WO2023173575A1

WO2023173575A1 - Device for magnetic resonance load test imaging

Info

Publication number: WO2023173575A1
Application number: PCT/CN2022/093547
Authority: WO
Inventors: 戴卓智; 吴先衡; 林黛英; 沈君
Original assignee: 戴卓智; 吴先衡; 林黛英; 沈君
Priority date: 2022-03-18
Filing date: 2022-05-18
Publication date: 2023-09-21
Also published as: WO2023173575A9

Abstract

A device for magnetic resonance load test imaging, solving the problems that in an existing load test using an "exercise method", monitoring cannot be performed in real-time, only local movement is reflected, and effective exercise cooperation of a test subject is required, or in an existing load test using a "drug method", the state thereof is different from the state of a load test under a physiological state, controllability is poor, and adverse drug reaction risks exist. The device comprises a closed box body (1) for a test subject to lie inside and a heater (2) for generating hot air; a box body air inlet (3) and a box body air outlet (4) are formed on the closed box body (1); a heater air outlet (5) is connected to the box body air inlet (3) by means of a hot air conveying pipe (6); a neck opening (7) for the head of the test subject to extend out of the closed box body (1) is formed at a front end portion of the closed box body (1); the closed box body (1) consists of a base (9) having a lying cavity (8) and a top cover (10) that can cover an opening at an upper portion of the lying cavity (8) of the base (9); an air-permeable lying table (11) is provided in the lying cavity (8); vent holes (12) that can be operated and opened from the inside of a box are formed on the top cover (10); the entire closed box body (1) is made of non-metallic materials.

Description

A device for magnetic resonance stress experimental imaging

Technical field

The present invention relates to auxiliary equipment for medical diagnosis, in particular to a device for magnetic resonance stress experimental imaging.

Background technique

Magnetic resonance imaging plays an important role in cardiac examination for medical diagnosis and can effectively evaluate the structure and function of cardiac soft tissue. However, for subjects with coronary artery disease, due to the body's compensatory effect, it is difficult to accurately assess the condition at rest. Therefore, in clinical practice, it is often necessary to increase cardiac oxygen consumption through stress experiments to achieve a loading state, to diagnose early coronary artery disease, or to monitor and evaluate confirmed patients.

There are currently two main methods of load testing: 1. "Exercise method", which increases the load on the body through the physical movement of the subject. For example, when walking on a treadmill or riding an exercise bike, perform a magnetic resonance examination after reaching the load requirement. The biggest flaw of this method is that it cannot be monitored in real time. The person being tested is in a state of stopping motion when scanning. An improved exercise method is a multifunctional load experimental exercise device and system for magnetic resonance imaging disclosed in Chinese Invention Patent Application No. 201810012520.2, and its application. It is to set a horizontal foot exercise device on the lying table of the magnetic resonance imaging equipment. , using reciprocating foot movement, the exercise load during magnetic resonance scanning can be achieved. However, the disadvantage of this device is that the movement is local movement and requires effective cooperation from the subject. For subjects with combined movement disorders, Otherwise, it will be difficult to form an effective load. 2. "Drug method", that is, injecting vasodilator drugs to increase the heart load. Commonly used drugs include dipyridamole, adenosine, regadenosine, and dobutamine. However, there is a certain difference between the stress induced by drugs and the cardiac load under physiological conditions. Moreover, once the drug is injected into the human body, the controllability is poor, and some subjects are at risk of adverse drug reactions.

technical problem

In order to overcome the existing "exercise method" load test status that cannot be monitored in real time, only reflects local motion, and requires effective exercise cooperation of the subject, and the "drug method" load test status is different from the physiological state, and can be It has problems such as poor controllability and risk of adverse drug reactions. The purpose of the present invention is to provide a new device for magnetic resonance stress experimental imaging that can overcome the defects of the existing technology.

Technical solutions

The technical solution adopted by the present invention to solve the technical problem is: a device for magnetic resonance stress experiment imaging, which is characterized by: including a closed box for the subject to lie inside and a heater for generating hot air. The closed box is provided with a box air inlet and a box air outlet. The air outlet of the heater is connected to the box air inlet through a hot air delivery pipe. The front end of the closed box is provided with a box air inlet and a box air outlet. A neck opening for the subject's head to extend outside the closed box. The closed box is composed of a base with a lying cavity and a top cover that can be closed on the opening above the lying cavity of the base. , there is a breathable lying platform in the lying cavity, the top cover is provided with a ventilation hole that can be opened from the inside of the box, and the entire closed box is made of non-metallic materials.

The closed box of the above technical solution may be provided with a first hand-held control balloon that controls the heater to stop delivering hot air. The trachea of the first hand-held control balloon passes through the closed box and is connected to the closed box. For the pneumatic switch of the heater, the pipe opening on the closed box through which the trachea of the first hand-held control balloon passes may be provided with a sealing ring.

The closed box of the above technical solution may be provided with an expansion opening for external equipment or its operator to be placed in the closed box. The external equipment or its operator to be placed in the closed box may be a control magnet. A second hand-held control balloon for resonant scanning and pause scanning, an electrocardiographic device with electromagnetic shielding, etc. The connecting pipeline of the external device or its operator can be connected to the outside of the closed box through the expansion hole. For docking equipment, the expansion opening may be equipped with a sealing ring.

In the above technical solution, the ventilation hole on the top cover may be composed of several ventilation holes, and the inside of the top cover is provided with an orifice door that can close or open the ventilation hole.

The aperture door in the above technical solution may be slidably fitted on a slide rail on the inner top surface of the top cover, and a handle is provided on the aperture door to control the opening or closing of the aperture door.

The neck of the closed box described in the above technical solution can be provided with a sealing ring, and the sealing ring can be made of soft non-metallic material. The sealing ring may be composed of a lower half ring disposed on the base and an upper half ring disposed on the top cover that fit together.

The air inlet of the box in the above technical solution can be provided at the foot end of the box, and the air outlet of the box can be provided at the head end of the box.

The breathable lying platform in the lying cavity of the above technical solution can be composed of a lying board placed in the lying cavity, or can be composed of a boss formed integrally with the lying cavity, and the ventilation lying platform is distributed on There are breathable grooves to allow hot air to heat the back of the person being tested.

The heater described in the above technical solution may be provided with an automatic hot air temperature control regulator.

The shapes of the box and the lying cavity in the above technical solution can adopt any applicable shape.

In the above technical solution, the outer portions of the base and the top cover may be provided with corresponding buckles respectively, so that the top cover can be fixed when the top cover is closed on the top side of the base. A sealing gasket may be provided on the snapping edge of the base and the top cover.

The hot air in the above technical solution can be dry hot air or moist hot air, and the heater or the closed box can be provided with a hot air conveying fan.

beneficial effects

The beneficial effects of the present invention are: because the present invention allows the subject to lie in a closed box made of non-metallic material, and the subject's head is exposed outside the closed box, the hot air is transported into the closed box through the heater. In the closed box, the temperature inside the box where the subject is located is controlled and appropriately increased, thereby increasing the heart rate of the subject, increasing myocardial oxygen consumption, and reaching a stress test state. At the same time, a magnetic resonance imaging scanner is used The subject in this load test state is detected and imaged. Therefore, the "heat load method" of the present invention has low cost to obtain the load test state, has no drug side effects on the human body, has good controllability, and can perform real-time dynamic monitoring. There is no need to require the subject to cooperate with exercise, so it is easier and more convenient to reach the stress test state. The stress test state is relatively stable and ideal, which effectively improves the effect of magnetic resonance stress imaging. Since the structure of the invention is perfect and simple, the temperature inside the closed box rises evenly, the testee has good effect in obtaining the load test state, and the use is safe and reliable, the purpose of the invention can be ideally realized.

Description of the drawings

The present invention will be further described below in conjunction with the accompanying drawings and examples.

Figure 1 is a schematic diagram of an embodiment of the present invention.

Figure 2 is a schematic top view of the base of the closed box of Figure 1 with the top cover removed.

Figure 3 is a schematic top view of the top cover of the closed box in Figure 1 .

Figure 4 is a schematic diagram of the top cover of Figure 3 turned over.

In the picture: 1. Closed box; 2. Heater; 3. Box air inlet; 4. Box air outlet; 5. Heater air outlet; 6. Hot air delivery pipe; 7. Neck opening; 8 , lying cavity; 9. base; 10. top cover; 11. breathable lying platform; 12. ventilation hole; 13. first hand-held control balloon; 14. trachea; 15. tube hole; 16. expansion hole 17. Second hand-held control balloon; 18. Connecting pipeline; 19 and 20, orifice door; 21 and 22, slide rail; 23 and 24, handle; 25, lower half circle; 26, upper half circle; 27. Breathable grooves; 28. Automatic hot air temperature control regulator; 29. Buckle; 30. Fastening edge of the base; 31. Fastening edge of the top cover; 32. Hot air delivery fan.

Embodiments of the invention

Referring to Figures 1 to 4, this device for magnetic resonance stress experimental imaging is characterized by: including a closed box 1 for the subject to lie inside and a heater 2 that generates hot air. The box 1 is provided with a box air inlet 3 and a box air outlet 4. The air outlet 5 of the heater 2 is connected to the box air inlet 3 through a hot air delivery pipe 6. The closed box 1 The front end is provided with a neck opening 7 for the subject's head to extend out of the closed box 1. The closed box 1 consists of a base 9 with a lying cavity 8 and a cover that can be covered in the base 9. It consists of a top cover 10 with an opening above the lying chamber 8. A breathable lying platform 11 is provided in the lying chamber 8. The top cover 10 is provided with a ventilation hole 12 that can be opened from inside the box. The entire The closed box 1 is made of non-metallic materials.

In addition, the closed box 1 is provided with a first hand-held control balloon 13 for controlling the heater to stop delivering hot air. The air tube 14 of the first hand-held control balloon 13 passes through the closed box. The body 1 is connected to the pneumatic switch of the heater 2. The pipe opening 15 of the closed box 1 for the trachea 14 of the first hand-held control balloon 13 to pass through is provided with a sealing ring.

The closed box 1 is provided with an expansion opening 16 for external equipment or its operator to be put into the closed box 1. The external equipment or its operator placed into the closed box 1 is a control unit. The magnetic resonance scan pauses the second hand-held control balloon 17 for scanning. The connecting pipeline 18 of the second hand-held control balloon 17 is connected to the docking device outside the closed box 1 through the expansion hole 16, so The expansion opening 16 is provided with a sealing ring.

The ventilation hole 12 on the top cover 10 is composed of several ventilation holes. The inside of the top cover 10 is provided with orifice doors 19 and 20 that can close or open the ventilation hole 12 .

The orifice doors 19 and 20 are slidably fitted on the slide rails 21 and 22 on the inner top surface of the top cover 10. The orifice doors 19 and 20 are respectively provided with handles 23 and 24 for controlling the Closing or opening of orifice doors 19, 20.

The neck opening 7 of the closed box 1 is provided with a sealing ring, and the sealing ring is made of soft non-metallic material. The sealing ring is composed of a lower half ring 25 provided on the base 9 and an upper half ring 26 provided on the top cover 10 that fit together.

The box air inlet 3 is located at the foot end of the base 9 , and the box air outlet 4 is located at the head end of the top cover 10 .

The breathable lying platform 11 in the lying chamber is composed of a boss formed integrally with the lying chamber 8. The breathable lying platform 11 is distributed with ventilation grooves 27 so that the hot air can heat the body of the person being tested. back.

The heater 2 is provided with an automatic hot air temperature control regulator 28 .

The outer parts of the base 9 and the top cover 10 are respectively provided with corresponding buckles 29 and the like, so that the top cover 10 can be fixed when the top cover 10 is closed above the opening of the lying cavity 8 of the base 9 . Sealing gaskets may be provided on the fastening edges 30 and 31 of the base 9 and the top cover 10 .

The hot air output by the heater 2 can be dry hot air or moist hot air. The heater 2 is provided with a hot air conveying fan 32 .

In use, when magnetic resonance imaging requires stress test imaging, the top cover 10 is opened in the state shown in Figure 1, and the base 9 becomes the state shown in Figure 2, and the subject is allowed to lie on the base 9. On the lying platform 11, the subject's neck is pillowed on the lower half ring 25 of the sealing ring, and the head is exposed outside the neck opening 7 of the closed box 1; then the top cover 10 is closed Seal the lying chamber 8 on the open opening above the lying chamber 8 of the base 9; then start the heater 2 to transport hot air into the closed box 1, and the temperature inside the box gradually increases. , the subject's heart rate and myocardial oxygen consumption increase, reaching the stress test state; at this time, the magnetic resonance imaging equipment performs stress experiment imaging detection on the subject in the closed box 1 from outside the closed box 1 ; When the subject feels uncomfortable during the load test state, the first hand-held control balloon 13 can be squeezed to control the heater 2 to stop delivering hot air, and the second hand-held control balloon 13 can be squeezed at the same time. Control the balloon 17 to control the magnetic resonance imaging equipment to pause scanning; then push the handles 23 and 24 to control the opening of the orifice doors 19 and 20 to allow the hot air in the closed box 1 to pass through the ventilation orifice. 12 is discharged to quickly reduce the temperature inside the closed box 1.

Claims

A device for magnetic resonance stress experimental imaging, which is characterized by: including a closed box for a subject to lie inside and a heater that generates hot air. The closed box is provided with a box air inlet. and the air outlet of the box. The air outlet of the heater is connected to the air inlet of the box through a hot air delivery pipe. The front end of the closed box is provided with a head for the subject to extend out of the closed box. The neck opening outside the body, the closed box body is composed of a base with a lying cavity and a top cover that can cover the opening above the lying cavity of the base, and a breathable lying platform is provided in the lying cavity, so The top cover is provided with a ventilation hole that can be opened from inside the box, and the entire closed box is made of non-metallic materials.
The device for magnetic resonance load experiment imaging according to claim 1, characterized in that a first hand-held control balloon is provided in the closed box to control the heater to stop delivering hot air, and the third hand-held control balloon is The trachea of a hand-held control balloon passes through the closed box and is connected to the pneumatic switch of the heater. There is a through-tube hole on the closed box for the trachea of the first hand-held control balloon to pass through. The pad is equipped with a sealing ring.
The device for magnetic resonance stress experimental imaging according to claim 2, characterized in that the closed box is provided with an expansion opening for external equipment or its operator to be placed in the closed box, and the external The connecting pipeline of the equipment or its operator is connected to the docking equipment outside the closed box through the expansion opening, and the expansion opening is provided with a sealing ring.
The device for magnetic resonance stress experiment imaging according to claim 1, 2 or 3, characterized in that the ventilation hole on the top cover is composed of several ventilation holes, and there is a closeable vent hole on the inside of the top cover. Or open the orifice door of said vent.
The device for magnetic resonance load experiment imaging according to claim 4, characterized in that the orifice door is slidably fitted on a slide rail on the inner top surface of the top cover, and the orifice door is provided with A handle to control the opening or closing of the orifice door.
The device for magnetic resonance load experiment imaging according to claim 1, 2 or 3, characterized in that a sealing ring is padded on the neck of the closed box, and the sealing ring is made of soft non-metallic material. The sealing ring is composed of a lower half ring set on the base and an upper half ring set on the top cover that fit together.
The device for magnetic resonance load experiment imaging according to claim 1, 2 or 3, characterized in that the air inlet of the box is located at the foot end of the box, and the air outlet of the box is located at at the head end of the box.
The device for magnetic resonance stress experimental imaging according to claim 1, 2 or 3, characterized in that the breathable lying platform in the lying chamber is composed of a lying board placed in the lying chamber or is made of a The lying cavity is composed of an integrally formed boss, and ventilation grooves are distributed on the breathable lying platform.
The device for magnetic resonance stress experiment imaging according to claim 1, 2 or 3, characterized in that the outer portions of the base and the top cover are respectively provided with corresponding buckles, so that the top cover The cover can be fixed when the top side of the base is open, and a sealing gasket is provided on the snapping edge of the base and the top cover.
The device for magnetic resonance load experiment imaging according to claim 1, 2 or 3, characterized in that the hot air is dry hot air or moist hot air, and the heater or the closed box is provided with There is a hot air delivery fan.