WO2023284852A1 - 喷雾给药装置和包括该装置的喷雾给药系统 - Google Patents
喷雾给药装置和包括该装置的喷雾给药系统 Download PDFInfo
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- WO2023284852A1 WO2023284852A1 PCT/CN2022/105940 CN2022105940W WO2023284852A1 WO 2023284852 A1 WO2023284852 A1 WO 2023284852A1 CN 2022105940 W CN2022105940 W CN 2022105940W WO 2023284852 A1 WO2023284852 A1 WO 2023284852A1
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- WIPO (PCT)
- Prior art keywords
- spray
- delivery device
- drug delivery
- nozzle
- syringe
- Prior art date
Links
- 239000007921 spray Substances 0.000 title claims abstract description 136
- 238000001647 drug administration Methods 0.000 title abstract description 7
- 239000003814 drug Substances 0.000 claims abstract description 40
- 238000012377 drug delivery Methods 0.000 claims description 82
- 229940079593 drug Drugs 0.000 claims description 13
- 239000007788 liquid Substances 0.000 abstract description 32
- 238000005507 spraying Methods 0.000 abstract description 4
- 210000003928 nasal cavity Anatomy 0.000 description 17
- 239000000243 solution Substances 0.000 description 11
- 210000003811 finger Anatomy 0.000 description 10
- 239000008155 medical solution Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 230000008569 process Effects 0.000 description 5
- 238000003825 pressing Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000005452 bending Methods 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
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- 239000012780 transparent material Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
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- 230000006835 compression Effects 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003434 inspiratory effect Effects 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
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- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
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- 229920003023 plastic Polymers 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
- A61M11/007—Syringe-type or piston-type sprayers or atomisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
- B05B1/14—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with multiple outlet openings; with strainers in or outside the outlet opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
- B05B11/025—Membranes or pistons acting on the contents inside the container, e.g. follower pistons with stepwise advancement of the piston, e.g. for spraying a predetermined quantity of content
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
- A61M16/0666—Nasal cannulas or tubing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0618—Nose
Definitions
- the present application relates to a drug delivery device, especially a drug delivery device that can be used in conjunction with a syringe and deliver medicine to a human body in the form of a spray.
- Syringes are commonly used medical devices in the medical field, and are used to inject drugs into the human body for disease treatment, vaccine implantation and other operations.
- a spray drug delivery device used in conjunction with a syringe on the market. After the liquid medicine is sucked into the syringe, the spray drug delivery device can be fitted to the syringe, and then the nozzle of the spray drug delivery device is aimed at the nasal cavity and oral cavity. Or other parts of the human body suitable for drug administration, by pushing the syringe, the drug solution is atomized and delivered to the human body.
- this spray drug delivery device can evenly deliver the drug solution to the required site, and can reduce the trauma to the human body.
- the orientation of the spray drug delivery device and the syringe is unreasonable, and the syringe adopts a posture of high front and low rear.
- the front end of the syringe will be air. What is ejected is also air, and then the liquid medicine is ejected. Therefore, there will be more medicinal liquid remaining in the spray drug delivery device and the syringe, resulting in inaccurate dosage and waste of medicinal liquid.
- the present invention is made to solve the technical problems in the above-mentioned prior art.
- the object of the present invention is to provide a spray drug delivery device with improved structure, which avoids the problems of disengagement or leakage between the spray drug delivery device and the syringe when they are socketed.
- the present invention also improves the structure of the spray drug delivery device to realize sufficient spraying of the drug solution in the device and the syringe.
- the spray drug delivery device with the improved structure can also realize uniform drug delivery to the two nasal cavities.
- the spray drug delivery device of the present invention comprises:
- a sleeve forming a lumen capable of receiving a barrel of a syringe
- At least one nozzle which is arranged at the front end of the casing and communicates with the inner cavity of the casing
- the axial direction of the nozzle is angled relative to the axial direction of the sleeve.
- the axial direction of the nozzle is angled with respect to the axial direction of the cannula, and thus also at the same angle with respect to the axial direction of the syringe inserted in the cannula.
- the syringe will be in a low-front and high-back posture.
- the liquid medicine will collect at the front of the syringe, and there will be gas at the back of the liquid medicine.
- the gas is compressed, and its compression force provides additional power to push the liquid.
- the compressed gas will play a role in purging the medicinal liquid, thereby pushing away the remaining medicinal liquid.
- the spray drug delivery device includes:
- the sleeve is formed with an inner cavity capable of accommodating a barrel of a syringe
- the nozzle is arranged at the front end of the sleeve and communicates with the inner cavity of the sleeve;
- a finger press gusset formed at or near the rear end of the casing.
- the setting of the finger-press pinch plate can ensure that the spray drug delivery device and the syringe are kept together when pushing the drug solution, reduce or eliminate the leakage of the drug solution between them, and prevent the spray drug delivery device from being sprayed off.
- the spray drug delivery device includes:
- a sleeve forming a lumen capable of receiving a barrel of a syringe
- Two nozzles are arranged on the front end of the casing, and are respectively located on the left and right sides of the front end of the casing, and the two nozzles communicate with the inner cavity of the casing.
- the arrangement of two nozzles allows simultaneous drug delivery to both nasal cavities, ensuring that the same amount of drug solution is delivered to both nasal cavities.
- the nozzle includes an elbow, one end of the elbow is connected to the front end of the spray drug delivery device, the nozzle core is inserted into the other end of the elbow, and the spray head is sleeved on the other end of the elbow.
- the elbow is a corrugated pipe, thereby allowing adjustment of the bending angle of the elbow.
- a nozzle may be included, wherein the nozzle includes a spray head and a nozzle core accommodated in the spray head, wherein the spray head is integrally formed on the casing.
- the nozzle includes an elbow and a nozzle core, one end of the elbow is connected to the front end of the spray drug delivery device, a boss is formed in the other end of the elbow, and the nozzle core is sleeved onto the boss from the other end of the elbow .
- the elbow is preferably rotatable relative to the sleeve, thereby allowing the angle of the nozzle to be adjusted relative to the sleeve.
- the elbow can be a corrugated pipe, so as to facilitate the rotation of the elbow relative to the casing.
- the angle of the nozzle is fixed relative to the bushing is also within the scope of the present invention, for example, the angle of the nozzle relative to the bushing can be fixed by a matching structure of a cutout and a tab.
- an observation part is formed on the sleeve, and the syringe can be seen through the observation part.
- the observation part can facilitate the user to control the amount of medical solution pushed.
- the observation part is a hollow part or a transparent part formed on the sleeve.
- the nozzle includes a spray head, and an air suction channel is formed on the spray head.
- the inspiratory channel allows the user to draw in air while applying the liquid medicine, thereby facilitating deeper application of the liquid medicine.
- the inhalation channel can also make the user breathe smoothly.
- the air suction channel is formed by at least one of the following structures: an air suction port and an air suction groove.
- a spray drug delivery system which comprises the above-mentioned spray drug delivery device and a syringe, and the syringe can be inserted into the inner cavity of the sleeve of the spray drug delivery device.
- a limit clip is also included, and the limit clip is detachably installed on the plunger of the syringe.
- Fig. 1 shows a perspective view of a spray drug delivery device and a syringe used with it according to a first embodiment of the present invention.
- Figure 2 shows a top view of the spray delivery device and syringe shown in Figure 1 .
- Figure 3 schematically shows the process of inserting the syringe into the spray delivery device.
- Fig. 4 is a sectional view taken along line A-A in Fig. 2 .
- Fig. 5 is a sectional view taken along line B-B in Fig. 2 .
- Fig. 6a is an exploded perspective view of the spray delivery device in Fig. 1 .
- Figure 6b shows a perspective view of a modified sleeve.
- Fig. 6c shows a perspective view of an elbow of a modified structure cooperating with the bushing of Fig. 6b.
- Fig. 7 shows a perspective view of a spray drug delivery device and a syringe used with it according to a second embodiment of the present invention.
- Fig. 8 is a cross-sectional view of the spray delivery device and syringe shown in Fig. 7 .
- Fig. 9 shows a perspective view of a spray drug delivery device and a syringe of a modified structure of the second embodiment.
- Fig. 10 schematically shows the action mode of the spray drug delivery device and the syringe when the limit clip is installed.
- Fig. 11 shows a perspective view of the limit clip.
- Fig. 12 shows a perspective view of a spray drug delivery device and a syringe used with it according to a third embodiment of the present invention.
- FIG. 13 shows an exploded side view of the spray delivery device of FIG. 12 .
- Fig. 14 shows a perspective view of a spray drug delivery device and a syringe used with it according to a fourth embodiment of the present invention.
- Fig. 15 shows a partially exploded perspective view of the spray delivery device and syringe shown in Fig. 14 .
- FIG. 16 shows a cutaway view of the spray delivery device in FIG. 14 .
- Fig. 17 shows a perspective view of a spray drug delivery device according to a fifth embodiment of the present invention.
- Fig. 18 shows a perspective view of a spray drug delivery device according to a sixth embodiment of the present invention.
- FIG. 19 shows an exploded perspective view of the spray delivery device of FIG. 18 .
- FIG. 20 shows a cross-sectional view of the nozzle in FIG. 18 .
- Fig. 21 shows a perspective view of a spray drug delivery device according to a seventh embodiment of the present invention.
- Fig. 22a shows a cross-sectional view of the showerhead in Fig. 21 .
- Fig. 22b shows a perspective view of the showerhead in Fig. 21 .
- Fig. 23 shows a perspective view of a modified structure of the spray drug delivery device shown in Fig. 21 .
- Fig. 24a shows a cross-sectional view of the showerhead in Fig. 23 .
- FIG. 24b shows a perspective view of the showerhead in FIG. 23 .
- Fig. 25 shows a perspective view of another modified structure of the spray drug delivery device shown in Fig. 21 .
- Fig. 26a shows a cross-sectional view of the showerhead in Fig. 25 .
- FIG. 26b shows a perspective view of the showerhead in FIG. 25 .
- front refers to the side away from the user
- rear refers to the side close to the user
- FIG. 1 to 6 show a spray delivery device 110 and a syringe 120 used with the spray delivery device 110 according to a first embodiment of the present invention.
- FIG. 2 shows a top view of the spray delivery device 110 and syringe 120 assembly.
- the spray delivery device 110 comprises a cannula 111 into which a barrel 121 of a syringe 120 can be inserted, as schematically shown in FIG. 3 .
- FIG. 4 and 5 show cross-sectional views taken along lines A-A and B-B in FIG. 2, respectively.
- a nozzle core 131 through which the medical solution from the syringe 120 is atomized is provided inside the nozzle 130 .
- FIG. 6 a shows an exploded perspective view of the spray delivery device 110 to better show the structure of the spray delivery device 110 . It can be seen that a finger press plate 112 is formed at or near the rear end of the sleeve 111 of the spray delivery device 110 .
- the user pushes the plunger 122 of the syringe 120 with the thumb to push the medical solution in the syringe 120 the user's index finger and middle finger can buckle the finger pressing plate 112 .
- a hollow part 113 is formed on the sleeve 111, and the setting of the hollow part 113 enables the user to see the scale on the syringe 121 of the syringe 120 which is set in the sleeve 111, thereby helping the user Control the amount of liquid medicine pushed.
- a transparent material may also be used to form a part of the spray delivery device 110 , or the spray delivery device 110 is entirely made of a transparent material, such as a transparent plastic material, and the like.
- the finger press plate 112 can adopt various suitable shapes, such as polygonal, circular, etc., all of which are within the scope of the present invention.
- Two nozzles 130 are provided on the front end of the sleeve 111 .
- side openings 114 are respectively formed on the left and right sides of the front end of the sleeve 111 , that is, two side openings 114 are formed on the front end.
- the opening direction of the side opening 114 is at an angle to the axial direction of the casing 111 , preferably perpendicular to the axial direction.
- An elbow 132 of a nozzle 130 is connected to each side opening 114 .
- a protruding ring structure is formed on the side opening 114
- a groove structure is formed on the inner surface of the elbow 132 near the side opening 114 .
- the nozzle 130 when assembled, is arranged with its longitudinal axis at an angle relative to the longitudinal axis of the sleeve 111, or that the two longitudinal axes are not aligned. Also, the snap fit between the collar structure and the groove structure allows the elbow 132 to rotate relative to the sleeve 111 to adjust the angle that the longitudinal axis of the nozzle 130 makes with respect to the longitudinal axis of the sleeve 111 .
- connection between the elbow 132 and the side opening 114 can also be connected in other ways, such as intermeshing with threaded structures, and the like.
- the rotation of the elbow 132 relative to the sleeve 111 can also be realized through other additional or alternative structures, such as will be described in the following embodiments.
- the elbow 132 and the side opening 114 may also be non-rotatably fixed to each other.
- a notch 134 is formed at the position of the side opening 114, and a protruding piece 135 is formed on an end connected to the side opening 114 of the elbow 132.
- Tab 135 fits into notch 134 when 132 is attached to side opening 114 .
- the elbow 132 cannot rotate, so that the angle of the elbow 132 relative to the sleeve 111 is fixed.
- the locations of the notch 134 and the protruding piece 135 can also be interchanged, that is, the notch 134 can be formed on the elbow 132 , while the protruding piece 135 can be formed at the corresponding position of the side opening 114 .
- the user first extracts the medicinal solution from the medicine bottle with the syringe 120 . Then, the needle of the syringe 120 is removed, and the barrel 121 of the syringe 120 is inserted into the lumen of the cannula 111 . Then, the user pushes the plunger 122 of the syringe 120 to push the medical solution in the syringe 121 into the nozzle 130 , where the medical solution is atomized.
- the liquid medicine atomized through the nozzle 130 is sprayed from the spray head 133 of the nozzle 130, and can be applied to the patient's nasal cavity, oral cavity and other parts.
- the user pushes the plunger 122 (for example, with the thumb) on the one hand, and buckles the finger pressing plate 112 on the sleeve 111 (for example, with the index finger and middle finger) on the other hand.
- the syringe 120 is kept against the spray drug delivery device 110, thereby reducing or even eliminating the leakage of the drug solution between the spray drug delivery device 110 and the syringe 120, and the spray drug delivery device 110 It will not be sprayed away due to the pressure of the liquid medicine being pushed out.
- the spray delivery device 110 of the first embodiment shown has two nozzles 130 and is therefore particularly suitable for nasal delivery. That is, when administering medicine, the two nozzles 130 may be aimed at the two nostrils of the patient, respectively.
- the two nozzles 130 can be made substantially the same. In this way, when the plunger 122 is pushed, the two nozzles 130 can be supplied with chemical liquid and generate atomized chemical liquid at the same time, and the sprayed atomized chemical liquid can remain substantially the same.
- the syringe 120 will be in a frontal orientation when the two nozzles 130 are aligned and inserted into the patient's nostrils. A low-back-high stance. In this way, when administering medicine, the liquid medicine will be concentrated at the front end of the syringe 120 , and there will be a certain amount of gas between the liquid medicine and the front end of the plunger 122 .
- the gas between the front end of the plunger 122 and the liquid medicine will be compressed, and the compressed gas will generate an additional driving force on the liquid medicine, thereby helping to push out the liquid medicine more quickly.
- the compressed air will be pushed out, and during the process of being pushed out, the pressure of the compressed air can push out the liquid medicine remaining in the spray drug delivery device 110, the syringe 120 and the nozzle 130, thereby realizing The complete spraying of liquid medicine is clean.
- FIG. 7 to 11 show the structure of the assembly of the nebulizer drug delivery device 210 and the syringe 220 according to the second embodiment of the present invention and its modified structure.
- the same or corresponding features as those of the first embodiment are denoted by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first embodiment, without further detailed description of the same features .
- the features described in the first embodiment are also applicable to the second embodiment.
- the spray delivery device 210 used with the syringe 220 has a single nozzle 230 .
- the longitudinal axis of the nozzle 230 is substantially consistent with the longitudinal axis of the spray drug delivery device 210 , or is in a straight line.
- the nozzle 230 includes a head 233 and a nozzle core 231 accommodated in the head 233 .
- the spray head 233 can be integrally formed with the sleeve 211 of the spray delivery device 210 .
- the spray head 233 can also be formed separately from the casing 211 and then installed together.
- a finger-press buckle 212 is formed at the rear end of the sleeve 211, and when pushing the medical solution in the syringe 220, the user can push the plunger 222 of the syringe 220 and buckle the finger-press buckle at the same time. Plate 212, thereby holding spray delivery device 210 and syringe 220 together.
- FIG. 9 to 11 show schematic diagrams of a modified structure of the second embodiment of the present invention.
- a limit clip 240 is installed on the syringe 220 for assisting in metering the amount of liquid medicine sprayed out.
- the limiting clip 240 is installed on the plunger 222 .
- FIG. 11 shows an exemplary structure of the limiting clip 240 .
- the length of the plunger 222 is H1 longer than the length of the stop clip 240 , so that the plunger 222 is allowed to be pushed toward the front end.
- the limit clip 240 will be stuck between the syringe 221 and the plunger 222 , and the limit clip 240 prevents the plunger 222 from being pushed forward further.
- the drug delivery to one nasal cavity is completed.
- remove the limit clip 240 so that the plunger 122 can be continuously pushed toward the front end until the medicinal liquid is exhausted, such as pushing the plunger 222 toward the front end as shown in FIG. Push forward the distance H2 to exhaust the medicinal liquid.
- the setting of the limit clip 240 will help to distribute the medical solution in the syringe 220 to ensure that the amount of the medical solution delivered to the two nasal cavities is substantially equal.
- Figures 12 and 13 show a spray delivery device 310 and a syringe 320 for use therewith in accordance with a third embodiment of the present invention.
- the same or corresponding features as those of the first and second embodiments are denoted by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first and second embodiments, without referring to the same characteristics are described in detail. Unless stated to the contrary, the features described in the first and second embodiments are also applicable to the third embodiment.
- the spray delivery device 310 in the third embodiment can be used with a syringe 320 and has a single nozzle 330 at the front end of the spray delivery device 310 .
- the axis direction of the nozzle 330 of the spray drug delivery device 310 of the third embodiment is at an angle to the axis direction of the spray drug delivery device 310 main body (ie, its sleeve), as shown in FIG. 13 of.
- the nozzle 330 also includes a nozzle core 331 , an elbow 332 accommodating the nozzle core 331 and connected to the main body of the spray drug delivery device 310 , and a spray head 333 sleeved on the nozzle core 331 and the elbow 332 .
- FIG. 14 to 16 show a fourth embodiment of a spray delivery device 410 of the present invention and a syringe 420 for use therewith.
- the same or corresponding feature parts as those of the first to third embodiments are denoted by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first to third embodiments, without referring to the same characteristics are described in detail. Unless otherwise stated, the features described in the first to third embodiments are also applicable to the fourth embodiment.
- the spray drug delivery device 410 includes two nozzles 430, each of which includes a nozzle body 432, and the nozzle body 432 is integrally formed with the spray drug delivery device 410, as can be seen from FIG. It can be seen more clearly in the cross-sectional view shown.
- the nozzle body 432 of the nozzle 430 is arc-shaped as a whole, so as to facilitate manufacture.
- the nozzle 430 also includes a nozzle core 431 inserted into the nozzle body 432 .
- the structure of the integrally formed nozzle 430 helps to simplify the structure and reduce the number of parts.
- Fig. 17 shows a spray drug delivery device 510 according to a fifth embodiment of the present invention.
- the same or corresponding feature parts as those of the first to fourth embodiments are indicated by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first to fourth embodiments, without referring to the same characteristics are described in detail. Unless otherwise stated, the features described in the first to fourth embodiments are also applicable to the fifth embodiment.
- the nozzle 530 includes a bellows 532 to serve as a nozzle body of the nozzle 530, and the bellows 532 is connected to the body of the spray drug delivery device 510.
- corrugated tube 532 as the body of the nozzle 530 can facilitate molding.
- the corrugated tube 532 can be made straight during molding, and can be bent to a desired curvature when used.
- the bellows 532 can also adjust its bending angle, so that it can be applied to various applications.
- the spray drug delivery device 610 includes a sleeve 611 as its main body, a finger pressing plate 612 is formed at the rear end of the sleeve 611 , and a nozzle 630 is installed at the front end of the sleeve 611 . Similar to the first embodiment, the nozzle 630 can be connected to the sleeve 611 by means such as a snap ring-groove fit (as shown in the figures), threaded connection or the like.
- a nozzle 630 includes an elbow 632 and a nozzle core 631 inserted in the elbow 632 .
- 20 shows a cross-sectional view of the nozzle 630, which shows that a boss 633 is formed in the elbow 632, and the nozzle core 631 inserted in the elbow 632 can be sleeved on the boss 633, so that the nozzle core 631 is Fixation of elbow 632.
- the nozzle 630 with the above structure can be applied to the spray drug delivery devices of the first to fifth embodiments described above.
- Figures 21 to 26b show a spray drug delivery device 710 of the seventh embodiment of the present invention and its variants.
- the same or corresponding feature parts as those of the first to sixth embodiments are indicated by the same or similar reference numerals, and the following disclosure mainly describes the features different from those of the first to sixth embodiments, without referring to the same characteristics are described in detail. Unless otherwise stated, the features described in the first to sixth embodiments are also applicable to the seventh embodiment.
- the spray drug delivery device 710 of the seventh embodiment at least one, preferably a plurality of suction ports 734 are formed on the spray head 733 of the nozzle.
- the suction port 734 is arranged around the circumference of the spray head 733 .
- the suction port 734 is generally rectangular.
- the inhalation port 734 By providing the inhalation port 734, when the spray drug delivery device 710 is used to administer medicine to the user's nasal cavity, the inhalation port 734 provides a passage for inhaling air.
- the inhaled air helps to bring the atomized medicinal solution deep into the nasal cavity, which in turn facilitates the absorption of the medicinal solution by the nasal mucosa.
- the setting of the suction port 734 can also keep the user's breathing smooth during the administration process, which is especially useful for children and the like.
- FIG. 23-24b show a modified structure of the spray drug delivery device 710 of the seventh embodiment. Wherein, several circular suction ports 734' are provided on the shower head 733'.
- 25-26b show another modified structure of the spray drug delivery device 710 of the seventh embodiment.
- a plurality of suction grooves 734" are formed on the outer peripheral surface of the spray head 733". These suction slots 734" extend from the front end to the rear end of the spray head 733". These inhalation slots 734" can form a pathway for inhaling air when administering a drug to the user's nasal cavity.
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Abstract
Description
Claims (15)
- 一种喷雾给药装置,其特征在于,所述喷雾给药装置包括:套管,所述套管形成有内腔,所述内腔能够容纳注射器的针筒;以及至少一个喷嘴,所述喷嘴设置在所述套管的前端,并且与所述套管的所述内腔连通;其中,所述至少一个喷嘴的轴线方向相对于所述套管的轴线方向成角度。
- 一种喷雾给药装置,其特征在于,所述喷雾给药装置包括:套管,所述套管形成有内腔,所述内腔能够容纳注射器的针筒;至少一个喷嘴,所述喷嘴设置在所述套管的前端,并且与所述套管的所述内腔连通;以及指压扣板,所述指压扣板形成在所述套管的后端或邻近所述后端。
- 一种喷雾给药装置,其特征在于,所述喷雾给药装置包括:套管,所述套管形成有内腔,所述内腔能够容纳注射器的针筒;以及两个喷嘴,所述两个喷嘴设置在所述套管的前端,并分别位于所述套管的所述前端的左右两侧,并且所述两个喷嘴与所述套管的所述内腔连通。
- 如权利要求1~3中任一项所述的喷雾给药装置,其特征在于,所述喷嘴包括弯管,所述弯管的一端连接在所述喷雾给药装置的所述前端,所述弯管的另一端中插入有喷嘴芯,并且喷头套设在所述弯管的所述另一端上。
- 如权利要求4所述的喷雾给药装置,其特征在于,所述喷嘴能够相对于所述套管转动。
- 如权利要求5所述的喷雾给药装置,其特征在于,所述弯管为波纹管。
- 如权利要求1或2所述的喷雾给药装置,其特征在于,包括一个所述喷嘴,其中,所述喷嘴包括喷头和容纳在所述喷头中的喷嘴芯,其中,所述喷头一体形成于所述套管上。
- 如权利要求1~3中任一项所述的喷雾给药装置,其特征在于,所述喷嘴包括弯管和喷嘴芯,所述弯管的一端连接在所述喷雾给药装置的所述前端,所述弯管的另一端中形成有凸柱,所述喷嘴芯从所述弯管的所述另一端套设到所述凸柱上。
- 如权利要求8所述的喷雾给药装置,其特征在于,所述弯管为波纹管。
- 如权利要求1~3中任一项所述的喷雾给药装置,其特征在于,所述套管上形成有观察部,透过所述观察部能够看到所述注射器。
- 如权利要求10所述的喷雾给药装置,其特征在于,所述观察部为形成在所述套管上的镂空部或者透明部分。
- 如权利要求1~3中任一项所述的喷雾给药装置,其特征在于,所述喷嘴包括喷头,所述喷头上形成有吸气通道。
- 如权利要求12所述的喷雾给药装置,其特征在于,所述吸气通道由以下结构中的至少一种形成:吸气口和吸气槽。
- 一种喷雾给药系统,其特征在于,所述喷雾给药系统包括:如权利要求1~13中任一项所述的喷雾给药装置;以及注射器,所述注射器能够插入到所述喷雾给药装置的所述套管的内腔中。
- 如权利要求14所述的喷雾给药系统,其特征在于,还包括限位卡子,所述限位卡子可拆卸地安装在所述注射器的柱塞上。
Priority Applications (3)
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EP22841485.0A EP4371594A1 (en) | 2021-07-16 | 2022-07-15 | Spray drug administration apparatus and spray drug administration system comprising said apparatus |
MX2024000798A MX2024000798A (es) | 2021-07-16 | 2022-07-15 | Aparato para administrar farmacos por atomizacion y sistema para administrar farmacos por atomizacion que comprende dicho aparato. |
JP2024502211A JP2024523743A (ja) | 2021-07-16 | 2022-07-15 | 噴霧薬物投与装置及びそれを備える噴霧薬物投与システム |
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CN202110805974.7A CN113350634A (zh) | 2021-07-16 | 2021-07-16 | 喷雾给药装置和包括该装置的喷雾给药系统 |
CN202110805974.7 | 2021-07-16 |
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WO2023284852A1 true WO2023284852A1 (zh) | 2023-01-19 |
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JP (1) | JP2024523743A (zh) |
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CN113350634A (zh) * | 2021-07-16 | 2021-09-07 | 丁要武 | 喷雾给药装置和包括该装置的喷雾给药系统 |
CN113893418B (zh) * | 2021-12-02 | 2022-07-12 | 时新(上海)产品设计有限公司 | 喷剂装置 |
WO2023192691A2 (en) * | 2022-04-01 | 2023-10-05 | Wake Forest University Health Sciences | Methods and formulations for intranasal delivery of insulin in the treatment of diabetic eye disease |
CN115445062B (zh) * | 2022-09-16 | 2023-12-05 | 南阳市口腔医院 | 一种医用鼻腔给药装置 |
CN117504070A (zh) * | 2022-09-23 | 2024-02-06 | 天舟医疗(苏州)有限公司 | 鼻腔喷雾给药装置及包括该装置的喷雾系统 |
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-
2021
- 2021-07-16 CN CN202110805974.7A patent/CN113350634A/zh active Pending
-
2022
- 2022-07-15 MX MX2024000798A patent/MX2024000798A/es unknown
- 2022-07-15 WO PCT/CN2022/105940 patent/WO2023284852A1/zh active Application Filing
- 2022-07-15 EP EP22841485.0A patent/EP4371594A1/en active Pending
- 2022-07-15 JP JP2024502211A patent/JP2024523743A/ja active Pending
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JP2024523743A (ja) | 2024-06-28 |
MX2024000798A (es) | 2024-04-09 |
CN113350634A (zh) | 2021-09-07 |
EP4371594A1 (en) | 2024-05-22 |
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