WO2023204395A1 - Procédé de fourniture de guide de traitement personnalisé à l'aide de données de diagnostic de lymphœdème, programme d'ordinateur et système - Google Patents
Procédé de fourniture de guide de traitement personnalisé à l'aide de données de diagnostic de lymphœdème, programme d'ordinateur et système Download PDFInfo
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Definitions
- the present invention relates to a method, computer program, and system for providing a customized treatment guide using lymphedema diagnosis data. More specifically, a customized treatment that can apply pressure according to the lymphatic type of the subject's lymphedema using near-infrared images and visible light images. This relates to a method, computer program, and system for providing a customized treatment guide using lymphedema diagnosis data that provides guidance.
- the lymphatic system consists of lymph vessels that carry lymph fluid along with a number of tissues and organs containing lymphoid tissue, a specialized form of reticular connective tissue containing large numbers of lymphocytes.
- the thymic component of various lymphoid organs is composed of epithelial reticular tissue
- the stroma and outer structure of lymphoid tissue are generally composed of a complex network of reticular fibers (desmoplastic cells) and reticular cells (anchoring macrophages). It moves interstitial fluid from the interstitium of tissues between tissues and blood vessels and plays important functions in maintaining homeostasis, metabolism, and immune function.
- lymphatic vessels are known to play an important role in the pathophysiological mechanisms of malignant tumors, lymphedema, and inflammatory diseases.
- Lymphatic vessels are similar in structure to blood vessels, but have thin walls and are joined to large lymph vessels (lymphatic vessels) with many plates and contain lymph capillaries that contain lymph nodes at various locations throughout the body. The areas with the highest concentration of lymph nodes are found in the face and neck, armpits, chest cavity, intestines and groin, and elbows and knees. In general, superficial lymphatic vessels of the epidermis extend along veins, while deep lymphatic vessels extend along arteries. Lymphatic vessels supply lymph throughout the body and return proteins to the cardiovascular system when they leak from the capillaries. Additionally, lymphatic vessels transport fat from the stomach into the blood. In cancer patients, lymphatic tissue has the function of monitoring and defending against foreign cells, bacteria, and cancer cells.
- lymphocytes release substances that directly or indirectly destroy these invaders.
- Other lymphocytes differentiate into plasma cells that secrete antibodies against foreign substances to help remove them.
- Lymph nodes act as filters for foreign substances carried by lymph by their reticular fibrous tissue.
- macrophages destroy foreign substances through phagocytosis.
- lymph nodes produce lymphocytes, some of which are transported in the lymph to other parts of the body as part of the immune defense system.
- the spleen, thymus, and tonsils are lymphoid organs that produce B-cells, T-cells, and lymphocytes, along with antibodies, respectively, to complete the immune defense line of the lymphatic system.
- lymphatic vessels which play a role in draining tissue fluid from the interstitium of tissues, play an important role in immunological defense mechanisms, and the pathophysiological mechanisms of malignant tumors, lymphedema, and inflammatory diseases are known to play an important role in disorders of lymphatic vessel production.
- lymphedema is a condition in which lymphatic fluid is stored under the skin due to lymphatic vessel blockage and abnormal protein accumulation occurs due to damage or blockage of lymphatic vessels. It is a degenerative product of apoptosis. This is the result of obstruction of lymphatic drainage from the lymphoid tissue area.
- lymphatic vessels Infiltration of this obstructive tissue by macrophages leads to the elimination of lymphatic flow through proteolysis of the obstruction protein over a considerable period of time. In this way, when lymphatic vessels malfunction, problems arise in the movement of extracellular fluid and macromolecular substances, which ultimately leads to tissue edema, immune dysfunction, and fibrosis of interstitial tissue. Lymphedema occurs due to hereditary or secondary causes, and lymphedema caused by secondary causes often occurs after treatment of malignant tumors, including surgery and radiation therapy. Acquired edema is reported to occur in more than 45% of patients with breast cancer, the most common cancer in women, and in more than 10% of all cancer patients.
- Related Document 1 Korean Patent Registration No. 10-2134973
- Related Document 2 Korean Patent Publication No. 10-2017-0140791
- a composition for treating, preventing or improving edema and provides a pharmaceutical composition containing an extract or fractionated extract of Butea monosperma as an active ingredient. You can.
- the physical method cannot be a fundamental and efficient treatment method because it intermittently provides massage to the edematous area, and the pharmaceutical method is more objective and quantifiable in that it is administered to the subject through the doctor's subjective confirmation rather than quantified numbers.
- the pharmaceutical method is more objective and quantifiable in that it is administered to the subject through the doctor's subjective confirmation rather than quantified numbers.
- the present inventors need to develop a method to quantitatively and visually identify lymphatic diseases such as lymphedema and provide customized treatment guides.
- the present invention is intended to solve the above problems, and the subject can constantly relieve lymphedema by wearing customized compression garments manufactured in the final development diagram, and is optimized for the lymphatic type of the subject's lymphedema to provide relief effect.
- a customized treatment guide using lymphedema diagnosis data that generates a customized compression garment development diagram for the subject using near-infrared images of ICG injected into the subject's body and visible light images of the subject's body appearance.
- the purpose is to obtain methods, computer programs, and systems.
- the purpose of the present invention is to allow the subject to additionally perform lymphatic edema massage, etc. on the relevant area on his or her own, and to enable medical staff such as physical therapists and doctors to follow up on the subject's lymphedema and confirm the prognosis by referring to it during physical therapy and edema diagnosis. It provides a method, computer program, and system for providing a customized treatment guide using lymphedema diagnosis data that creates a final development diagram of customized compression garments with lymphatic morphology that can quantitatively and visually identify the shape, size, and location of lymphedema. .
- the method of providing a customized treatment guide using lymphedema diagnostic data of the present invention includes a near-infrared image of ICG (Indocyanine green) injected into the subject's body by at least one processor.
- An image acquisition step in which a visible light image of the subject's body appearance is obtained;
- a lymph shape derivation step of deriving a lymph shape including a lymphatic body and a lymph pattern in the subject's body from the near-infrared image by the at least one processor;
- a circumference information measurement step in which the visible light image is converted into a three-dimensional image by the at least one processor, and circumferential information is measured for each section in which the subject's body appearance is divided along the vertical or horizontal axis from the three-dimensional image;
- a raw development drawing step of generating a raw development drawing of the customized compression garment based on the circumference information by the at least one processor;
- a developed view matching step of matching the limp shape to the original developed view by the at least one processor; and a
- the computer program for providing a customized treatment guide using lymphedema diagnosis data of the present invention is stored in a computer-readable recording medium to execute the method for providing a customized treatment guide using lymphedema diagnosis data.
- the system for providing a customized treatment guide using lymphedema diagnostic data of the present invention photographs ICG (Indocyanine green) injected into the subject's body through a near-infrared camera and uses a visible light camera.
- a photographing device that photographs the external appearance of the subject's body; and at least one processor that obtains a near-infrared image and a visible light image from the imaging device and then provides a customized treatment guide suitable for the location and size of the subject's edema.
- the at least one processor acquires a near-infrared image of ICG (Indocyanine green) injected into the subject's body and a visible light image of the subject's body appearance, and obtains a near-infrared image of the subject's body from the near-infrared image.
- ICG Indocyanine green
- Deriving a lymphatic form including lymphatic bodies and lymphatic patterns, converting the visible light image into a three-dimensional image, and measuring circumference information for each section dividing the subject's body appearance along the vertical or horizontal axis from the three-dimensional image, Generating a raw development diagram of the customized compression garment based on the circumference information, matching the lymph shape to the original development drawing, modifying the raw development drawing with the lymph shape matched according to a preset value, and generating a final development drawing. It is characterized by
- the subject's customized compression clothing development diagram is created using the near-infrared image of the ICG injected into the subject's body and the visible light image of the subject's body appearance, so that the subject produces the final development diagram.
- Lymphedema can be alleviated on a regular basis by wearing customized compression clothing, and the relief effect can be improved because compression can be optimized for the lymphatic type of the subject's lymphedema.
- the subject can quantitatively and visually identify the shape, size, and location of his or her lymphedema and can additionally perform lymphatic edema massage, etc., on the relevant area.
- medical staff such as physical therapists and doctors can refer to it during physical therapy and edema diagnosis, and it has a significant effect in tracking the subject's lymphedema and confirming the prognosis.
- Figure 1 is a flowchart of a method for providing a customized treatment guide using lymphedema diagnosis data of the present invention.
- Figure 2 is a diagram showing the geometric relationship on two image planes from the epipolar geometry technique.
- Figure 3 is a diagram showing deriving the size of a lymphatic body through a distance sensor according to an embodiment of the present invention.
- Figure 4 is a diagram showing a visible light image (a), a three-dimensional image (b), and a raw development diagram (c) according to an embodiment of the present invention.
- Figure 5 is a diagram showing a modified development view (a) without the lymph shape displayed and a modified development view (b) with the lymph shape displayed according to an embodiment of the present invention.
- Figure 1 is a flowchart of a method for providing a customized treatment guide using lymphedema diagnosis data of the present invention.
- Figure 2 is a diagram showing the geometric relationship on two image planes from the epipolar geometry technique.
- Figure 3 is a diagram showing deriving the size of a lymphatic body through the distance sensor 111 according to an embodiment of the present invention.
- Figure 4 is a diagram showing a visible light image (a), a three-dimensional image (b), and a raw development diagram (c) according to an embodiment of the present invention.
- Figure 5 is a diagram showing a modified development view (a) without the lymph shape displayed and a modified development view (b) with the lymph shape displayed according to an embodiment of the present invention.
- the system for providing a customized treatment guide using lymphedema diagnostic data of the present invention includes an image acquisition step (S100), a lymphatic shape derivation step (S200), a circumferential information measurement step (S300), and a raw development map generation step (S400). ), a development plan matching step (S500), and a final development plan generation step (S600).
- the image acquisition step (S100) includes a near-infrared image in which ICG (Indocyanine green) injected into the subject's body is captured by at least one processor 200 and the subject's body appearance is captured in the image acquisition step (S100). Visible light images are acquired.
- ICG Indocyanine green
- the term “subject” used in the present invention generally refers to a person receiving a test, and the subject to which the present invention is applied is a person who is suspected or diagnosed with lymphedema and wants to manufacture customized compression clothing suitable for the affected area. It means people.
- ICG used in the present invention is a dark green fluorescent dye (reagent) that binds to albumin, a water-soluble protein.
- the ICG can be injected at a concentration of 0.02 to 0.05 nM.
- the near-infrared image is obtained by radiating near-infrared rays to the body of the subject injected with the ICG, and at this time, the infrared rays that are reflected and emitted in response to the ICG are captured through the near-infrared camera 110 in the imaging device 100. It is an image that has been created.
- the visible light image is an RGB-based image in which the appearance of the ICG-injected area in the subject's body is captured through the visible light camera 120 in the imaging device 100.
- the near-infrared image and the visible light image can be simultaneously captured by the photographing device 100 and acquired through the at least one processor 200.
- a lymph shape including the lymphatic body and lymph pattern in the subject's body is derived from the near-infrared image by the at least one processor 200.
- the lymphatic body refers to a swollen part of the subject's body where waste has accumulated in any lymphatic area and cannot be communicated.
- the lymphatic pattern refers to a shape in which lymphatic bodies captured from the near-infrared image are repeatedly visible.
- the lymph shape derivation step (S200) may use an epipolar geometry technique.
- the conjugate geometry (Epipolar geometry) technique shows that if there are two different planes 'A' and 'B', points P located on the line segment OP of the 'A' plane can be represented as P' points on the 'B' plane. there is.
- point O on the ‘A’ plane, point O on the ‘B’ plane, and point P located on the line segment OP each form a triangle. This means that if the geometric relationship on the two image planes is given and the matching pair P, P’ on the two image planes is given, the three-dimensional spatial coordinates can be determined from these.
- the limp shape derivation step (S200) uses the RANSAC (RANdom Sample Consensus) algorithm to derive spatial coordinates from a plurality of 2D images. By rearranging them, spatial coordinates with improved reliability and accuracy can be obtained.
- RANSAC Random Sample Consensus
- the size of the lymphatic body in the subject's body can be derived using the conjugate geometry technique and the RANSAC algorithm.
- the image acquisition step (S100) is performed by obtaining ICG fluorescence information detected from the distance sensor 111 in the near-infrared camera 110. It can be.
- the imaging device 100 may most preferably be of a shape that can rotate 360 degrees around a part of the subject's body to capture images, and the near-infrared camera 110 and the distance sensor 111 may be rotated.
- the ICG fluorescence expression information refers to the fluorescence intensity of the ICG injected into the subject's body reflected by the lymphatic body and returned to the distance sensor 111. As the distance between the distance sensor 111 and the lymphatic body increases, the ICG fluorescence expression information decreases.
- the surface distance (P n -A), which is the distance between the distance sensor 111 and the outline of the lymphatic body, can be derived as a part of the subject's body rotates as the center from the distance sensor 111. And the surface distance can be used to calculate the internal distance (A'), which is the distance between the center and the outline of the lymphatic body. As the distance sensor 111 rotates, numerous internal distances (A') are calculated, and the size of the lymphatic body can be derived using this.
- the lymph shape derivation step (S200) is a curved surface mechanism that can calculate at least one of the intensity, radiation plus, and incident angle of the light reflected from the curved surface of a part of the subject's body and incident again on the distance sensor 111. It is characterized by reflection.
- the lymphatic pattern can be derived by classifying the pattern of the lymphatic body using a template matching technique.
- the template matching technique is a technique that moves up, down, left, and right on the near-infrared image to find an area similar to a previously stored patch image.
- a plurality of the patch images may be pre-stored in the at least one processor 200 depending on the level of ICG fluorescence.
- the near-infrared image is divided into an XY coordinate system, so the degree to which the patch image is separated from the reference point can be expressed as an
- the lymph shape derivation step (S200) is obtained from a color temperature display step (S210) in which the lymphatic body is displayed in different colors according to the lymph pattern, and the near-infrared image displayed with the color temperature and the image acquisition step (S100). It may include an image matching step (S220) in which one visible light image is matched.
- the color temperature previously stored for each lymphatic pattern may be displayed absolutely, or the color temperature may be displayed relatively according to the degree of ICG fluorescence expression between the lymphatic patterns derived from the near-infrared image. For example, the lymphatic pattern with low ICG fluorescence due to a significant lymphatic volume may be displayed in red, the lymphatic pattern with the next lowest ICG fluorescence may be displayed in yellow, and the lymphatic pattern with the next lowest ICG fluorescence may be displayed in blue.
- the image matching step (S220) can be performed through matching between coordinates using an XY coordinate system. Therefore, through the color temperature display step (S210) and the image matching step (S220) of the present invention, the location of the lymphedema and the most severe part on the subject's body appearance can be visually confirmed, and the There is a significant effect of being reflected in the original development view in the development view matching step (S500) and the final development view generation step (S600) to create a final development view of customized compression clothing to accurately compress the subject's lymphedema area.
- the visible light image is converted into a 3D image by the at least one processor 200, and the subject's body appearance is divided into a vertical or horizontal axis from the 3D image.
- Circumferential information for each section is measured.
- the circumference information may include the circumference length of the body exterior, two-dimensional coordinates, and three-dimensional coordinates.
- Figure 4(a) is a visible light image of the subject's body appearance.
- the imaging device 100 may most preferably be of a shape that can rotate 360 degrees around a part of the subject's body to capture images. Therefore, multiple visible light images taken at different angles can be combined and converted into the three-dimensional image as shown in (b) of FIG. 4.
- the subject's body appearance in the 3D image can be divided along the longitudinal axis and a plurality of sections can be created.
- the standard for selecting the vertical or horizontal axis is the direction of pressure that should be applied to the subject's body.
- the circumference information measurement step (S300) is used to create a more elaborate development diagram because the body does not form a specific shape such as a cylinder or cone, but an irregular shape, and the pressure value to be applied to each section may be different. am.
- the original development plan of the customized compression garment is generated by the at least one processor 200 based on the circumference information.
- the original development diagram can be created in two dimensions as shown in (c) of FIG. 4 solely based on the perimeter information for each section.
- the limp shape is matched to the original developed view by the at least one processor 200.
- the raw developed view may be matched while the visible light image is matched to the near-infrared image whose color temperature is displayed from the image matching step (S220). Therefore, the lymphatic shape can be identified on the primitive development diagram or the modified primitive development diagram.
- the near-infrared camera 110 and the visible light camera 120 are calibrated before the near-infrared image and the visible light image are captured, so that the zero point can be adjusted.
- the primitive development diagram can be XY-coordinated because it is generated by the circumferential information
- the lymph shape can also be XY-coordinated because it is derived from the near-infrared image captured in two dimensions from various directions. Therefore, most preferably, the developed view matching step (S500) can be matched based on the XY coordinates of the original developed view and the lymphatic shape.
- the original development drawing in which the limp shape is matched according to a preset value is modified by the at least one processor 200 and a final development drawing is generated.
- the final development diagram generation step (S600) reflects the preset target pressure value for each section and the lymphatic shape is matched. It may include a target pressure value reflection step (S610) in which the original development diagram is modified.
- the preset target input value for each section may be different depending on the lymph shape derived from the lymph shape derivation step (S200) and the body part of the examinee. For example, looking at (a) to (b) of Figure 5, the subject's body parts are the part of the calf below the knee, the knee, and part of the thigh above the knee, and the part with the color temperature displayed in red according to the lymphatic pattern is above the knee. If it is the thigh area, a previously stored correlation between pressure and circumference information can be used to create a modified development diagram with part of the original development diagram cut off so that the section corresponding to the region can be pressurized to a preset target pressure value.
- the modified development diagram may or may not display the lymphatic form.
- the final development diagram creation step (S600) reflects material information including the elongation rate and pattern reduction rate of the customized compression garment. It may include a material information reflection step (S620) in which the original development diagram to which the lymphatic shape is matched is modified.
- the elongation rate of the material is a numerical expression of the degree to which the material is stretched as a percentage of the ratio between the initial length and the length at breakage.
- the pattern reduction rate is the ratio of manufacturing clothes by shrinking them in consideration of the elongation rate, and is a variable dependent on the elongation rate of the material.
- the preset target pressure value may not be applied to the area to be pressed.
- the area to be pressed may be pressed beyond the preset target pressure value, and the subject may feel considerable discomfort while wearing the customized compression clothing.
- materials with a high elongation rate must increase the pattern reduction rate to increase the pressure on the subject's body when worn.
- the pattern reduction rate must be lowered to reduce the pressure applied to the subject's body when worn.
- material information reflection step (S620) material information including the elongation rate and pattern reduction rate of the material of the customized compression clothing is reflected in order to pressurize according to the target pressure value for each section, thereby reflecting the original development or the target pressure value.
- the revised development drawing can be additionally cut or the already cut portion can be filled.
- the revised and final developed views may or may not display the lymphatic form.
- the limp form to be pressed can be simulated with a modified development drawing modified one or more times according to a preset value.
- the limp shape may be modified through at least one of the length of each section reduced from the target pressure value reflection step (S610) and the length of each section corrected from the material information reflection step (S620).
- the modified limp shape may be simulated and displayed on at least one of the revised development drawing and the final development drawing.
- An output step (S700) may be further included.
- the computer program for providing a customized treatment guide using lymphedema diagnosis data of the present invention is stored in a computer-readable recording medium to execute the method for providing a customized treatment guide using lymphedema diagnosis data described above.
- the system for providing a customized treatment guide using lymphedema diagnosis data of the present invention includes an imaging device 100 and at least one processor 200.
- the imaging device 100 photographs ICG (Indocyanine green) injected into the subject's body through a near-infrared camera 110 and photographs the external appearance of the subject's body through a visible light camera 120.
- the at least one processor 200 acquires a near-infrared image and a visible light image from the imaging device 100 and then provides a customized treatment guide suitable for the location and size of the subject's edema.
- subject used in the present invention generally refers to a person receiving a test, and the subject to which the present invention is applied is a person who is suspected or diagnosed with lymphedema and wants to manufacture customized compression garments suitable for the affected area. it means.
- ICG used in the present invention is a dark green fluorescent dye (reagent) that binds to albumin, a water-soluble protein.
- the ICG can be injected at a concentration of 0.02 to 0.05 nM.
- the near-infrared image is an image in which near-infrared rays are irradiated to the body of a subject injected with the ICG, and the infrared rays reflected and emitted in response to the ICG are captured through the near-infrared camera 110.
- the visible light image is an RGB-based image in which the appearance of the ICG-injected area in the subject's body is captured through the visible light camera 120.
- the near-infrared image and the visible light image may be simultaneously captured by the photographing device 100, and the at least one processor 200 may capture the near-infrared image and the visible light through a wired or wireless communication method with the photographing device 100. Images can be obtained.
- the imaging device 100 may most preferably be in a shape of a shape that can rotate 360 degrees around a part of the subject's body to capture images, and the near-infrared camera 110 and the near-infrared camera 110 are provided on one side.
- the distance sensor 111 and the visible light camera 120 may rotate simultaneously.
- the at least one processor 200 may acquire a near-infrared image of ICG (Indocyanine green) injected into the subject's body and a visible light image of the external appearance of the subject's body.
- ICG Indocyanine green
- the at least one processor 200 may derive a lymphatic shape including the lymphatic body and movement pattern in the subject's body from the near-infrared image.
- the lymphatic body refers to a swollen part of the subject's body where waste has accumulated in any lymphatic area and cannot be communicated.
- the lymphatic pattern refers to a shape in which lymphatic bodies captured from the near-infrared image are repeatedly visible.
- the at least one processor 200 may acquire a plurality of two-dimensional near-infrared images from the near-infrared camera 110.
- the at least one processor 200 may use an epipolar geometry technique. Referring to Figure 2, the conjugate geometry (Epipolar geometry) technique shows that if there are two different planes 'A' and 'B', points P located on the line segment OP of the 'A' plane can be represented as P' points on the 'B' plane. there is.
- point O on the ‘A’ plane, point O on the ‘B’ plane, and point P located on the line segment OP each form a triangle. This means that if the geometric relationship on the two image planes is given and the matching pair P, P’ on the two image planes is given, the three-dimensional spatial coordinates can be determined from these.
- the at least one processor 200 uses the RANSAC (RANdom Sample Consensus) algorithm to calculate spatial coordinates derived from a plurality of two-dimensional images. By rearranging them, spatial coordinates with improved reliability and accuracy can be obtained.
- the at least one processor 200 may derive the size of the lymphatic body in the subject's body using the conjugate geometry technique and the RANSAC algorithm.
- the distance sensor 111 in the near-infrared camera 110 can detect and then obtain ICG fluorescence information.
- the imaging device 100 may most preferably be of a shape that can rotate 360 degrees around a part of the subject's body to capture images, and the near-infrared camera 110 and the distance sensor 111 may be rotated.
- the ICG fluorescence expression information refers to the fluorescence intensity of the ICG injected into the subject's body reflected by the lymphatic body and returned to the distance sensor 111. As the distance between the distance sensor 111 and the lymphatic body increases, the ICG fluorescence expression information decreases.
- the distance sensor 111 can detect the surface distance (P n -A), which is the distance between the distance sensor 111 and the outline of the lymphatic body, while rotating around a part of the subject's body. And the at least one processor 200 can use the surface distance to calculate an internal distance (A'), which is the distance between the center and the outline of the lymphatic body.
- the distance sensor 111 detects the surface distance (P n -A) at different angles as it rotates, and the at least one processor 200 uses this to calculate countless internal distances (A'). Then, using this, the size of the lymphatic body can be derived.
- the at least one processor 200 includes a curved surface mechanism capable of calculating at least one of the intensity, radiation plus, and incident angle of light reflected from the curved surface of a part of the subject's body and incident again on the distance sensor 111. It is characterized by reflection.
- the at least one processor 200 may derive the lymphatic pattern by classifying the pattern of the lymphatic body using a template matching technique.
- the template matching technique is a technique that moves up, down, left, and right on the near-infrared image to find an area similar to a previously stored patch image.
- the at least one processor 200 may store a plurality of the patch images according to the level of ICG fluorescence expression. At this time, the near-infrared image is divided into an XY coordinate system, so the degree to which the patch image is separated from the reference point can be expressed as an
- the at least one processor 200 displays the lymphatic body in different colors according to the lymphatic pattern, and displays the near-infrared image with the color temperature and the visible light image captured by the visible light camera 120. It is characterized by matching.
- the at least one processor 200 may absolutely display the pre-stored color temperature for each lymphatic pattern, or may relatively display the color temperature according to the degree of ICG fluorescence expression between the lymphatic patterns derived from the near-infrared image. For example, the lymphatic pattern with low ICG fluorescence due to a significant lymphatic volume may be displayed in red, the lymphatic pattern with the next lowest ICG fluorescence may be displayed in yellow, and the lymphatic pattern with the next lowest ICG fluorescence may be displayed in blue.
- the at least one processor 200 may perform registration through matching between coordinates using the XY coordinate system. Therefore, the present invention can visually confirm the location of the lymphedema and the most severe part of the subject's body appearance, and in the next process, the color temperature is reflected in the hyperopic development diagram to accurately apply pressure to the subject's lymphedema area. It has a remarkable effect in creating the final development of compression garments.
- the at least one processor 200 may convert the visible light image into a 3D image and measure circumferential information for each section by dividing the subject's body appearance along the vertical or horizontal axis from the 3D image.
- the circumference information may include the circumference length of the body exterior, two-dimensional coordinates, and three-dimensional coordinates.
- Figure 4(a) is a visible light image of the subject's body appearance.
- the imaging device 100 may most preferably be of a shape that can rotate 360 degrees around a part of the subject's body to capture images.
- the at least one processor 200 can combine multiple visible light images taken at different angles and convert them into the three-dimensional image as shown in (b) of FIG. 4.
- the at least one processor 200 can segment the subject's body appearance along the longitudinal axis in the 3D image and create a plurality of sections.
- the standard for selecting the vertical or horizontal axis is the direction of pressure that should be applied to the subject's body. This is to create a more elaborate development diagram because the body does not have a specific shape such as a cylinder or cone, but an irregular shape, and the pressure value that must be applied to each section may be different.
- the at least one processor 200 generates a raw development diagram of the customized compression garment based on the circumference information.
- the original development diagram can be created in two dimensions as shown in (c) of FIG. 4 solely based on the perimeter information for each section.
- the at least one processor 200 matches the limp shape to the original development diagram.
- the at least one processor 200 may match the raw development diagram in a state in which the visible light image is matched to the near infrared image in which the color temperature is displayed. Therefore, the lymphatic shape can be identified on the primitive development diagram or the modified primitive development diagram.
- the near-infrared camera 110 and the visible light camera 120 can each be calibrated to adjust their zero points.
- the primitive development diagram can be XY-coordinated because it is generated by the circumferential information
- the lymph shape can also be XY-coordinated because it is derived from the near-infrared image captured in two dimensions from various directions. Therefore, most preferably, the at least one processor 200 can match the original development diagram and the limp form based on the XY coordinates.
- the at least one processor 200 modifies the original development diagram in which the limp shape is matched according to a preset value and generates a final development diagram.
- the at least one processor 200 when modifying the raw development diagram in which the limping shape is matched using a preset value, the at least one processor 200 reflects the preset target pressure value for each section to match the limping shape.
- the original development diagram can be modified.
- the preset target input value for each section may be different depending on the lymph type and body part of the examinee. For example, looking at (a) to (b) of Figure 5, the subject's body parts are the part of the calf below the knee, the knee, and part of the thigh above the knee, and the part with the color temperature displayed in red according to the lymphatic pattern is above the knee. If it is the thigh area, a modified development diagram with part of the original development diagram cut off can be generated using the correlation between the previously stored pressure and circumference information so that the section corresponding to the region can be pressurized to a preset target pressure value.
- the modified development diagram may or may not display the lymphatic form.
- the at least one processor 200 when modifying the primitive development diagram in which the lymph shape is matched using a preset value, the at least one processor 200 reflects material information including an elongation rate and a pattern reduction rate of the customized compression garment.
- the primitive development diagram in which the lymphatic shape is matched can be modified.
- the elongation rate of the material is a numerical expression of the degree to which the material is stretched as a percentage of the ratio between the initial length and the length at breakage.
- the pattern reduction rate is the ratio of manufacturing clothes by shrinking them in consideration of the elongation rate, and is a variable dependent on the elongation rate of the material.
- the preset target pressure value may not be applied to the area to be pressed, and even if the subject wears the customized compression clothing, edema may occur.
- the alleviating effect may be significantly reduced.
- the customized compression clothing is made of a material that does not stretch well, the area to be pressed may be pressed beyond the preset target pressure value, and the subject may feel considerable discomfort while wearing the customized compression clothing. there is.
- materials with a high elongation rate must increase the pattern reduction rate to increase the pressure on the subject's body when worn.
- the pattern reduction rate must be lowered to reduce the pressure applied to the subject's body when worn.
- the at least one processor 200 reflects material information including the elongation rate and pattern reduction rate of the material of the customized compression garment in order to pressurize according to the target pressure value for each section, thereby reflecting the original development or the target pressure value. You can additionally cut the modified development drawing or perform corrections to fill in the parts that have already been cut.
- the revised and final developed views may or may not display the lymphatic form.
- the at least one processor 200 may simulate the limp shape to be pressed with a modified development diagram modified one or more times according to a preset value.
- the limp shape may be modified through at least one of the length of each section reduced by reflecting the target pressure value and the length of each section modified by reflecting the material information.
- the at least one processor 200 may simulate the modified limp shape and display it on at least one of the modified development view and the final development view.
- the system for providing a customized treatment guide using lymphedema diagnosis data of the present invention may further include an output device 300 that outputs the final development of the customized compression garment generated by the at least one processor 200.
- the at least one processor 200 and the output device 300 can transmit and receive the final development diagram through wired or wireless communication methods.
- the subject can constantly relieve lymphedema by wearing customized compression clothing made according to the final development diagram. And since compression can be optimized for the lymphatic type of the subject's lymphedema, the relief effect can be improved.
- the subject can intuitively understand the shape, size, and location of his/her lymphedema and can additionally perform lymphatic edema massage on the relevant area.
- medical staff such as physical therapists and doctors can refer to it during physical therapy and edema diagnosis, and it has a significant effect in tracking the subject's lymphedema and confirming the prognosis.
- Embodiments may be implemented by hardware, software, firmware, middleware, microcode, hardware description language, or any combination thereof.
- program code or code segments that perform necessary tasks may be stored in a computer-readable storage medium and executed by one or more processors.
- aspects of the subject matter described herein may be described in the general context of computer-executable instructions, such as program modules or components that are executed by a computer.
- program modules or components include routines, programs, objects, and data structures that perform specific tasks or implement specific data types.
- aspects of the subject matter described herein may be practiced in distributed computing environments where tasks are performed by remote processing devices that are linked through a communications network.
- program modules may be located in both local and remote computer storage media, including memory storage devices.
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Abstract
La présente invention concerne un procédé permettant de fournir un guide de traitement personnalisé à l'aide de données de diagnostic de lymphœdème, un programme d'ordinateur et un système et, plus particulièrement, un procédé permettant de fournir un guide de traitement personnalisé à l'aide de données de diagnostic de lymphœdème, un programme d'ordinateur et un système, le procédé comprenant : une étape d'acquisition d'image dans laquelle au moins un processeur acquiert une image proche infrarouge dans laquelle le vert d'indocyanine (ICG) injecté dans le corps d'un sujet est capturé et une image de lumière visible dans laquelle l'extérieur du corps du sujet est capturé ; une étape de dérivation de forme lymphatique dans laquelle ledit processeur dérive, à partir de l'image proche infrarouge, une forme lymphatique comprenant une accumulation de lymphe et un motif lymphatique dans le corps du sujet ; une étape de mesure d'informations de circonférence dans laquelle ledit processeur convertit l'image de lumière visible en une image tridimensionnelle et mesure, à partir de l'image tridimensionnelle, des informations de circonférence pour chaque section formée par segmentation de l'extérieur du corps du sujet le long d'un axe longitudinal ou d'un axe transversal ; une étape de génération de vue en plan brute dans laquelle ledit processeur génère une vue en plan brute d'un vêtement de compression personnalisé sur la base des informations de circonférence ; une étape de mise en correspondance de vue en plan dans laquelle ledit processeur fait correspondre la forme lymphatique à la vue en plan brute ; et une étape de génération de vue en plan finale dans laquelle ledit processeur modifie, selon une valeur numérique prédéfinie, la vue en plan brute à laquelle la forme lymphatique correspond et génère une vue en plan finale.
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KR20190139545A (ko) * | 2018-06-08 | 2019-12-18 | 주식회사 포튼가먼트 | 고객의 체형정보를 자동 수집하여 빅데이터를 구축하고 관리, 분류, 활용하는 자동시스템 |
US20200323697A1 (en) * | 2019-04-09 | 2020-10-15 | Trestech Co., Ltd. | Cylindrical bandage |
US20210085529A1 (en) * | 2019-08-31 | 2021-03-25 | Michael J. Weiler | Methods And Systems For Fitting Compression Garments From Digital Imagery |
WO2021099251A1 (fr) * | 2019-11-18 | 2021-05-27 | Thuasne | Vêtement de compression et/ou de contention pour le traitement du lymphoedème |
KR20210109742A (ko) * | 2020-02-28 | 2021-09-07 | (주)에스원바이오 | 림프부종 진단을 위한 씨암형 촬영장치 |
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KR20170140791A (ko) | 2016-06-13 | 2017-12-21 | 성균관대학교산학협력단 | 부종의 치료, 예방 또는 개선용 조성물 |
KR102134973B1 (ko) | 2018-11-13 | 2020-07-16 | 주식회사 바디프랜드 | 부종 상태를 고려하여 림프순환을 돕는 마사지를 제공하는 마사지 장치 및 방법 |
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KR20190139545A (ko) * | 2018-06-08 | 2019-12-18 | 주식회사 포튼가먼트 | 고객의 체형정보를 자동 수집하여 빅데이터를 구축하고 관리, 분류, 활용하는 자동시스템 |
US20200323697A1 (en) * | 2019-04-09 | 2020-10-15 | Trestech Co., Ltd. | Cylindrical bandage |
US20210085529A1 (en) * | 2019-08-31 | 2021-03-25 | Michael J. Weiler | Methods And Systems For Fitting Compression Garments From Digital Imagery |
WO2021099251A1 (fr) * | 2019-11-18 | 2021-05-27 | Thuasne | Vêtement de compression et/ou de contention pour le traitement du lymphoedème |
KR20210109742A (ko) * | 2020-02-28 | 2021-09-07 | (주)에스원바이오 | 림프부종 진단을 위한 씨암형 촬영장치 |
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