WO2023173575A1 - Dispositif d'imagerie de test de charge par résonance magnétique - Google Patents

Dispositif d'imagerie de test de charge par résonance magnétique Download PDF

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Publication number
WO2023173575A1
WO2023173575A1 PCT/CN2022/093547 CN2022093547W WO2023173575A1 WO 2023173575 A1 WO2023173575 A1 WO 2023173575A1 CN 2022093547 W CN2022093547 W CN 2022093547W WO 2023173575 A1 WO2023173575 A1 WO 2023173575A1
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WO
WIPO (PCT)
Prior art keywords
closed box
box
magnetic resonance
lying
top cover
Prior art date
Application number
PCT/CN2022/093547
Other languages
English (en)
Chinese (zh)
Other versions
WO2023173575A9 (fr
Inventor
戴卓智
吴先衡
林黛英
沈君
Original Assignee
戴卓智
吴先衡
林黛英
沈君
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202210269248.2A external-priority patent/CN114521888A/zh
Priority claimed from CN202220595524.XU external-priority patent/CN217390702U/zh
Application filed by 戴卓智, 吴先衡, 林黛英, 沈君 filed Critical 戴卓智
Publication of WO2023173575A1 publication Critical patent/WO2023173575A1/fr
Publication of WO2023173575A9 publication Critical patent/WO2023173575A9/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging

Definitions

  • the present invention relates to auxiliary equipment for medical diagnosis, in particular to a device for magnetic resonance stress experimental imaging.
  • Magnetic resonance imaging plays an important role in cardiac examination for medical diagnosis and can effectively evaluate the structure and function of cardiac soft tissue.
  • cardiac examination for subjects with coronary artery disease, due to the body's compensatory effect, it is difficult to accurately assess the condition at rest. Therefore, in clinical practice, it is often necessary to increase cardiac oxygen consumption through stress experiments to achieve a loading state, to diagnose early coronary artery disease, or to monitor and evaluate confirmed patients.
  • An improved exercise method is a multifunctional load experimental exercise device and system for magnetic resonance imaging disclosed in Chinese Invention Patent Application No. 201810012520.2, and its application. It is to set a horizontal foot exercise device on the lying table of the magnetic resonance imaging equipment. , using reciprocating foot movement, the exercise load during magnetic resonance scanning can be achieved.
  • the disadvantage of this device is that the movement is local movement and requires effective cooperation from the subject.
  • Drug method that is, injecting vasodilator drugs to increase the heart load.
  • Commonly used drugs include dipyridamole, adenosine, regadenosine, and dobutamine.
  • the stress induced by drugs and the cardiac load under physiological conditions.
  • the controllability is poor, and some subjects are at risk of adverse drug reactions.
  • the purpose of the present invention is to provide a new device for magnetic resonance stress experimental imaging that can overcome the defects of the existing technology.
  • a device for magnetic resonance stress experiment imaging which is characterized by: including a closed box for the subject to lie inside and a heater for generating hot air.
  • the closed box is provided with a box air inlet and a box air outlet.
  • the air outlet of the heater is connected to the box air inlet through a hot air delivery pipe.
  • the front end of the closed box is provided with a box air inlet and a box air outlet.
  • the closed box is composed of a base with a lying cavity and a top cover that can be closed on the opening above the lying cavity of the base. , there is a breathable lying platform in the lying cavity, the top cover is provided with a ventilation hole that can be opened from the inside of the box, and the entire closed box is made of non-metallic materials.
  • the closed box of the above technical solution may be provided with a first hand-held control balloon that controls the heater to stop delivering hot air.
  • the trachea of the first hand-held control balloon passes through the closed box and is connected to the closed box.
  • the pipe opening on the closed box through which the trachea of the first hand-held control balloon passes may be provided with a sealing ring.
  • the closed box of the above technical solution may be provided with an expansion opening for external equipment or its operator to be placed in the closed box.
  • the external equipment or its operator to be placed in the closed box may be a control magnet.
  • the connecting pipeline of the external device or its operator can be connected to the outside of the closed box through the expansion hole.
  • the expansion opening may be equipped with a sealing ring.
  • the ventilation hole on the top cover may be composed of several ventilation holes, and the inside of the top cover is provided with an orifice door that can close or open the ventilation hole.
  • the aperture door in the above technical solution may be slidably fitted on a slide rail on the inner top surface of the top cover, and a handle is provided on the aperture door to control the opening or closing of the aperture door.
  • the neck of the closed box described in the above technical solution can be provided with a sealing ring, and the sealing ring can be made of soft non-metallic material.
  • the sealing ring may be composed of a lower half ring disposed on the base and an upper half ring disposed on the top cover that fit together.
  • the air inlet of the box in the above technical solution can be provided at the foot end of the box, and the air outlet of the box can be provided at the head end of the box.
  • the breathable lying platform in the lying cavity of the above technical solution can be composed of a lying board placed in the lying cavity, or can be composed of a boss formed integrally with the lying cavity, and the ventilation lying platform is distributed on There are breathable grooves to allow hot air to heat the back of the person being tested.
  • the heater described in the above technical solution may be provided with an automatic hot air temperature control regulator.
  • the shapes of the box and the lying cavity in the above technical solution can adopt any applicable shape.
  • the outer portions of the base and the top cover may be provided with corresponding buckles respectively, so that the top cover can be fixed when the top cover is closed on the top side of the base.
  • a sealing gasket may be provided on the snapping edge of the base and the top cover.
  • the hot air in the above technical solution can be dry hot air or moist hot air, and the heater or the closed box can be provided with a hot air conveying fan.
  • the beneficial effects of the present invention are: because the present invention allows the subject to lie in a closed box made of non-metallic material, and the subject's head is exposed outside the closed box, the hot air is transported into the closed box through the heater. In the closed box, the temperature inside the box where the subject is located is controlled and appropriately increased, thereby increasing the heart rate of the subject, increasing myocardial oxygen consumption, and reaching a stress test state. At the same time, a magnetic resonance imaging scanner is used The subject in this load test state is detected and imaged. Therefore, the "heat load method" of the present invention has low cost to obtain the load test state, has no drug side effects on the human body, has good controllability, and can perform real-time dynamic monitoring.
  • the stress test state is relatively stable and ideal, which effectively improves the effect of magnetic resonance stress imaging. Since the structure of the invention is perfect and simple, the temperature inside the closed box rises evenly, the testee has good effect in obtaining the load test state, and the use is safe and reliable, the purpose of the invention can be ideally realized.
  • Figure 1 is a schematic diagram of an embodiment of the present invention.
  • Figure 2 is a schematic top view of the base of the closed box of Figure 1 with the top cover removed.
  • Figure 3 is a schematic top view of the top cover of the closed box in Figure 1 .
  • Figure 4 is a schematic diagram of the top cover of Figure 3 turned over.
  • this device for magnetic resonance stress experimental imaging is characterized by: including a closed box 1 for the subject to lie inside and a heater 2 that generates hot air.
  • the box 1 is provided with a box air inlet 3 and a box air outlet 4.
  • the air outlet 5 of the heater 2 is connected to the box air inlet 3 through a hot air delivery pipe 6.
  • the closed box 1 The front end is provided with a neck opening 7 for the subject's head to extend out of the closed box 1.
  • the closed box 1 consists of a base 9 with a lying cavity 8 and a cover that can be covered in the base 9. It consists of a top cover 10 with an opening above the lying chamber 8.
  • a breathable lying platform 11 is provided in the lying chamber 8.
  • the top cover 10 is provided with a ventilation hole 12 that can be opened from inside the box.
  • the entire The closed box 1 is made of non-metallic materials.
  • the closed box 1 is provided with a first hand-held control balloon 13 for controlling the heater to stop delivering hot air.
  • the air tube 14 of the first hand-held control balloon 13 passes through the closed box.
  • the body 1 is connected to the pneumatic switch of the heater 2.
  • the pipe opening 15 of the closed box 1 for the trachea 14 of the first hand-held control balloon 13 to pass through is provided with a sealing ring.
  • the closed box 1 is provided with an expansion opening 16 for external equipment or its operator to be put into the closed box 1.
  • the external equipment or its operator placed into the closed box 1 is a control unit.
  • the magnetic resonance scan pauses the second hand-held control balloon 17 for scanning.
  • the connecting pipeline 18 of the second hand-held control balloon 17 is connected to the docking device outside the closed box 1 through the expansion hole 16, so
  • the expansion opening 16 is provided with a sealing ring.
  • the ventilation hole 12 on the top cover 10 is composed of several ventilation holes.
  • the inside of the top cover 10 is provided with orifice doors 19 and 20 that can close or open the ventilation hole 12 .
  • the orifice doors 19 and 20 are slidably fitted on the slide rails 21 and 22 on the inner top surface of the top cover 10.
  • the orifice doors 19 and 20 are respectively provided with handles 23 and 24 for controlling the Closing or opening of orifice doors 19, 20.
  • the neck opening 7 of the closed box 1 is provided with a sealing ring, and the sealing ring is made of soft non-metallic material.
  • the sealing ring is composed of a lower half ring 25 provided on the base 9 and an upper half ring 26 provided on the top cover 10 that fit together.
  • the box air inlet 3 is located at the foot end of the base 9
  • the box air outlet 4 is located at the head end of the top cover 10 .
  • the breathable lying platform 11 in the lying chamber is composed of a boss formed integrally with the lying chamber 8.
  • the breathable lying platform 11 is distributed with ventilation grooves 27 so that the hot air can heat the body of the person being tested. back.
  • the heater 2 is provided with an automatic hot air temperature control regulator 28 .
  • the outer parts of the base 9 and the top cover 10 are respectively provided with corresponding buckles 29 and the like, so that the top cover 10 can be fixed when the top cover 10 is closed above the opening of the lying cavity 8 of the base 9 .
  • Sealing gaskets may be provided on the fastening edges 30 and 31 of the base 9 and the top cover 10 .
  • the hot air output by the heater 2 can be dry hot air or moist hot air.
  • the heater 2 is provided with a hot air conveying fan 32 .
  • the top cover 10 is opened in the state shown in Figure 1, and the base 9 becomes the state shown in Figure 2, and the subject is allowed to lie on the base 9.
  • the subject's neck is pillowed on the lower half ring 25 of the sealing ring, and the head is exposed outside the neck opening 7 of the closed box 1; then the top cover 10 is closed Seal the lying chamber 8 on the open opening above the lying chamber 8 of the base 9; then start the heater 2 to transport hot air into the closed box 1, and the temperature inside the box gradually increases.
  • the subject's heart rate and myocardial oxygen consumption increase, reaching the stress test state; at this time, the magnetic resonance imaging equipment performs stress experiment imaging detection on the subject in the closed box 1 from outside the closed box 1 ;
  • the first hand-held control balloon 13 can be squeezed to control the heater 2 to stop delivering hot air, and the second hand-held control balloon 13 can be squeezed at the same time.
  • Control the balloon 17 to control the magnetic resonance imaging equipment to pause scanning; then push the handles 23 and 24 to control the opening of the orifice doors 19 and 20 to allow the hot air in the closed box 1 to pass through the ventilation orifice. 12 is discharged to quickly reduce the temperature inside the closed box 1.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

Un dispositif d'imagerie de test de charge par résonance magnétique, résolvant les problèmes selon lesquels, dans un test de charge existant à l'aide d'un "procédé d'exercice", la surveillance ne peut pas être effectuée en temps réel, seul un mouvement local est réfléchi, et une coopération d'exercice efficace d'un sujet de test est requise, ou dans un test de charge existant à l'aide d'un "procédé de médicament", l'état de celui-ci est différent de l'état d'un test de charge dans un état physiologique, la contrôlabilité est médiocre, et des risques de réaction de médicament défavorables existent. Le dispositif comprend un corps de boîte fermé (1) pour un sujet de test destiné à se trouver à l'intérieur et un dispositif de chauffage (2) pour générer de l'air chaud ; une entrée d'air de corps de boîte (3) et une sortie d'air de corps de boîte (4) sont formées sur le corps de boîte fermé (1) ; une sortie d'air de dispositif de chauffage (5) est reliée à l'entrée d'air de corps de boîte (3) au moyen d'un tuyau de transport d'air chaud (6) ; une ouverture de col (7) pour la tête du sujet de test pour s'étendre hors du corps de boîte fermé (1) est formée au niveau d'une partie d'extrémité avant du corps de boîte fermé (1) ; le corps de boîte fermé (1) est constitué d'une base (9) ayant une cavité de couchage (8) et un couvercle supérieur (10) qui peut recouvrir une ouverture au niveau d'une partie supérieure de la cavité de couchage (8) de la base (9) ; une table de couchage perméable à l'air (11) est disposée dans la cavité de couchage (8) ; des trous d'aération (12) qui peuvent être actionnés et ouverts depuis l'intérieur d'une boîte sont formés sur le couvercle supérieur (10) ; le corps de boîte fermé entier (1) est constitué de matériaux non métalliques.
PCT/CN2022/093547 2022-03-18 2022-05-18 Dispositif d'imagerie de test de charge par résonance magnétique WO2023173575A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202210269248.2A CN114521888A (zh) 2022-03-18 2022-03-18 一种用于磁共振负荷实验成像的装置
CN202220595524.XU CN217390702U (zh) 2022-03-18 2022-03-18 一种用于磁共振负荷实验成像的装置
CN202210269248.2 2022-03-18
CN202220595524.X 2022-03-18

Publications (2)

Publication Number Publication Date
WO2023173575A1 true WO2023173575A1 (fr) 2023-09-21
WO2023173575A9 WO2023173575A9 (fr) 2024-03-14

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2071513U (zh) * 1990-07-31 1991-02-20 曲忠军 人体心功能检测负压仓
JPH06217961A (ja) * 1993-01-29 1994-08-09 Toshiba Corp 磁気共鳴診断装置
US6066087A (en) * 1995-07-21 2000-05-23 Tron; Margherita Exercise bed for aesthetic and slimming treatments
CN108042135A (zh) * 2018-01-05 2018-05-18 郜发宝 一种磁共振成像用多功能负荷实验运动装置和系统及其应用
CN108056820A (zh) * 2016-11-09 2018-05-22 韦伯斯特生物官能(以色列)有限公司 用于心脏损伤评估的磁共振成像(mri)温度记录法
CN113520762A (zh) * 2021-04-15 2021-10-22 江苏力磁医疗设备有限公司 一种婴儿转运设备、成像设备及婴儿转移成像系统
CN214965546U (zh) * 2021-04-09 2021-12-03 安徽医科大学第一附属医院 一种医用心脏磁共振检查负压固定检查垫

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2071513U (zh) * 1990-07-31 1991-02-20 曲忠军 人体心功能检测负压仓
JPH06217961A (ja) * 1993-01-29 1994-08-09 Toshiba Corp 磁気共鳴診断装置
US6066087A (en) * 1995-07-21 2000-05-23 Tron; Margherita Exercise bed for aesthetic and slimming treatments
CN108056820A (zh) * 2016-11-09 2018-05-22 韦伯斯特生物官能(以色列)有限公司 用于心脏损伤评估的磁共振成像(mri)温度记录法
CN108042135A (zh) * 2018-01-05 2018-05-18 郜发宝 一种磁共振成像用多功能负荷实验运动装置和系统及其应用
CN214965546U (zh) * 2021-04-09 2021-12-03 安徽医科大学第一附属医院 一种医用心脏磁共振检查负压固定检查垫
CN113520762A (zh) * 2021-04-15 2021-10-22 江苏力磁医疗设备有限公司 一种婴儿转运设备、成像设备及婴儿转移成像系统

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