent/WO2023284852A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes

Definitions

  • the present application relates to a drug delivery device, especially a drug delivery device that can be used in conjunction with a syringe and deliver medicine to a human body in the form of a spray.
  • Syringes are commonly used medical devices in the medical field, and are used to inject drugs into the human body for disease treatment, vaccine implantation and other operations.
  • a spray drug delivery device used in conjunction with a syringe on the market. After the liquid medicine is sucked into the syringe, the spray drug delivery device can be fitted to the syringe, and then the nozzle of the spray drug delivery device is aimed at the nasal cavity and oral cavity. Or other parts of the human body suitable for drug administration, by pushing the syringe, the drug solution is atomized and delivered to the human body.
  • this spray drug delivery device can evenly deliver the drug solution to the required site, and can reduce the trauma to the human body.
  • the orientation of the spray drug delivery device and the syringe is unreasonable, and the syringe adopts a posture of high front and low rear.
  • the front end of the syringe will be air. What is ejected is also air, and then the liquid medicine is ejected. Therefore, there will be more medicinal liquid remaining in the spray drug delivery device and the syringe, resulting in inaccurate dosage and waste of medicinal liquid.
  • the present invention is made to solve the technical problems in the above-mentioned prior art.
  • the object of the present invention is to provide a spray drug delivery device with improved structure, which avoids the problems of disengagement or leakage between the spray drug delivery device and the syringe when they are socketed.
  • the present invention also improves the structure of the spray drug delivery device to realize sufficient spraying of the drug solution in the device and the syringe.
  • the spray drug delivery device with the improved structure can also realize uniform drug delivery to the two nasal cavities.
  • the spray drug delivery device of the present invention comprises:
  • a sleeve forming a lumen capable of receiving a barrel of a syringe
  • At least one nozzle which is arranged at the front end of the casing and communicates with the inner cavity of the casing
  • the axial direction of the nozzle is angled relative to the axial direction of the sleeve.
  • the axial direction of the nozzle is angled with respect to the axial direction of the cannula, and thus also at the same angle with respect to the axial direction of the syringe inserted in the cannula.
  • the syringe will be in a low-front and high-back posture.
  • the liquid medicine will collect at the front of the syringe, and there will be gas at the back of the liquid medicine.
  • the gas is compressed, and its compression force provides additional power to push the liquid.
  • the compressed gas will play a role in purging the medicinal liquid, thereby pushing away the remaining medicinal liquid.
  • the spray drug delivery device includes:
  • the sleeve is formed with an inner cavity capable of accommodating a barrel of a syringe
  • the nozzle is arranged at the front end of the sleeve and communicates with the inner cavity of the sleeve;
  • a finger press gusset formed at or near the rear end of the casing.
  • the setting of the finger-press pinch plate can ensure that the spray drug delivery device and the syringe are kept together when pushing the drug solution, reduce or eliminate the leakage of the drug solution between them, and prevent the spray drug delivery device from being sprayed off.
  • the spray drug delivery device includes:
  • a sleeve forming a lumen capable of receiving a barrel of a syringe
  • Two nozzles are arranged on the front end of the casing, and are respectively located on the left and right sides of the front end of the casing, and the two nozzles communicate with the inner cavity of the casing.
  • the arrangement of two nozzles allows simultaneous drug delivery to both nasal cavities, ensuring that the same amount of drug solution is delivered to both nasal cavities.
  • the nozzle includes an elbow, one end of the elbow is connected to the front end of the spray drug delivery device, the nozzle core is inserted into the other end of the elbow, and the spray head is sleeved on the other end of the elbow.
  • the elbow is a corrugated pipe, thereby allowing adjustment of the bending angle of the elbow.
  • a nozzle may be included, wherein the nozzle includes a spray head and a nozzle core accommodated in the spray head, wherein the spray head is integrally formed on the casing.
  • the nozzle includes an elbow and a nozzle core, one end of the elbow is connected to the front end of the spray drug delivery device, a boss is formed in the other end of the elbow, and the nozzle core is sleeved onto the boss from the other end of the elbow .
  • the elbow is preferably rotatable relative to the sleeve, thereby allowing the angle of the nozzle to be adjusted relative to the sleeve.
  • the elbow can be a corrugated pipe, so as to facilitate the rotation of the elbow relative to the casing.
  • the angle of the nozzle is fixed relative to the bushing is also within the scope of the present invention, for example, the angle of the nozzle relative to the bushing can be fixed by a matching structure of a cutout and a tab.
  • an observation part is formed on the sleeve, and the syringe can be seen through the observation part.
  • the observation part can facilitate the user to control the amount of medical solution pushed.
  • the observation part is a hollow part or a transparent part formed on the sleeve.
  • the nozzle includes a spray head, and an air suction channel is formed on the spray head.
  • the inspiratory channel allows the user to draw in air while applying the liquid medicine, thereby facilitating deeper application of the liquid medicine.
  • the inhalation channel can also make the user breathe smoothly.
  • the air suction channel is formed by at least one of the following structures: an air suction port and an air suction groove.
  • a spray drug delivery system which comprises the above-mentioned spray drug delivery device and a syringe, and the syringe can be inserted into the inner cavity of the sleeve of the spray drug delivery device.
  • a limit clip is also included, and the limit clip is detachably installed on the plunger of the syringe.
  • Fig. 1 shows a perspective view of a spray drug delivery device and a syringe used with it according to a first embodiment of the present invention.
  • Figure 2 shows a top view of the spray delivery device and syringe shown in Figure 1 .
  • Figure 3 schematically shows the process of inserting the syringe into the spray delivery device.
  • Fig. 4 is a sectional view taken along line A-A in Fig. 2 .
  • Fig. 5 is a sectional view taken along line B-B in Fig. 2 .
  • Fig. 6a is an exploded perspective view of the spray delivery device in Fig. 1 .
  • Figure 6b shows a perspective view of a modified sleeve.
  • Fig. 6c shows a perspective view of an elbow of a modified structure cooperating with the bushing of Fig. 6b.
  • Fig. 7 shows a perspective view of a spray drug delivery device and a syringe used with it according to a second embodiment of the present invention.
  • Fig. 8 is a cross-sectional view of the spray delivery device and syringe shown in Fig. 7 .
  • Fig. 9 shows a perspective view of a spray drug delivery device and a syringe of a modified structure of the second embodiment.
  • Fig. 10 schematically shows the action mode of the spray drug delivery device and the syringe when the limit clip is installed.
  • Fig. 11 shows a perspective view of the limit clip.
  • Fig. 12 shows a perspective view of a spray drug delivery device and a syringe used with it according to a third embodiment of the present invention.
  • FIG. 13 shows an exploded side view of the spray delivery device of FIG. 12 .
  • Fig. 14 shows a perspective view of a spray drug delivery device and a syringe used with it according to a fourth embodiment of the present invention.
  • Fig. 15 shows a partially exploded perspective view of the spray delivery device and syringe shown in Fig. 14 .
  • FIG. 16 shows a cutaway view of the spray delivery device in FIG. 14 .
  • Fig. 17 shows a perspective view of a spray drug delivery device according to a fifth embodiment of the present invention.
  • Fig. 18 shows a perspective view of a spray drug delivery device according to a sixth embodiment of the present invention.
  • FIG. 19 shows an exploded perspective view of the spray delivery device of FIG. 18 .
  • FIG. 20 shows a cross-sectional view of the nozzle in FIG. 18 .
  • Fig. 21 shows a perspective view of a spray drug delivery device according to a seventh embodiment of the present invention.
  • Fig. 22a shows a cross-sectional view of the showerhead in Fig. 21 .
  • Fig. 22b shows a perspective view of the showerhead in Fig. 21 .
  • Fig. 23 shows a perspective view of a modified structure of the spray drug delivery device shown in Fig. 21 .
  • Fig. 24a shows a cross-sectional view of the showerhead in Fig. 23 .
  • FIG. 24b shows a perspective view of the showerhead in FIG. 23 .
  • Fig. 25 shows a perspective view of another modified structure of the spray drug delivery device shown in Fig. 21 .
  • Fig. 26a shows a cross-sectional view of the showerhead in Fig. 25 .
  • FIG. 26b shows a perspective view of the showerhead in FIG. 25 .
  • front refers to the side away from the user
  • rear refers to the side close to the user
  • FIG. 1 to 6 show a spray delivery device 110 and a syringe 120 used with the spray delivery device 110 according to a first embodiment of the present invention.
  • FIG. 2 shows a top view of the spray delivery device 110 and syringe 120 assembly.
  • the spray delivery device 110 comprises a cannula 111 into which a barrel 121 of a syringe 120 can be inserted, as schematically shown in FIG. 3 .
  • FIG. 4 and 5 show cross-sectional views taken along lines A-A and B-B in FIG. 2, respectively.
  • a nozzle core 131 through which the medical solution from the syringe 120 is atomized is provided inside the nozzle 130 .
  • FIG. 6 a shows an exploded perspective view of the spray delivery device 110 to better show the structure of the spray delivery device 110 . It can be seen that a finger press plate 112 is formed at or near the rear end of the sleeve 111 of the spray delivery device 110 .
  • the user pushes the plunger 122 of the syringe 120 with the thumb to push the medical solution in the syringe 120 the user's index finger and middle finger can buckle the finger pressing plate 112 .
  • a hollow part 113 is formed on the sleeve 111, and the setting of the hollow part 113 enables the user to see the scale on the syringe 121 of the syringe 120 which is set in the sleeve 111, thereby helping the user Control the amount of liquid medicine pushed.
  • a transparent material may also be used to form a part of the spray delivery device 110 , or the spray delivery device 110 is entirely made of a transparent material, such as a transparent plastic material, and the like.
  • the finger press plate 112 can adopt various suitable shapes, such as polygonal, circular, etc., all of which are within the scope of the present invention.
  • Two nozzles 130 are provided on the front end of the sleeve 111 .
  • side openings 114 are respectively formed on the left and right sides of the front end of the sleeve 111 , that is, two side openings 114 are formed on the front end.
  • the opening direction of the side opening 114 is at an angle to the axial direction of the casing 111 , preferably perpendicular to the axial direction.
  • An elbow 132 of a nozzle 130 is connected to each side opening 114 .
  • a protruding ring structure is formed on the side opening 114
  • a groove structure is formed on the inner surface of the elbow 132 near the side opening 114 .
  • the nozzle 130 when assembled, is arranged with its longitudinal axis at an angle relative to the longitudinal axis of the sleeve 111, or that the two longitudinal axes are not aligned. Also, the snap fit between the collar structure and the groove structure allows the elbow 132 to rotate relative to the sleeve 111 to adjust the angle that the longitudinal axis of the nozzle 130 makes with respect to the longitudinal axis of the sleeve 111 .
  • connection between the elbow 132 and the side opening 114 can also be connected in other ways, such as intermeshing with threaded structures, and the like.
  • the rotation of the elbow 132 relative to the sleeve 111 can also be realized through other additional or alternative structures, such as will be described in the following embodiments.
  • the elbow 132 and the side opening 114 may also be non-rotatably fixed to each other.
  • a notch 134 is formed at the position of the side opening 114, and a protruding piece 135 is formed on an end connected to the side opening 114 of the elbow 132.
  • Tab 135 fits into notch 134 when 132 is attached to side opening 114 .
  • the elbow 132 cannot rotate, so that the angle of the elbow 132 relative to the sleeve 111 is fixed.
  • the locations of the notch 134 and the protruding piece 135 can also be interchanged, that is, the notch 134 can be formed on the elbow 132 , while the protruding piece 135 can be formed at the corresponding position of the side opening 114 .
  • the user first extracts the medicinal solution from the medicine bottle with the syringe 120 . Then, the needle of the syringe 120 is removed, and the barrel 121 of the syringe 120 is inserted into the lumen of the cannula 111 . Then, the user pushes the plunger 122 of the syringe 120 to push the medical solution in the syringe 121 into the nozzle 130 , where the medical solution is atomized.
  • the liquid medicine atomized through the nozzle 130 is sprayed from the spray head 133 of the nozzle 130, and can be applied to the patient's nasal cavity, oral cavity and other parts.
  • the user pushes the plunger 122 (for example, with the thumb) on the one hand, and buckles the finger pressing plate 112 on the sleeve 111 (for example, with the index finger and middle finger) on the other hand.
  • the syringe 120 is kept against the spray drug delivery device 110, thereby reducing or even eliminating the leakage of the drug solution between the spray drug delivery device 110 and the syringe 120, and the spray drug delivery device 110 It will not be sprayed away due to the pressure of the liquid medicine being pushed out.
  • the spray delivery device 110 of the first embodiment shown has two nozzles 130 and is therefore particularly suitable for nasal delivery. That is, when administering medicine, the two nozzles 130 may be aimed at the two nostrils of the patient, respectively.
  • the two nozzles 130 can be made substantially the same. In this way, when the plunger 122 is pushed, the two nozzles 130 can be supplied with chemical liquid and generate atomized chemical liquid at the same time, and the sprayed atomized chemical liquid can remain substantially the same.
  • the syringe 120 will be in a frontal orientation when the two nozzles 130 are aligned and inserted into the patient's nostrils. A low-back-high stance. In this way, when administering medicine, the liquid medicine will be concentrated at the front end of the syringe 120 , and there will be a certain amount of gas between the liquid medicine and the front end of the plunger 122 .
  • the gas between the front end of the plunger 122 and the liquid medicine will be compressed, and the compressed gas will generate an additional driving force on the liquid medicine, thereby helping to push out the liquid medicine more quickly.
  • the compressed air will be pushed out, and during the process of being pushed out, the pressure of the compressed air can push out the liquid medicine remaining in the spray drug delivery device 110, the syringe 120 and the nozzle 130, thereby realizing The complete spraying of liquid medicine is clean.
  • FIG. 7 to 11 show the structure of the assembly of the nebulizer drug delivery device 210 and the syringe 220 according to the second embodiment of the present invention and its modified structure.
  • the same or corresponding features as those of the first embodiment are denoted by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first embodiment, without further detailed description of the same features .
  • the features described in the first embodiment are also applicable to the second embodiment.
  • the spray delivery device 210 used with the syringe 220 has a single nozzle 230 .
  • the longitudinal axis of the nozzle 230 is substantially consistent with the longitudinal axis of the spray drug delivery device 210 , or is in a straight line.
  • the nozzle 230 includes a head 233 and a nozzle core 231 accommodated in the head 233 .
  • the spray head 233 can be integrally formed with the sleeve 211 of the spray delivery device 210 .
  • the spray head 233 can also be formed separately from the casing 211 and then installed together.
  • a finger-press buckle 212 is formed at the rear end of the sleeve 211, and when pushing the medical solution in the syringe 220, the user can push the plunger 222 of the syringe 220 and buckle the finger-press buckle at the same time. Plate 212, thereby holding spray delivery device 210 and syringe 220 together.
  • FIG. 9 to 11 show schematic diagrams of a modified structure of the second embodiment of the present invention.
  • a limit clip 240 is installed on the syringe 220 for assisting in metering the amount of liquid medicine sprayed out.
  • the limiting clip 240 is installed on the plunger 222 .
  • FIG. 11 shows an exemplary structure of the limiting clip 240 .
  • the length of the plunger 222 is H1 longer than the length of the stop clip 240 , so that the plunger 222 is allowed to be pushed toward the front end.
  • the limit clip 240 will be stuck between the syringe 221 and the plunger 222 , and the limit clip 240 prevents the plunger 222 from being pushed forward further.
  • the drug delivery to one nasal cavity is completed.
  • remove the limit clip 240 so that the plunger 122 can be continuously pushed toward the front end until the medicinal liquid is exhausted, such as pushing the plunger 222 toward the front end as shown in FIG. Push forward the distance H2 to exhaust the medicinal liquid.
  • the setting of the limit clip 240 will help to distribute the medical solution in the syringe 220 to ensure that the amount of the medical solution delivered to the two nasal cavities is substantially equal.
  • Figures 12 and 13 show a spray delivery device 310 and a syringe 320 for use therewith in accordance with a third embodiment of the present invention.
  • the same or corresponding features as those of the first and second embodiments are denoted by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first and second embodiments, without referring to the same characteristics are described in detail. Unless stated to the contrary, the features described in the first and second embodiments are also applicable to the third embodiment.
  • the spray delivery device 310 in the third embodiment can be used with a syringe 320 and has a single nozzle 330 at the front end of the spray delivery device 310 .
  • the axis direction of the nozzle 330 of the spray drug delivery device 310 of the third embodiment is at an angle to the axis direction of the spray drug delivery device 310 main body (ie, its sleeve), as shown in FIG. 13 of.
  • the nozzle 330 also includes a nozzle core 331 , an elbow 332 accommodating the nozzle core 331 and connected to the main body of the spray drug delivery device 310 , and a spray head 333 sleeved on the nozzle core 331 and the elbow 332 .
  • FIG. 14 to 16 show a fourth embodiment of a spray delivery device 410 of the present invention and a syringe 420 for use therewith.
  • the same or corresponding feature parts as those of the first to third embodiments are denoted by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first to third embodiments, without referring to the same characteristics are described in detail. Unless otherwise stated, the features described in the first to third embodiments are also applicable to the fourth embodiment.
  • the spray drug delivery device 410 includes two nozzles 430, each of which includes a nozzle body 432, and the nozzle body 432 is integrally formed with the spray drug delivery device 410, as can be seen from FIG. It can be seen more clearly in the cross-sectional view shown.
  • the nozzle body 432 of the nozzle 430 is arc-shaped as a whole, so as to facilitate manufacture.
  • the nozzle 430 also includes a nozzle core 431 inserted into the nozzle body 432 .
  • the structure of the integrally formed nozzle 430 helps to simplify the structure and reduce the number of parts.
  • Fig. 17 shows a spray drug delivery device 510 according to a fifth embodiment of the present invention.
  • the same or corresponding feature parts as those of the first to fourth embodiments are indicated by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first to fourth embodiments, without referring to the same characteristics are described in detail. Unless otherwise stated, the features described in the first to fourth embodiments are also applicable to the fifth embodiment.
  • the nozzle 530 includes a bellows 532 to serve as a nozzle body of the nozzle 530, and the bellows 532 is connected to the body of the spray drug delivery device 510.
  • corrugated tube 532 as the body of the nozzle 530 can facilitate molding.
  • the corrugated tube 532 can be made straight during molding, and can be bent to a desired curvature when used.
  • the bellows 532 can also adjust its bending angle, so that it can be applied to various applications.
  • the spray drug delivery device 610 includes a sleeve 611 as its main body, a finger pressing plate 612 is formed at the rear end of the sleeve 611 , and a nozzle 630 is installed at the front end of the sleeve 611 . Similar to the first embodiment, the nozzle 630 can be connected to the sleeve 611 by means such as a snap ring-groove fit (as shown in the figures), threaded connection or the like.
  • a nozzle 630 includes an elbow 632 and a nozzle core 631 inserted in the elbow 632 .
  • 20 shows a cross-sectional view of the nozzle 630, which shows that a boss 633 is formed in the elbow 632, and the nozzle core 631 inserted in the elbow 632 can be sleeved on the boss 633, so that the nozzle core 631 is Fixation of elbow 632.
  • the nozzle 630 with the above structure can be applied to the spray drug delivery devices of the first to fifth embodiments described above.
  • Figures 21 to 26b show a spray drug delivery device 710 of the seventh embodiment of the present invention and its variants.
  • the same or corresponding feature parts as those of the first to sixth embodiments are indicated by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first to sixth embodiments, without referring to the same characteristics are described in detail. Unless otherwise stated, the features described in the first to sixth embodiments are also applicable to the seventh embodiment.
  • the spray drug delivery device 710 of the seventh embodiment at least one, preferably a plurality of suction ports 734 are formed on the spray head 733 of the nozzle.
  • the suction port 734 is arranged around the circumference of the spray head 733 .
  • the suction port 734 is generally rectangular.
  • the inhalation port 734 By providing the inhalation port 734, when the spray drug delivery device 710 is used to administer medicine to the user's nasal cavity, the inhalation port 734 provides a passage for inhaling air.
  • the inhaled air helps to bring the atomized medicinal solution deep into the nasal cavity, which in turn facilitates the absorption of the medicinal solution by the nasal mucosa.
  • the setting of the suction port 734 can also keep the user's breathing smooth during the administration process, which is especially useful for children and the like.
  • FIG. 23-24b show a modified structure of the spray drug delivery device 710 of the seventh embodiment. Wherein, several circular suction ports 734' are provided on the shower head 733'.
  • 25-26b show another modified structure of the spray drug delivery device 710 of the seventh embodiment.
  • a plurality of suction grooves 734" are formed on the outer peripheral surface of the spray head 733". These suction slots 734" extend from the front end to the rear end of the spray head 733". These inhalation slots 734" can form a pathway for inhaling air when administering a drug to the user's nasal cavity.

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  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Otolaryngology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

一种喷雾给药装置（110）包括：套管（111），套管（111）形成有内腔，内腔能够容纳注射器（120）的针筒（121）；以及至少一个喷嘴（130），喷嘴（130）设置在套管（111）的前端，并且与套管（111）的内腔连通。喷嘴（130）的轴线方向相对于套管（111）的轴线方向成角度。在套管（111）的后端或邻近后端处还可形成指压扣板（112）。还可在套管（111）的前端设置两个喷嘴（130）。喷雾给药装置（110）可实现药液的充分喷射，均匀给药，以及防泄漏。还涉及一种包括喷雾给药装置（110）的喷雾给药系统。

Description

喷雾给药装置和包括该装置的喷雾给药系统 技术领域
本申请涉及一种给药装置，特别是一种能够与注射器配合使用并以喷雾形式向人体递送药物的给药装置。
背景技术
注射器是医疗领域中常用的医疗器具，用于将药物诸如人体中，以进行疾病治疗、疫苗植入等操作。目前市场上存在一种与注射器配合使用的喷雾给药装置，在将药液吸入到注射器中之后，该喷雾给药装置能够配合到注射器上，然后将喷雾给药装置的喷嘴对准鼻腔、口腔或其它适于给药的人体部位，通过推动注射器，使药液雾化并递送到人体中。与传统的注射器给药相比，这种喷雾给药装置能够均匀地将药液递送到需要的部位，而且可以减少对人体产生的创伤。
在应用过程中，发现现有的喷雾给药装置还存在一些问题。例如，在推动注射器以递送药液时，注射器内的压力会快速增大，造成喷雾给药装置和注射器之间的连接松动，导致在两者之间产生泄漏，严重的会导致喷雾给药装置与注射器互相脱离，甚至会将喷雾给药装置喷飞，产生安全隐患。
又比如，在某些应用场合，例如对使用人的鼻腔进行喷射时，喷雾给药装置和注射器的朝向不合理，注射器采取前高后低的姿态，这样的话位于注射器前端的将是空气，首先被喷出的也是空气，然后才是药液被喷出。因此，残留在喷雾给药装置和注射器中的药液会比较多，导致用药量不准确，同时也会造成药液的浪费。
此外，在对鼻腔进行给药时，需要对两个鼻腔分别进行给药。这样的操作比较繁琐，而且还难以保证对两个鼻腔的给药量相等，有时甚至两个鼻腔的给药量有较大差异。
因此，存在对喷雾给药装置的结构进行进一步改进的需求，以克服上述现有的喷雾给药装置所存在的技术问题。
发明内容
本发明是为解决以上所述现有技术所存在的技术问题而作出的。本发明的目的是提供一种结构改进的喷雾给药装置，其在喷雾给药装置与注射器相套接的时候避免它们互相脱开或在它们之间发生泄漏的问题。另外，本发明还通过对喷雾给药装置的结构进行改进，实现对该装置和注射器中药液的充分喷射。进一步地，该改进结构的喷雾给药装置还能实现对两个鼻腔的均匀给药。
本发明的喷雾给药装置包括：
套管，该套管形成有内腔，内腔能够容纳注射器的针筒；以及
至少一个喷嘴，该喷嘴设置在套管的前端，并且与套管的内腔连通；
其中，该喷嘴的轴线方向相对于套管的轴线方向成角度。
在上述结构中，喷嘴的轴线方向相对于套管的轴线方向成角度，因而相对于插入在套管中的注射器的轴线方向也成同样的角度。这样的话，当使用喷雾给药装置给鼻腔输送药液时，注射器将呈前低后高的姿态。此时，药液会聚集在注射器的前端，而在药液后部会有气体。当推送药液时，该气体会被压缩，其压缩力会提供额外的推动药液的动力。而且，在推送药液的结尾时，该压缩气体会起到吹扫药液的作用，从而将残留的药液推尽。
本发明的另一种结构中，喷雾给药装置包括：
套管，套管形成有内腔，内腔能够容纳注射器的针筒；
至少一个喷嘴，喷嘴设置在套管的前端，并且与套管的内腔连通；以及
指压扣板，指压扣板形成在套管的后端或邻近后端。
指压扣板的设置可在推送药液时保证喷雾给药装置和注射器保持在一起，减少或消除它们之间的药液泄漏，还能防止喷雾给药装置被喷飞。
本发明的又一种结构中，喷雾给药装置包括：
套管，套管形成有内腔，内腔能够容纳注射器的针筒；以及
两个喷嘴，两个喷嘴设置在套管的前端，并分别位于套管的前端的左右两侧，并且两个喷嘴与套管的内腔连通。
两个喷嘴的设置允许对两个鼻腔同时送药，确保递送给两个鼻腔的药液量相同。
较佳地，喷嘴包括弯管，弯管的一端连接在喷雾给药装置的前端，弯管的另一端中插入有喷嘴芯，并且喷头套设在弯管的另一端上。更佳地，弯管为 波纹管，从而允许对弯管的弯曲角度进行调节。
较佳地，可以包括一个喷嘴，其中，喷嘴包括喷头和容纳在喷头中的喷嘴芯，其中，喷头一体形成于套管上。
较佳地，喷嘴包括弯管和喷嘴芯，弯管的一端连接在喷雾给药装置的前端，弯管的另一端中形成有凸柱，喷嘴芯从弯管的另一端套设到凸柱上。其中，该弯管较佳地可相对于套管转动，从而允许调节喷嘴相对于套管的角度。进一步较佳地，弯管可以是波纹管，以有助于弯管相对于套管的转动。
当然，喷嘴相对于套管角度固定的情况也在本发明的范围之中，例如可通过切口-凸片的配合结构来固定喷嘴相对于套管的角度。
较佳地，套管上形成有观察部，透过观察部能够看到注射器。这样，该观察部可便于使用人控制推送的药液量。
较佳地，观察部为形成在套管上的镂空部或者透明部分。
较佳地，喷嘴包括喷头，喷头上形成有吸气通道。该吸气通道允许使用人在施加药液时吸入空气，从而有助于更深地施加药液。而且，该吸气通道还可使使用人呼吸顺畅。
具体地，吸气通道由以下结构中的至少一种形成：吸气口和吸气槽。
还涉及一种喷雾给药系统，该喷雾给药系统包括如上所述的喷雾给药装置以及注射器，注射器能够插入到喷雾给药装置的套管的内腔中。
较佳地，还包括限位卡子，限位卡子可拆卸地安装在注射器的柱塞上。
附图说明
附图中示出了本发明的非限制性的较佳实施结构，结合附图，可使本发明的特征和优点更加明显。其中：
图1示出了本发明的第一实施例的喷雾给药装置以及与其一起使用的注射器的立体图。
图2示出了图1所示的喷雾给药装置和注射器的俯视图。
图3示意性地示出了将注射器插入到喷雾给药装置中的过程。
图4是沿图2中的线A-A得到的剖视图。
图5是沿图2中的线B-B得到的剖视图。
图6a是图1中的喷雾给药装置的分解立体图。
图6b示出了变型结构的套管的立体图。
图6c示出了与图6b的套管相配合的变型结构的弯管的立体图。
图7示出了本发明的第二实施例的喷雾给药装置以及与其一起使用的注射器的立体图。
图8是图7所示喷雾给药装置和注射器的剖视图。
图9示出了第二实施例的变型结构的喷雾给药装置和注射器的立体图。
图10示意性地示出了安装有限位卡子时喷雾给药装置和注射器的动作方式。
图11示出了限位卡子的立体图。
图12示出了本发明的第三实施例的喷雾给药装置以及与其一起使用的注射器的立体图。
图13示出了图12中的喷雾给药装置的分解侧视图。
图14示出了本发明的第四实施例的喷雾给药装置以及与其一起使用的注射器的立体图。
图15示出了图14所示的喷雾给药装置和注射器的局部分解立体图。
图16示出了图14中的喷雾给药装置的剖切图。
图17示出了本发明的第五实施例的喷雾给药装置的立体图。
图18示出了本发明的第六实施例的喷雾给药装置的立体图。
图19示出了图18的喷雾给药装置的分解立体图。
图20示出了图18中的喷嘴的剖视图。
图21示出了本发明的第七实施例的喷雾给药装置的立体图。
图22a示出了图21中的喷头的剖视图。
图22b示出了图21中的喷头的立体图。
图23示出了图21所示的喷雾给药装置一种变型结构的立体图。
图24a示出了图23中的喷头的剖视图。
图24b示出了图23中的喷头的立体图。
图25示出了图21所示的喷雾给药装置另一种变型结构的立体图。
图26a示出了图25中的喷头的剖视图。
图26b示出了图25中的喷头的立体图。
具体实施方式
为了便于理解本发明，下面将结合附图对本发明的具体实施方式进行详细描述。应当理解，附图中所示的仅仅是本发明的较佳实施例，其不应理解为对本发明的范围的限制。本领域的技术人员可以在附图所示的实施例的基础上对本发明进行各种显而易见的修改、变型、等效替换，并且在不相矛盾的前提下，以下所描述的不同实施例中的技术特征可以互相任意地组合，而这些都落在本发明的范围之内。
在以下的对本发明的具体描述中，所使用的诸如“前”、“后”之类的表示方向和朝向的用语是在喷雾给药装置和注射器在使用过程中以使用人为参照而言的。其中，“前”指的是远离使用人的一侧，“后”指的是靠近使用人的一侧。
<第一实施例>
图1～6示出了本发明的第一实施例的喷雾给药装置110以及与该喷雾给药装置110一起使用的注射器120。图2示出了该喷雾给药装置110和注射器120的组件的俯视图。
喷雾给药装置110包括套管111，注射器120的针筒121能够插入到套管111的内腔中，如图3中示意性地示出的那样。
图4和5分别示出了沿图2中的线A-A和B-B得到的剖视图。如图4中所示，在喷嘴130内设置有喷嘴芯131，来自注射器120的药液经由该喷嘴芯131而被雾化。
图6a示出了喷雾给药装置110的分解立体图，以更好地显示出该喷雾给药装置110的结构。可以看到，在喷雾给药装置110的套管111的后端或在后端附近形成有指压扣板112。当使用人用拇指推压注射器120的柱塞122以对注射器120中的药液进行推送时，使用人的食指和中指可扣住该指压扣板112。较佳地，在套管111上形成有镂空部113，该镂空部113的设置使得使用人能够看到被套在套管111中的注射器120的针筒121上的刻度，从而有助于使用人控制所推送的药液量。
作为对镂空部113的替代，也可以采用透明材料来形成喷雾给药装置110的一部分，或者喷雾给药装置110完全有透明材料制成，例如由透明的塑料材料制成，等等。
指压扣板112可以采用各种合适的形状，例如多边形、圆形等，这些都在本发明的范围之中。
在套管111的前端上设置有两个喷嘴130。具体来说，在套管111的该前端的左右两侧分别形成有侧开口114，即在该前端上形成有两个侧开口114。该侧开口114的开口方向与套管111的轴线方向成角度，较佳地垂直于该轴线方向。
在每个侧开口114上连接有喷嘴130的弯管132。举例来说，侧开口114上形成有凸环结构，相对应地，在弯管132的靠近侧开口114的一端的内表面上形成有凹槽结构。在将弯管132安装到侧开口114上时，凸环结构和凹槽结构之间形成卡扣配合，实现弯管132与侧开口114之间的连接。喷嘴芯131插入在弯管132另一端内，喷头133覆盖在弯管132的该另一端上，由此组装形成喷嘴130。如从图5中更清楚地看出的，在组装好之后，将喷嘴130布置成其纵向轴线相对于套管111的纵向轴线成角度，或者说两根纵向轴线不在一条直线上。并且，凸环结构和凹槽结构之间的卡扣配合允许弯管132相对于套管111转动，从而以调节喷嘴130的纵向轴线相对于套管111的纵向轴线所成的角度。
弯管132和侧开口114之间的连接也可通过其它方式连接，例如通过螺纹结构互相啮合，等等。还可以通过其它附加的或替代的结构来实现弯管132相对于套管111的转动，例如将在之后的实施例中所描述的。
弯管132和侧开口114之间也可以是不可转动地互相固定。
例如，如图6b和6c中所示的，在侧开口114的位置处形成有缺口部134，而在弯管132的与侧开口114相连接的一端上形成有凸片135，在将弯管132连接到侧开口114上时，凸片135配合到缺口部134中。通过缺口部134和凸片135之间的相互作用，使得弯管132不能转动，进而使弯管132相对于套管111的角度固定。缺口部134和凸片135的设置部位也可互换，即，缺口部134可形成在弯管132上，而凸片135则形成在侧开口114的对应位置处。
下面将描述喷雾给药装置110的使用方法。
使用人先用注射器120从药瓶中抽取药液。然后，将注射器120的针头移除，将注射器120的针筒121插入到套管111的内腔中。然后，使用人推动注射器120的柱塞122，将针筒121中的药液推到喷嘴130中，药液在喷嘴130中被雾化。经喷嘴130雾化的药液从喷嘴130的喷头133喷出，并可施加到诸如患者的鼻腔、口腔等部位。
在推送药液的过程中，使用人一方面抵推柱塞122(例如用拇指)，另一方面扣住套管111上的指压扣板112(例如用食指和中指)。这样，在推送药液的过程中，保持注射器120抵靠在喷雾给药装置110中，从而可减少甚至消除发生在喷雾给药装置110与注射器120之间的药液泄漏，喷雾给药装置110也不会因为被推出的药液的压力而被喷飞。
进一步地，所示第一实施例的喷雾给药装置110具有两个喷嘴130，因此尤其适用于对鼻腔给药。即，在给药时，可将两个喷嘴130分别对准患者的两个鼻孔。两个喷嘴130可以制作成基本相同，这样的话在推动柱塞122时，可以同时向两个喷嘴130提供药液并生成雾化药液，且喷出的雾化药液能够保持基本相同。
另外，由于喷嘴130的纵向轴线与套管111的纵向轴线(同时也是注射器120的纵向轴线)成角度，因此当将两个喷嘴130对准并插入到患者的鼻孔中时，注射器120将呈前低后高的姿态。这样，在给药时，药液将集中在注射器120的前端，而在药液和柱塞122的前端之间会有一定量的气体。此时，若推动柱塞122，则柱塞122的前端和药液之间的气体会被压缩，该压缩的气体对药液产生附加的推动力，从而有助于更加快速地将药液推出。而在推药程序的结尾，压缩空气将被推出，在被推出的过程中，该压缩空气的压力可以将残留在喷雾给药装置110、注射器120和喷嘴130中的药液都推出，从而实现药液的完全喷射干净。
<第二实施例>
图7～11示出了本发明的第二实施例的喷雾给药装置210和注射器220的组件的结构及其变型结构。其中，与第一实施例相同或对应的特征部分用相 同或类似的附图标记来表示，并且以下的公开内容中主要描述与第一实施例不同的特征，而不对相同的特征再作详细描述。除非有相反的描述，第一实施例中描述的特征同样适用于第二实施例。
如图7和8中所示的，与注射器220一起使用的喷雾给药装置210具有单个喷嘴230。该喷嘴230的纵向轴线与喷雾给药装置210的纵向轴线基本一致，或者说成一条直线。喷嘴230包括喷头233和容纳在喷头233中的喷嘴芯231。在图中所示的较佳结构中，喷头233可与喷雾给药装置210的套管211一体形成。当然，喷头233也可与套管211分开形成，然后再安装到一起。
与第一实施例相同，在套管211的后端形成有指压扣板212，在推送注射器220中的药液时，使用人可以在推动注射器220的柱塞222的同时扣住指压扣板212，从而将喷雾给药装置210和注射器220保持在一起。
图9～11示出了对本发明的第二实施例的一种变型结构的示意图。具体里来说，在注射器220上安装限位卡子240，用于辅助计量所喷出的药液量。具体来说，该限位卡子240安装在柱塞222上。图11示出了该限位卡子240的一个示例性结构。
如图10所示，在初始位置，柱塞222的长度比限位卡子240的长度多出H1，因此，允许朝着前端的方向推动柱塞222。当将柱塞222向前推距离H1之后，限位卡子240将被卡在针筒221和柱塞222之间，此时限位卡子240阻止继续向前推动柱塞222。此时，完成对一个鼻腔的送药。接着，在对另一个鼻腔进行送药时，移除限位卡子240，从而可向着前端的方向继续推动柱塞122，直到将药液推尽，例如图10中所示的将柱塞222向前推距离H2，以推尽药液。
限位卡子240的设置将有助于对注射器220中的药液进行分配，以确保递送到两个鼻腔中的药液量基本相等。
<第三实施例>
图12和13示出了本发明的第三实施例的喷雾给药装置310和与之一起使用的注射器320。其中，与第一和第二实施例相同或对应的特征部分用相同或类似的附图标记来表示，并且以下的公开内容中主要描述与第一和第二实施 例不同的特征，而不对相同的特征再作详细描述。除非有相反的描述，第一和第二实施例中描述的特征同样适用于第三实施例。
第三实施例中的喷雾给药装置310能与注射器320配合使用，并且在喷雾给药装置310的前端具有单个喷嘴330。与第二实施例不同的是，第三实施例的喷雾给药装置310的喷嘴330的轴线方向与喷雾给药装置310主体(即其套管)的轴线方向成角度，如图13中所示的。
喷嘴330也包括喷嘴芯331、容纳喷嘴芯331并连接于喷雾给药装置310的主体的弯管332、以及套设在喷嘴芯331和弯管332上的喷头333。
<第四实施例>
图14～16示出了本发明的第四实施例的喷雾给药装置410和与之一起使用的注射器420。其中，与第一至第三实施例相同或对应的特征部分用相同或类似的附图标记来表示，并且以下的公开内容中主要描述与第一至第三实施例不同的特征，而不对相同的特征再作详细描述。除非有相反的描述，第一至第三实施例中描述的特征同样适用于第四实施例。
在第四实施例中，喷雾给药装置410包括两个喷嘴430，这两个喷嘴430各自包括喷嘴本体432，且该喷嘴本体432与喷雾给药装置410一体地形成，如能够从图16所示的剖视图中更加清楚地看出的。较佳地，喷嘴430的喷嘴本体432整体呈弧形，以便于制造。
喷嘴430还包括喷嘴芯431，该喷嘴芯431插入到喷嘴本体432中。
该一体形成的喷嘴430的结构有助于简化结构，减少零件数量。
<第五实施例>
图17示出了本发明的第五实施例的喷雾给药装置510。其中，与第一至第四实施例相同或对应的特征部分用相同或类似的附图标记来表示，并且以下的公开内容中主要描述与第一至第四实施例不同的特征，而不对相同的特征再作详细描述。除非有相反的描述，第一至第四实施例中描述的特征同样适用于第五实施例。
在第五实施例的喷雾给药装置510中，喷嘴530包括波纹管532，以用作 喷嘴530的喷嘴本体，并且，该波纹管532连接到喷雾给药装置510的本体上。
使用波纹管532作为喷嘴530的本体，可方便成型，在成型时该波纹管532可以做成直的，在使用时可根据需要弯折到所要的弯度。另外，该波纹管532还允许调整其弯曲角度，从而可适用于多种应用场合。
<第六实施例>
图18～20示出了本发明的第六实施例的喷雾给药装置610。其中，与第一至第五实施例相同或对应的特征部分用相同或类似的附图标记来表示，并且以下的公开内容中主要描述与第一至第五实施例不同的特征，而不对相同的特征再作详细描述。除非有相反的描述，第一至第五实施例中描述的特征同样适用于第六实施例。
喷雾给药装置610包括作为其本体部分的套管611，在套管611的后端形成有指压扣板612，在套管611的前端安装有喷嘴630。与第一实施例类似，该喷嘴630可通过诸如卡环-凹槽配合(如图中所示的)、螺纹连接之类的方式连接到套管611。
在第六实施例中，喷嘴630包括弯管632和插入在该弯管632中的喷嘴芯631。图20示出了喷嘴630的剖视图，其中显示，在弯管632中形成有凸柱633，插入在弯管632中的喷嘴芯631能够套设在该凸柱633上，从而实现喷嘴芯631在弯管632的固定。
上述结构的喷嘴630可应用于以上所述的第一～第五实施例的喷雾给药装置中。
<第七实施例>
图21～26b示出了本发明的第七实施例的喷雾给药装置710及其变型。其中，与第一至第六实施例相同或对应的特征部分用相同或类似的附图标记来表示，并且以下的公开内容中主要描述与第一至第六实施例不同的特征，而不对相同的特征再作详细描述。除非有相反的描述，第一至第六实施例中描述的特征同样适用于第七实施例。
如图21～22b所示的，在第七实施例的喷雾给药装置710中，其喷嘴的 喷头733上形成有至少一个、较佳地多个吸气口734。该吸气口734围绕着喷头733的周向布置。在图22a和22b所示的一种示例中，吸气口734呈大致矩形。
通过设置吸气口734，当使用喷雾给药装置710对使用人的鼻腔进行给药时，吸气口734提供了吸入空气的通路。所吸入的空气有助于将雾化的药液带入到鼻腔深处，进而有利于鼻腔黏膜对药液的吸收。而且，该吸气口734的设置还可在给药的过程中保持使用人呼吸顺畅，这对于小孩等来说尤其有用。
图23～24b示出了第七实施例的喷雾给药装置710的一种变型结构。其中，在喷头733’上设置有若干个呈圆形的吸气口734’。
图25～26b示出了第七实施例的喷雾给药装置710的另一种变型结构。其中，在喷头733”的外周表面上形成有多个吸气槽734”。这些吸气槽734”从喷头733”的前端延伸到后端。当对使用人的鼻腔进行给药时，这些吸气槽734”能够形成用于吸入空气的通路。

Claims (15)

  1. 一种喷雾给药装置，其特征在于，所述喷雾给药装置包括：
    套管，所述套管形成有内腔，所述内腔能够容纳注射器的针筒；以及
    至少一个喷嘴，所述喷嘴设置在所述套管的前端，并且与所述套管的所述内腔连通；
    其中，所述至少一个喷嘴的轴线方向相对于所述套管的轴线方向成角度。
  2. 一种喷雾给药装置，其特征在于，所述喷雾给药装置包括：
    套管，所述套管形成有内腔，所述内腔能够容纳注射器的针筒；
    至少一个喷嘴，所述喷嘴设置在所述套管的前端，并且与所述套管的所述内腔连通；以及
    指压扣板，所述指压扣板形成在所述套管的后端或邻近所述后端。
  3. 一种喷雾给药装置，其特征在于，所述喷雾给药装置包括：
    套管，所述套管形成有内腔，所述内腔能够容纳注射器的针筒；以及
    两个喷嘴，所述两个喷嘴设置在所述套管的前端，并分别位于所述套管的所述前端的左右两侧，并且所述两个喷嘴与所述套管的所述内腔连通。
  4. 如权利要求1～3中任一项所述的喷雾给药装置，其特征在于，所述喷嘴包括弯管，所述弯管的一端连接在所述喷雾给药装置的所述前端，所述弯管的另一端中插入有喷嘴芯，并且喷头套设在所述弯管的所述另一端上。
  5. 如权利要求4所述的喷雾给药装置，其特征在于，所述喷嘴能够相对于所述套管转动。
  6. 如权利要求5所述的喷雾给药装置，其特征在于，所述弯管为波纹管。
  7. 如权利要求1或2所述的喷雾给药装置，其特征在于，包括一个所述喷嘴，其中，所述喷嘴包括喷头和容纳在所述喷头中的喷嘴芯，其中，所述喷头一体形成于所述套管上。
  8. 如权利要求1～3中任一项所述的喷雾给药装置，其特征在于，所述喷嘴包括弯管和喷嘴芯，所述弯管的一端连接在所述喷雾给药装置的所述前端，所述弯管的另一端中形成有凸柱，所述喷嘴芯从所述弯管的所述另一端套设到所述凸柱上。
  9. 如权利要求8所述的喷雾给药装置，其特征在于，所述弯管为波纹管。
  10. 如权利要求1～3中任一项所述的喷雾给药装置，其特征在于，所述套管上形成有观察部，透过所述观察部能够看到所述注射器。
  11. 如权利要求10所述的喷雾给药装置，其特征在于，所述观察部为形成在所述套管上的镂空部或者透明部分。
  12. 如权利要求1～3中任一项所述的喷雾给药装置，其特征在于，所述喷嘴包括喷头，所述喷头上形成有吸气通道。
  13. 如权利要求12所述的喷雾给药装置，其特征在于，所述吸气通道由以下结构中的至少一种形成：吸气口和吸气槽。
  14. 一种喷雾给药系统，其特征在于，所述喷雾给药系统包括：如权利要求1～13中任一项所述的喷雾给药装置；以及注射器，所述注射器能够插入到所述喷雾给药装置的所述套管的内腔中。
  15. 如权利要求14所述的喷雾给药系统，其特征在于，还包括限位卡子，所述限位卡子可拆卸地安装在所述注射器的柱塞上。
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CN113893418B (zh) * 2021-12-02 2022-07-12 时新(上海)产品设计有限公司 喷剂装置
WO2023192691A2 (en) * 2022-04-01 2023-10-05 Wake Forest University Health Sciences Methods and formulations for intranasal delivery of insulin in the treatment of diabetic eye disease
CN115445062B (zh) * 2022-09-16 2023-12-05 南阳市口腔医院 一种医用鼻腔给药装置
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105636629A (zh) * 2013-10-11 2016-06-01 B.R.I.O.耳鼻喉科学实验室生物医学研究有限责任公司 用于递送气雾剂物质的装置
US20170333922A1 (en) * 2014-11-14 2017-11-23 The Technology Partnership Plc Low cost impinging jet nozzle
CN209734745U (zh) * 2019-02-12 2019-12-06 贵州省人民医院 喷药器
CN210813439U (zh) * 2019-08-26 2020-06-23 首都医科大学附属北京安贞医院 鼻腔嗅裂区精准给药装置
CN113350634A (zh) * 2021-07-16 2021-09-07 丁要武 喷雾给药装置和包括该装置的喷雾给药系统
CN216169251U (zh) * 2021-07-16 2022-04-05 丁要武 喷雾给药装置和包括该装置的喷雾给药系统

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105636629A (zh) * 2013-10-11 2016-06-01 B.R.I.O.耳鼻喉科学实验室生物医学研究有限责任公司 用于递送气雾剂物质的装置
US20170333922A1 (en) * 2014-11-14 2017-11-23 The Technology Partnership Plc Low cost impinging jet nozzle
CN209734745U (zh) * 2019-02-12 2019-12-06 贵州省人民医院 喷药器
CN210813439U (zh) * 2019-08-26 2020-06-23 首都医科大学附属北京安贞医院 鼻腔嗅裂区精准给药装置
CN113350634A (zh) * 2021-07-16 2021-09-07 丁要武 喷雾给药装置和包括该装置的喷雾给药系统
CN216169251U (zh) * 2021-07-16 2022-04-05 丁要武 喷雾给药装置和包括该装置的喷雾给药系统

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