WO2023216767A1 - 一种用于颗粒脂肪纯化的双层注射器装置 - Google Patents

一种用于颗粒脂肪纯化的双层注射器装置 Download PDF

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Publication number
WO2023216767A1
WO2023216767A1 PCT/CN2023/085908 CN2023085908W WO2023216767A1 WO 2023216767 A1 WO2023216767 A1 WO 2023216767A1 CN 2023085908 W CN2023085908 W CN 2023085908W WO 2023216767 A1 WO2023216767 A1 WO 2023216767A1
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syringe
port
external
internal
piston
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PCT/CN2023/085908
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English (en)
French (fr)
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张梅
刘永霞
宋武
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北京万洁天元医疗器械股份有限公司
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Publication of WO2023216767A1 publication Critical patent/WO2023216767A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles

Definitions

  • the present application relates to the technical field of medical devices, and in particular to a double-layer syringe device for purification of particulate fat.
  • Autologous adipose tissue has been used as a potential filling material for soft tissue defects.
  • Autologous fat has obvious advantages as a soft tissue transplant material. It has good biocompatibility, no rejection reaction, abundant sources, simpler surgery, less trauma, faster recovery, and the postoperative transplantation area is soft and natural; it also has the effect of shaping and slimming. .
  • autologous fat has been widely used in clinical practice.
  • the main indications for autologous fat cell injection and transplantation are: (1) Body surface soft tissue defects or depressed deformities, such as congenital diseases, such as hemifacial atrophy, hemifacial shortness, etc.; traumatic injuries, Such as soft tissue depression and deformity after various types of trauma, scar depression, contour deformity, etc.; iatrogenic injuries, such as defect and deformity after tumor surgery, soft tissue atrophy and deformity after isotope radiotherapy for hemangioma, local depression and deformity after dilator surgery, various surgical operations The local soft tissue depression after surgery (the depression after liposuction, etc.).
  • contour reshaping such as rhinoplasty, chin augmentation, temporal augmentation, forehead augmentation, cheek augmentation, breast augmentation, buttock augmentation, etc.
  • rejuvenation treatments such as facial volume supplement, back of hand volume supplement, etc.
  • Yes Limit necessary indications such as rhinoplasty, chin augmentation, temporal augmentation, forehead augmentation, cheek augmentation, breast augmentation, buttock augmentation, etc.
  • Adipose tissue occupies a very important position in the field of tissue engineering. in the research and exploration stage. With the further development of science, technology and research, it is believed that autologous fat will become a superior weapon in the field of medical treatment and regeneration.
  • Adipose tissue aspirated from the human body can be purified by centrifugation or standing.
  • the application of granular fat needs to effectively remove impurities and avoid contamination during the application process.
  • centrifuge tubes are used clinically to centrifuge the extracted fat tissue. After centrifugation, it is put into an open device and the purified granular fat is extracted with a syringe. For injection or other operations, the operation is very cumbersome and the possibility of contamination is very high.
  • the purpose of this application is to provide a double-layer syringe device for particulate fat purification, including an outer syringe and an inner syringe connected to the outer syringe through the open end of the outer syringe push rod, which can be centrifuged or static.
  • Method The extracted adipose tissue is purified, and it is easy to separate after purification to prevent contamination of the purified tissue.
  • a double-layer syringe device for granular fat purification including an external syringe and an internal syringe.
  • the external syringe includes an outer tube, an external syringe push rod and an external syringe piston arranged in the outer tube.
  • the external syringe push rod is a hollow structure.
  • the external syringe piston is arranged at the top of the external syringe push rod, the outer peripheral surface of the external syringe piston is in contact with the inner wall of the outer tube, the external syringe push rod and the external syringe piston are respectively provided with open ends;
  • the inner syringe includes an inner tube disposed within the outer syringe push rod.
  • the inner tube is provided with a second port at its top end, and the second port is detachably connected to the open end of the outer syringe push rod.
  • the outer syringe piston can reciprocate within the outer tube.
  • the internal syringe is detachably sleeved with the external syringe push rod through the second port, and the two injection chambers of the outer tube and the inner tube are connected through the external syringe piston and the open end of the external syringe push rod, so that the external syringe and the internal syringe Form a through cavity.
  • the inner syringe further includes an inner syringe core rod and an inner syringe piston disposed in the inner tube.
  • the inner syringe piston is disposed at the top of the inner syringe core rod.
  • the outer peripheral surface of the inner syringe piston is in contact with the inner wall of the inner tube. Abut.
  • the internal syringe piston can reciprocate within the inner tube.
  • the external syringe push rod and the external syringe piston, the internal syringe core rod and the internal syringe piston, the external syringe and the internal syringe are all in a concentric relationship and share a common central longitudinal axis.
  • the open end of the external syringe push rod is provided with an inwardly extending external syringe piston mechanism connection portion, and the second port is detachably connected to the external syringe piston mechanism connection portion.
  • the connecting portion of the external syringe piston mechanism has an open structure and can be tightly connected to the second port, thereby realizing the interconnected connection between the inner tube of the internal syringe and the outer tube of the external syringe.
  • a first port is provided at the top of the outer tube, and a sealing cap is detachably connected to the first port.
  • the sealing cap cooperates with the first port to achieve the effect of sealing the entire double-layer syringe device, forming a unique closed centrifugal device.
  • the second port is provided with an outwardly protruding second port extension
  • the second port extension is a hollow protruding locking joint and the inner wall of the second port extension is provided with internal threads
  • the connecting portion of the external syringe piston mechanism is provided with external threads and is screwed and fixed with the internal threads of the second port extension.
  • the locking joint of the second port extension can effectively seal the inner tube and prevent liquid leakage during centrifugation or standing.
  • the first port is provided with an outwardly protruding first port extension
  • the first port extension is a hollow protruding locking joint and the inner wall of the first port extension is provided with internal threads
  • the sealing cap An external thread is provided inside and is screwed and fixed with the internal thread of the first port extension.
  • the locking joint on the extension of the first port can effectively seal the outer tube and prevent liquid leakage during centrifugation or standing.
  • the rear end of the inner syringe rod is provided with an inner syringe rod holding portion, and the inner syringe rod holding portion is a cylindrical structure.
  • the internal syringe stem holding portion can also be of other structures, depending on the needs of the user.
  • the outer syringe piston and the inner syringe piston are rubber pistons.
  • the outer syringe piston and the inner syringe piston are detachably connected to the outer syringe push rod and the inner syringe core rod, and the selected rubber piston has the advantage of low cost.
  • the locking joints of the first port extension and the second port extension are internal conical joints, and the outer sleeve has a threaded locking joint.
  • the second port extension is an injection needle hole seat.
  • the injection needle needle hole seat of the second port extension can be locked with the connection part of the external syringe piston mechanism, and the external syringe push rod can also be arbitrarily interconnected with the syringe with a matching needle tube connection part on the top to realize the transfer and application of purified granular fat. .
  • the remaining material in the outer tube of the outer syringe is Purified granular fat, swelling fluid and other substances, and then separate the second port of the inner tube from the connection part of the external syringe piston mechanism to separate the internal syringe from the external syringe, using a syringe with a matching needle tube connection part at the top and an external syringe piston
  • the connecting part of the mechanism is connected to extract the purified granular fat, and the purified granular fat is transferred and applied.
  • the double-layer syringe device used for granular fat purification in this application adopts the above technical solution, including an external syringe, an internal syringe and a sealing cap. Pistons and push rods are provided inside both the external syringe and the internal syringe.
  • the external syringe Both the piston and the external syringe push rod have an open end.
  • the internal syringe is detachably connected to the open end through the second port and communicates with the external syringe through the open end.
  • the external syringe is connected to the cap, forming a unique closed centrifugal device.
  • Figure 1 shows a schematic diagram of the overall structure of a double-layer syringe device used for particulate fat purification in this application.
  • Figure 2 shows a schematic diagram of the internal structure of a double-layer syringe device used for particulate fat purification in this application.
  • Figure 3 shows a schematic structural diagram of an external syringe push rod of a double-layer syringe device used for particulate fat purification in this application.
  • Figure 4 shows a schematic diagram of the inner tube structure of a double-layer syringe device used for particulate fat purification in this application.
  • spatially relative terms such as “below”, “below”, “lower”, “upper”, “upper”, etc., may be used to describe the relationship between one element or feature and another. The relationship of elements or features in the drawing. It will be understood that the spatially relative terms are intended to encompass different orientations of the item in use or operation in addition to the orientation depicted in the figures. For example, if the object in the figures is turned over, elements described as “below” or “beneath” other elements or features would then be oriented “above” the elements or features. Therefore, the exemplary term “below” may include both lower and upper directions. The object may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative terms used herein should be interpreted accordingly.
  • a double-layer syringe device for particulate fat purification includes an external syringe 1 and an internal syringe 2.
  • the external syringe 1 includes an outer tube 4 and an external syringe pusher arranged in the outer tube 4.
  • the external syringe push rod 6 is a hollow structure.
  • the external syringe piston 8 is provided at the top of the external syringe push rod 6.
  • the outer peripheral surface of the external syringe piston 8 is in contact with the inner wall of the outer tube 4.
  • the outer syringe push rod 6 and the outer syringe piston 8 are respectively provided with open ends;
  • the inner syringe 2 includes an inner tube 5 arranged in the outer syringe push rod 6, and the top end of the inner tube 5 is provided with an open end.
  • the second port 13 is detachably connected to the open end of the external syringe push rod 6 .
  • the materials of the outer tube 4 and the inner tube 5 can be selected from plastic or glass.
  • the external syringe piston 8 can reciprocate within the outer tube 4 .
  • the inner syringe 2 is detachably sleeved with the outer syringe push rod 6 through the second port 13, and connects the two injection chambers of the outer tube 4 and the inner tube 5 through the outer syringe piston 8 and the open end of the outer syringe push rod 6 , so that the outer syringe 1 and the inner syringe 2 form a through cavity.
  • the internal syringe 2 also includes an internal syringe core rod 7 and an internal syringe piston 9 arranged in the inner tube 5.
  • the internal syringe piston 9 is arranged at the top end of the internal syringe core rod 7.
  • the outer peripheral surface of the internal syringe piston 9 It is in contact with the inner wall of the inner tube 5 .
  • the rear end of the inner syringe core rod 7 is provided with an inner syringe core rod holding portion 11, and the inner syringe core rod holding portion 11 is a cylindrical structure.
  • the inner syringe core rod holding part 11 can also be other The structure is determined according to the needs of the user.
  • the internal syringe piston 9 is reciprocally movable within the inner tube 5 .
  • the external syringe push rod 6 and the external syringe piston 8, the internal syringe core rod 7 and the internal syringe piston 9, the external syringe 1 and the internal syringe 2 are all in a concentric relationship and share a common central longitudinal axis.
  • the outer syringe piston 8 and the inner syringe piston 9 are rubber pistons.
  • the outer syringe piston 8 and the inner syringe piston 9 are detachably connected to the outer syringe push rod 6 and the inner syringe core rod 7, and the selected rubber piston has the advantage of low cost.
  • the open end of the external syringe push rod 6 is provided with an external syringe piston mechanism connecting portion 12 extending inward, and the second port 13 is detachably connected to the external syringe piston mechanism connecting portion 12 .
  • the external syringe piston mechanism connecting portion 12 has an open structure and can be tightly connected to the second port 13, thereby realizing the interconnected connection between the inner tube 5 of the internal syringe 2 and the outer tube 4 of the external syringe 1.
  • the second port 13 is provided with an outwardly protruding second port extension.
  • the second port extension is a hollow protruding locking joint and the inner wall of the second port extension is provided with internal threads.
  • the external syringe The piston mechanism connecting part 12 is provided with external threads and is screwed and fixed with the internal threads of the second port extension part.
  • the locking joint of the second port extension can achieve a good sealing of the inner tube 5 and prevent liquid leakage during centrifugation or standing.
  • a first port 10 is provided at the top of the outer tube 4, and a sealing cap 3 is detachably connected to the first port 10.
  • the sealing cap 3 cooperates with the first port 10 to achieve the effect of sealing the entire double-layer syringe device, forming a unique closed centrifugal device.
  • the first port 10 is provided with an outwardly protruding first port extension.
  • the first port extension is a hollow protruding locking joint and the inner wall of the first port extension is provided with internal threads.
  • the inside of the cap 3 An external thread is provided and is screwed and fixed with the internal thread of the first port extension.
  • the locking joint of the first port extension can achieve good sealing of the outer tube 4 and prevent liquid leakage during centrifugation or standing.
  • the locking joints of the first port extension and the second port extension are internal conical joints, and the outer sleeve has a threaded locking joint.
  • the second port extension is an injection needle hole seat.
  • the injection needle needle hole seat of the second port extension can be locked with the external syringe piston mechanism connection part 12, and the external syringe push rod 6 can also be arbitrarily interconnected with the syringe with a matching needle tube connection part on the top to realize the transfer of purified granular fat. and applications.
  • the present application relates to a double-layer syringe device for particulate fat purification.
  • the outer syringe includes an outer tube, an outer syringe push rod and an outer syringe piston disposed in the outer tube.
  • the inner syringe includes an inner tube disposed within the outer syringe push rod.

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Abstract

一种用于颗粒脂肪纯化的双层注射器装置，外部注射器（1）包括外管（4）和设置在外管（4）内的外部注射器推杆（6）和外部注射器活塞（8），外部注射器活塞（8）设置在外部注射器推杆（6）的顶端，外部注射器推杆（6）和外部注射器活塞（8）上分别设有开口端；内部注射器（2）包括设置在外部注射器推杆（6）内的内管（5），内管（5）的顶端设有第二端口（13），第二端口（13）与外部注射器推杆（6）的开口端可拆卸连接。外部注射器活塞（8）和外部注射器推杆（6）均具有开口端，内部注射器（2）的第二端口（13）与该开口端可拆卸连接并通过该开口端和外部注射器（1）连通，外部注射器（1）与封帽（3）连接，形成独特的封闭式离心装置。解决了现有的纯化方式操作繁琐和容易受到污染的问题，从而影响纯化后的颗粒脂肪使用后安全性的技术问题。

Description

一种用于颗粒脂肪纯化的双层注射器装置
交叉引用
本申请要求在中国专利局提交的、申请号为202210508111.8、申请日为2022年05月11日、申请名称为“一种用于颗粒脂肪纯化的双层注射器装置”的中国专利申请的优先权，该申请的全部内容通过引用结合在本申请中。
技术领域
本申请涉及医疗器械技术领域，尤其涉及一种用于颗粒脂肪纯化的双层注射器装置。
背景技术
自体脂肪组织已被用作软组织缺陷的潜在填充材料。自体脂肪作为软组织移植材料优势明显，生物相容性好、无排异反应、来源丰富、手术较简单、创伤较小、恢复较快，术后移植区柔软自然；同时还有塑形瘦身的作用。
近年来自体脂肪在临床得到了广泛应用，自体脂肪细胞注射移植的适应证主要有：(1)体表软组织缺损或凹陷畸形，例如先天性疾病，如半面萎缩、半面短小等；创伤性损伤，如各类外伤后的软组织凹陷畸形、瘢痕凹陷、轮廓畸形等；医源性损伤，如肿瘤术后缺损畸形、血管瘤同位素放疗后软组织萎缩畸形、扩张器术后局部凹陷畸形、各类外科手术后的局部软组织凹陷(脂肪抽吸后的凹陷等)。
(2)美容性治疗，例如轮廓重塑，如隆鼻、隆颏、丰颞、丰额、丰颊、丰乳、丰臀等；年轻化治疗，如面部容积补充、手背容积补充等；有限制必要的适应症。
自体脂肪移植不仅在整形外科领域掀起了一场风波，在其他学科领域也有越来越多的应用，如使用脂肪来封闭硬脑膜、假性脑膨出、治疗慢性溃疡、眼眶脂肪移植填充，在听骨重建假体中加入脂肪也被证实了比标准手术获得更好的听力效果，脂肪中提取的干细胞及活性分子等在再生医学及转化医学都有巨大的前景，一项前瞻性研究中显示，脂肪中提取的再生细胞注射到腋窝是缓解淋巴水肿非常有希望的治疗方法；另外在心脏领域，干细胞可以修复心肌细胞，可以分化为血管生成细胞，释放血管生成分子等。但在这一领域诸多问题尚缺乏大型的动物实验及临床研究，比如脂肪移植机制、移植技术优化、干细胞的多学科应用等。脂肪组织在组织工程领域占有非常重要的地位，目前处 于研究探索阶段。随着科学技术及研究的进一步发展，相信自体脂肪会成为优越的医学治疗和再生领域的武器。
从人体抽吸的脂肪组织可以通过离心或静置的方式进行纯化。颗粒脂肪的应用需要有效的去除杂质，并在应用的过程中避免污染，目前临床上采用离心管对抽取的脂肪组织进行离心，离心后装入敞口的装置中用注射器抽取纯化后的颗粒脂肪用于注射或其他操作，操作起来非常繁琐，并且受污染的可能性非常大。
因此，需要提供一种用于颗粒脂肪纯化的双层注射器装置，用以解决现有的纯化方式操作繁琐和容易受到污染的缺点，从而解决纯化后的颗粒脂肪使用后安全性的技术问题。
发明内容
有鉴于此，本申请的目的在于提供一种用于颗粒脂肪纯化的双层注射器装置，包括外部注射器以及通过外部注射器推杆的开口端与外部注射器连通的内部注射器，可以采用离心或静置的方法对抽取的脂肪组织进行纯化，且纯化后易于分离，防止对纯化后的组织产生污染。
为解决以上技术问题，本申请采用下述技术方案：
一种用于颗粒脂肪纯化的双层注射器装置，包括外部注射器和内部注射器，所述外部注射器包括外管和设置在外管内的外部注射器推杆和外部注射器活塞，所述外部注射器推杆为中空结构，所述外部注射器活塞设置在外部注射器推杆的顶端，所述外部注射器活塞的外周面与外管的内壁抵接，所述外部注射器推杆和外部注射器活塞上分别设有开口端；所述内部注射器包括设置在外部注射器推杆内的内管，所述内管的顶端设有第二端口，所述第二端口与外部注射器推杆的开口端可拆卸连接。所述外部注射器活塞可在外管内往复运动。内部注射器通过第二端口与外部注射器推杆可拆卸地套设在一起，并通过外部注射器活塞和外部注射器推杆的开口端将外管和内管两个注射腔连接，使外部注射器和内部注射器形成一个贯通腔体。
优选地，所述内部注射器还包括设置在内管内的内部注射器芯杆和内部注射器活塞，所述内部注射器活塞设置在内部注射器芯杆的顶端，所述内部注射器活塞的外周面与内管的内壁抵接。所述内部注射器活塞可在内管内往复运动。所述外部注射器推杆和外部注射器活塞、内部注射器芯杆和内部注射器活塞、外部注射器和内部注射器均为同心关系，有着共同的中心纵向轴。
优选地，所述外部注射器推杆的开口端设有向内延伸的外部注射器活塞机构连接部，所述第二端口与外部注射器活塞机构连接部可拆卸连接。所述外部注射器活塞机构连接部为开口结构，可以与第二端口紧密连接，实现了内部注射器的内管和外部注射器的外管互通的连接。
优选地，所述外管的顶端设有第一端口，所述第一端口上可拆卸连接有封帽。所述封帽配合第一端口可实现将整个双层注射器装置密封的效果，形成独特的封闭式离心装置。
优选地，所述第二端口设有向外凸起的第二端口延伸部，所述第二端口延伸部为中空凸起的锁紧接头且第二端口延伸部内壁设有内螺纹，所述外部注射器活塞机构连接部设有外螺纹且与第二端口延伸部的内螺纹螺接固定。第二端口延伸部的锁紧接头可以很好的实现内管的密封，在离心或静置时，不会漏液。
优选地，所述第一端口设有向外凸起的第一端口延伸部，第一端口延伸部为中空凸起的锁紧接头且第一端口延伸部内壁设有内螺纹，所述封帽内部设有外螺纹且与第一端口延伸部的内螺纹螺接固定。第一端口延伸部的锁紧接头可以很好的实现外管的密封，在离心或静置时，不会漏液。
优选地，所述内部注射器芯杆的尾端设有内部注射器芯杆握持部，所述内部注射器芯杆握持部为圆柱形结构。内部注射器芯杆握持部也可以为其他结构，具体根据使用者的需求而定。
优选地，所述外部注射器活塞和内部注射器活塞为橡胶活塞。外部注射器活塞和内部注射器活塞与外部注射器推杆和内部注射器芯杆为可拆卸连接，选用的橡胶活塞具有成本低的优点。
优选地，所述第一端口延伸部和第二端口延伸部的锁紧接头均为内部圆锥接头，外套具有螺纹的锁紧接头。
优选地，所述第二端口延伸部为注射针针孔座。第二端口延伸部的注射针针孔座可以和外部注射器活塞机构连接部配合锁紧，外部注射器推杆也可以和顶部具有配套针管连接部的注射器任意互联，实现纯化的颗粒脂肪的转移和应用。
本申请的一种用于颗粒脂肪纯化的双层注射器装置的使用过程为：
在使用双层注射器装置进行工作时，先握住外部注射器的外管，拉动外部注射器推 杆和外部注射器活塞抽取脂肪组织，脂肪组织通过第一端口进入外管的腔体内，用封帽密封第一端口，将整个装置进行离心或静置，脂肪组织充分分层后拉动内部注射器芯杆和内部注射器活塞，此时，内部注射器的内管内形成另一个放置腔体，通过外部注射器活塞机构连接部将分层后的上层物质吸取到内管中，此时外部注射器的外管中剩下纯化后的颗粒脂肪和肿胀液等物质，然后将内管的第二端口与外部注射器活塞机构连接部分离，实现将内部注射器与外部注射器分离，用顶部具有配套针管连接部的注射器和外部注射器活塞机构连接部连接，抽取纯化后的颗粒脂肪，进行纯化的颗粒脂肪的转移和应用。
本申请的有益效果如下：
本申请的一种用于颗粒脂肪纯化的双层注射器装置由于采用了以上技术方案，包括外部注射器、内部注射器和封帽，在外部注射器和内部注射器的内部均设置有活塞和推杆，外部注射器活塞和外部注射器推杆均具有开口端，内部注射器通过第二端口与该开口端可拆卸连接，并通过该开口端和外部注射器连通，外部注射器与封帽连接，形成独特的封闭式离心装置。本申请解决了现有的纯化方式操作繁琐和容易受到污染的问题，从而影响纯化后的颗粒脂肪使用后安全性的技术问题。
上述说明仅为本申请技术方案的概述，为了能够更清楚地了解本申请的技术手段并可依据说明书的内容予以实施，同时为了使本申请的上述和其他目的、技术特征以及优点更加易懂，以下列举一个或多个优选实施例，并配合附图详细说明如下。
附图说明
一个或多个实施例通过与之对应的附图中的图片进行示例性说明，这些示例性说明并不构成对实施例的限定，附图中具有相同参考数字标号的元件表示为类似的元件，除非有特别申明，附图中的图不构成比例限制。
图1示出本申请的一种用于颗粒脂肪纯化的双层注射器装置的整体结构示意图。
图2示出本申请的一种用于颗粒脂肪纯化的双层注射器装置的内部结构示意图。
图3示出本申请的一种用于颗粒脂肪纯化的双层注射器装置的外部注射器推杆结构示意图。
图4示出本申请的一种用于颗粒脂肪纯化的双层注射器装置的内管结构示意图。
主要附图标记说明：
1-外部注射器，2-内部注射器，3-封帽，4-外管，5-内管，6-外部注射器推杆，7-内 部注射器芯杆，8-外部注射器活塞，9-内部注射器活塞，10-第一端口，11-内部注射器芯杆握持部，12-外部注射器活塞机构连接部，13-第二端口。
具体实施方式
下面结合附图，对本申请的具体实施方式进行详细描述，但应当理解本申请的保护范围并不受具体实施方式的限制。
除非另有其他明确表示，否则在整个说明书和权利要求书中，术语“包括”或其变换如“包含”或“包括有”等等将被理解为包括所陈述的元件或组成部分，而并未排除其他元件或其他组成部分。
在本文中，为了描述的方便，可以使用空间相对术语，诸如“下面”、“下方”、“下”、“上面”、“上方”、“上”等，来描述一个元件或特征与另一元件或特征在附图中的关系。应理解的是，空间相对术语旨在包含除了在图中所绘的方向之外物件在使用或操作中的不同方向。例如，如果在图中的物件被翻转，则被描述为在其他元件或特征“下方”或“下”的元件将取向在所述元件或特征的“上方”。因此，示范性术语“下方”可以包含下方和上方两个方向。物件也可以有其他取向(旋转90度或其他取向)且应对本文使用的空间相对术语作出相应的解释。
如图1-图4所示，一种用于颗粒脂肪纯化的双层注射器装置，包括外部注射器1和内部注射器2，所述外部注射器1包括外管4和设置在外管4内的外部注射器推杆6和外部注射器活塞8，所述外部注射器推杆6为中空结构，所述外部注射器活塞8设置在外部注射器推杆6的顶端，所述外部注射器活塞8的外周面与外管4的内壁抵接，所述外部注射器推杆6和外部注射器活塞8上分别设有开口端；所述内部注射器2包括设置在外部注射器推杆6内的内管5，所述内管5的顶端设有第二端口13，所述第二端口13与外部注射器推杆6的开口端可拆卸连接。外管4和内管5的材料可选择塑料或者玻璃。所述外部注射器活塞8可在外管4内往复运动。内部注射器2通过第二端口13与外部注射器推杆6可拆卸地套设在一起，并通过外部注射器活塞8和外部注射器推杆6的开口端将外管4和内管5两个注射腔连接，使外部注射器1和内部注射器2形成一个贯通腔体。
所述内部注射器2还包括设置在内管5内的内部注射器芯杆7和内部注射器活塞9，所述内部注射器活塞9设置在内部注射器芯杆7的顶端，所述内部注射器活塞9的外周面与内管5的内壁抵接。所述内部注射器芯杆7的尾端设有内部注射器芯杆握持部11，所述内部注射器芯杆握持部11为圆柱形结构。内部注射器芯杆握持部11也可以为其他 结构，具体根据使用者的需求而定。
所述内部注射器活塞9可在内管5内往复运动。所述外部注射器推杆6和外部注射器活塞8、内部注射器芯杆7和内部注射器活塞9、外部注射器1和内部注射器2均为同心关系，有着共同的中心纵向轴。
所述外部注射器活塞8和内部注射器活塞9为橡胶活塞。外部注射器活塞8和内部注射器活塞9与外部注射器推杆6和内部注射器芯杆7为可拆卸连接，选用的橡胶活塞具有成本低的优点。
所述外部注射器推杆6的开口端设有向内延伸的外部注射器活塞机构连接部12，所述第二端口13与外部注射器活塞机构连接部12可拆卸连接。所述外部注射器活塞机构连接部12为开口结构，可以与第二端口13紧密连接，实现了内部注射器2的内管5和外部注射器1的外管4互通的连接。
所述第二端口13设有向外凸起的第二端口延伸部，所述第二端口延伸部为中空凸起的锁紧接头且第二端口延伸部内壁设有内螺纹，所述外部注射器活塞机构连接部12设有外螺纹且与第二端口延伸部的内螺纹螺接固定。第二端口延伸部的锁紧接头可以很好的实现内管5的密封，在离心或静置时，不会漏液。
所述外管4的顶端设有第一端口10，所述第一端口10上可拆卸连接有封帽3。所述封帽3配合第一端口10可实现将整个双层注射器装置密封的效果，形成独特的封闭式离心装置。
所述第一端口10设有向外凸起的第一端口延伸部，第一端口延伸部为中空凸起的锁紧接头且第一端口延伸部内壁设有内螺纹，所述封帽3内部设有外螺纹且与第一端口延伸部的内螺纹螺接固定。第一端口延伸部的锁紧接头可以很好的实现外管4的密封，在离心或静置时，不会漏液。
优选地，所述第一端口延伸部和第二端口延伸部的锁紧接头均为内部圆锥接头，外套具有螺纹的锁紧接头。
优选地，所述第二端口延伸部为注射针针孔座。第二端口延伸部的注射针针孔座可以和外部注射器活塞机构连接部12配合锁紧，外部注射器推杆6也可以和顶部具有配套针管连接部的注射器任意互联，实现纯化的颗粒脂肪的转移和应用。
本申请的一种用于颗粒脂肪纯化的双层注射器装置的使用过程为：
在使用双层注射器装置进行工作时，先握住外部注射器2的外管4，拉动外部注射器推杆6和外部注射器活塞8抽取脂肪组织，脂肪组织通过第一端口10进入外管4的腔体内，用封帽3密封第一端口10，将整个装置进行离心或静置，脂肪组织充分分层后拉动内部注射器芯杆7和内部注射器活塞9，此时，内部注射器2的内管5内形成另一个放置腔体，通过外部注射器活塞机构连接部12将分层后的上层物质吸取到内管5中，此时外部注射器1的外管4中剩下纯化后的颗粒脂肪和肿胀液等物质，然后将内管5的第二端口13与外部注射器活塞机构连接部12分离，实现将内部注射器2与外部注射器1分离，用顶部具有配套针管连接部的注射器和外部注射器活塞机构连接部12连接，抽取纯化后的颗粒脂肪，进行纯化的颗粒脂肪的转移和应用。
前述对本申请的具体示例性实施方案的描述是为了说明和例证的目的。这些描述并非想将本申请限定为所公开的精确形式，并且很显然，根据上述教导，可以进行很多改变和变化。对示例性实施例进行选择和描述的目的在于解释本申请的特定原理及其实际应用，从而使得本领域的技术人员能够实现并利用本申请的各种不同的示例性实施方案以及各种不同的选择和改变。针对上述示例性实施方案所做的任何简单修改、等同变化与修饰，都应落入本申请的保护范围。
工业实用性
本申请涉及一种用于颗粒脂肪纯化的双层注射器装置，外部注射器包括外管和设置在外管内的外部注射器推杆和外部注射器活塞，内部注射器包括设置在外部注射器推杆内的内管。本申请解决了现有的纯化方式操作繁琐和容易受到污染的问题，从而影响纯化后的颗粒脂肪使用后安全性的技术问题。

Claims (10)

  1. 一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，包括外部注射器(1)和内部注射器(2)，所述外部注射器(1)包括外管(4)和设置在外管(4)内的外部注射器推杆(6)和外部注射器活塞(8)，所述外部注射器推杆(6)为中空结构，所述外部注射器活塞(8)设置在外部注射器推杆(6)的顶端，所述外部注射器活塞(8)的外周面与外管(4)的内壁抵接，所述外部注射器推杆(6)和外部注射器活塞(8)上分别设有开口端；
    所述内部注射器(2)包括设置在外部注射器推杆(6)内的内管(5)，所述内管(5)的顶端设有第二端口(13)，所述第二端口(13)与外部注射器推杆(6)的开口端可拆卸连接。
  2. 根据权利要求1所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述内部注射器(2)还包括设置在内管(5)内的内部注射器芯杆(7)和内部注射器活塞(9)，所述内部注射器活塞(9)设置在内部注射器芯杆(7)的顶端，所述内部注射器活塞(9)的外周面与内管(5)的内壁抵接。
  3. 根据权利要求2所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述外部注射器推杆(6)的开口端设有向内延伸的外部注射器活塞机构连接部(12)，所述第二端口(13)与外部注射器活塞机构连接部(12)可拆卸连接。
  4. 根据权利要求3所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述外管(4)的顶端设有第一端口(10)，所述第一端口(10)上可拆卸连接有封帽(3)。
  5. 根据权利要求4所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述第二端口(13)设有向外凸起的第二端口延伸部，所述第二端口延伸部为中空凸起的锁紧接头且第二端口延伸部内壁设有内螺纹，所述外部注射器活塞机构连接部(12)设有外螺纹且与第二端口延伸部的内螺纹螺接固定。
  6. 根据权利要求5所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述第一端口(10)设有向外凸起的第一端口延伸部，第一端口延伸部为中空凸起的锁紧接头且第一端口延伸部内壁设有内螺纹，所述封帽(3)内部设有外螺纹且与第一端口延伸部的内螺纹螺接固定。
  7. 根据权利要求2所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述内部注射器芯杆(7)的尾端设有内部注射器芯杆握持部(11)，所述内部注射器芯杆握持部(11)为圆柱形结构。
  8. 根据权利要求2所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述外部注射器活塞(8)和内部注射器活塞(9)为橡胶活塞。
  9. 根据权利要求6所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述第一端口延伸部和第二端口延伸部的锁紧接头均为内部圆锥接头，外套具有螺纹的锁紧接头。
  10. 根据权利要求9所述的一种用于颗粒脂肪纯化的双层注射器装置，其特征在于，所述第二端口延伸部为注射针针孔座。
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